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    Amorphous poly(D,L-lactide) coating
    3.
    发明申请
    Amorphous poly(D,L-lactide) coating 有权
    无定形聚（D，L-丙交酯）涂层

    公开(公告)号：US20060246108A1

    公开(公告)日：2006-11-02

    申请号：US11117813

    申请日：2005-04-29

    申请人： Stephen Pacetti ,  Syed Hossainy ,  David Gale

    发明人： Stephen Pacetti ,  Syed Hossainy ,  David Gale

    IPC分类号： A61F2/00 ,  C08L67/00

    CPC分类号： A61L31/10 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  C08L101/00 ,  C09D167/04 ,  C08L67/04 ,  C08L2666/02

    摘要： Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

    摘要翻译： 提供由包含由诸如内消旋-D，L-丙交酯的原料形成的无定形聚（D，L-丙交酯）的材料形成或涂覆的可植入装置。 可植入装置可用于治疗，缓解，预防或抑制动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，卵圆孔未闭，跛行， 静脉和人造移植物的吻合增殖，胆管阻塞，输尿管阻塞，肿瘤阻塞或其组合。

    Optimizing fracture toughness of polymeric stent
    9.
    发明授权
    Optimizing fracture toughness of polymeric stent 有权
    优化聚合物支架的断裂韧性

    公开(公告)号：US08099849B2

    公开(公告)日：2012-01-24

    申请号：US11639079

    申请日：2006-12-13

    申请人： David Gale ,  Bin Huang ,  Vincent Gueriguian ,  Syed Hossainy

    发明人： David Gale ,  Bin Huang ,  Vincent Gueriguian ,  Syed Hossainy

    IPC分类号： A61F2/06

    CPC分类号： A61F2/95 ,  A61F2/91 ,  A61F2002/9522 ,  A61L31/06 ,  Y10T29/49771 ,  Y10T29/49908 ,  Y10T29/49913 ,  Y10T29/49938 ,  C08L67/04

    摘要： Disclosed herein is a method of fabricating a stent assembly comprising radially expanding a polymeric tube to an optimal degree of radial expansion; fabricating a stent from the expanded polymeric tube; and crimping the stent onto a catheter assembly, wherein the temperature of the stent during crimping is an optimal crimping temperature, wherein the optimal degree of radial expansion and the optimal crimping temperature correspond to an optimal fracture toughness exhibited by the crimped stent upon its deployment as a function of degree of radial expansion and crimping temperature.

    摘要翻译： 本文公开了一种制造支架组件的方法，包括将聚合物管径向膨胀至最佳径向膨胀程度; 从扩张的聚合物管制造支架; 并将支架卷曲到导管组件上，其中在卷曲期间支架的温度是最佳卷曲温度，其中最佳径向膨胀程度和最佳卷曲温度对应于卷曲支架在展开时表现出的最佳断裂韧性 径向膨胀度和卷曲温度的函数。