公开(公告)号：US20180312715A1

公开(公告)日：2018-11-01

申请号：US15768288

申请日：2016-09-23

Applicant: BASF SE

Inventor： Sebastian BERGER ,  Paul SHARE

IPC: C09D135/08 ,  C09J135/08 ,  C09D11/106 ,  C08G64/02 ,  C07C217/28 ,  C07C323/12 ,  C09D135/02 ,  C09J135/02 ,  C09D11/107 ,  C09D11/101 ,  C09D4/00 ,  C09J4/00

CPC classification number: C09D4/00 ,  C07C217/08 ,  C07C323/12 ,  C08F26/02 ,  C08G64/0241 ,  C08G64/025 ,  C08G64/0291 ,  C08G64/42 ,  C09D169/00

Abstract: An ink or coating formulation including an energy curable high reactivity heteroatom-containing polycarbonate polyfunctional-vinyl ether molecule of formula (I) or an energy curable high reactivity heteroatom-containing acrylate molecule of formula (II) is provided.

公开(公告)号：US20170260317A1

公开(公告)日：2017-09-14

申请号：US15454504

申请日：2017-03-09

Applicant: Momentive Performance Materials Inc.

Inventor： Constantine Kondos ,  Nayeem Soad ,  Misty Huang ,  Christine Lacroix ,  Vikram Kumar

IPC: C08G18/28 ,  C09D175/04 ,  C08G18/44 ,  C08G18/66 ,  C08G18/10 ,  C08G18/75

CPC classification number: C08G18/289 ,  C08G18/10 ,  C08G18/12 ,  C08G18/3206 ,  C08G18/44 ,  C08G18/6644 ,  C08G18/718 ,  C08G18/755 ,  C08G18/758 ,  C08G64/0241 ,  C08G64/0266 ,  C08K3/22 ,  C08K2003/2241 ,  C09D169/00 ,  C09D175/04 ,  C09J169/00

Abstract: A moisture-curable silylated resin is derived from a copolycarbonate diol prepared from diol(s) of specific types.

公开(公告)号：US20170226269A1

公开(公告)日：2017-08-10

申请号：US15500266

申请日：2015-08-11

Applicant: POLITECNICO DI MILANO

Inventor： Maurizio Stefano GALIMBERTI ,  Vincenzina BARBERA ,  Ada TRUSCELLO ,  Roberto SEBASTIANO ,  Antonio Marco VALERIO

IPC: C08G18/38 ,  C08G18/73 ,  C08G61/12 ,  C08G63/685 ,  C08G64/02 ,  C08K3/04 ,  C08G65/34

CPC classification number: C08G18/3844 ,  C08G18/44 ,  C08G18/4646 ,  C08G18/5057 ,  C08G18/73 ,  C08G18/8012 ,  C08G18/8058 ,  C08G61/124 ,  C08G63/6856 ,  C08G64/0241 ,  C08G65/34 ,  C08G2261/3221 ,  C08G2261/43 ,  C08G2650/50 ,  C08G2650/56 ,  C08K3/04 ,  C08K3/041 ,  C08K3/042 ,  C08L75/04 ,  C08L69/00 ,  C08L67/02

Abstract: The present invention relates to a polymer comprising repeating units consisting of a substituted pyrrole ring. In particular, the repeating units consist of substituted pyrrole containing polar groups capable of interacting with carbon allotropes such as carbon nanotubes, graphene or nanographites, in order to improve the chemical-physical characteristics of the allotropes mainly by increasing their dispersibility and stability in liquid media and in polymer matrices. The invention also relates to products of addition of these polymers with carbon allotropes in order to obtain easily dispersible macromolecules.

公开(公告)号：US09622476B2

公开(公告)日：2017-04-18

申请号：US14960752

申请日：2015-12-07

Applicant: International Business Machines Corporation ,  Agency for Science, Technology and Research

Inventor： Daniel J. Coady ,  Jeannette M. Garcia ,  James L. Hedrick ,  Jeremy P. K. Tan ,  Yi Yan Yang

IPC: A01N47/06 ,  C07D273/01 ,  C08G64/02 ,  C08G64/42 ,  A01N43/72

CPC classification number: A01N47/06 ,  A01N43/72 ,  C07D273/01 ,  C08G64/0241 ,  C08G64/42

Abstract: Eight-membered ring cyclic carbonates comprising a ring nitrogen at position 6 (1,3,6-dioxazocan-2-ones) were prepared by reaction of precursor diols with active carbonates. The ring nitrogen is linked to a pendant group Y′ via a methylene linking group. The cyclic carbonates undergo organocatalyzed ring opening polymerization to form an initial polycarbonate comprising a backbone tertiary amine group. Quaternization of the initial polycarbonates forms cationic polycarbonates comprising a positive-charged backbone quaternary nitrogen. The cationic polycarbonates can be potent antimicrobial agents.

公开(公告)号：US20150264932A1

公开(公告)日：2015-09-24

申请号：US14223630

申请日：2014-03-24

Applicant: Agency for Science, Technology and Research ,  International Business Machines Corporation

Inventor： Daniel J. Coady ,  Amanda C. Engler ,  Jeanette M. Garcia ,  James L. Hedrick ,  Jeremy P.K. Tan ,  Yi Yan Yang

IPC: A01N47/06 ,  C08G64/02 ,  C07D273/01

CPC classification number: A01N47/06 ,  A01N43/72 ,  C07D273/01 ,  C08G64/0241 ,  C08G64/42

Abstract: Eight-membered ring cyclic carbonates comprising a ring nitrogen at position 6 (1,3,6-dioxazocan-2-ones) were prepared by reaction of precursor diols with active carbonates. The ring nitrogen is linked to a pendant group Y′ via a methylene linking group. The cyclic carbonates undergo organocatalyzed ring opening polymerization to form an initial polycarbonate comprising a backbone tertiary amine group. Quaternization of the initial polycarbonates forms cationic polycarbonates comprising a positive-charged backbone quaternary nitrogen. The cationic polycarbonates can be potent antimicrobial agents.

Abstract translation: 通过前体二醇与活性碳酸酯的反应来制备包含第6位的环氮（1,3,6-二氧杂环己烷-2-酮）的八元环状碳酸酯。 环氮通过亚甲基连接基团与侧基Y'连接。 环状碳酸酯进行有机催化的开环聚合，形成包含主链叔胺基团的初始聚碳酸酯。 初始聚碳酸酯的季铵化形成包含正电荷的主链季氮的阳离子聚碳酸酯。 阳离子聚碳酸酯可以是有效的抗微生物剂。

公开(公告)号：US20150157723A1

公开(公告)日：2015-06-11

申请号：US14097488

申请日：2013-12-05

Applicant: International Business Machines Corporation ,  Universidad del Pais Vasco/Euskal Herriko Unibertsitatea ,  Agency For Science, Technology and Research

Inventor： Julian M. W. Chan ,  Amanda C. Engler ,  James L. Hedrick ,  Xiyu Ke ,  Victor W.L. Ng ,  Haritz Sardon ,  Jeremy P. K. Tan ,  Yi Yan Yang

IPC: A61K47/34 ,  A61K31/713 ,  A61K31/704 ,  A61K38/16

CPC classification number: A61K47/34 ,  A61K9/5146 ,  A61K31/704 ,  A61K31/713 ,  A61K38/00 ,  A61K38/16 ,  C08G64/0241 ,  C08G64/183 ,  C08L69/00

Abstract: Nanoparticles comprise a drug, a first block polymer and a second block polymer. The first block polymer has a poly(ethylene oxide) (PEO) block and a polycarbonate block bearing a side chain aromatic nitrogen-containing heterocycle (N-heterocycle). The N-heterocycle can be in the form of a base, a hydrosalt of the base, a sulfobetaine adduct of the base, or a combination thereof. The second block polymer has a PEO block and a polycarbonate block bearing a side chain catechol group, which can be present as a catechol, oxidized form of a catechol, and/or a polymerized form of a catechol. The nanoparticles can be dispersed in water and are capable of controlled release of the drug.

Abstract translation: 纳米颗粒包含药物，第一嵌段聚合物和第二嵌段聚合物。 第一嵌段聚合物具有聚（环氧乙烷）（PEO）嵌段和带有侧链芳香族含氮杂环（N-杂环）的聚碳酸酯嵌段）。 N-杂环可以是碱的形式，碱的氢盐，碱的磺基甜菜碱加合物或其组合。 第二嵌段聚合物具有PEO嵌段和带有侧链儿茶酚基团的聚碳酸酯嵌段，其可以儿茶酚，氧化形式的儿茶酚和/或邻苯二酚的聚合形式存在。 纳米颗粒可以分散在水中并且能够控制释放药物。

公开(公告)号：US20140301967A1

公开(公告)日：2014-10-09

申请号：US13859037

申请日：2013-04-09

Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION ,  AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Willy Chin ,  Daniel J. Coady ,  Richard A. Dipietro ,  Amanda C. Engler ,  James L. Hedrick ,  Ashlynn L. Z. Lee ,  Victor W. L. Ng ,  Zhan-Yuin Ong ,  Yi Yan Yang

IPC: A61K31/785 ,  A61K31/80

CPC classification number: A61K31/785 ,  A01N33/12 ,  A61K31/80 ,  C08G64/0241 ,  Y02A50/473 ,  A01N25/10

Abstract: Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.

Abstract translation: 通过有机催化开环聚合制备具有一个或两个阳离子聚碳酸酯链的抗微生物阳离子聚合物。 一种抗微生物阳离子聚合物具有基本上由连接到一个或两个端基的阳离子碳酸酯重复单元组成的聚合物链。 末端基团可包含共价结合形式的生物活性化合物如胆固醇。 其它抗微生物阳离子聚合物具有无规共聚碳酸酯链，其包含具有共价结合形式的维生素E和/或维生素D2的疏水重复单元的较小摩尔分数。 阳离子聚合物对革兰氏阴性和革兰氏阳性微生物和真菌表现出高活性和选择性。

公开(公告)号：US08779166B2

公开(公告)日：2014-07-15

申请号：US13414837

申请日：2012-03-08

Applicant: James Lupton Hedrick ,  Alshakim Nelson ,  Daniel Paul Sanders

Inventor： James Lupton Hedrick ,  Alshakim Nelson ,  Daniel Paul Sanders

IPC: C07D221/00

CPC classification number: C08G64/1633 ,  C07D319/06 ,  C08G63/08 ,  C08G63/64 ,  C08G64/0233 ,  C08G64/0241 ,  C08G64/025 ,  C08G64/38 ,  C08G64/42 ,  C08G2261/126 ,  Y02P20/582

Abstract: A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl ester group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl ester group. Using a suitable nucleophile, the pendant pentafluorophenyl ester group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization.

Abstract translation: 公开了一种制备包含活性五氟苯基酯基团的环状羰基化合物的一锅法。 环状羰基化合物可以通过开环方法聚合以形成包含包含侧链五氟苯酯基的重复单元的ROP聚合物。 使用合适的亲核试剂，可以在开环聚合前后选择性地将五氟苯基酯基团转变成多种其它官能团。

公开(公告)号：US20140058058A1

公开(公告)日：2014-02-27

申请号：US14000869

申请日：2012-02-24

Applicant: Jie Song ,  Jianwen Xu

Inventor： Jie Song ,  Jianwen Xu

IPC: C08G64/02 ,  C07D405/14 ,  C07C247/10 ,  C07D319/06

CPC classification number: C07D405/14 ,  A61L27/18 ,  A61L27/52 ,  C07C247/04 ,  C07C247/10 ,  C07D319/06 ,  C07D405/06 ,  C08G64/0208 ,  C08G64/0241 ,  C08G64/0291 ,  C08G64/18 ,  C08G64/183 ,  C08L69/00

Abstract: The invention generally relates to functional polymers and hydrogels. More particularly, the invention provides versatile monomers and polymers with well-defined functionalities, e.g., polycarbonates and poly(ester-carbonates), compositions thereof, and methods for making and using the same. The invention also provides cytocompatible poly(ethylene glycol)-co-polycarobonate hydrogels (e.g., crosslinked by copper-free, strain-promoted “click” chemistry).

Abstract translation: 本发明一般涉及功能聚合物和水凝胶。 更具体地说，本发明提供通用单体和具有良好界定的官能团的聚合物，例如聚碳酸酯和聚（酯 - 碳酸酯），其组合物，以及制备和使用它们的方法。 本发明还提供细胞相容性聚（乙二醇） - 共 - 碳酸氢氧化物水凝胶（例如，通过无铜，应变促进的“点击”化学交联）。

公开(公告)号：US20140046019A1

公开(公告)日：2014-02-13

申请号：US14058640

申请日：2013-10-21

Applicant: Shalaby W. Shalaby ,  Joel T. Corbett ,  David R. Ingam ,  Michael Aaron Vaughn

Inventor： Shalaby W. Shalaby ,  Joel T. Corbett ,  David R. Ingam ,  Michael Aaron Vaughn

IPC: C08G64/02

CPC classification number: C08G18/73 ,  A61L24/0021 ,  A61L27/18 ,  A61L27/52 ,  A61L2430/06 ,  C08G18/12 ,  C08G18/3206 ,  C08G18/341 ,  C08G18/4244 ,  C08G18/428 ,  C08G18/4283 ,  C08G18/44 ,  C08G18/4887 ,  C08G64/0241 ,  C08G2230/00 ,  C08L75/04

Abstract: Hydroswellable, absorbable and non-absorbable, aliphatic, segmented polyurethanes and polyurethane-urea capable of swelling in the biological environment with associated increase in volume of at least 3 percent have more than one type of segments, including those derived from polyethylene glycol and the molecular chains are structurally tailored to allow the use of corresponding formulations and medical devices as carriers for bioactive agents, rheological modifiers of cyanoacrylate-based tissue adhesives, as protective devices for repairing defective or diseased components of articulating joints and their cartilage, and scaffolds for cartilage tissue engineering.

Abstract translation: 能够在生物环境中膨胀的可渗透，可吸收和不可吸收的脂肪族，分段聚氨酯和聚氨酯 - 尿素，其体积增加至少3％具有多于一种类型的链段，包括衍生自聚乙二醇和分子 链条在结构上被定制以允许使用相应的制剂和医疗装置作为生物活性剂的载体，基于氰基丙烯酸酯的组织粘合剂的流变改性剂，作为用于修复关节关节及其软骨的缺陷或患病组分的保护装置，以及用于软骨组织的支架 工程。