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178 条记录 (耗时 0.031 秒)

    Amorphous poly(D,L-lactide) coating
    1.
    发明申请
    Amorphous poly(D,L-lactide) coating 有权
    无定形聚（D，L-丙交酯）涂层

    公开(公告)号：US20060246108A1

    公开(公告)日：2006-11-02

    申请号：US11117813

    申请日：2005-04-29

    申请人： Stephen Pacetti ,  Syed Hossainy ,  David Gale

    发明人： Stephen Pacetti ,  Syed Hossainy ,  David Gale

    IPC分类号： A61F2/00 ,  C08L67/00

    CPC分类号： A61L31/10 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  C08L101/00 ,  C09D167/04 ,  C08L67/04 ,  C08L2666/02

    摘要： Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

    摘要翻译： 提供由包含由诸如内消旋-D，L-丙交酯的原料形成的无定形聚（D，L-丙交酯）的材料形成或涂覆的可植入装置。 可植入装置可用于治疗，缓解，预防或抑制动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔，血管动脉瘤，易损斑块，慢性完全闭塞，卵圆孔未闭，跛行， 静脉和人造移植物的吻合增殖，胆管阻塞，输尿管阻塞，肿瘤阻塞或其组合。

    Poly(ester amide) filler blends for modulation of coating properties
    8.
    发明申请
    Poly(ester amide) filler blends for modulation of coating properties 有权
    用于调节涂层性能的聚（酯酰胺）填料混合物

    公开(公告)号：US20060093842A1

    公开(公告)日：2006-05-04

    申请号：US10976551

    申请日：2004-10-29

    申请人： Jessica DesNoyer ,  Stephen Pacetti ,  Syed Hossainy ,  Lothar Kleiner ,  Yiwen Tang ,  Gina Zhang

    发明人： Jessica DesNoyer ,  Stephen Pacetti ,  Syed Hossainy ,  Lothar Kleiner ,  Yiwen Tang ,  Gina Zhang

    IPC分类号： C08G63/02 ,  C08G69/08 ,  B32B27/34 ,  B32B27/36

    CPC分类号： C09D177/12 ,  A61L31/06 ,  A61L31/10 ,  Y10S623/90 ,  Y10T428/31725 ,  Y10T428/31786 ,  C08L77/12

    摘要： Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and/or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.

    摘要翻译： 本文提供了由其形成的PEA聚合物共混物和涂层或可植入装置。 PEA聚合物共混物由PEA聚合物和能够与PEA氢键合的材料形成。 PEA聚合物共混物可以在可植入装置上形成涂层，其一个实例是支架。 涂层可任选地包括生物有益材料和/或任选地含有生物活性剂。 可植入装置可用于治疗或预防动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔之一，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍 导管阻塞，输尿管阻塞，肿瘤阻塞及其组合。