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公开(公告)号：US11666872B2
公开(公告)日：2023-06-06
申请号：US16659215
申请日：2019-10-21
Applicant: T2 Biosystems, Inc.
Inventor： Adam Suchocki , Mark John Audeh , Matthew Blanco , James Franklin Chepin , Vasiliki Demas , Marilyn Lee Fritzemeier , Thomas Jay Lowery, Jr. , Michael Min , Lori Anne Neely , Charles William Rittershaus , Hwa-Tang Wang , Parris Wellman
IPC: C12N1/06 , B01F29/30 , G01N27/74 , G01N33/49 , C12M1/00 , B65D1/46 , C12Q1/6816 , C12Q1/686 , B01F33/25 , B01F35/53
CPC classification number: B01F29/30 , B01F33/251 , B01F35/53 , B01F35/5312 , B65D1/46 , C12M47/06 , C12N1/066 , C12Q1/686 , C12Q1/6816 , G01N27/745 , G01N33/492 , B01F2215/0431 , B65D2221/00 , C12Q1/6816 , C12Q2523/32 , C12Q2527/146 , C12Q2563/143 , C12Q1/686 , C12Q2523/32 , C12Q2527/146 , C12Q2563/143
Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
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公开(公告)号：US10184907B2
公开(公告)日：2019-01-22
申请号：US14878765
申请日：2015-10-08
Applicant: T2 Biosystems, Inc.
Inventor： Thomas Jay Lowery, Jr. , James Joseph Koziarz , Douglas Adam Levinson , David A. Berry , Tuan A. Elstrom , Sonia Kumar , Mark John Audeh
IPC: G01N24/08 , A61B5/055 , G01N33/543 , A61B5/145 , A61B5/1486 , A61B10/00 , A61B17/00
Abstract: Disclosed are magnetic nanosensors or transducers that permit measurement of a physical parameter in an analyte via magnetic reasonance measurements, in particular of non-agglomerative assays. More particularly, in certain embodiments, the invention relates to designs of nanoparticle reagents and responsive polymer coated magnetic nanoparticles. Additionally provided are methods of use of nanoparticle reagents and responsive polymer coated magnetic nanoparticles for the detection of a stimulus or an analyte with NMR detectors.
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公开(公告)号：US11519016B2
公开(公告)日：2022-12-06
申请号：US16070994
申请日：2017-01-20
Applicant: T2 Biosystems, Inc.
Inventor： Ulrich Hans Thomann , Lori Anne Neely , Heidi Susanne Giese , Jessica Ann Townsend , Rahul Krishan Dhanda , Thomas Jay Lowery, Jr. , Urvi Ved , Brendan Manning , Nu Ai Phung , Joanne Lawton Garver , Benjamin B. Stone
IPC: C12Q1/04 , C12Q1/689 , C12Q1/6825 , C07K14/22 , G01N33/569 , G01N33/68
Abstract: The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
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公开(公告)号：US09632154B2
公开(公告)日：2017-04-25
申请号：US13974477
申请日：2013-08-23
Applicant: T2 Biosystems, Inc.
Inventor： Pablo J. Prado , Thomas Jay Lowery, Jr.
IPC: G01V3/00 , G01R33/44 , G01N24/08 , G01R33/24 , G01R33/30 , G01R33/38 , G01R33/383 , G01R33/465 , G01R33/34
CPC classification number: G01R33/448 , G01N24/08 , G01R33/243 , G01R33/302 , G01R33/307 , G01R33/34053 , G01R33/3806 , G01R33/383 , G01R33/44 , G01R33/465
Abstract: Small and inexpensive probeheads for use in nuclear magnetic resonance systems, in particular, magnetic resonance relaxometry systems are provided. The design of the magnet-radiofrequency coil configurations within the probeheads is guided by an excitation bandwidth associated with radiofrequency pulses to be applied to a sample.
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公开(公告)号：US12077810B2
公开(公告)日：2024-09-03
申请号：US16093488
申请日：2017-04-12
Applicant: T2 Biosystems, Inc.
Inventor： Ulrich Hans Thomann , Jessica Lee Snyder , Thomas Jay Lowery, Jr.
IPC: C12Q1/6848 , C12P19/34 , C12Q1/6806 , C12Q1/6825 , G16B30/00 , G16B30/10
CPC classification number: C12Q1/6848 , C12P19/34 , C12Q1/6806 , C12Q1/6825 , G16B30/00 , G16B30/10
Abstract: The invention features methods, systems, and cartridges for amplification of target nucleic acids in complex samples, for example, whole blood. The invention also features diagnostic and therapeutic methods based on amplification of target nucleic acids characteristic of pathogens present in complex samples containing cells and/or cell debris, for example, whole blood.
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Patent Agency Ranking
公开(公告)号：US09707528B2
公开(公告)日：2017-07-18
申请号：US13650734
申请日：2012-10-12
Applicant: T2 Biosystems, Inc.
Inventor： Adam Suchocki , Mark John Audeh , Matthew Blanco , James Franklin Chepin , Vasiliki Demas , Marilyn Lee Fritzemeier , Thomas Jay Lowery, Jr. , Michael Min , Lori Anne Neely , Charles William Rittershaus , Hwa-Tang Wang , Parris Wellman
IPC: B01F9/00 , B01F13/00 , B01F15/00 , C12Q1/68 , G01N27/74 , G01N33/49 , C12N1/06 , C12M1/00 , B65D1/46
CPC classification number: B01F9/0014 , B01F13/0052 , B01F15/00876 , B01F15/00896 , B01F2215/0431 , B65D1/46 , B65D2221/00 , C12M47/06 , C12N1/066 , C12Q1/6816 , C12Q1/686 , G01N27/745 , G01N33/492 , C12Q2523/32 , C12Q2527/146 , C12Q2563/143
Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.
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公开(公告)号：US09488648B2
公开(公告)日：2016-11-08
申请号：US13852613
申请日：2013-03-28
Applicant: T2 Biosystems, Inc.
Inventor： Lori Anne Neely , Mark John Audeh , Matthew Blanco , James Franklin Chepin , Vasiliki Demas , Rahul K. Dhanda , Thomas Jay Lowery, Jr.
IPC: G01N33/543 , G01N24/08 , G01N27/74 , G01N33/94 , B82Y25/00 , C12Q1/68 , G01R33/09 , G01R33/12 , G01R33/28 , G01R33/30 , G01R33/44 , C12Q1/70
CPC classification number: G01N33/54326 , B82Y25/00 , C12Q1/6825 , C12Q1/6827 , C12Q1/689 , C12Q1/6895 , C12Q1/70 , C12Q1/701 , G01N24/08 , G01N27/745 , G01N33/5434 , G01N33/9493 , G01R33/093 , G01R33/1269 , G01R33/281 , G01R33/302 , G01R33/448 , C12Q2563/143 , C12Q2565/633 , C12Q2563/149 , C12Q2565/113
Abstract: This invention features systems and methods for the detection of analytes, and their use in the treatment and diagnosis of disease.
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公开(公告)号：US11326213B2
公开(公告)日：2022-05-10
申请号：US15545663
申请日：2016-01-21
Applicant: T2 Biosystems, Inc.
Inventor： Ulrich Hans Thomann , Lori Anne Neely , Rahul Krishan Dhanda , Frédéric Sweeney , Thomas Jay Lowery, Jr. , Jessica Ann Townsend , Jessica Lee Snyder , Heidi Susanne Giese , Cheryl Ann Bandoski-Gralinski , Daniella Lynn Logan
Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
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公开(公告)号：US10697984B2
公开(公告)日：2020-06-30
申请号：US15717113
申请日：2017-09-27
Applicant: T2 Biosystems, Inc.
Inventor： Thomas Jay Lowery, Jr. , Vyacheslav Papkov , Walter W. Massefski, Jr. , Rahul K. Dhanda , Edward Chris Thayer
Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
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公开(公告)号：US09739733B2
公开(公告)日：2017-08-22
申请号：US14648124
申请日：2013-12-05
Applicant: T2 Biosystems, Inc.
Inventor： Walter W. Massefski, Jr. , Thomas Jay Lowery, Jr. , Lynell R. Skewis
CPC classification number: G01N24/088 , C12Q1/56 , G01N33/4905 , G01N2333/75 , G01N2800/224 , G01R33/448 , G01R33/465 , G06F19/00 , G16H50/20 , Y02A90/26
Abstract: The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
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