-
公开(公告)号：US4845037A
公开(公告)日：1989-07-04
申请号：US891082
申请日：1986-07-31
IPC分类号： C12N1/20 , A61K20060101 , A61K31/535 , A61K35/74 , A61P31/04 , A61P33/10 , C07G11/00 , C12N20060101 , C12N1/00 , C12N1/06 , C12N5/00 , C12N15/00 , C12P1/00 , C12P1/06 , C12P17/16 , C12P17/18 , C12R1/29
CPC分类号： C12R1/29 , Y10S435/867
摘要： A biologically pure culture of Micromonospora purpureochromogenes ssp. Wuxiensis and its use in an aerobic fermentation process to produce the antibacterial and antiparasitic agent LL-D42067.alpha..
摘要翻译： 一种生物学纯培养的小单孢菌紫色荧光发生物 无锡植物及其在好氧发酵过程中的应用，产生抗菌和抗寄生虫剂LL-D42067α。
-
公开(公告)号：US4551533A
公开(公告)日：1985-11-05
申请号：US593160
申请日：1984-03-26
申请人： Taikwang M. Lee , Donald B. Borders , Joseph J. Goodman , Raymond T. Testa , William M. Maiese , David P. Labeda
发明人： Taikwang M. Lee , Donald B. Borders , Joseph J. Goodman , Raymond T. Testa , William M. Maiese , David P. Labeda
IPC分类号： A23K20/195 , C07D491/16 , C12P17/18 , C07D521/00 , C12N1/20 , C12R1/03
CPC分类号： C07D491/16 , A23K20/195 , C12P17/188 , C12R1/03 , Y10S435/825
摘要： Antibiotic LL-D42067.alpha. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.
摘要翻译： 抗生素LL-D42067α是通过有氧发酵的微生物Actinomadura madurae亚种simaoensis NRRL 15734得到的，可用作抗菌和抗寄生虫剂。
-
公开(公告)号：US4774184A
公开(公告)日：1988-09-27
申请号：US765418
申请日：1985-08-14
申请人： Taikwang M. Lee , Donald B. Borders , Joseph J. Goodman , Raymond T. Testa , William M. Maiese , David P. Labeda
发明人： Taikwang M. Lee , Donald B. Borders , Joseph J. Goodman , Raymond T. Testa , William M. Maiese , David P. Labeda
IPC分类号： A23K20/195 , C07D491/16 , C12P17/18 , C12P17/16 , C12N1/20 , C12R1/03
CPC分类号： C07D491/16 , A23K20/195 , C12P17/188 , C12R1/03 , Y10S435/825
摘要： The invention is a process for the production by fermentation of the antibacterial and antiparasitic agents designated LL-D42067.alpha., to methods for its recovery and concentration from crude solutions and to processes for its purification. The invention includes within its scope the biologically pure culture of the antibiotic.
摘要翻译： 本发明是通过发酵生产名为LL-D42067α的抗细菌剂和抗寄生虫剂的方法，用于从粗溶液中回收和浓缩的方法及其纯化方法。 本发明在其范围内包括抗生素的生物学纯培养。
-
公开(公告)号：US4705688A
公开(公告)日：1987-11-10
申请号：US880230
申请日：1986-06-30
申请人： Guy T. Carter , Michael Greenstein , Joseph J. Goodman , Donald B. Borders , William M. Maiese , Raymond T. Testa
发明人： Guy T. Carter , Michael Greenstein , Joseph J. Goodman , Donald B. Borders , William M. Maiese , Raymond T. Testa
CPC分类号： C12P1/06
摘要： This invention relates to antibiotic LL-E19020.alpha. and LL-E19020.beta. derived from the microorganism Streptomyces lydicus subspecies tanzanius NRRL 18036, which are useful as an antibacterial agent.
摘要翻译： 本发明涉及衍生自微生物链霉菌属（Streptomyces lydicus subspecies tanzanius）NRRL 18036的抗生素LL-E19020α和LL-E19020ββ，其可用作抗菌剂。
-
5.发明授权Method for controlling chronic respiratory disease, fowl cholera and necrotic enteritis in avian species 失效控制禽类物种慢性呼吸道疾病，禽霍乱和坏死性肠炎的方法
公开(公告)号：US4968493A
公开(公告)日：1990-11-06
申请号：US371666
申请日：1989-06-19
申请人： Guy T. Carter , Michael Greenstein , Joseph J. Goodman , Donald B. Borders , William M. Maiese , Raymond T. Testa
发明人： Guy T. Carter , Michael Greenstein , Joseph J. Goodman , Donald B. Borders , William M. Maiese , Raymond T. Testa
IPC分类号： A23K20/195 , C12P1/06
CPC分类号： C12P1/06 , A23K20/195
摘要： This invention provides a method for treating chronic respiratory disease, fowl cholera and necrotic enteritis in infected birds, by orally administering thereto a pharmaceutically effective amount of antibiotic LL-E19020.alpha., antibiotic LL-E19020.beta. or a physiologically acceptable salt thereof.
摘要翻译： 本发明提供一种通过口服给药药用有效量的抗生素LL-E19020α，抗生素LL-E19020β或其生理上可接受的盐来治疗感染禽类的慢性呼吸道疾病，家禽霍乱和坏死性肠炎的方法。
-
公开(公告)号：US4608343A
公开(公告)日：1986-08-26
申请号：US739334
申请日：1985-05-30
申请人： David P. Labeda , Joseph J. Goodman , Donald B. Borders , Raymond T. Testa , John H. E. J. Martin, deceased
发明人： David P. Labeda , Joseph J. Goodman , Donald B. Borders , Raymond T. Testa , John H. E. J. Martin, deceased
CPC分类号： C12P1/06
摘要： This disclosure describes four new antibacterial agents designated LL-C08078.alpha..sub.1, LL-C08078.alpha..sub.2, LL-C08078.alpha..sub.3 and LL-C08078.beta. produced in a microbiological fermentation under controlled conditions using a new strain of a new species of the genus Streptomyces called Streptomyces majorciensis Labeda, sp. nov., and mutants thereof. These new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found. In addition, these agents are active as growth promotants in warm-blooded animals.
摘要翻译： 本公开描述了在受控条件下使用新型链霉菌属的新菌株在微生物发酵中产生的四种新的抗菌剂，称为LL-C08078α1，LL-C08078α2，LL-C08078α3和LL-C08078ββ 称为Streptomyces majorciensis Labeda，sp。 nov。及其突变体。 这些新的抗菌剂对各种微生物具有活性，因此可用于抑制这些细菌的生长。 此外，这些试剂在温血动物中作为生长促进剂是有活性的。
-
7.发明授权Antibacterial antibiotics LL-CO8078.alpha..sub.1, .alpha..sub.2, .alpha..sub.3 and .beta. 失效抗菌抗生素LL-CO8078 alpha 1，α2，α3和β
公开(公告)号：US4534970A
公开(公告)日：1985-08-13
申请号：US507184
申请日：1983-06-23
申请人： David P. Labeda , Joseph J. Goodman , Donald B. Borders , Raymond T. Testa , John H. E. J. Martin, deceased
发明人： David P. Labeda , Joseph J. Goodman , Donald B. Borders , Raymond T. Testa , John H. E. J. Martin, deceased
CPC分类号： C12P1/06
摘要： This disclosure describes four new antibacterial agents designated LL-CO8078.alpha..sub.1, LL-CO8078.alpha..sub.2, LL-CO8078.alpha..sub.3 and LL-CO8078.beta. produced in a microbiological fermentation under controlled conditions using a new strain of a new species of the genus Streptomyces called Streptomyces majorciensis Labeda, sp. nov., and mutants thereof. These new antibacterial agents are active against a variety of microorganisms and thus are useful in inhibiting the growth of such bacteria wherever they may be found. In addition, these agents are active as growth promotants in warm-blooded animals.
摘要翻译： 本公开描述了在受控条件下使用新型链霉菌属的新菌株在微生物发酵中产生的四种新的抗菌剂，称为LL-CO8078α1，LL-CO8078α2，LL-CO8078α3和LL-CO8078β 称为Streptomyces majorciensis Labeda，sp。 nov。及其突变体。 这些新的抗菌剂对各种微生物具有活性，因此可用于抑制这些细菌的生长。 此外，这些试剂在温血动物中作为生长促进剂是有活性的。
-
公开(公告)号：US4578468A
公开(公告)日：1986-03-25
申请号：US593159
申请日：1984-03-26
IPC分类号： A23K20/195 , A61K31/47 , A61P33/00 , A61P33/02 , C07D319/00 , C07D491/16 , C12P17/18 , C12R1/03 , C07D498/12
CPC分类号： C07D491/16 , A23K20/195 , C12P17/188 , C12R1/03
摘要： Antibiotic LL-D42067.beta. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.
摘要翻译： 抗生素LL-D42067通过有氧发酵得到的微生物Actinomadura madurae亚种simaoensis NRRL 15734，可用作抗菌和抗寄生虫剂。
-
公开(公告)号：US4859598A
公开(公告)日：1989-08-22
申请号：US820048
申请日：1986-01-21
IPC分类号： A23K20/195 , C07D491/16 , C12P17/18
CPC分类号： C07D491/16 , A23K20/195 , C12P17/188 , C12R1/03 , Y10S435/825
摘要： Antibiotic LL-D42067.beta. derived by aerobic fermentation of the microorganism Actinomadura madurae subspecies simaoensis NRRL 15734, useful as an antibacterial and antiparasitic agent.
摘要翻译： 抗生素LL-D42067通过有氧发酵得到的微生物Actinomadura madurae亚种simaoensis NRRL 15734，可用作抗菌和抗寄生虫剂。
-
10.发明授权公开(公告)号：US07868135B2
公开(公告)日：2011-01-11
申请号：US10880442
申请日：2004-06-28
申请人： Dale R. Cameron , Vincent A. Boyd , Richard A. Leese , William V. Curran , Donald B. Borders , Paulo W. M. Sgarbi , Shirley A. Wacowich-Sgarbi , Matthew Nodwell , Yuchen Chen , Qi Jia , Dominique Dugourd
发明人： Dale R. Cameron , Vincent A. Boyd , Richard A. Leese , William V. Curran , Donald B. Borders , Paulo W. M. Sgarbi , Shirley A. Wacowich-Sgarbi , Matthew Nodwell , Yuchen Chen , Qi Jia , Dominique Dugourd
IPC分类号： A61K38/12
摘要： The present invention provides derivatives of lipopeptide antibiotics that display antimicrobial activity against microorganisms, methods and compounds for synthesizing such antimicrobial derivatives and analogues, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of microbial infections.
摘要翻译： 本发明提供显示抗微生物抗微生物活性的脂肽抗生素衍生物，用于合成这种抗微生物衍生物和类似物的方法和化合物，以及在多种情况下使用该化合物的方法，包括在治疗和预防微生物感染中。
-
-
-
-
-
-
-
-
-
搜索结果
29 条记录 (耗时 0.025 秒)
