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    Whitening composition containing reduced coenzyme Q
    2.
    发明申请
    Whitening composition containing reduced coenzyme Q 审中-公开
    含有还原型辅酶Q的美白组合物

    公开(公告)号：US20070196349A1

    公开(公告)日：2007-08-23

    申请号：US11653974

    申请日：2007-01-17

    申请人： Shiro Kitamura ,  Takahiro Ueda ,  Yasuyoshi Ueda ,  Hideyuki Kishida ,  Kenji Fujii ,  Kazunori Hosoe

    发明人： Shiro Kitamura ,  Takahiro Ueda ,  Yasuyoshi Ueda ,  Hideyuki Kishida ,  Kenji Fujii ,  Kazunori Hosoe

    IPC分类号： A61K8/18

    CPC分类号： A61Q19/02 ,  A23L33/10 ,  A23V2002/00 ,  A61K8/355 ,  A23V2200/318 ,  A23V2250/314

    摘要： The present invention provides a cosmetic or food composition which is excellent in a skincare effect, particularly an effect of whitening the skin browned due to ultraviolet radiation or aging, and which can be safely used for many mammals. The present invention provides a whitening composition comprising reduced coenzyme Q represented by formula (1) as an effective component: wherein n represents an integer of 1 to 12. The present invention also provides a whitening composition further comprising oxidized coenzyme Q represented by formula (2) as an effective component: wherein n represents an integer of 1 to 12. The present invention also provides a method for whitening the skin of a mammal, the method comprising administering the mammal with the composition.

    摘要翻译： 本发明提供一种护肤效果优异的化妆品或食品组合物，特别是由于紫外线照射或老化而使皮肤变白而变白的效果，可以安全地用于许多哺乳动物。 本发明提供一种美白组合物，其包含由式（1）表示的还原型辅酶Q作为有效成分：其中n表示1〜12的整数。本发明还提供了还含有由式（2）表示的氧化型辅酶Q ）作为有效成分：其中n表示1至12的整数。本发明还提供了一种使哺乳动物的皮肤变白的方法，所述方法包括给哺乳动物施用该组合物。

    Stabilization method of reduced coenzyme Q10
    4.
    发明授权
    Stabilization method of reduced coenzyme Q10 有权
    还原型辅酶Q10的稳定化方法

    公开(公告)号：US07829080B2

    公开(公告)日：2010-11-09

    申请号：US11741290

    申请日：2007-04-27

    申请人： Takahiro Ueda ,  Shiro Kitamura ,  Hiroshi Kubo ,  Kazunori Hosoe

    发明人： Takahiro Ueda ,  Shiro Kitamura ,  Hiroshi Kubo ,  Kazunori Hosoe

    IPC分类号： A61K9/64 ,  A61K38/43 ,  A61K38/54

    CPC分类号： A61K31/047 ,  A61K9/4858

    摘要： The present invention provides a method for stabilizing reduced coenzyme Q10, which is useful as a food, nutritional product, nutritional supplement, animal drug, drink, feed, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like. The present invention also provides a method of producing a reduced coenzyme Q10-containing composition which includes the co-presence of reduced coenzyme Q10 and reduced coenzyme Q9 and/or reduced coenzyme Q11.

    摘要翻译： 本发明提供一种用于稳定还原型辅酶Q10的方法，其可用作食品，营养产品，营养补充剂，动物药物，饮料，饲料，化妆品，药​​物，治疗药物，预防药物等。 本发明还提供了还原型辅酶Q 10组合物的制造方法，该组合物包括还原型辅酶Q 10和还原型辅酶Q 9和/或还原型辅酶Q 11的共存。

    Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal
    8.
    发明授权
    Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal 有权
    具有优异稳定性的还原型辅酶Q10晶体，含有所述还原型辅酶Q10晶体的组合物

    公开(公告)号：US07358402B2

    公开(公告)日：2008-04-15

    申请号：US10938431

    申请日：2004-09-09

    申请人： Takahiro Ueda ,  Shiro Kitamura ,  Taizo Kawabe ,  Hideyuki Kishida ,  Yasuyoshi Ueda

    发明人： Takahiro Ueda ,  Shiro Kitamura ,  Taizo Kawabe ,  Hideyuki Kishida ,  Yasuyoshi Ueda

    IPC分类号： C07C43/20 ,  C07C43/215

    CPC分类号： C07C43/23 ,  A23L33/10

    摘要： The present invention provides a reduced coenzyme Q10 crystal with excellent stability and a composition containing said reduced coenzyme Q10 crystals.According to the present invention, after dissolving reduced coenzyme Q10 in a fat and oil, it is cooled, making it possible to obtain reduced coenzyme Q10 crystals with excellent stability and which exhibit an x-ray diffraction pattern (using a CuKα emission line) that differs from ordinary reduced coenzyme Q10 crystals. Moreover, said crystals are also excellent in bioabsorbability.

    摘要翻译： 本发明提供了具有优异稳定性的还原型辅酶Q 10 O 2结晶和含有所述还原型辅酶Q 10 O 2结晶的组合物。 根据本发明，在将脂肪和油中的还原型辅酶Q 10 O溶解后，将其冷却，可以获得具有优异稳定性的还原型辅酶Q 10 N 2结晶， 其表现出与普通还原​​型辅酶Q 10 N结晶不同的x射线衍射图（使用CuKα发射谱线）。 此外，所述晶体的生物吸收性也优异。

    REDUCED COENZYME Q10-CONTAINING PARTICULATE COMPOSITION AND METHOD FOR PRODUCING THE SAME
    10.
    发明申请
    REDUCED COENZYME Q10-CONTAINING PARTICULATE COMPOSITION AND METHOD FOR PRODUCING THE SAME 审中-公开
    减少聚碳酸酯Q10-含有颗粒组合物及其生产方法

    公开(公告)号：US20100092560A1

    公开(公告)日：2010-04-15

    申请号：US12579731

    申请日：2009-10-15

    申请人： Shinsuke Akao ,  Takashi Ueda ,  Takahiro Ueda ,  Yozo Nagira ,  Hideyuki Kishida

    发明人： Shinsuke Akao ,  Takashi Ueda ,  Takahiro Ueda ,  Yozo Nagira ,  Hideyuki Kishida

    IPC分类号： A61K38/43 ,  A61K31/122 ,  A23L1/30 ,  A23B4/03

    CPC分类号： A61K9/0095 ,  A23F3/163 ,  A23L33/10 ,  A23L33/15 ,  A23P10/30 ,  A23V2002/00 ,  A61K9/0056 ,  A61K9/2054 ,  A61K9/4858 ,  A23V2200/224 ,  A23V2250/5028 ,  A23V2250/708 ,  A23V2250/314

    摘要： The present invention aims to propose a particulate composition containing reduced coenzyme Q10, which simultaneously shows high oxidative stability and high absorbability in the body and a production method thereof, as well as a stabilizing method thereof, to be used in the fields of foods, foods with nutrient function claims, foods for specified health uses, nutritional supplements, nutritional products, animal drugs, beverages, feeds, cosmetics, pharmaceuticals, therapeutic drugs, prophylactic drugs and the like. The present inventors have conducted intensive studies in an attempt to solve the aforementioned problems and found that a particulate composition containing reduced coenzyme Q10, wherein an oil component containing the reduced coenzyme Q10 is polydispersed forming a domain in a matrix containing a water-soluble excipient as a main component and a water-soluble ascorbic acid is a composition simultaneously having high oxidative stability and high absorbability in the body, and completed the present invention.

    摘要翻译： 本发明的目的是提出一种含有还原型辅酶Q10的颗粒组合物，其还具有在体内的高氧化稳定性和高吸收性及其制备方法及其稳定化方法，用于食品，食品领域 营养功能要求，特定健康用途的食品，营养补充剂，营养产品，动物药物，饮料，饲料，化妆品，药​​物，治疗药物，预防药物等。 为了解决上述问题，本发明人进行了深入研究，发现含有还原型辅酶Q10的微粒组合物，其中含有还原型辅酶Q10的油性成分多分散，在含有水溶性赋形剂的基质中形成结构域 主要成分和水溶性抗坏血酸是同时具有高氧化稳定性和高吸收性的组合物，完成了本发明。