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公开(公告)号：US20070196349A1
公开(公告)日：2007-08-23
申请号：US11653974
申请日：2007-01-17
申请人： Shiro Kitamura , Takahiro Ueda , Yasuyoshi Ueda , Hideyuki Kishida , Kenji Fujii , Kazunori Hosoe
发明人： Shiro Kitamura , Takahiro Ueda , Yasuyoshi Ueda , Hideyuki Kishida , Kenji Fujii , Kazunori Hosoe
IPC分类号： A61K8/18
CPC分类号： A61Q19/02 , A23L33/10 , A23V2002/00 , A61K8/355 , A23V2200/318 , A23V2250/314
摘要： The present invention provides a cosmetic or food composition which is excellent in a skincare effect, particularly an effect of whitening the skin browned due to ultraviolet radiation or aging, and which can be safely used for many mammals. The present invention provides a whitening composition comprising reduced coenzyme Q represented by formula (1) as an effective component: wherein n represents an integer of 1 to 12. The present invention also provides a whitening composition further comprising oxidized coenzyme Q represented by formula (2) as an effective component: wherein n represents an integer of 1 to 12. The present invention also provides a method for whitening the skin of a mammal, the method comprising administering the mammal with the composition.
摘要翻译： 本发明提供一种护肤效果优异的化妆品或食品组合物，特别是由于紫外线照射或老化而使皮肤变白而变白的效果，可以安全地用于许多哺乳动物。 本发明提供一种美白组合物，其包含由式（1）表示的还原型辅酶Q作为有效成分：其中n表示1〜12的整数。本发明还提供了还含有由式（2）表示的氧化型辅酶Q ）作为有效成分：其中n表示1至12的整数。本发明还提供了一种使哺乳动物的皮肤变白的方法，所述方法包括给哺乳动物施用该组合物。
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公开(公告)号：US08562975B2
公开(公告)日：2013-10-22
申请号：US10501698
申请日：2003-01-20
申请人： Yasuyoshi Ueda , Takahiro Ueda , Tadao Ono , Shiro Kitamura , Kenji Fujii , Kazunori Hosoe
发明人： Yasuyoshi Ueda , Takahiro Ueda , Tadao Ono , Shiro Kitamura , Kenji Fujii , Kazunori Hosoe
IPC分类号： A61K38/43
CPC分类号： A61K8/347 , A23D9/007 , A23K20/105 , A23L33/10 , A23V2002/00 , A61K8/345 , A61K8/355 , A61K8/375 , A61K8/39 , A61K8/92 , A61K8/922 , A61K8/925 , A61K31/122 , A61K47/10 , A61K47/14 , A61K2800/52 , A61Q19/00 , C07C41/46 , C07C43/23 , A23V2250/314 , A23V2250/1842 , A23V2250/18 , A23V2250/192 , A23V2250/1944
摘要： The present invention relates to a method for stabilizing reduced coenzyme Q10, which is useful as an ingredient in good foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc., and to a composition therefor. The composition comprises reduced coenzyme Q10, a fat and oil (excluding olive oil) and/or a polyol, and doesn't substantially inhibit the stabilization of reduced coenzyme Q10. Additionally, the composition is a reduced coenzyme Q10-containing composition which comprises reduced coenzyme Q10, a polyglycerol fatty acid ester, and a fat and oil and/or a polyol.
摘要翻译： 本发明涉及一种用于稳定还原型辅酶Q10的方法，其可用作良好食品中的成分，功能营养食品，特定保健食品，营养补充剂，营养物质，动物药物，饮料，饲料，化妆品，药物，补救剂，预防剂 药物等，以及其组合物。 组合物包含还原型辅酶Q10，脂肪和油（不包括橄榄油）和/或多元醇，并且基本上不抑制还原型辅酶Q10的稳定化。 此外，该组合物是还原型辅酶Q 10组合物，其包含还原型辅酶Q10，聚甘油脂肪酸酯和脂肪和油和/或多元醇。
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公开(公告)号：US20080152636A1
公开(公告)日：2008-06-26
申请号：US11896976
申请日：2007-09-07
申请人： Takahiro Ueda , Shiro Kitamura , Yoshiyuki Shinagawa , Taizou Kawabe , Hideyuki Kishida , Kazunori Hosoe
发明人： Takahiro Ueda , Shiro Kitamura , Yoshiyuki Shinagawa , Taizou Kawabe , Hideyuki Kishida , Kazunori Hosoe
IPC分类号： A61K8/35
CPC分类号： A23K20/10 , A23K20/158 , A23L33/10 , A61K8/347 , A61K8/553 , A61K9/08 , A61K31/122 , A61Q19/00
摘要： The present invention provides a method of improving the absorbability of reduced coenzyme Q10, which includes affording a composition containing lysolecithin and reduced coenzyme Q10 in combination. The composition containing lysolecithin and reduced coenzyme Q10 of the present invention shows superior absorption of reduced coenzyme Q10 and can be utilized for food, food with nutrient function, food for specified health uses, nutritional supplement, nutritional product, animal drug, beverage, feed, pet food, cosmetics, pharmaceutical product, therapeutic drug, preventive drug and the like.
摘要翻译： 本发明提供了提高还原型辅酶Q 10的吸收性的方法，其包括组合物提供含有溶血卵磷脂和还原型辅酶Q 10的组合物。 含有本发明的溶血卵磷脂和还原型辅酶Q 10的组合物显示出优异的还原型辅酶Q 10的吸收，并且可以用于食品，具有营养功能的食物，具体的食品 保健用品，营养补充剂，营养制品，动物药，饮料，饲料，宠物食品，化妆品，药品，治疗药物，预防药物等。
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公开(公告)号：US20050147598A1
公开(公告)日：2005-07-07
申请号：US10501698
申请日：2003-01-20
申请人： Yasuyoshi Ueda , Takahiro Ueda , Tadao Ono , Shiro Kitamura , Kazunori Hosoe
发明人： Yasuyoshi Ueda , Takahiro Ueda , Tadao Ono , Shiro Kitamura , Kazunori Hosoe
IPC分类号： A23D9/007 , A23K1/16 , A23L1/30 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/39 , A61K8/92 , A61K31/122 , A61K47/10 , A61K47/14 , A61P3/00 , A61Q19/00 , C07C41/46 , C07C43/23 , A61K38/43 , A61K31/075 , A61K35/78
CPC分类号： A61K8/347 , A23D9/007 , A23K20/105 , A23L33/10 , A23V2002/00 , A61K8/345 , A61K8/355 , A61K8/375 , A61K8/39 , A61K8/92 , A61K8/922 , A61K8/925 , A61K31/122 , A61K47/10 , A61K47/14 , A61K2800/52 , A61Q19/00 , C07C41/46 , C07C43/23 , A23V2250/314 , A23V2250/1842 , A23V2250/18 , A23V2250/192 , A23V2250/1944
摘要： The present invention relates to a method for stabilizing reduced coenzyme Q10, which is useful as an ingredient in good foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc., and to a composition therefor. The composition comprises reduced coenzyme Q10, a fat and oil (excluding olive oil) and/or a polyol, and doesn't substantially inhibit the stabilization of reduced coenzyme Q10. Additionally, the composition is a reduced coenzyme Q10-containing composition which comprises reduced coenzyme Q10, a polyglycerol fatty acid ester, and a fat and oil and/or a polyol.
摘要翻译： 本发明涉及用于稳定还原型辅酶Q 10的方法，其可用作良好食品中的成分，功能营养食品，特定健康食品，营养补充剂，营养物，动物药物，饮料，饲料 ，化妆品，药品，补救措施，预防药品等，以及其组成。 组合物包含还原型辅酶Q 10，脂肪和油（不包括橄榄油）和/或多元醇，并且基本上不抑制还原型辅酶Q 10的稳定化， 。 另外，该组合物是含有还原型辅酶Q 10 N的组合物，其包含还原型辅酶Q 10，聚甘油脂肪酸酯和脂肪和油和/或多元醇 。
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5.发明申请Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal 有权具有优异稳定性的还原型辅酶Q10晶体，含有所述还原型辅酶Q10晶体的组合物公开(公告)号：US20050074860A1
公开(公告)日：2005-04-07
申请号：US10938431
申请日：2004-09-09
摘要： The present invention provides a reduced coenzyme Q10 crystal with excellent stability and a composition containing said reduced coenzyme Q10 crystals. According to the present invention, after dissolving reduced coenzyme Q10 in a fat and oil, it is cooled, making it possible to obtain reduced coenzyme Q10 crystals with excellent stability and which exhibit an x-ray diffraction pattern (using a CuKα emission line) that differs from ordinary reduced coenzyme Q10 crystals. Moreover, said crystals are also excellent in bioabsorbability.
摘要翻译： 本发明提供具有优异稳定性的还原型辅酶Q10晶体和含有所述还原型辅酶Q10晶体的组合物。 根据本发明，在将脂肪和油中的还原型辅酶Q10溶解后，将其冷却，可以获得稳定性优异的还原型辅酶Q10晶体，并显示出X射线衍射图（使用CuKα发射线） 与普通还原型辅酶Q10晶体不同。 此外，所述晶体的生物吸收性也优异。
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6.发明授权Reduced coenzyme Q10 crystal with excellent stability and composition containing said reduced coenzyme Q10 crystal 有权具有优异稳定性的还原型辅酶Q10晶体，含有所述还原型辅酶Q10晶体的组合物公开(公告)号：US07358402B2
公开(公告)日：2008-04-15
申请号：US10938431
申请日：2004-09-09
IPC分类号： C07C43/20 , C07C43/215
摘要： The present invention provides a reduced coenzyme Q10 crystal with excellent stability and a composition containing said reduced coenzyme Q10 crystals.According to the present invention, after dissolving reduced coenzyme Q10 in a fat and oil, it is cooled, making it possible to obtain reduced coenzyme Q10 crystals with excellent stability and which exhibit an x-ray diffraction pattern (using a CuKα emission line) that differs from ordinary reduced coenzyme Q10 crystals. Moreover, said crystals are also excellent in bioabsorbability.
摘要翻译： 本发明提供了具有优异稳定性的还原型辅酶Q 10 O 2结晶和含有所述还原型辅酶Q 10 O 2结晶的组合物。 根据本发明，在将脂肪和油中的还原型辅酶Q 10 O溶解后，将其冷却，可以获得具有优异稳定性的还原型辅酶Q 10 N 2结晶， 其表现出与普通还原型辅酶Q 10 N结晶不同的x射线衍射图（使用CuKα发射谱线）。 此外，所述晶体的生物吸收性也优异。
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公开(公告)号：US20050226858A1
公开(公告)日：2005-10-13
申请号：US11101437
申请日：2005-04-08
申请人： Shiro Kitamura , Takahiro Ueda , Kenji Fujii , Yasuyoshi Ueda
发明人： Shiro Kitamura , Takahiro Ueda , Kenji Fujii , Yasuyoshi Ueda
IPC分类号： A61K31/015 , A61K31/07 , A61K38/43
CPC分类号： A61K31/015 , A61K31/07 , A61K2300/00
摘要： A composition having an antioxidative activity, especially, having a sufficient activity for removing active oxygen and/or free radicals is provided. The composition includes both reduced coenzyme Q10 and a carotenoid, and the activity for removing active oxygen and/or free radicals is synergistically enhanced. A method for removing active oxygen and/or free radicals by using the composition containing both reduced coenzyme Q10 and a carotenoid is also provided.
摘要翻译： 提供具有抗氧化活性的组合物，特别是具有足够的活性氧和/或自由基活性的活性。 该组合物包括还原型辅酶Q 10和类胡萝卜素，并且促进除去活性氧和/或自由基的活性协同增强。 还提供了通过使用含有还原型辅酶Q 10和类胡萝卜素的组合物除去活性氧和/或自由基的方法。
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公开(公告)号：US20070258966A1
公开(公告)日：2007-11-08
申请号：US11741290
申请日：2007-04-27
申请人： Takahiro UEDA , Shiro Kitamura , Hiroshi Kubo , Kazunori Hosoe
发明人： Takahiro UEDA , Shiro Kitamura , Hiroshi Kubo , Kazunori Hosoe
CPC分类号： A61K31/047 , A61K9/4858
摘要： The present invention provides a method for stabilizing reduced coenzyme Q10, which is useful as a food, nutritional product, nutritional supplement, animal drug, drink, feed, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like. The present invention also provides a method of producing a reduced coenzyme Q10-containing composition which includes the co-presence of reduced coenzyme Q10 and reduced coenzyme Q9 and/or reduced coenzyme Q11.
摘要翻译： 本发明提供了用于稳定还原型辅酶Q 10的方法，其可用作食品，营养产品，营养补充剂，动物药物，饮料，饲料，化妆品，药物产品，治疗药物，预防药物 等等。 本发明还提供一种制备还原型辅酶Q 10系组合物的方法，该组合物包括还原型辅酶Q 10和还原型辅酶Q 9的共存 和/或还原型辅酶Q 11。
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公开(公告)号：US07829080B2
公开(公告)日：2010-11-09
申请号：US11741290
申请日：2007-04-27
申请人： Takahiro Ueda , Shiro Kitamura , Hiroshi Kubo , Kazunori Hosoe
发明人： Takahiro Ueda , Shiro Kitamura , Hiroshi Kubo , Kazunori Hosoe
CPC分类号： A61K31/047 , A61K9/4858
摘要： The present invention provides a method for stabilizing reduced coenzyme Q10, which is useful as a food, nutritional product, nutritional supplement, animal drug, drink, feed, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like. The present invention also provides a method of producing a reduced coenzyme Q10-containing composition which includes the co-presence of reduced coenzyme Q10 and reduced coenzyme Q9 and/or reduced coenzyme Q11.
摘要翻译： 本发明提供一种用于稳定还原型辅酶Q10的方法，其可用作食品，营养产品，营养补充剂，动物药物，饮料，饲料，化妆品，药物，治疗药物，预防药物等。 本发明还提供了还原型辅酶Q 10组合物的制造方法，该组合物包括还原型辅酶Q 10和还原型辅酶Q 9和/或还原型辅酶Q 11的共存。
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10.发明授权公开(公告)号：US09295656B2
公开(公告)日：2016-03-29
申请号：US11812887
申请日：2007-06-22
申请人： Takashi Ueda , Shinsuke Akao , Shiro Kitamura , Hideyuki Kishida , Takahiro Ueda
发明人： Takashi Ueda , Shinsuke Akao , Shiro Kitamura , Hideyuki Kishida , Takahiro Ueda
CPC分类号： C07C50/28 , A61K9/0056 , A61K9/107 , A61K9/1652 , A61K9/1664 , A61K9/2018 , A61K9/4858 , A61K9/4875 , A61K31/122
摘要： The present invention provides a particulate composition wherein an oil component containing reduced coenzyme Q10 is polydispersed forming a domain in a matrix containing a water-soluble excipient, which simultaneously shows high oxidative stability and high oral absorbability, a production method thereof, and a stabilizing method thereof. It also provides a food, food with nutrient function claims, food for specified health uses, dietary supplement, nutritional product, animal drug, drink, feed, pet food, cosmetic, pharmaceutical product, therapeutic drug, prophylactic drug and the like, which contain the composition.
摘要翻译： 本发明提供了一种颗粒组合物，其中含有还原型辅酶Q10的油成分是多分散的，在含有水溶性赋形剂的基质中形成一个结构域，其同时表现出高氧化稳定性和高口服吸收性，其制备方法和稳定化方法 其中。 它还提供食物，具有营养功能的食物，特定健康用途的食物，膳食补充剂，营养产品，动物药物，饮料，饲料，宠物食品，化妆品，药物，治疗药物，预防药物等，其含有 组成。
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