摘要:
A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof:wherein, R1 represents a hydrogen atom, a lower alkyl group, a lower alkyloxy group, or a halogen atom; R2 represents a hydroxyl group, or a lower alkyloxy group; R3 represents a hydrogen atom, a lower alkyl group, or a halogen atom; R4 represents a hydrogen atom or a lower alkyloxy group; R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6; R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5; R7 represents a hydrogen atom or a lower alkyl group; and R8 represents a hydrogen atom, a hydroxyl group, an amino group, or a lower alkylcarbonyloxy group (excluding the case where R1, R3, R4 and R7 are hydrogen atoms, R2 and R8 are hydroxyl groups, and R5 and R6 are methoxy groups).
摘要:
A novel compound having an excellent NFκB inhibitory effect is provided. Specifically disclosed is a compound represented by the following formula (1) or a salt thereof: wherein, R1 represents a hydrogen atom, a lower alkyl group, or the like; R2 represents a hydrogen atom, a lower alkyl group, a halogen atom, or the like; R3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group, or a halogen atom; R4 represents a hydrogen atom or a lower alkyloxy group; R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6; R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5; R7 represents a hydrogen atom or a lower alkyl group; and R8 represents a hydrogen atom, a hydroxyl group, an amino group, a lower alkylcarbonyloxy group, or a halogen atom.
摘要:
A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof:wherein, R1 represents a hydrogen atom, a lower alkyl group, a lower alkyloxy group, or a halogen atom;R2 represents a hydroxyl group, or a lower alkyloxy group;R3 represents a hydrogen atom, a lower alkyl group, or a halogen atom;R4 represents a hydrogen atom or a lower alkyloxy group;R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6;R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5;R7 represents a hydrogen atom or a lower alkyl group; andR8 represents a hydrogen atom, a hydroxyl group, an amino group, or a lower alkylcarbonyloxy group (excluding the case where R1, R3, R4 and R7 are hydrogen atoms, R2 and R8 are hydroxyl groups, and R5 and R6 are methoxy groups).
摘要:
A novel compound having an excellent NFκB inhibitory effect is provided. Specifically disclosed is a compound represented by the following formula (1) or a salt thereof: wherein, R1 represents a hydrogen atom, a lower alkyl group, or the like; R2 represents a hydrogen atom, a lower alkyl group, a halogen atom, or the like; R3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group, or a halogen atom; R4 represents a hydrogen atom or a lower alkyloxy group; R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6; R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5; R7 represents a hydrogen atom or a lower alkyl group; and R8 represents a hydrogen atom, a hydroxyl group, an amino group, a lower alkylcarbonyloxy group, or a halogen atom.
摘要:
A floor-standing air-conditioning apparatus includes a lower air inlet, an air outlet having an air outlet opening, a heat exchanger that is provided in the body, a crossflow fan that is provided in the body and produces a flow of air in which the air that has flowed into the body passes through the heat exchanger and is guided to the air outlet, a drain pan that is provided below the heat exchanger in the height direction of the body. The heat exchanger includes a front heat exchanger and a rear heat exchanger, a pair of which form a V shape with their lower ends being in contact with, or in proximity to, each other, and are arranged so that the crossflow fan is positioned between the front heat exchanger and the rear heat exchanger.
摘要:
There has been a problem of dew condensation, during a cooling operation, on a wind vane or the like provided at an air outlet because the wind speed of blown air leaking from ends in longitudinal direction of the air outlet is low, causing the entanglement of room air. Walls that form an air outlet from which air that has exchanged heat in a heat exchanger is blown are provided. End portions of each of the walls in a longitudinal direction of the air outlet have respective recesses such that a passage of the air therein is made wider than in a central portion of the wall. In the longitudinal direction of the air outlet, the recesses each have a downstream-side width that is smaller than an upstream-side width.
摘要:
A cross flow fan including an impeller having at least two rings arranged with intervals in a fan rotation axis O direction and a plurality of blades that are arranged, between correlated rings, with intervals in a circumferential direction of the rings, in which the blade is divided into plural areas in the fan rotation axis O direction, and both ends adjacent to the rings are denoted as the blade-ring proximate sections and the center portion of the blade is denoted as the inter-blade-ring center section. The blade is formed such that the thickness of the inner peripheral blade end of the blade that is the inner peripheral end of the impeller is smaller in the inter-blade-ring center section than in the blade-ring proximate section.
摘要:
Disclosed is a cross flow fan that makes uniform a distribution of wind velocity along an axial direction of the fan at an exit of an air trunk and that lessens chance of separation of an air flow on an inlet side of the fan, and there are thereby provided a cross flow fan that accomplishes a lower input and smaller noise and an air blower and an air conditioner that use the cross flow fan. A cross flow fan being rotatably placed in a horizontally-long air trunk, and including a plurality of annular rings that are substantially parallel to each other and a plurality of blades that are radially interposed between adjacent rings, each having a circular arc cross sectional shape, and a camber angle of the blade is smaller at the ring side than at a center area of the blade between the rings in a longitudinal direction.
摘要:
A diesel particulate defuser (DPD) for collecting particulate matter (PM) in exhaust gas is connected to an exhaust pipe of a diesel engine, and when the amount of PM in the DPD becomes equal to or greater than a predetermined amount, the exhaust gas temperature of the diesel engine is increased by performing exhaust pipe injection and DPD is automatically regenerated. In such an exhaust gas purification system, an exhaust gas temperature during DPD regeneration in automatic regeneration is detected, a difference between the detected exhaust gas temperature and a target regeneration temperature is determined, and in a case where an exhaust pipe injection amount is PID controlled based on the difference, when a transition is made from the traveling automatic regeneration to the idle automatic regeneration conducted during a stop, an integral control term in the PID control is reset to zero to control the exhaust pipe injection amount.
摘要:
An upper suction port is formed in a main-body upper part of an air-conditioning apparatus main body, a suction opening part is formed in a front grill disposed on a main-body front face of the air-conditioning apparatus, a suction opening whose opening is directed upward is formed by consecutively providing an air guide wall inclined downward inside the main body on the upper edge of the suction opening, and the suction opening is located between a part, in the main-body height direction, lower than a straight line passing through a rotation center of an impeller and a closest contact point between the impeller and a front-face heat exchanger and a part, in the main-body height direction, higher than a straight line parallel with the straight line and passing through the impeller and a tongue part of a stabilizer.