利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.02 秒)

    Pharmaceutical containing HIF-1 alpha and HIF-2 alpha expression inhibitor
    1.
    发明授权
    Pharmaceutical containing HIF-1 alpha and HIF-2 alpha expression inhibitor 有权
    含有HIF-1α和HIF-2α表达抑制剂的药物

    公开(公告)号：US08268794B2

    公开(公告)日：2012-09-18

    申请号：US12672473

    申请日：2008-08-05

    申请人： Takeshi Nakajima ,  Emi Nakajima ,  Mitsuyoshi Azuma

    发明人： Takeshi Nakajima ,  Emi Nakajima ,  Mitsuyoshi Azuma

    IPC分类号： A61K48/00 ,  C07H21/02 ,  C07H21/04

    CPC分类号： A61K45/06 ,  A61K31/7088 ,  A61K31/7105 ,  A61K31/713 ,  C12N15/113 ,  C12N15/1136 ,  C12N2310/11 ,  C12N2310/14

    摘要： Provided is a pharmaceutical product exhibiting a high therapeutic effect in the treatment of retinal diseases associated with angiogenesis such as age-related macular degeneration, diabetic retinopathy and the like. A therapeutic agent for a retinal disease, containing a substance specifically inhibiting HIF-1α expression and a substance specifically inhibiting HIF-2α expression. The aforementioned inhibitory substances, which are active ingredients in the therapeutic agent of the present invention, are nucleic acids capable of inducing RNAi, antisense nucleic acids or ribozymes for HIF-1α and HIF-2α, or expression vectors thereof.

    摘要翻译： 本发明提供在治疗与血管生成相关的视网膜疾病如老年性黄斑变性，糖尿病性视网膜病变等中具有高治疗效果的药物。 含有特异性抑制HIF-1α表达的物质的视网膜疾病治疗剂和特异性抑制HIF-2α表达的物质。 作为本发明的治疗剂中的活性成分的上述抑制物质是能够诱导HIF-1α和HIF-2α的RNAi，反义核酸或核酶的核酸或其表达载体。

    PHARMACEUTICAL CONTAINING HIF-1 ALPHA AND HIF-2 ALPHA EXPRESSION INHIBITOR
    2.
    发明申请
    PHARMACEUTICAL CONTAINING HIF-1 ALPHA AND HIF-2 ALPHA EXPRESSION INHIBITOR 有权
    包含HIF-1 ALPHA和HIF-2 ALPHA表达抑制剂的药物

    公开(公告)号：US20110213008A1

    公开(公告)日：2011-09-01

    申请号：US12672473

    申请日：2008-08-05

    申请人： Takeshi Nakajima ,  Emi Nakajima ,  Mitsuyoshi Azuma

    发明人： Takeshi Nakajima ,  Emi Nakajima ,  Mitsuyoshi Azuma

    IPC分类号： A61K31/713 ,  A61P27/02

    CPC分类号： A61K45/06 ,  A61K31/7088 ,  A61K31/7105 ,  A61K31/713 ,  C12N15/113 ,  C12N15/1136 ,  C12N2310/11 ,  C12N2310/14

    摘要： Provided is a pharmaceutical product exhibiting a high therapeutic effect in the treatment of retinal diseases associated with angiogenesis such as age-related macular degeneration, diabetic retinopathy and the like. A therapeutic agent for a retinal disease, containing a substance specifically inhibiting HIF-1α expression and a substance specifically inhibiting HIF-2α expression. The aforementioned inhibitory substances, which are active ingredients in the therapeutic agent of the present invention, are nucleic acids capable of inducing RNAi, antisense nucleic acids or ribozymes for HIF-1α and HIF-2α, or expression vectors thereof.

    摘要翻译： 本发明提供在治疗与血管生成相关的视网膜疾病如老年性黄斑变性，糖尿病性视网膜病变等中具有高治疗效果的药物。 含有特异性抑制HIF-1α表达的物质的视网膜疾病治疗剂和特异性抑制HIF-2α表达的物质。 作为本发明的治疗剂中的活性成分的上述抑制物质是能够诱导HIF-1α和HIF-2α的RNAi，反义核酸或核酶的核酸或其表达载体。

    Transparent conductive film, electronic device, and method for manufacturing electronic device
    3.
    发明授权
    Transparent conductive film, electronic device, and method for manufacturing electronic device 有权
    透明导电膜，电子器件及其制造方法

    公开(公告)号：US09401490B2

    公开(公告)日：2016-07-26

    申请号：US13881952

    申请日：2011-07-20

    申请人： Kunihisa Kato ,  Tsuyoshi Muto ,  Kazue Uemura ,  Emi Nakajima

    发明人： Kunihisa Kato ,  Tsuyoshi Muto ,  Kazue Uemura ,  Emi Nakajima

    IPC分类号： H01L31/00 ,  H01L51/44 ,  H05K1/02 ,  C08J7/04 ,  C09J7/02 ,  C09J9/02 ,  C09J11/08

    CPC分类号： H01L51/442 ,  C08J7/045 ,  C08J7/047 ,  C08J2323/06 ,  C09J7/381 ,  C09J9/02 ,  C09J11/08 ,  C09J2201/602 ,  C09J2203/322 ,  C09J2429/00 ,  C09J2433/00 ,  C09J2479/02 ,  C09J2481/00 ,  H05K1/0274 ,  Y10T156/10

    摘要： The present invention provides a transparent conductive film which is low in terms of surface resistivity and high in terms of transparency.The transparent conductive film according to the present invention includes an adhesive conductive layer in openings of a conductive metal mesh layer provided on at least one surface of a transparent base material, wherein the conductive layer is composed of a conductive adhesive composition containing (A) a water-soluble vinyl polymer, (B) an organic additive, and (C) a conductive organic polymer compound, the organic additive (B) is at least one member selected among water-soluble polyhydric alcohols, water-soluble pyrrolidones, and hydrophilic aprotic solvents, and the conductive organic polymer compound (C) is at least one member selected among polyanilines, polypyrroles, polythiophenes, and derivatives thereof. In addition, the present invention provides an electronic device having the foregoing transparent conductive film and a method for manufacturing an electronic device including forming a photoelectric conversion layer on an anodic layer and sticking the conductive layer of the transparent conductive film and a surface of the photoelectric conversion layer to each other at a temperature at which the foregoing conductive adhesive composition is softened or higher.

    摘要翻译： 本发明提供一种透明导电膜，其表面电阻率低，透明度高。 根据本发明的透明导电膜包括在透明基材的至少一个表面上设置的导电金属网层的开口中的粘合导电层，其中导电层由导电粘合剂组合物构成，该导电粘合剂组合物含有（A） 水溶性乙烯基聚合物，（B）有机添加剂和（C）导电有机高分子化合物，有机添加剂（B）为选自水溶性多元醇，水溶性吡咯烷酮和亲水性非质子性中的至少一种 溶剂，导电性有机高分子化合物（C）为选自聚苯胺，聚吡咯，聚噻吩及其衍生物中的至少1种。 此外，本发明提供一种具有上述透明导电膜的电子器件及其制造方法，该电子器件包括在阳极层上形成光电转换层并粘附透明导电膜的导电层和光电 转化层在上述导电性粘合剂组合物软化或更高温度下彼此接触。

    TRANSPARENT CONDUCTIVE FILM, ELECTRONIC DEVICE, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE
    6.
    发明申请
    TRANSPARENT CONDUCTIVE FILM, ELECTRONIC DEVICE, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE 有权
    透明导电膜，电子器件及制造电子器件的方法

    公开(公告)号：US20130284244A1

    公开(公告)日：2013-10-31

    申请号：US13881952

    申请日：2011-07-20

    申请人： Kunihisa Kato ,  Tsuyoshi Muto ,  Kazue Uemura ,  Emi Nakajima

    发明人： Kunihisa Kato ,  Tsuyoshi Muto ,  Kazue Uemura ,  Emi Nakajima

    IPC分类号： H01L51/44 ,  H05K1/02

    CPC分类号： H01L51/442 ,  C08J7/045 ,  C08J7/047 ,  C08J2323/06 ,  C09J7/381 ,  C09J9/02 ,  C09J11/08 ,  C09J2201/602 ,  C09J2203/322 ,  C09J2429/00 ,  C09J2433/00 ,  C09J2479/02 ,  C09J2481/00 ,  H05K1/0274 ,  Y10T156/10

    摘要： The present invention provides a transparent conductive film which is low in terms of surface resistivity and high in terms of transparency.The transparent conductive film according to the present invention includes an adhesive conductive layer in openings of a conductive metal mesh layer provided on at least one surface of a transparent base material, wherein the conductive layer is composed of a conductive adhesive composition containing (A) a water-soluble vinyl polymer, (B) an organic additive, and (C) a conductive organic polymer compound, the organic additive (B) is at least one member selected among water-soluble polyhydric alcohols, water-soluble pyrrolidones, and hydrophilic aprotic solvents, and the conductive organic polymer compound (C) is at least one member selected among polyanilines, polypyrroles, polythiophenes, and derivatives thereof. In addition, the present invention provides an electronic device having the foregoing transparent conductive film and a method for manufacturing an electronic device including forming a photoelectric conversion layer on an anodic layer and sticking the conductive layer of the transparent conductive film and a surface of the photoelectric conversion layer to each other at a temperature at which the foregoing conductive adhesive composition is softened or higher.

    摘要翻译： 本发明提供一种透明导电膜，其表面电阻率低，透明度高。 根据本发明的透明导电膜包括在透明基材的至少一个表面上设置的导电金属网层的开口中的粘合导电层，其中导电层由导电粘合剂组合物构成，该导电粘合剂组合物含有（A） 水溶性乙烯基聚合物，（B）有机添加剂和（C）导电有机高分子化合物，有机添加剂（B）为选自水溶性多元醇，水溶性吡咯烷酮和亲水性非质子性中的至少一种 溶剂，导电性有机高分子化合物（C）为选自聚苯胺，聚吡咯，聚噻吩及其衍生物中的至少1种。 此外，本发明提供一种具有上述透明导电膜的电子器件及其制造方法，该电子器件包括在阳极层上形成光电转换层并粘附透明导电膜的导电层和光电 转化层在上述导电性粘合剂组合物软化或更高温度下彼此接触。

    ADHESIVE SHEET AND ELECTRONIC DEVICE
    7.
    发明申请
    ADHESIVE SHEET AND ELECTRONIC DEVICE 审中-公开
    粘合片和电子设备

    公开(公告)号：US20130209800A1

    公开(公告)日：2013-08-15

    申请号：US13820837

    申请日：2011-08-18

    申请人： Kazue Uemura ,  Yumiko Amino ,  Yuta Suzuki ,  Yoshitomo Ono ,  Emi Nakajima

    发明人： Kazue Uemura ,  Yumiko Amino ,  Yuta Suzuki ,  Yoshitomo Ono ,  Emi Nakajima

    IPC分类号： C09J7/02 ,  C09J121/00 ,  C09J133/04 ,  C09D183/16

    CPC分类号： C09D183/16 ,  C09J7/29 ,  C09J121/00 ,  C09J133/04 ,  C09J183/16 ,  C09J2203/326 ,  C09J2421/00 ,  C09J2433/00 ,  C09J2483/006 ,  H01L51/5253 ,  H01L51/5256 ,  Y10T428/2848

    摘要： The invention pertains to an adhesive sheet including a base material having thereon at least a gas barrier layer and an adhesive layer, wherein the gas barrier layer is constituted of a material containing at least an oxygen atom and a silicon atom; in a surface layer part of the gas barrier layer, an existing proportion of an oxygen atom is from 60 to 75%, an existing proportion of a nitrogen atom is from 0 to 10%, and an existing proportion of a silicon atom is from 25 to 35% relative to a total existing amount of the oxygen atom, the nitrogen atom, and the silicon atom; and a film density in the surface layer part of the gas barrier layer is from 2.4 to 4.0 g/cm3, and also to an electronic device provided with the subject adhesive sheet as an electronic device member. The invention is able to provide an adhesive sheet with excellent gas barrier properties, resistance to folding and transparency and also an electronic device provided with the subject adhesive sheet as an electronic device member.

    摘要翻译： 本发明涉及一种粘合片，其包括至少具有阻气层和粘合剂层的基材，其中阻气层由至少含有氧原子和硅原子的材料构成; 在阻气层的表层部分中，氧原子的存在比例为60〜75％，氮原子的比例为0〜10％，硅原子的比例为25 至35％，相对于氧原子，氮原子和硅原子的总存在量; 并且阻气层的表层部分中的膜密度为2.4〜4.0g / cm 3，并且还包括设置有作为电子器件构件的被摄体粘合片的电子设备。 本发明能够提供具有优异的阻气性，抗折叠性和透明性的粘合片，以及设置有作为电子器件的目标粘合片的电子装置。