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    Probe and apparatus for determining concentration of light-absorbing materials in living tissue
    1.
    发明授权
    Probe and apparatus for determining concentration of light-absorbing materials in living tissue 有权
    用于测定活体组织中吸光材料浓度的探针和仪器

    公开(公告)号：US06671526B1

    公开(公告)日：2003-12-30

    申请号：US09692044

    申请日：2000-10-20

    申请人： Takuo Aoyagi ,  Masayoshi Fuse ,  Sunao Takeda ,  Cheng-tai Xie ,  Michio Kanemoto

    发明人： Takuo Aoyagi ,  Masayoshi Fuse ,  Sunao Takeda ,  Cheng-tai Xie ,  Michio Kanemoto

    IPC分类号： A61B500

    CPC分类号： A61B5/0059 ,  A61B5/14552

    摘要： A probe 1 includes a light irradiating device 2 and a light receiving device 3, which are oppositely disposed sandwiching living tissue 10. The light irradiating device 2 includes a light source 5 and a scattering plate 6 located in front of the light source 5. The light receiving device 3 includes a photo diode 8 and a light scattering portion. With such an arrangement, of the attenuation of the living tissue 10, non-absorbing attenuation is free from the wavelength. A ratio of absorbing attenuation and a thickness of a blood layer is not affected by a thickness of living tissue. Further, the absorbing attenuation is not dependent on a depth of the blood layer.

    摘要翻译： 探针1包括相对设置的夹持生物体组织10的光照射装置2和光接收装置3.光照射装置2包括位于光源5前方的光源5和散射板6。 光接收装置3包括光电二极管8和光散射部分。 通过这样的布置，对于生物体组织10的衰减，非吸收性衰减不受波长的影响。 吸收衰减的比例和血液层的厚度不受生物体组织的厚度的影响。 此外，吸收衰减不依赖于血液层的深度。

    Method and apparatus for measuring PH of solution
    2.
    发明授权
    Method and apparatus for measuring PH of solution 有权
    测量溶液PH值的方法和装置

    公开(公告)号：US09304088B2

    公开(公告)日：2016-04-05

    申请号：US13400106

    申请日：2012-02-19

    申请人： Mitsuhiro Oura ,  Teruo Okano ,  Tatsuya Shimizu ,  Hirotsugu Kubo ,  Sunao Takeda ,  Shinji Yamamori

    发明人： Mitsuhiro Oura ,  Teruo Okano ,  Tatsuya Shimizu ,  Hirotsugu Kubo ,  Sunao Takeda ,  Shinji Yamamori

    IPC分类号： G01N21/80 ,  G01N31/22 ,  G01N21/31 ,  C12M1/34

    CPC分类号： G01N21/80 ,  C12M41/26 ,  G01N21/3151 ,  G01N31/221 ,  G01N2201/0627 ,  G01N2201/1211

    摘要： A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.

    摘要翻译： 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在所述测量区域的另一侧上接收所发射的光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。

    Cell isolation apparatus
    3.
    发明授权
    Cell isolation apparatus 有权
    细胞分离装置

    公开(公告)号：US08420028B2

    公开(公告)日：2013-04-16

    申请号：US13214774

    申请日：2011-08-22

    申请人： Akane Suzuki ,  Takahiro Shioyama ,  Sunao Takeda

    发明人： Akane Suzuki ,  Takahiro Shioyama ,  Sunao Takeda

    IPC分类号： A61B10/00

    CPC分类号： G01N1/286 ,  G01N1/38 ,  G01N15/14 ,  G01N2001/085 ,  G01N2001/2866

    摘要： A cell isolation apparatus includes: a cylinder member that is inserted into a container into which a reagent is to be introduced; a net which is stretched over the cylinder member; a tissue acquiring unit that is projected from the cylinder member; and a bottom lid portion that is configured by a bottomed pipe in which a first hole that communicates an interior with an exterior is formed, and that is fitted to a bottom portion of the cylinder member in a state where the net and the tissue acquiring unit are accommodated.

    摘要翻译： 细胞隔离装置包括：插入到待引入试剂的容器中的圆筒构件; 在气缸构件上拉伸的网; 组织获取单元，其从所述圆筒构件突出; 以及底盖部，其由形成有与内部连通的第一孔的有底管构成，并且在所述网和所述组织获取单元的状态下嵌合到所述筒构件的底部， 被容纳。

    Pressure measuring method, pressure measuring device, and tonometer
    4.
    发明授权
    Pressure measuring method, pressure measuring device, and tonometer 有权
    压力测量方法，压力测量装置和眼压计

    公开(公告)号：US07713197B2

    公开(公告)日：2010-05-11

    申请号：US11578910

    申请日：2005-03-18

    申请人： Makoto Nakai ,  Sunao Takeda ,  Akihiko Uchiyama ,  Kenji Yanashima ,  Akihiro Fujita ,  Itaru Yoshizawa

    发明人： Makoto Nakai ,  Sunao Takeda ,  Akihiko Uchiyama ,  Kenji Yanashima ,  Akihiro Fujita ,  Itaru Yoshizawa

    IPC分类号： A61B3/16 ,  G01L7/00 ,  G01L9/00 ,  G01L11/00 ,  G01L13/00 ,  G01L15/00 ,  G01L17/00 ,  G01L19/00 ,  G01L21/00 ,  G01L21/02

    CPC分类号： G01L9/0022 ,  A61B3/16 ,  A61B5/0051 ,  G01L9/008

    摘要： A tonometry device includes a contact device for contacting the object, means for vibrating the contact device and the object, means for applying a voltage to the vibration means, means for measuring a current flowing through the vibration means, and an information processing means. The information processing means determines two resonance points of the device and the measured object by measuring current through the system at a plurality of vibrational frequencies. The information processing means then determines the internal pressure of the object by determining that a first pressure is higher than a second pressure by determining that the first pressure has a lower measured current than the second pressure at frequencies outside of the range of frequencies between the resonance points, and that the first pressure has a higher measured current than the second pressure at frequencies within the range of frequencies between the resonance points.

    摘要翻译： 测压装置包括用于接触物体的接触装置，用于振动接触装置和物体的装置，用于向振动装置施加电压的装置，用于测量流过振动装置的电流的装置，以及信息处理装置。 信息处理装置通过以多个振动频率测量通过系统的电流来确定装置和被测物体的两个共振点。 信息处理装置然后通过确定第一压力高于第二压力来确定对象的内部压力，通过确定第一压力具有比谐振频率范围之外的频率处的第二压力低的测量电流 并且第一压力在谐振点之间的频率范围内的频率处具有比第二压力更高的测量电流。

    5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient
    6.
    发明授权
    5-aminoquinolone carboxylic acid derivative and antibacterial agent containing the same as active ingredient 失效
    5-氨基喹诺酮羧酸衍生物和含有活性成分的抗菌剂

    公开(公告)号：US5430028A

    公开(公告)日：1995-07-04

    申请号：US185898

    申请日：1994-01-26

    申请人： Terumitsu Kaihoh ,  Sunao Takeda ,  Fujiko Konno ,  Akihiro Shibata ,  Masaru Matsumoto ,  Takemitsu Asaoka ,  Hideaki Matsuda ,  Tadayuki Kuraishi

    发明人： Terumitsu Kaihoh ,  Sunao Takeda ,  Fujiko Konno ,  Akihiro Shibata ,  Masaru Matsumoto ,  Takemitsu Asaoka ,  Hideaki Matsuda ,  Tadayuki Kuraishi

    IPC分类号： A61K31/47 ,  A61K31/495 ,  C07D215/56 ,  C07D401/04 ,  A61K31/55 ,  A61K31/505 ,  C07D243/00 ,  C07D243/08

    CPC分类号： C07D215/56 ,  A61K31/47 ,  A61K31/495 ,  C07D401/04

    摘要： A 5-aminoquinolone carboxylic acid derivative represented by the following general formula (1): ##STR1## wherein R.sup.1 means a hydrogen atom, an amino group, a linear or branched alkyl group having 1-5 carbon atoms and an alkylamino group containing a linear or branched alkyl group having 1-5 carbon atoms, R.sup.2 denotes a hydrogen atom or a linear or branched alkyl group having 1-5 carbon atoms, X stands for a halogen atom, Y means CH.sub.2, NH, CHR.sup.3 NR.sup.3, (R.sup.3 denoting a linear or branched alkyl group having 1-5 carbon atoms) or an oxygen atom, and Z stands for an oxygen atom or 2 hydrogen atoms, or a salt thereof, and an antibacterial agent containing such a derivative or salt as an active ingredient.The derivative or salt thereof exhibits strong anti-bacterial activities against Grampositive bacteria including tolerant bacteria, and is satisfactorily absorbed in a living body.

    摘要翻译： PCT No.PCT / JP93 / 00694 Sec。 371日期1994年1月26日 102（e）日期1994年1月26日PCT提交1993年5月25日PCT公布。 出版物WO93 / 24460 PCT 日期：1993年12月9日，下列通式（1）表示的5-氨基喹诺酮羧酸衍生物：其中R 1表示氢原子，氨基，直链或支链烷基， 5个碳原子和含有1-5个碳原子的直链或支链烷基的烷基氨基，R2表示氢原子或具有1-5个碳原子的直链或支链烷基，X表示卤素原子，Y表示CH2 ，NH，CHR 3 NR 3，（R3表示具有1-5个碳原子的直链或支链烷基）或氧原子，Z表示氧原子或2个氢原子，或其盐，以及含有这些的抗菌剂 衍生物或盐作为活性成分。 其衍生物或盐对包括耐受性细菌的细菌性细菌表现出强的抗菌活性，并且令人满意地吸收在生物体内。

    METHOD AND APPARATUS FOR MEASURING PH OF SOLUTION
    7.
    发明申请
    METHOD AND APPARATUS FOR MEASURING PH OF SOLUTION 有权
    用于测量溶液PH值的方法和装置

    公开(公告)号：US20120214250A1

    公开(公告)日：2012-08-23

    申请号：US13400106

    申请日：2012-02-19

    申请人： Mitsuhiro Oura ,  Teruo Okano ,  Tatsuya Shimizu ,  Hirotsugu Kubo ,  Sunao Takeda ,  Shinji Yamamori

    发明人： Mitsuhiro Oura ,  Teruo Okano ,  Tatsuya Shimizu ,  Hirotsugu Kubo ,  Sunao Takeda ,  Shinji Yamamori

    IPC分类号： G01N21/59

    CPC分类号： G01N21/80 ,  C12M41/26 ,  G01N21/3151 ,  G01N31/221 ,  G01N2201/0627 ,  G01N2201/1211

    摘要： A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances ; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.

    摘要翻译： 测量溶液的pH的方法包括：在测量区域中的溶液脉动的同时，从混合有指示剂的溶液的测量区域的一侧发射两个波长的光束; 在所述测量区域中的所述溶液脉动的同时，在测量区域的另一侧上接收发射光束的透射光束和反射光束中的至少一个; 基于所接收的所述透射光束和所述反射光束中的至少一个，获得所述两个波长的吸光度; 从所获得的吸光度获得吸光度比; 并且基于所获得的吸光度比和预先存储的吸光度比/ pH值对应数据库来计算溶液的pH值。