利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

8 条记录 (耗时 0.023 秒)

    Two-chamber dual-pore device
    1.
    发明授权
    Two-chamber dual-pore device 有权

    公开(公告)号：US11054390B2

    公开(公告)日：2021-07-06

    申请号：US16443025

    申请日：2019-06-17

    申请人： The Regents of the University of California ,  Brigham Young University

    发明人： William Dunbar ,  Holger Schmidt ,  Aaron Hawkins

    IPC分类号： G01N27/327 ,  G01N27/447 ,  G01N33/487 ,  C12Q1/6869 ,  B82Y15/00

    摘要： Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.

    Two-Chamber Dual-Pore Device
    2.
    发明申请
    Two-Chamber Dual-Pore Device 审中-公开

    公开(公告)号：US20200150084A1

    公开(公告)日：2020-05-14

    申请号：US16443025

    申请日：2019-06-17

    申请人： The Regents of the University of California ,  Brigham Young University

    发明人： William Dunbar ,  Holger Schmidt ,  Aaron Hawkins

    IPC分类号： G01N27/447 ,  C12Q1/6869 ,  G01N33/487

    摘要： Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.

    TWO-CHAMBER DUAL-PORE DEVICE
    4.
    发明申请
    TWO-CHAMBER DUAL-PORE DEVICE 审中-公开

    公开(公告)号：US20170269034A1

    公开(公告)日：2017-09-21

    申请号：US15606726

    申请日：2017-05-26

    申请人： The Regents of the University of California ,  Brigham Young University

    发明人： William Dunbar ,  Holger Schmidt ,  Aaron Hawkins

    IPC分类号： G01N27/447 ,  C12Q1/68 ,  G01N33/487 ,  B82Y15/00

    CPC分类号： G01N27/44791 ,  B82Y15/00 ,  C12Q1/6869 ,  G01N33/48721 ,  C12Q2565/631

    摘要： Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.

    Two-chamber dual-pore device
    5.
    发明授权
    Two-chamber dual-pore device 有权

    公开(公告)号：US09696277B2

    公开(公告)日：2017-07-04

    申请号：US14358001

    申请日：2012-11-13

    申请人： The Regents of the University of California ,  Brigham Young University

    发明人： William Dunbar ,  Holger Schmidt ,  Aaron Hawkins

    IPC分类号： G01N27/327 ,  G01N27/447 ,  G01N33/487 ,  C12Q1/68 ,  B82Y15/00

    CPC分类号： G01N27/44791 ,  B82Y15/00 ,  C12Q1/6869 ,  G01N33/48721 ,  C12Q2565/631

    摘要： Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.

    Two-Chamber Dual-Pore Device
    8.
    发明申请
    Two-Chamber Dual-Pore Device 有权
    双室双孔设备

    公开(公告)号：US20140318964A1

    公开(公告)日：2014-10-30

    申请号：US14358001

    申请日：2012-11-13

    申请人： The Regents of the University of California ,  Brigham Young University

    发明人： William Dunbar ,  Holger Schmidt ,  Aaron Hawkins

    IPC分类号： G01N27/447 ,  G01N33/487

    CPC分类号： G01N27/44791 ,  B82Y15/00 ,  C12Q1/6869 ,  G01N33/48721 ,  C12Q2565/631

    摘要： Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.

    摘要翻译： 提供一种装置，其包括通过围绕通道的多个层限定的通道，所述通道连接由所述多个层分隔的第一和第二室，其中所述多个层包括第一层，第二层; 以及设置在所述第一层和第二层之间的导电中间层，其中所述沟道包括（a）由所述第一层限定的第一区域（表示为入口），其直径为约0.5nm至约100nm，以及（b） 由第二层限定的第二区域，表示为出口，其中入口和出口彼此间隔约10nm至约1000nm，并且其中第一和第二室和中间层连接到电源。 还提供了制备和使用该装置的方法，特别是用于核酸测序。