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公开(公告)号：US12071455B2
公开(公告)日：2024-08-27
申请号：US17458131
申请日：2021-08-26
IPC分类号： C07K14/195 , B01D15/36 , B01D15/38 , C07K1/22 , C07K14/315 , C12N15/62
CPC分类号： C07K14/195 , B01D15/363 , B01D15/3804 , C07K1/22 , C07K14/315 , C12N15/62 , C07K2319/70
摘要： The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.
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公开(公告)号：US20210395314A1
公开(公告)日：2021-12-23
申请号：US17458131
申请日：2021-08-26
IPC分类号： C07K14/195 , C12N15/62 , C07K1/22 , B01D15/36 , B01D15/38 , C07K14/315
摘要： The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.
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公开(公告)号：US11130788B2
公开(公告)日：2021-09-28
申请号：US16412133
申请日：2019-05-14
IPC分类号： C07K1/00 , C07K14/195 , C12N15/62 , C07K1/22 , B01D15/36 , B01D15/38 , C07K14/315
摘要： The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.
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公开(公告)号：US20210206816A1
公开(公告)日：2021-07-08
申请号：US16670125
申请日：2019-10-31
IPC分类号： C07K14/405 , C10L1/02 , C12N1/32 , C12N9/14 , C12P5/00 , C12N15/82 , C12P7/16 , C12P7/06 , C12P7/24 , C07K14/195
摘要： A fusion chimeric protein is described herein that can assemble a functional carboxysome core, which is able to fix carbon by taking atmospheric carbon dioxide and converting it into useful carbon-containing compounds such as 3-phosphoglycerate (3-PGA).
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公开(公告)号：US20180216117A1
公开(公告)日：2018-08-02
申请号：US15851382
申请日：2017-12-21
IPC分类号： C12N15/52 , C07K14/195 , C12N15/113 , C12N15/74 , C12N15/67 , C12N15/65
CPC分类号： C12N15/52 , C07K14/195 , C07K2319/01 , C07K2319/735 , C12N15/113 , C12N15/65 , C12N15/67 , C12N15/74
摘要： Described herein are bacterial microcompartments shell proteins modified to stably incorporate iron-sulfur clusters. Such bacterial microcompartments shell proteins exhibit redox cycling and confer electron transfer functionality to bacterial microcompartment shells.
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公开(公告)号：US11673923B2
公开(公告)日：2023-06-13
申请号：US16670125
申请日：2019-10-31
IPC分类号： C12N9/14 , C07K14/405 , C10L1/02 , C12N1/32 , C12P5/00 , C12N15/82 , C12P7/16 , C12P7/06 , C12P7/24 , C07K14/195 , C12P39/00
CPC分类号： C07K14/405 , C07K14/195 , C10L1/02 , C12N1/32 , C12N9/14 , C12N15/8261 , C12P5/007 , C12P7/065 , C12P7/16 , C12P7/24 , C07K2319/00 , C12P39/00 , Y02A40/146 , Y02E50/10 , Y02P60/20
摘要： A fusion chimeric protein is described herein that can assemble a functional carboxysome core, which is able to fix carbon by taking atmospheric carbon dioxide and converting it into useful carbon-containing compounds such as 3-phosphoglycerate (3-PGA).
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公开(公告)号：US10479999B2
公开(公告)日：2019-11-19
申请号：US15851382
申请日：2017-12-21
IPC分类号： C12N15/52 , C12N15/113 , C12N15/74 , C12N15/67 , C12N15/65 , C07K14/195
摘要： Described herein are bacterial microcompartments shell proteins modified to stably incorporate iron-sulfur clusters. Such bacterial microcompartments shell proteins exhibit redox cycling and confer electron transfer functionality to bacterial microcompartment shells.
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公开(公告)号：US20180057546A1
公开(公告)日：2018-03-01
申请号：US15685742
申请日：2017-08-24
IPC分类号： C07K14/405 , C10L1/02 , C12N1/32 , C12N9/14 , C12P5/00
CPC分类号： C07K14/405 , C07K14/195 , C07K2319/00 , C10L1/02 , C12N1/32 , C12N9/14 , C12N15/8261 , C12P5/007 , C12P7/065 , C12P7/16 , C12P7/24 , C12P39/00 , Y02A40/146 , Y02E50/10 , Y02E50/17 , Y02P60/247
摘要： A fusion chimeric protein is described herein that can assemble a functional carboxysome core, which is able to fix carbon by taking atmospheric carbon dioxide and converting it into useful caron-containing compounds such as 3-phosphoglycerate (3-PGA).
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公开(公告)号：US12054520B2
公开(公告)日：2024-08-06
申请号：US17531183
申请日：2021-11-19
IPC分类号： C07K14/195 , C12N15/70
CPC分类号： C07K14/195 , C12N15/70 , C07K2319/00
摘要： Described herein are constructs, compositions and methods for precise in vivo imaging of the structures and dynamics of protein-based scaffolds with and without their designated cargos.
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公开(公告)号：US20220162268A1
公开(公告)日：2022-05-26
申请号：US17531183
申请日：2021-11-19
IPC分类号： C07K14/195 , C12N15/70
摘要： Described herein are constructs, compositions and methods for precise in vivo imaging of the structures and dynamics of protein-based scaffolds with and without their designated cargos.
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