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    Sucrose-6-phosphate phosphatase as target for herbicides
    1.
    发明授权
    Sucrose-6-phosphate phosphatase as target for herbicides 失效
    蔗糖-6-磷酸酯酶作为除草剂的靶标

    公开(公告)号：US07374899B2

    公开(公告)日：2008-05-20

    申请号：US10522096

    申请日：2003-07-16

    申请人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Börnke ,  Shuai Chen

    发明人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Börnke ,  Shuai Chen

    IPC分类号： C12Q1/42

    CPC分类号： C12N9/16 ,  C12N15/8274

    摘要： The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.

    摘要翻译： 本发明涉及具有蔗糖-6-磷酸磷酸酶的生物学活性的多肽的用途，如果不存在，则会导致生长迟缓症状和褪绿叶，并由核酸序列SEQ ID NO：1编码 ，SEQ ID NO：3，SEQ ID NO：5或功能等同物为SEQ ID NO：1，SEQ ID NO：3或SEQ ID NO：5作为除草剂的靶标。 此外，本发明涉及上述多肽在鉴定抑制蔗糖-6-磷酸磷酸酶的除草或生长调节化合物的方法中的用途。 此外，本发明涉及通过该方法鉴定的这些化合物作为除草剂或生长调节剂的用途。

    Serine hydroxymethyltransferase as a target for herbicides
    3.
    发明授权
    Serine hydroxymethyltransferase as a target for herbicides 失效
    丝氨酸羟甲基转移酶作为除草剂的靶标

    公开(公告)号：US07319013B2

    公开(公告)日：2008-01-15

    申请号：US10507989

    申请日：2003-03-13

    申请人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    发明人： Uwe Sonnewald ,  Frederik Börnke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    IPC分类号： C12Q1/48 ,  C12N9/10 ,  C12N5/04 ,  C12N5/14 ,  C07H21/04

    CPC分类号： C12N9/1014 ,  C12N15/8274

    摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

    摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。

    Saccarose-6-phosphate phosphatase as a target for herbicides
    4.
    发明申请
    Saccarose-6-phosphate phosphatase as a target for herbicides 失效
    Saccarose-6-磷酸磷酸酶作为除草剂的靶标

    公开(公告)号：US20060035786A1

    公开(公告)日：2006-02-16

    申请号：US10522096

    申请日：2003-07-16

    申请人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Bornke ,  Shuai Chen

    发明人： Thomas Ehrhardt ,  Uwe Sonnewald ,  Frederik Bornke ,  Shuai Chen

    IPC分类号： A01N25/00 ,  C12Q1/68 ,  C12Q1/42 ,  C12P21/06 ,  C12N9/16 ,  C40B30/04

    CPC分类号： C12N9/16 ,  C12N15/8274

    摘要： The present invention relates to the use of a polypeptide with the biological activity of a sucrose-6-phosphate phosphatase which, if not present, brings about growth retardation symptoms and chlorotic leaves and which is encoded by the nucleic acid sequences SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5 or by a functional equivalent of SEQ ID NO:1, SEQ ID NO:3 or SEQ ID NO:5 as target for herbicides. Moreover, the present invention relates to the use of the abovementioned polypeptides in a method for identifying herbicidal or growth-regulatory compounds which inhibit sucrose-6-phosphate phosphatase. Moreover, the invention relates to the use of these compounds which have been identified via the method as herbicides or growth regulators.

    摘要翻译： 本发明涉及具有蔗糖-6-磷酸磷酸酶的生物学活性的多肽的用途，如果不存在，则会导致生长迟缓症状和褪绿叶，并由核酸序列SEQ ID NO：1编码 ，SEQ ID NO：3，SEQ ID NO：5或功能等同物为SEQ ID NO：1，SEQ ID NO：3或SEQ ID NO：5作为除草剂的靶标。 此外，本发明涉及上述多肽在鉴定抑制蔗糖-6-磷酸磷酸酶的除草或生长调节化合物的方法中的用途。 此外，本发明涉及通过该方法鉴定的这些化合物作为除草剂或生长调节剂的用途。

    Nucleic acid encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase
    10.
    发明授权
    Nucleic acid encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase 失效
    编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸

    公开(公告)号：US07662603B2

    公开(公告)日：2010-02-16

    申请号：US11949874

    申请日：2007-12-04

    申请人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    发明人： Uwe Sonnewald ,  Frederik Boernke ,  Kirsten Deist ,  Marc Stitt Nigel ,  Wolfgang Lein ,  Thomas Ehrhardt ,  Andreas Reindl ,  Ralf-Michael Schmidt ,  Annette Freund

    IPC分类号： C12N9/00 ,  C12N9/10 ,  C12N1/20 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12N9/1014 ,  C12N15/8274

    摘要： The present invention relates to serine hydroxymethyltransferase (E.C. 2.1.2.1) as novel target for herbicides, and to nucleic acid sequences encoding a polypeptide with the biological activity of a serine hydroxymethyltransferase, which, when not present, bring about growth retardation symptoms and chlorotic leaves, comprising the nucleic acid sequence SEQ ID No:3, and functional equivalents of the abovementioned nucleic acid sequence or the nucleic acid sequence SEQ ID NO:7 and functional equivalents of the abovementioned nucleic acid sequence. Moreover, the present invention relates to the use of the abovementioned nucleic acid sequences, of functional analogs of the SEQ ID NO:3 or SEQ ID NO:7 or of polypeptides encoded by one of the abovementioned nucleic acid sequences in a method for identifying herbicidally active compounds which inhibit serine hydroxymethyltransferases, and to the use of these compounds which have been identified by the method as herbicides.

    摘要翻译： 本发明涉及丝氨酸羟甲基转移酶（EC 2.1.2.1）作为除草剂的新靶标，以及编码具有丝氨酸羟甲基转移酶生物活性的多肽的核酸序列，当不存在时，其产生生长迟缓症状和褪绿叶 包括核酸序列SEQ ID No：3和上述核酸序列或核酸序列SEQ ID NO：7的功能等同物和上述核酸序列的功能等同物。 此外，本发明涉及上述核酸序列，SEQ ID NO：3或SEQ ID NO：7的功能类似物或由上述核酸序列之一编码的多肽在除草方法中的用途 抑制丝氨酸羟甲基转移酶的活性化合物，以及通过该方法鉴定的这些化合物作为除草剂的用途。