Soothing Agent and Food for Treating Fatigue
    1.
    发明申请
    Soothing Agent and Food for Treating Fatigue 审中-公开
    舒缓剂和食物治疗疲劳

    公开(公告)号:US20080009440A1

    公开(公告)日:2008-01-10

    申请号:US10589073

    申请日:2005-02-07

    IPC分类号: A61K38/16 A23L1/00 A61P43/00

    摘要: It is an objective of the present invention to provide a soothing agent and a food for treating fatigue whereby: physical strength can be quickly restored from exhaustion (a state with lowered spontaneous motility), such as after exercise or exhausting labor or upon awakening in the early morning; physical strength decline can be prevented; and physical strength can be maintained.In accordance with the present invention, a soothing agent and/or a revitalizing agent containing protein hydrolysates obtained by degrading substrate protein via germinated soybean cotyledon-derived thiol protease and/or microorganism-derived serine protease are provided.

    摘要翻译: 本发明的目的是提供一种舒缓剂和用于治疗疲劳的食物,其中:能够迅速地恢复身体强度(例如在运动或排气劳动之后,或在唤醒中, 清晨; 体力下降可以预防; 并保持体力。 根据本发明,提供了通过由发芽大豆子叶来源的硫羟蛋白酶和/或微生物来源的丝氨酸蛋白酶降解底物蛋白而获得的含有蛋白质水解物的舒缓剂和/或活化剂。

    Method of improving taste and/or flavour of foods and beverages
    2.
    发明授权
    Method of improving taste and/or flavour of foods and beverages 失效
    改善食品和饮料味道和/或风味的方法

    公开(公告)号:US07255888B2

    公开(公告)日:2007-08-14

    申请号:US11287235

    申请日:2005-11-28

    摘要: The present invention discloses a method for producing foods and/or beverage having improved taste and/or flavour, comprising reacting a microbial aminopeptidase on a protein material optionally under the co-existence of a protease, wherein said aminopeptidase has the properties of: (a) having an activity of catalyzing the reaction of specifically releasing a glutamic acid and an aspartic acid from the N-terminal of a peptide and/or a protein; (b) having 50% or more activity at pH6.0-9.0 as compared with the activity at the optimum pH; (c) having 40% or more activity after heating at 25-60° C., pH7.5 for 30 minutes as compared with the activity of the non-heated enzyme; (d) having a molecular weight of about 40-60 kD as measured by SDS-PAGE and about 300-480 kD as measured by native-PAGE; (e) having a hydrolyzing activity of the aminopeptidase toward Glu-Glu dipeptide is 5 U/mg or more, preferably 10 U/mg or more.

    摘要翻译: 本发明公开了一种生产具有改善的味道和/或风味的食品和/或饮料的方法,包括任选地在蛋白酶共存下使蛋白质材料上的微生物氨基肽酶反应,其中所述氨基肽酶具有以下性质:(a )具有催化从肽和/或蛋白质的N末端特异性释放谷氨酸和天冬氨酸的反应的活性; (b)与最适pH下的活性相比,在pH6.0-9.0时具有50%以上的活性; (c)与未加热的酶的活性相比,在25-60℃,pH7.5加热30分钟后具有40%或更高的活性; (d)通过SDS-PAGE测量的分子量为约40-60kD,通过天然PAGE测量为约300-480kD; (e)氨基肽酶对Glu-Glu二肽的水解活性为5U / mg以上,优选为10U / mg以上。

    Method of improving taste and/or flavour of foods and beverages
    3.
    发明申请
    Method of improving taste and/or flavour of foods and beverages 失效
    改善食品和饮料味道和/或风味的方法

    公开(公告)号:US20060068056A1

    公开(公告)日:2006-03-30

    申请号:US11287235

    申请日:2005-11-28

    IPC分类号: A23K1/18 C12N9/52

    摘要: The present invention discloses a method for producing foods and/or beverage having improved taste and/or flavour, comprising reacting a microbial aminopeptidase on a protein material optionally under the co-existence of a protease, wherein said aminopeptidase has the properties of: (a) having an activity of catalyzing the reaction of specifically releasing a glutamic acid and an aspartic acid from the N-terminal of a peptide and/or a protein; (b) having 50% or more activity at pH6.0-9.0 as compared with the activity at the optimum pH; (c) having 40% or more activity after heating at 25-60° C., pH7.5 for 30 minutes as compared with the activity of the non-heated enzyme; (d) having a molecular weight of about 40-60 kD as measured by SDS-PAGE and about 300-480 kD as measured by native-PAGE; (e) having a hydrolyzing activity of the aminopeptidase toward Glu-Glu dipeptide is 5 U/mg or more, preferably 10 U/mg or more.

    摘要翻译: 本发明公开了一种生产具有改善的味道和/或风味的食品和/或饮料的方法,包括任选地在蛋白酶共存下使蛋白质材料上的微生物氨基肽酶反应,其中所述氨基肽酶具有以下性质:(a )具有催化从肽和/或蛋白质的N末端特异性释放谷氨酸和天冬氨酸的反应的活性; (b)与最适pH下的活性相比,在pH6.0-9.0时具有50%以上的活性; (c)与未加热的酶的活性相比,在25-60℃,pH7.5加热30分钟后具有40%或更高的活性; (d)通过SDS-PAGE测量的分子量为约40-60kD,通过天然PAGE测量为约300-480kD; (e)氨基肽酶对Glu-Glu二肽的水解活性为5U / mg以上,优选为10U / mg以上。

    Immunostimulating agent
    8.
    发明授权
    Immunostimulating agent 有权
    免疫刺激剂

    公开(公告)号:US08454978B2

    公开(公告)日:2013-06-04

    申请号:US12899045

    申请日:2010-10-06

    IPC分类号: A61K38/05

    摘要: An immunostimulating agent, which can stimulate immunity effectively, is described. The immunostimulating agent contains an active ingredient including a calcium receptor activator such as γ-Glu-X-Gly [wherein X represents an amino acid or a derivative thereof other than Cys], γ-Glu-Val-Y [wherein Y represents an amino acid or a derivative thereof], γ-Glu-Ala, γ-Glu-Gly, γ-Glu-Met, γ-Glu-Thr, γ-Glu-Val, γ-Glu-Orn, Asp-Gly, Cys-Gly, Cys-Met, Glu-Cys, Gly-Cys, Leu-Asp, γ-Glu-Met(O), γ-Glu-γ-Glu-Val, γ-Glu-Val-NH2, γ-Glu-Val-ol, γ-Glu-Ser, γ-Glu-Tau, γ-Glu-Cys(S-Me)(O), γ-Glu-Leu, γ-Glu-Ile, γ-Glu-t-Leu, γ-Glu-Cys(S-Me), a cation having a valency of 2 or more, protamine, polylysine, spermine, spermidine, putrescine, cinacalcet, a cinacalcet analogue compound, and a salt of any one of the aforementioned components.

    摘要翻译: 描述了可以有效地刺激免疫的免疫刺激剂。 免疫刺激剂含有活性成分,包括钙受体激活剂如γ-Glu-X-Gly [其中X表示除Cys之外的氨基酸或其衍生物],γ-Glu-Val-Y [其中Y表示氨基 酸或其衍生物],γ-Glu-Ala,γ-Glu-Gly,γ-Glu-Met,γ-Glu-Thr,γ-Glu-Val,γ-Glu-Orn,Asp-Gly,Cys-Gly ,Cys-Met,Glu-Cys,Gly-Cys,Leu-Asp,γ-Glu-Met(O),γ-Glu-γ-Glu-Val,γ-Glu-Val-NH2, (S-Me)(O),γ-Glu-Leu,γ-Glu-Ile,γ-Glu-t-Leu,γ-Glu-Leu, Glu-Cys(S-Me),2价以上的阳离子,鱼精蛋白,聚赖氨酸,精胺,亚精胺,腐胺,西那卡塞,西那卡塞类似物化合物和上述成分中的任一种的盐。