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1.发明申请公开(公告)号：US20110059145A1
公开(公告)日：2011-03-10
申请号：US12991036
申请日：2009-04-30
申请人： Toshiaki Kubo , Tomoko Tashiro , Hisahiro Mori , Jun Arakawa
发明人： Toshiaki Kubo , Tomoko Tashiro , Hisahiro Mori , Jun Arakawa
CPC分类号： A61K31/164 , A61K8/0241 , A61K8/65 , A61K8/68 , A61K8/735 , A61K31/715 , A61K31/728 , A61K38/17 , A61K2800/413 , A61K2800/624 , A61Q19/00
摘要： A topical composition for external use comprising: a ceramide analogue-containing particle having a particle diameter of 0.001 μm to 0.2 μm; and a water-soluble polymer. It is preferable that, further, an oil component different from the ceramide analogue is contained in an amount of 20 parts by mass or less relative to 1 part by mass of the ceramide analogue-containing particle, and the ceramide analogue-containing particle is present in the oil component.
摘要翻译： 一种外用局部用组合物，其特征在于：含有粒径为0.001〜0.2μm的含有神经酰胺类似物的颗粒; 和水溶性聚合物。 此外，相对于含有神经酰胺类似物的颗粒1质量份，含有不同于神经酰胺类似物的油成分的含量优选为20质量份以下，含有神经酰胺类似物的颗粒存在 在油分中。
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公开(公告)号：US20110076311A1
公开(公告)日：2011-03-31
申请号：US12994769
申请日：2009-05-29
申请人： Shinichiro Serizawa , Hisahiro Mori , Jun Arakawa , Tomoko Tashiro , Toshiaki Kubo , Yoshisada Nakamura , Tomohide Ueyama
发明人： Shinichiro Serizawa , Hisahiro Mori , Jun Arakawa , Tomoko Tashiro , Toshiaki Kubo , Yoshisada Nakamura , Tomohide Ueyama
IPC分类号： A61K8/02 , A61K9/14 , A61K47/44 , A61P17/00 , A61P29/00 , A61Q1/04 , A61Q1/02 , A61Q5/02 , A61Q15/00 , A61Q17/04
CPC分类号： A61K31/164 , A23L33/12 , A23V2002/00 , A61K8/06 , A61K8/062 , A61K8/375 , A61K8/39 , A61K8/68 , A61K2800/413 , A61K2800/592 , A61K2800/92 , A61Q1/02 , A61Q1/06 , A61Q17/04 , A23V2200/318 , A23V2200/254
摘要： A ceramide dispersion, which includes at least: natural-ceramide-containing particles that are dispersed in an aqueous phase as an oil-phase component; and at least one surfactant, wherein the natural-ceramide-containing particles contain one or more natural ceramides in an amount of 50% by mass or higher with respect to the total mass of the oil components contained in an oil phase, and have a volume average particle diameter of from 0.5 nm to 100 nm; and the ceramide dispersion contains, in the at least one surfactant, at least one polyglycerin fatty acid ester having an HLB of from 10 to 16.
摘要翻译： 神经酰胺分散体，其至少包含：作为油相成分分散在水相中的含天然神经酰胺的颗粒; 和至少一种表面活性剂，其中所述含天然神经酰胺的颗粒含有相对于油相中所含的油成分的总质量为50质量％以上的一种或多种天然神经酰胺，并且具有体积 平均粒径为0.5nm至100nm; 并且所述神经酰胺分散体在所述至少一种表面活性剂中含有至少一种HLB为10至16的聚甘油脂肪酸酯。
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公开(公告)号：US08642052B2
公开(公告)日：2014-02-04
申请号：US13121354
申请日：2009-09-30
IPC分类号： A61K9/00
CPC分类号： A61K8/68 , A61K8/06 , A61K8/062 , A61K8/361 , A61K9/0014 , A61K9/1075 , A61K47/18 , A61K2800/21 , A61Q1/02 , A61Q1/06 , A61Q17/04 , A61Q19/00
摘要： The present invention provides a ceramide dispersion which includes (1) ceramide-containing particles which contains a ceramide, which are dispersed in an aqueous phase as an oil-phase component, and which have a volume average particle diameter from 1 nm to 100 nm; and (2) a fatty acid component which is at least one of a fatty acid having a melting temperature not higher than 30° C. or a fatty acid salt; the amount of nonionic surfactant being 0 or not more than 0.1 times the total mass of the ceramide; the amount of an ionic surfactant other than the fatty acid component being 0 or less than 0.05 times the total mass of the ceramide; and the pH being from 6 to 8.
摘要翻译： 本发明提供了一种神经酰胺分散体，其包含（1）含有神经酰胺的含有神经酰胺的颗粒，其分散在水相中作为油相成分，体积平均粒径为1nm〜100nm; 和（2）脂肪酸成分，其为熔解温度不高于30℃的脂肪酸或脂肪酸盐中的至少一种; 非离子表面活性剂的量为0或不超过神经酰胺总质量的0.1倍; 除了脂肪酸成分以外的离子表面活性剂的量为0或小于神经酰胺总质量的0.05倍; pH为6〜8。
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公开(公告)号：US20110182999A1
公开(公告)日：2011-07-28
申请号：US13121354
申请日：2009-09-30
CPC分类号： A61K8/68 , A61K8/06 , A61K8/062 , A61K8/361 , A61K9/0014 , A61K9/1075 , A61K47/18 , A61K2800/21 , A61Q1/02 , A61Q1/06 , A61Q17/04 , A61Q19/00
摘要： The present invention provides a ceramide dispersion which includes (1) ceramide-containing particles which contains a ceramide, which are dispersed in an aqueous phase as an oil-phase component, and which have a volume average particle diameter from 1 nm to 100 nm; and (2) a fatty acid component which is at least one of a fatty acid having a melting temperature not higher than 30° C. or a fatty acid salt; the amount of nonionic surfactant being 0 or not more than 0.1 times the total mass of the ceramide; the amount of an ionic surfactant other than the fatty acid component being 0 or less than 0.05 times the total mass of the ceramide; and the pH being from 6 to 8.
摘要翻译： 本发明提供了一种神经酰胺分散体，其包含（1）含有神经酰胺的含有神经酰胺的颗粒，其分散在水相中作为油相成分，体积平均粒径为1nm〜100nm; 和（2）脂肪酸成分，其为熔解温度不高于30℃的脂肪酸或脂肪酸盐中的至少一种; 非离子表面活性剂的量为0或不超过神经酰胺总质量的0.1倍; 除了脂肪酸成分以外的离子表面活性剂的量为0或小于神经酰胺总质量的0.05倍; pH为6〜8。
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公开(公告)号：US20130035395A1
公开(公告)日：2013-02-07
申请号：US13639561
申请日：2011-03-24
摘要： A water-based cosmetic that includes: (A) ceramidic compound-containing particles that include a ceramidic compound and that are dispersed as an oil phase in an aqueous phase; (B) a fatty acid component composed of at least one selected from the group consisting of fatty acids and fatty acid salts; and (C) a polyhydric alcohol component that includes a first polyhydric alcohol having an IOB of 2.2 or more and a total content in the composition of from 3% by mass to 20% by mass, and a second polyhydric alcohol having an IOB of 2.0 or less and a total content in the composition of 0% by mass or not more than 3% by mass, wherein a total content of surfactant in the composition is 0% by mass or not more than 1% by mass, and a total mass of ceramidic compound in the composition is at least 3.0 times a total mass of the fatty acid component in the composition.
摘要翻译： 一种水性化妆品，其包含：（A）含有神经酰胺化合物的含有神经酰胺化合物的颗粒，其在水相中以油相分散; （B）由选自脂肪酸和脂肪酸盐中的至少一种组成的脂肪酸组分; 和（C）多元醇组分，其包含IOB为2.2或更高的第一多元醇和组合物的总含量为3质量％至20质量％，以及具有IOB为2.0的第二多元醇 组合物中的总含量为0质量％以下3质量％以下，其中，所述组合物中的表面活性剂的总含量为0质量％以下且1质量％以下，总质量 的组合物中的神经酰胺化合物的量为组合物中脂肪酸组分总质量的至少3.0倍。
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公开(公告)号：US20110177144A1
公开(公告)日：2011-07-21
申请号：US13121414
申请日：2009-09-30
IPC分类号： A61K8/02
摘要： The present invention provides an a aqueous cosmetic preparation which includes at least a ceramide analog-containing particle that contains at least a ceramide analog and has a volume average particle diameter of from 2 nm to 150 nm, the particle is dispersed in an aqueous phase as an oil-phase component, and a fatty acid having 10 to 30 carbon atoms or salt thereof. The aqueous cosmetic preparation satisfies at least either a condition where the pH is 5.5 or more or a condition where the electric conductivity is 5.0 mS/cm or less.
摘要翻译： 本发明提供一种水性化妆品制剂，其至少包含至少含有神经酰胺类似物的颗粒，其至少包含神经酰胺类似物，体积平均粒径为2nm至150nm，所述颗粒以水相分散为 油相成分，碳原子数为10〜30的脂肪酸或其盐。 水性化妆品至少满足pH5.5以上的条件或电导率为5.0mS / cm以下的条件。
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公开(公告)号：US20100330135A1
公开(公告)日：2010-12-30
申请号：US12667825
申请日：2008-07-01
申请人： Tomoko Tashiro , Toshiaki Kubo , Tatsuo Kawabuchi , Yukio Sudo
发明人： Tomoko Tashiro , Toshiaki Kubo , Tatsuo Kawabuchi , Yukio Sudo
摘要： A cosmetic composition contains: a carotenoid (A), a collagen (B) having an average molecular weight of 40,000 or more, and a collagen peptide (C) having a weight average molecular weight of from 200 to 5,000.
摘要翻译： 化妆品组合物含有：类胡萝卜素（A），平均分子量为40,000以上的胶原蛋白（B）和重均分子量为200〜5000的胶原肽（C）。
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8.发明申请DISPERSION COMPOSITION, COSMETIC PREPARATION FOR SKIN CARE, AND METHOD FOR PRODUCING DISPERSION COMPOSITION 审中-公开分散组合物，皮肤护理的化妆品制备和生产分散组合物的方法公开(公告)号：US20100021511A1
公开(公告)日：2010-01-28
申请号：US12522152
申请日：2007-12-27
申请人： Tatsuo Kawabuchi , Toshiaki Kubo , Manabu Ogawa , Keiichi Suzuki , Tomoko Tashiro , Yukio Sudo
发明人： Tatsuo Kawabuchi , Toshiaki Kubo , Manabu Ogawa , Keiichi Suzuki , Tomoko Tashiro , Yukio Sudo
摘要： The present invention provides: a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing the carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and an oily component that is 20% by mass or less relative to the mass of the whole dispersion composition, and the dispersion composition having emulsion particles having an average particle diameter of 200 nm or less; a dispersion composition including a carotenoid-containing oily component, the dispersion composition being obtained by mixing an aqueous dispersion containing emulsion particles containing a carotenoid-containing oily component and a phospholipid or a derivative thereof with an aqueous composition containing ascorbic acid or a derivative thereof and a pH adjusting agent, and the dispersion composition having a pH value in the range of 5 to 7.5; and a cosmetic preparation for skin care including one or other of the dispersion compositions.
摘要翻译： 本发明提供一种含有类胡萝卜素的油性成分的分散组合物，该分散组合物是将含有含有类胡萝卜素的油性成分的乳液粒子的含水分散体和磷脂或其衍生物与含有抗坏血酸的水性组合物 或其衍生物和油性成分相对于整个分散组合物的质量为20质量％以下，所述分散组合物具有平均粒径为200nm以下的乳液粒子; 包含含类胡萝卜素的油性成分的分散组合物，所述分散组合物通过将含有含类胡萝卜素的油性成分的乳液颗粒和磷脂或其衍生物的含水分散体与含有抗坏血酸或其衍生物的水性组合物混合而得到， pH调节剂，所述分散组合物的pH值在5〜7.5的范围内; 和用于皮肤护理的化妆品制剂，包括一种或其它分散组合物。
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公开(公告)号：US06855541B2
公开(公告)日：2005-02-15
申请号：US10676241
申请日：2003-10-01
IPC分类号： G01N33/53 , C12Q1/68 , G01N21/64 , G01N21/77 , G01N33/543 , G01N33/58 , G01N37/00 , C12M1/34
CPC分类号： G01N21/6452 , C12Q1/6816 , C12Q1/6837 , G01N21/6428 , G01N21/7703 , G01N33/54373 , G01N2021/6484 , G01N2021/772 , Y10S435/808 , Y10S435/81 , C12Q2565/601 , C12Q2565/518 , C12Q2563/107
摘要： This invention provides a kit used for fabricating an integrated biomolecule sensor. The kit includes an optical fiber bundle unit, which holds the proximal ends of the plurality of optical fibers together with the end-face arranged substantially in the same plane and oriented substantially in the same direction, a plate with wells for holding solutions containing probe polymers with different base sequences, and an auxiliary plate having holes, which corresponds to the wells of the plate respectively. According to this invention, researchers and other people can easily fabricate the integrated biomolecule under individual requirements without need of expensive equipment.
摘要翻译： 本发明提供了用于制造集成生物分子传感器的试剂盒。 该套件包括光纤束单元，该光纤束单元将多个光纤的近端保持在一起，并将端面基本上布置在相同的平面上并且基本上沿相同的方向定向，具有用于保持含有探针聚合物的溶液的孔的平板 具有不同的碱基序列和具有孔的辅助板，其分别对应于板的孔。 根据本发明，研究人员和其他人可以根据个人需求轻松制造整合的生物分子，而不需要昂贵的设备。
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公开(公告)号：US20120191746A1
公开(公告)日：2012-07-26
申请号：US12810684
申请日：2008-08-22
IPC分类号： G06F17/30
CPC分类号： G06F16/30
摘要： A dictionary system available for the use in document search or available for the use in normalization of a term constituting a document. A dictionary system capable of supporting a complex term composed of a plurality of simple terms. A dictionary system includes a storage for storing a simple term dictionary unit containing at least one simple term and a complex term dictionary unit which represents a complex term that contains one of the simple terms constituting the simple term dictionary unit. Each simple term constituting the complex term is referred to through a pointer (unit identifier) to the simple term dictionary unit.
摘要翻译： 一种字典系统，可用于文档搜索或可用于构成文档的术语的归一化。 一种能够支持由多个简单术语组成的复合术语的字典系统。 词典系统包括用于存储包含至少一个简单术语的简单术语字典单元的存储器和表示包含构成简单术语词典单元的简单术语之一的复数项的复数术语字典单元。 构成复合术语的每个简单术语通过简单术语词典单元的指针（单元标识符）来引用。
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