MATERIALS AND METHODS FOR DETECTING TOXINS, PATHOGENS AND OTHER BIOLOGICAL MATERIALS
    2.
    发明申请
    MATERIALS AND METHODS FOR DETECTING TOXINS, PATHOGENS AND OTHER BIOLOGICAL MATERIALS 有权
    用于检测毒素,病原体和其他生物材料的材料和方法

    公开(公告)号:US20140127675A1

    公开(公告)日:2014-05-08

    申请号:US14148945

    申请日:2014-01-07

    Abstract: Embodiments of the present invention provide binding molecule-functionalized high electron mobility transistors (HEMTs) that can be used to detect toxins, pathogens and other biological materials. In a specific embodiment, an antibody-functionalized HEMT can be used to detect botulinum toxin. The antibody can be anchored to a gold-layered gate area of theHEMT through immobilized thioglycolic acid. Embodiments of the subject detectors can be used in field-deployable electronic biological applications based on AlGaN/GaN HEMTs.

    Abstract translation: 本发明的实施方案提供可用于检测毒素,病原体和其他生物材料的结合分子官能化的高电子迁移率晶体管(HEMT)。 在具体实施方案中,抗体功能化的HEMT可用于检测肉毒杆菌毒素。 抗体可以通过固定化的巯基乙酸锚定在HEMT的金层门区。 本发明的检测器的实施例可以用于基于AlGaN / GaN HEMT的现场可部署电子生物学应用中。

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