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    IMPROVED FORMULATIONS FOR DRUG-COATED MEDICAL DEVICES
    4.
    发明申请
    IMPROVED FORMULATIONS FOR DRUG-COATED MEDICAL DEVICES 有权
    用于药物包衣医疗器械的改进配方

    公开(公告)号：US20130046237A1

    公开(公告)日：2013-02-21

    申请号：US13641941

    申请日：2010-11-03

    申请人： Ulrich Speck ,  Madeleine Caroline Berg

    发明人： Ulrich Speck ,  Madeleine Caroline Berg

    IPC分类号： A61M25/10

    CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416

    摘要： The present invention is related to a medical device carrying at least on a portion of its surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiarectic acid, resveratrol and propyl gallate, and wherein scoring or cutting balloons as medical devices are excluded.

    摘要翻译： 本发明涉及至少在其一部分表面上携带至少一种氧化不敏感药物或不含氧化物的无氧化物的药物制剂和至少一种亲脂性抗氧化剂，其比例为3-100重量％ 所述至少一种抗氧化剂相对于所述药物的100重量％，其中所述至少一种氧化不敏感药物选自紫杉烷类，沙利度胺，他汀类，皮质激素和皮质激素的亲脂性衍生物，并且所述至少一种亲脂性抗氧化剂是 选择去甲二氢越南酸，白藜芦醇和没食子酸丙酯，并且其中排除作为医疗装置的评分或切割气球。

    Formulations for drug-coated medical devices
    5.
    发明授权
    Formulations for drug-coated medical devices 有权

    公开(公告)号：US09974888B2

    公开(公告)日：2018-05-22

    申请号：US13641941

    申请日：2010-11-03

    申请人： Ulrich Speck ,  Madeleine Caroline Berg

    发明人： Ulrich Speck ,  Madeleine Caroline Berg

    IPC分类号： A61F2/00 ,  A61L29/16 ,  A61L31/16

    CPC分类号： A61L29/16 ,  A61L31/16 ,  A61L2300/416

    摘要： The present invention is related to a medical device carrying at least on a portion of its surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiarectic acid, resveratrol and propyl gallate, and wherein scoring or cutting balloons as medical devices are excluded.

    COATING FORMULATIONS FOR SCORING OR CUTTING BALLOON CATHETERS
    6.
    发明申请
    COATING FORMULATIONS FOR SCORING OR CUTTING BALLOON CATHETERS 有权
    用于分选或切割气泡导管的涂层配方

    公开(公告)号：US20130338572A1

    公开(公告)日：2013-12-19

    申请号：US13975209

    申请日：2013-08-23

    申请人： Ulrich Speck ,  Madeleine Caroline Berg

    发明人： Ulrich Speck ,  Madeleine Caroline Berg

    IPC分类号： A61M25/10

    CPC分类号： A61L29/08 ,  A61B17/320725 ,  A61B2017/320733 ,  A61L29/143 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2300/802 ,  A61M25/10 ,  A61M25/104 ,  A61M2025/105 ,  A61M2025/109

    摘要： The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiaretic acid, resveratrol and propyl gallate.

    摘要翻译： 本发明涉及评估或切割气球导管，其至少在其表面的一部分上携带至少一种氧化不敏感药物或不含氧化物的无氧化物的药物制剂和至少一种亲脂性抗氧化剂，其比例为3-100％ 的至少一种亲脂性抗氧化剂相对于100重量％的药物，其中所述至少一种氧化不敏感药物选自紫杉烷类，沙利度胺，他汀类，皮质激素和皮质激素的亲脂性衍生物，并且所述至少一种 亲脂性抗氧化剂选自去甲二氢愈创木酸，白藜芦醇和没食子酸丙酯。

    Use of intravenous contrast media for projection mammography
    10.
    发明申请
    Use of intravenous contrast media for projection mammography 审中-公开
    使用静脉造影剂进行投影乳房X线摄影

    公开(公告)号：US20050008574A1

    公开(公告)日：2005-01-13

    申请号：US10851213

    申请日：2004-05-24

    申请人： Ulrich Speck ,  Irtel Von Brenndorff

    发明人： Ulrich Speck ,  Irtel Von Brenndorff

    IPC分类号： A61B6/00 ,  A61K49/00 ,  A61K49/04 ,  A61K49/06 ,  A61P35/04 ,  G06T5/00 ,  G06T5/50

    CPC分类号： A61K49/0409 ,  A61K49/0457

    摘要： The invention relates to the use of intravenous contrast media for projection mammography as well as new devices for projection mammography. The invention therefore relates to the use of intravenous contrast media for the production of a diagnostic agent for projection mammography. Through the additional intravenous administration of contrast media, projection mammography achieves a sensitivity that is comparable to that of the most modern processes such as magnetic resonance tomography (MRT) while being considerably more versatile and avoiding the costs of MRT. The new process can be implemented simply and without special stress on the patients and provides a significant improvement in a) sensitivity to the detection of focal lesions in the breast, and b) additional information on the nature of lesions detected previously.

    摘要翻译： 本发明涉及用于投影乳房X线照相术的静脉造影剂的使用以及用于投影乳房X线照相术的新装置。 因此，本发明涉及静脉造影剂用于生产用于投影乳房X线照相术的诊断剂的用途。 通过额外静脉注射造影剂，投影乳房X线照相术的灵敏度可以达到最现代的方法，如磁共振断层扫描（MRT）的灵敏度，同时具有更大的灵活性，避免了MRT的成本。 新过程可以简单实现，对患者没有特别的压力，并且对a）对乳房局灶性病变检测的敏感度以及b）关于先前检测到的病变性质的额外信息提供了显着的改善。