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公开(公告)号:US20240058509A1
公开(公告)日:2024-02-22
申请号:US18499995
申请日:2023-11-01
CPC分类号: A61L29/085 , A61F2/2433 , A61L29/06 , A61L29/143 , A61M2025/1075
摘要: Balloon compositions that may be used for deployment of implants within a patient's body. The balloons in examples may be utilized for dilating implants and may be coupled to a delivery catheter for an implant. In examples, the balloons may be utilized to dilate other surfaces within the patient's body.
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公开(公告)号:US20230233742A1
公开(公告)日:2023-07-27
申请号:US18010653
申请日:2021-06-18
CPC分类号: A61L29/16 , A61L29/085 , A61L29/146 , A61L29/143 , A61L29/18 , A61L2420/02 , A61L2420/06 , A61L2400/12 , A61L2300/608
摘要: A drug-loaded medical device, a preparation method therefor, a drug balloon and a method of preparing a drug coating are disclosed. The medical device or the drug balloon is provided on a surface thereof with a drug coating including a stabilizer and a drug. The stabilizer includes an amphiphilic triblock polymer with hydrophilic segments at both terminals, and the drug coating forms a nano-drug particle suspension in a water-soluble environment. In this way, the prepared nano-drug coating has high drug loading and can deliver the drug in a desirable way. In particular, when it comes into contact with water, the drug can be restored to the original nano size, almost without any particle size increase. This not only avoids the risk of embolism caused by granules, but also enables higher device safety, increased drug uptake and improved therapeutic effects.
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公开(公告)号:US20190070341A1
公开(公告)日:2019-03-07
申请号:US16102497
申请日:2018-08-13
发明人: Ulrich Speck , Madeleine C. Berg
CPC分类号: A61L29/08 , A61B17/320725 , A61B2017/320733 , A61L29/143 , A61L29/16 , A61L31/16 , A61L2300/216 , A61L2300/416 , A61L2300/606 , A61L2300/802 , A61M25/10 , A61M25/104 , A61M2025/105 , A61M2025/109
摘要: The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiaretic acid, resveratrol and propyl gallate.
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公开(公告)号:US20190030301A1
公开(公告)日:2019-01-31
申请号:US16145421
申请日:2018-09-28
发明人: Aaron Khieu , John Jianhua Chen , Ying Xiong , Joe Khammoungkhoune , Daniel James Horn , John Blix
CPC分类号: A61M25/10 , A61L29/049 , A61L29/14 , A61L29/143 , A61M25/1002 , A61M25/1029 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , A61M2025/1088 , A61M2205/0216 , B32B5/02 , C08L23/06 , C08L75/04 , C08L77/00 , Y10T428/1334 , Y10T428/1352 , Y10T428/1362 , Y10T428/1366 , Y10T428/1372 , Y10T428/1386
摘要: Composite fiber reinforced balloons for medical devices are prepared by applying a web of fibers to the exterior of a preformed underlayer balloon, encasing the web with a matrix material to form an assembly, and inserting the assembly into a preformed outer layer balloon to form the composite balloon.
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公开(公告)号:US20180194042A1
公开(公告)日:2018-07-12
申请号:US15914176
申请日:2018-03-07
IPC分类号: B29C35/08 , C08L23/06 , A61L27/16 , A61L31/14 , A61L31/04 , A61L29/14 , A61L29/04 , A61L27/50 , C08K5/1545 , C08K5/00 , B29C43/00 , C08J3/28
CPC分类号: B29C35/0805 , A61L27/16 , A61L27/505 , A61L29/041 , A61L29/143 , A61L31/048 , A61L31/143 , B29C43/003 , C08J3/28 , C08K5/005 , C08K5/1545 , C08L23/06 , C08L2312/06 , Y10T29/49 , Y10T29/49995 , Y10T428/31855
摘要: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
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公开(公告)号:US09526873B2
公开(公告)日:2016-12-27
申请号:US14843564
申请日:2015-09-02
发明人: Aaron Khieu , John Jianhua Chen , Ying Xiong , Joe Khammoungkhoune , Daniel James Horn , John Blix
CPC分类号: A61M25/10 , A61L29/049 , A61L29/14 , A61L29/143 , A61M25/1002 , A61M25/1029 , A61M25/104 , A61M2025/1075 , A61M2025/1084 , A61M2025/1088 , A61M2205/0216 , B32B5/02 , C08L23/06 , C08L75/04 , C08L77/00 , Y10T428/1334 , Y10T428/1352 , Y10T428/1362 , Y10T428/1366 , Y10T428/1372 , Y10T428/1386
摘要: Composite fiber reinforced balloons for medical devices are prepared by applying a web of fibers to the exterior of a preformed underlayer balloon, encasing the web with a matrix material to form an assembly, and inserting the assembly into a preformed outer layer balloon to form the composite balloon.
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公开(公告)号:US09441081B2
公开(公告)日:2016-09-13
申请号:US12041249
申请日:2008-03-03
IPC分类号: A61L27/16 , A61L27/44 , A61L27/50 , A61L29/04 , A61L29/14 , A61L31/04 , A61L31/14 , C08K5/00 , C08K3/00 , C08L23/06 , C08J3/28 , C08J3/22
CPC分类号: A61L27/16 , A61L27/505 , A61L29/041 , A61L29/143 , A61L31/048 , A61L2430/02 , C08J3/226 , C08J3/247 , C08J3/28 , C08J2323/06 , C08J2423/00 , C08K5/1545 , C08K2201/012 , C08L23/06 , C08L2666/02 , C08K5/005
摘要: The present invention relates to methods for making cross-linked, oxidatively stable, and highly crystalline polymeric materials. The invention also provides methods of treating irradiation-cross-linked antioxidant-containing polymers and materials used therewith.
摘要翻译: 本发明涉及制备交联的,氧化稳定的和高度结晶的聚合物材料的方法。 本发明还提供了处理照射交联的含抗氧化剂的聚合物和与其一起使用的材料的方法。
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公开(公告)号:US09370878B2
公开(公告)日:2016-06-21
申请号:US13826930
申请日:2013-03-14
IPC分类号: B29C35/08 , A61L27/16 , A61L27/50 , B29C43/00 , C08K5/00 , C08K5/1545 , A61L29/04 , A61L29/14 , A61L31/04 , A61L31/14 , C08J3/28 , C08L23/06
CPC分类号: B29C35/0805 , A61L27/16 , A61L27/505 , A61L29/041 , A61L29/143 , A61L31/048 , A61L31/143 , B29C43/003 , C08J3/28 , C08K5/005 , C08K5/1545 , C08L23/06 , C08L2312/06 , Y10T29/49 , Y10T29/49995 , Y10T428/31855
摘要: The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein.
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公开(公告)号:US20160095960A1
公开(公告)日:2016-04-07
申请号:US14877284
申请日:2015-10-07
申请人: AngioScore, Inc.
IPC分类号: A61L29/08 , A61L29/14 , A61L29/16 , A61B17/3207 , A61M25/10
CPC分类号: A61L29/08 , A61B17/320725 , A61B2017/320733 , A61L29/143 , A61L29/16 , A61L31/16 , A61L2300/216 , A61L2300/416 , A61L2300/606 , A61L2300/802 , A61M25/10 , A61M25/104 , A61M2025/105 , A61M2025/109
摘要: The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.
摘要翻译: 本发明涉及评估或切割气球导管,其至少在其表面的一部分上携带至少一种药物或药物制剂和至少一种亲脂性抗氧化剂,其比例为至少一种亲脂性抗氧化剂的3-100重量% 相对于100重量%的药物,其中排除了至少一种药物和至少一种亲脂性抗氧化剂作为药物的组合,其中所述至少一种亲脂性抗氧化剂是丁基化羟基甲苯。
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公开(公告)号:US09301903B2
公开(公告)日:2016-04-05
申请号:US14230385
申请日:2014-03-31
申请人: Gerald Moss
发明人: Gerald Moss
CPC分类号: A61J15/0003 , A61J15/0049 , A61J15/0073 , A61L29/041 , A61L29/143 , A61M5/007 , A61M25/0026 , A61M2025/0035
摘要: A multi lumen gastrointestinal catheter is disclosed. The multi-lumen gastrointestinal catheter has a flexible partition separating a feeding and an aspiration channel. A third smaller inflation channel is positioned within the outside exterior wall at the site of the flexible partition to avoid kinking at the inflation channel site, without need to re-enforce the weakened wall.
摘要翻译: 公开了一种多腔胃肠导管。 多腔胃肠导管具有分隔进食和吸气通道的柔性隔板。 第三个较小的充气通道位于柔性隔板现场的外部外壁内,以避免在充气通道位置处扭结,而无需重新强化弱化壁。
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