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55 条记录 (耗时 0.032 秒)

    Sample carrier for cryoconservation of biological samples
    5.
    发明授权
    Sample carrier for cryoconservation of biological samples 有权
    用于生物样品低温保存的样品载体

    公开(公告)号：US07435582B2

    公开(公告)日：2008-10-14

    申请号：US10503371

    申请日：2003-01-29

    申请人： Ulrich Zimmermann ,  Heiko Zimmermann

    发明人： Ulrich Zimmermann ,  Heiko Zimmermann

    IPC分类号： C12M1/00

    CPC分类号： A01N1/02 ,  A01N1/0263 ,  A01N1/0268 ,  G01N1/42

    摘要： The invention relates to sample supports and methods for cryoconservation, especially the cryoconservation of biological materials, comprising at least one sample reservoir used to receive a biological sample. A support body is disposed in the sample reservoir, made of a material having a volume structure, consisting of a plurality of open, inner cavities which can be filled with the sample. The invention also relates to the use of motor vehicle catalyst-structure or biomorphic ceramics for producing support bodies used to receive samples for cryoconservation.

    摘要翻译： 本发明涉及用于低温保存的样品载体和方法，特别是生物材料的低温保存，其包含用于接收生物样品的至少一个样品储存器。 支撑体设置在样品容器中，由具有体积结构的材料制成，由多个可以填充样品的开放的内腔组成。 本发明还涉及机动车辆催化剂结构或生物陶瓷用于生产用于接收用于低温保存的样品的支撑体的用途。

    Measuring method for a semiconductor memory, and semiconductor memory
    6.
    发明申请
    Measuring method for a semiconductor memory, and semiconductor memory 失效
    半导体存储器和半导体存储器的测量方法

    公开(公告)号：US20070153598A1

    公开(公告)日：2007-07-05

    申请号：US11638766

    申请日：2006-12-14

    申请人： Ulrich Zimmermann

    发明人： Ulrich Zimmermann

    IPC分类号： G11C29/00

    CPC分类号： G11C29/50 ,  G11C11/401 ,  G11C29/50008 ,  G11C29/50016 ,  G11C2029/5002

    摘要： The invention relates to a semiconductor memory, and to a measuring method for a semiconductor memory. In one case, the method includes connecting a memory cell to a ring oscillator and measuring the frequency resulting for said ring oscillator.

    摘要翻译： 本发明涉及一种半导体存储器以及半导体存储器的测量方法。 在一种情况下，该方法包括将存储器单元连接到环形振荡器并测量所述环形振荡器产生的频率。

    Method for isolating and purifying enzymes from a crude enzyme solution
    8.
    发明授权
    Method for isolating and purifying enzymes from a crude enzyme solution 失效
    从粗酶溶液中分离和纯化酶的方法

    公开(公告)号：US4350767A

    公开(公告)日：1982-09-21

    申请号：US264022

    申请日：1981-05-15

    申请人： Ulrich Zimmermann ,  Mohammed Saleemuddin ,  Gunter Pilwat

    发明人： Ulrich Zimmermann ,  Mohammed Saleemuddin ,  Gunter Pilwat

    IPC分类号： B01D15/00 ,  B01J20/24 ,  C12N9/00 ,  C12N9/02 ,  C12N9/88 ,  C12N9/04

    CPC分类号： C12N9/0008 ,  C12N9/00 ,  C12N9/88 ,  C12Y102/01009 ,  Y10S435/815

    摘要： A method and adsorption medium for isolating and purifying enzymes from a crude enzyme solution of animal organs or tissues. An adsorption medium for bringing about the binding of a predetermined enzyme is introduced into the crude enzyme solution and is left therein until the binding takes place, whereupon the adsorption medium is removed from the crude enzyme solution and the enzyme is separated from the adsorption medium by extraction or elution with a suitable solution. The adsorption medium is in the form of membranes of human or animal erythrocytes which have been hemolyzed by osmosis. Those enzymes which have the same or nearly the same affinity as regards binding on the membranes as does the predetermined enzyme which is to be bound are separated from the membranes prior to introducing the membranes into the crude enzyme solution. The amount of the enzymes first removed that is bound being less than the amount of erythrocytes used to form the membranes.

    摘要翻译： 一种用于从动物器官或组织的粗酶溶液中分离和纯化酶的方法和吸附介质。 将用于实现预定酶的结合的吸附介质引入粗酶溶液中并留在其中直到发生结合，然后从粗酶溶液中除去吸附介质，并通过 用合适的溶液萃取或洗脱。 吸附介质是通过渗透溶血的人或动物红细胞的膜的形式。 在将膜引入粗酶溶液之前，将与膜结合相同或几乎相同的亲和力的酶与膜结合的预定酶分离。 首先除去的酶结合量少于用于形成膜的红细胞的量。

    Physiological preparation containing loaded cells of expanded volume in suspension, for preferential accumulation in spleen and liver
    9.
    发明授权
    Physiological preparation containing loaded cells of expanded volume in suspension, for preferential accumulation in spleen and liver 失效
    生理制剂含有悬浮液中膨胀体积的负载细胞，用于在脾脏和肝脏中优先积累

    公开(公告)号：US4289756A

    公开(公告)日：1981-09-15

    申请号：US860570

    申请日：1977-12-14

    申请人： Ulrich Zimmermann ,  Gunter Pilwat ,  Karin Bock ,  Hermann J. Buers

    发明人： Ulrich Zimmermann ,  Gunter Pilwat ,  Karin Bock ,  Hermann J. Buers

    IPC分类号： A61K9/50 ,  A61K35/12 ,  A61K35/18 ,  A61K37/48 ,  A61K35/14 ,  A61K43/00

    CPC分类号： A61K9/5068 ,  A61K35/12 ,  A61K35/18 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331

    摘要： Loaded cells suspended in a physiological solution are prepared in a process in which their volume is expanded by osmotic pressure. Cells so prepared suspended in a physiological solution, when injected into the bloodstream of a living body are preferentially accumulated in the spleen and liver of the body, which treats them as foreign bodies, even though the original cells may have been cells of an animal of the same species. Similarly by storing the loaded cells in a solution containing substances such as glutadialdehyde, formaldehyde that react with the protein phase of membranes or which, like difluoro dinitrobenzene, react with the lipid layer thereof, the loaded cells can also be caused to be broken down by the spleen and/or liver. Premature release of the contents of the loaded cells is prevented and timely release of such contents is assured by incorporating other materials into the loaded cells during the preparation process in accordance with the related application of the same inventors, Ser. No. 859,240 filed Dec. 9, 1977, now U.S. Pat. No. 4,224,313, issued Sept. 23, 1980.

    摘要翻译： 在其通过渗透压膨胀其体积的过程中制备悬浮在生理溶液中的负载细胞。 悬浮在生理溶液中的细胞在注射到生物体的血液中时优先蓄积在身体的脾脏和肝脏中，即将其视为异物，尽管原始细胞可能是动物的细胞 相同的物种 类似地，通过将​​负载的细胞储存在含有诸如谷丙二醛，甲醛与膜的蛋白质相反应的物质的溶液中，或者像二氟二硝基苯一样与其脂质层反应的负载细胞也可以被分解， 脾脏和/或肝脏。 防止负载的电池的内容物的过早释放，根据相同发明人的相关申请，在制备过程中，通过将其它材料并入加载的电池中来确保这些内容物的及时释放。 1977年12月9日提交的第859,240号，现为美国专利 1980年9月23日发布的第4,224,313号。

    Physiological preparation containing loaded cells in suspension and a magnetic agent for local concentration thereof in a living body
    10.
    发明授权
    Physiological preparation containing loaded cells in suspension and a magnetic agent for local concentration thereof in a living body 失效
    含有悬浮液中的负载细胞的生理制剂和用于在活体中局部浓缩的磁性剂

    公开(公告)号：US4269826A

    公开(公告)日：1981-05-26

    申请号：US859563

    申请日：1977-12-12

    申请人： Ulrich Zimmermann ,  Gunter Pilwat

    发明人： Ulrich Zimmermann ,  Gunter Pilwat

    IPC分类号： A61K9/50 ,  A61K35/12 ,  A61K35/18 ,  A61K45/08 ,  C12N13/00 ,  A61K35/14 ,  A61K37/48 ,  A61K43/00

    CPC分类号： A61K35/18 ,  A61K35/12 ,  A61K9/5068 ,  A61K9/5094

    摘要： Magnetic substances in particles of a diameter in the range between 1 and 20 nm are suspended in the physiological solution by which cells are loaded with materials when their cell membranes have increased permeability, the magnetic materials being provided in such dosing, that when the cells are loaded, separated from the loading solution and prepared for use in a fresh physiological solution, thereafter injected to a living body, they can be collected and held fast at a predetermined location, for example, at the location of a tumor, by the effect of an external magnetic field. Ferritin, magnetite, cobalt ferrite, nickel ferrite and other ferrimagnetic, ferromagnetic or even paramagnetic compounds can be incorporated into loaded cells for this purpose.

    摘要翻译： 直径在1至20nm范围内的颗粒中的磁性物质悬浮在生理溶液中，细胞在其细胞膜具有增加的渗透性时被装载材料，磁性材料以这种剂量提供，当细胞为 加载，与装载溶液分离并准备用于新鲜的生理溶液中，然后注射到生物体中，可以在预定的位置（例如在肿瘤的位置）快速收集和保持，通过 外部磁场。 铁素体，磁铁矿，钴铁氧体，镍铁氧体和其他铁磁性，铁磁性或甚至顺磁性化合物可以结合到装载的电池中用于此目的。