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公开(公告)号:USD1023338S1
公开(公告)日:2024-04-16
申请号:US29770970
申请日:2021-02-18
Applicant: Ultima Genomics, Inc.
Designer: Nathan Beckett , Jacob Wolf , Keith Allen , Ryan Rosenfeld , Anh Nguyen , Hoang Nguyen
Abstract: FIG. 1 is a front, right perspective view of a sequencer machine, showing our new design;
FIG. 2 is a top, rear, left perspective view thereof;
FIG. 3 is a front elevation view thereof;
FIG. 4 is a right elevation view thereof;
FIG. 5 is a rear elevation view;
FIG. 6 is a left elevation view thereof;
FIG. 7 is a top plain view;
FIG. 8 is an enlarged view of detail “8” identified in FIG. 3; and,
FIG. 9 is an enlarged view of detail “9” identified in FIG. 5.
In the drawings, the equal-length broken lines depict portions of the sequencer machine and form no part of the claimed design. The dash-dot-dash broken lines define the limits of the enlarged portions shown. All broken lines form no part of the claim.-
公开(公告)号:US11904322B2
公开(公告)日:2024-02-20
申请号:US17673444
申请日:2022-02-16
Applicant: Ultima Genomics, Inc.
Inventor: Jose Martin Sosa , Joseph Anthony , Nathan Beckett , Gilad Almogy , Chandan Shee , Phillip You Fai Lee , Yuto Watanabe
CPC classification number: B01L7/52 , B01L3/508 , B01L2200/0647 , B01L2300/1805 , B01L2400/0415 , C12Q1/686
Abstract: The present disclosure provides methods and processes for increasing the efficiency and accuracy of nucleic acid sequencing using techniques such as polymerase chain reaction (PCR). Methods and systems provided herein may facilitate performing reactions such as emulsion PCR (ePCR) on samples comprising nucleic acids and beads. The methods provided herein may provide a higher throughput compared to existing technologies.
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公开(公告)号:US11155868B2
公开(公告)日:2021-10-26
申请号:US17155226
申请日:2021-01-22
Applicant: Ultima Genomics, Inc.
Inventor: Gilad Almogy , Nathan Beckett , Jacob A. Wolf , Nathan Caswell , Joseph Anthony , Jose Martin Sosa , Phillip Lee , Stephanie Kubecka
IPC: C12Q1/6874 , C12Q1/6825 , C12Q1/6809 , B01J19/00 , B01L3/00
Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.
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公开(公告)号:US11499962B2
公开(公告)日:2022-11-15
申请号:US16862196
申请日:2020-04-29
Applicant: Ultima Genomics, Inc.
Inventor: Kristopher Barbee , Nathan Beckett , Denis Pristinski , Derek Schulte , Avishai Bartov , Jamie Sullivan , Dumitru Brinza , Abizar Lakdawalla , Steven Menchen , Gilad Almogy , Mark Pratt
Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.
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公开(公告)号:USD956263S1
公开(公告)日:2022-06-28
申请号:US29740346
申请日:2020-07-02
Applicant: Ultima Genomics, Inc.
Designer: Nathan Beckett , Joseph Anthony , Phillip You Fai Lee , Jose Martin Sosa
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公开(公告)号:US11268143B2
公开(公告)日:2022-03-08
申请号:US17308241
申请日:2021-05-05
Applicant: Ultima Genomics, Inc.
Inventor: Nathan Beckett , Gilad Almogy , Nathan Caswell , Jacob A. Wolf , Kristopher Barbee , Denis Pristinski , Mark Pratt , Gene Polovy , Osip Schwartz , Stephanie Kubecka , Steven Menchen , Joseph Anthony , Jose Martin Sosa , Phillip You Fai Lee
IPC: C12Q1/68 , G01N35/10 , C12Q1/6874
Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.
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公开(公告)号:US11118223B2
公开(公告)日:2021-09-14
申请号:US16953071
申请日:2020-11-19
Applicant: Ultima Genomics, Inc.
Inventor: Gilad Almogy , Nathan Beckett , Stephanie Kubecka
IPC: G01N35/00 , C12Q1/6874 , G01N35/10 , C12Q1/68
Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.
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公开(公告)号:US12188924B2
公开(公告)日:2025-01-07
申请号:US18224378
申请日:2023-07-20
Applicant: Ultima Genomics, Inc.
Inventor: Kristopher Barbee , Nathan Beckett , Denis Pristinski , Derek Schulte , Avishai Bartov , Jamie Sullivan , Dumitru Brinza , Abizar Lakdawalla , Steven Menchen , Gilad Almogy , Mark Pratt
Abstract: Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate configured to rotate. The open substrate can comprise an array of immobilized analytes. A solution comprising a plurality of probes may be directed, via centrifugal force, across the array during rotation of the substrate, to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via continuous rotational area scanning of the substrate.
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公开(公告)号:US11732298B2
公开(公告)日:2023-08-22
申请号:US16416856
申请日:2019-05-20
Applicant: Ultima Genomics, Inc.
Inventor: Gilad Almogy , Kristopher Barbee , Nathan Beckett
IPC: C12Q1/6874 , C12Q1/6809 , C12Q1/6825 , B01J19/00 , B01L3/00 , G01N33/543 , C12Q1/6834
CPC classification number: C12Q1/6874 , B01J19/0046 , B01L3/50273 , B01L3/502715 , C12Q1/6809 , C12Q1/6825 , B01J2219/00536 , B01J2219/00596 , B01J2219/00605 , B01J2219/00689 , B01J2219/00702 , B01J2219/00722 , B01L3/5023 , B01L2200/026 , B01L2200/0647 , B01L2300/0654 , B01L2400/0409 , C12Q1/6834 , G01N33/54366 , C12Q1/6874 , C12Q2565/629 , C12Q1/6834 , C12Q2565/629
Abstract: Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.
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公开(公告)号:US11512350B2
公开(公告)日:2022-11-29
申请号:US17089781
申请日:2020-11-05
Applicant: Ultima Genomics, Inc.
Inventor: Gilad Almogy , Kristopher Barbee , Nathan Beckett
IPC: C12Q1/6874 , C12Q1/6809 , C12Q1/6825 , B01J19/00 , B01L3/00 , G01N33/543 , C12Q1/6834
Abstract: Provided are methods for biological sample processing and analysis. A method can comprise providing a substrate configured to rotate. The substrate can comprise an array having immobilized thereto a biological analyte. A solution comprising a plurality of probes may be directed, via centrifugal force, across the substrate during rotation of the substrate, to couple at least one of the plurality of probes with the biological analyte. A detector can be configured to detect a signal from the at least one probe coupled to the biological analyte, thereby analyzing the biological analyte.
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