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    Medicine for treating apoptosis dysfunction containing oligosaccharides
    3.
    发明授权
    Medicine for treating apoptosis dysfunction containing oligosaccharides 失效
    用于治疗含有寡糖的凋亡功能障碍的药物

    公开(公告)号：US06750208B1

    公开(公告)日：2004-06-15

    申请号：US09601665

    申请日：2000-12-28

    申请人： Jean-Claude Yvin ,  Florence Cruz ,  Valérie Descamps ,  Christophe Richard ,  Vesna Thibal ,  Patrick Arrigo ,  Bernard Cloarec

    发明人： Jean-Claude Yvin ,  Florence Cruz ,  Valérie Descamps ,  Christophe Richard ,  Vesna Thibal ,  Patrick Arrigo ,  Bernard Cloarec

    IPC分类号： A61K31715

    CPC分类号： A61K31/702

    摘要： The invention concerns a medicine comprising, as active principle, an efficient quantity of at least an oligosaccharide substance capable of modulating apoptosis dysfunction which is capable of modifying apoptosis dysfunctions said substance being selected from the group consisting of oligosaccharides which are derived, by enzymatic or chemical process, from the polymers of the group comprising (1→3)-&bgr;-glucans which optionally comprise (1→6)-&bgr;-branching, and oligosaccharides which are derived, by enzymatic or chemical process, from sulfated galactans, it also concerns a method for treating apoptosis dysfunction.

    摘要翻译： 本发明涉及一种药物，其包含有效量的至少一种能够调节凋亡功能障碍的寡糖物质的能力，所述寡糖物质能够修饰凋亡功能障碍，所述物质选自由通过酶促或化学衍生的寡糖 （1-> 6） - 支化的（1-> 3）β-葡聚糖的聚合物和通过酶促或化学方法从硫酸化半乳糖衍生的寡糖， 还涉及治疗凋亡功能障碍的方法。

    Genes coding for &bgr;-agarases and their use for producing agar biodegradation enzymes
    6.
    发明授权
    Genes coding for &bgr;-agarases and their use for producing agar biodegradation enzymes 有权
    编码β-琼脂糖的基因及其用于生产琼脂生物降解酶的用途

    公开(公告)号：US06511838B1

    公开(公告)日：2003-01-28

    申请号：US09719402

    申请日：2000-12-12

    申请人： Didier Flament ,  Tristan Barbeyron ,  Jean-Claude Yvin ,  Philippe Potin ,  Bernard Kloareg

    发明人： Didier Flament ,  Tristan Barbeyron ,  Jean-Claude Yvin ,  Philippe Potin ,  Bernard Kloareg

    IPC分类号： C12N900

    CPC分类号： C12Y302/01081 ,  C12N9/2468 ,  C12R1/01

    摘要： The invention relates to the novel Cytophaga drobachiensis strain deposited in the DSMZ Collection (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures)) on May 8, 1998 under the number DSM 12170, the agaA gene coding for a &bgr;-agarase and having SEQ ID No. 1, the agaB gene coding for a &bgr;-agarase and having SEQ ID No. 3, said genes coding for a &bgr;-agarase of Cytophaga drobachiensis DSM 12170, and the specific nucleic acid sequence of the agaA gene coding for a specific peptide fragment AgaA′ which has conserved &bgr;-agarase activity, and having SEQ ID No. 5, as well as the protein AgaA of C. drobachiensis DSM 12170 having SEQ ID No. 2, the protein AgaB of C. drobachiensis DSM 12170 having SEQ ID No. 4 and said peptide fragment AgaA′ of C. drobachiensis DSM 12170 having SEQ ID No. 6.

    摘要翻译： 本发明涉及存在于DSMZ Collection（Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH（German Collection of Microorganisms and Cell Cultures））中的新颖的细胞托氏菌（Cytophaga drobachiensis），编号为DSM 12170，编码为β的agaA基因 - 具有SEQ ID No.1，编码β-琼脂糖酶并具有SEQ ID No.3的agaB基因的所述编码所述的编码Cytophaga drobachiensis DSM 12170的β-琼脂糖酶的基因，以及agaA的特异性核酸序列 编码具有保守的β-琼脂糖酶活性并具有SEQ ID No.5的特异性肽片段AgaA'的基因，以及具有SEQ ID No.2的C. drobachiensis DSM 12170的蛋白质AgaA，C的蛋白质AgaB。 具有SEQ ID No.4的drobachiensis DSM 12170和具有SEQ ID No.6的C. drobachiensis DSM 12170的所述肽片段AgaA'。

    Agent for stimulation of the natural defences of plants and methods for using it
    9.
    发明授权
    Agent for stimulation of the natural defences of plants and methods for using it 有权
    用于刺激植物自然防御的代理和使用它的方法

    公开(公告)号：US06979665B2

    公开(公告)日：2005-12-27

    申请号：US10371460

    申请日：2003-02-20

    申请人： Jean-Claude Yvin ,  Rozenn Menard ,  Serge Kauffmann ,  Bernard Fritig

    发明人： Jean-Claude Yvin ,  Rozenn Menard ,  Serge Kauffmann ,  Bernard Fritig

    IPC分类号： A01N43/16

    CPC分类号： A01N43/16

    摘要： The invention relates to a method for the stimulation of the reactions of natural defence of agronomically useful and of decorative plants, characterized by the fact that there is applied on the plants to be treated an aqueous composition comprising an efficient concentration in sulfate of β 1-3 glucan and more particularly a concentration of at least 1 mg/l, preferably of at least 5 mg/l, and still more preferably of at least 10 mg/l in laminarin sulfate, whose degree of sulfatation is higher than or equal to 1.9, preferably from 2 to 2.5, the said composition being applied to the culture or crop to be treated in an amount sufficient to provide per hectare an efficient amount of sulfate of β 1-3 glucan, and in the case of laminarin sulfate in an amount sufficient to provide from 0.4 to 4 g of laminarin sulfate per hectare.

    摘要翻译： 本发明涉及一种用于刺激农业有用和装饰植物的天然防御反应的方法，其特征在于将待处理的植物施用于水性组合物，该水性组合物包含硫酸盐中的有效浓度为β1- 3葡聚糖，更特别是在硫酸化程度高于或等于1.9的硫酸铵中，至少1mg / l，优选至少5mg / l，甚至更优选至少10mg / l的浓度 ，优选为2至2.5，所述组合物以足以提供每公顷有效量的β1-3葡聚糖的硫酸盐的量施用到待处理的培养物或作物上，并且在硫酸昆布酸盐的量的情况下 足以提供每公顷0.4至4g硫酸昆布硫酸钙。