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公开(公告)号：US20160326535A1
公开(公告)日：2016-11-10
申请号：US15110158
申请日：2015-01-08
CPC分类号： C12N15/81 , C07K14/395 , C12N9/1025 , C12P7/06 , C12P7/16 , C12P13/04 , C12Q1/6897 , G01N33/5038 , Y02E50/10 , Y02E50/17
摘要： Metabolic flux biosensors are provided herein, as are related compositions and methods useful for, inter alia, identifying factors which increase the production of metabolites and/or end products of metabolic pathways, and for the production of inter alia, metabolites and/or end products of metabolic pathways.
摘要翻译： 代谢通量生物传感器在本文中提供，以及用于特别是鉴定增加代谢途径的代谢物和/或最终产物的生成以及用于生产代谢物和/或最终产物的因素的相关组合物和方法 的代谢途径。
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2.发明公开公开(公告)号：US20240287549A1
公开(公告)日：2024-08-29
申请号：US18572167
申请日：2022-06-23
发明人： Felix Lam , Gregory Stephanopoulos , Gerald Fink
CPC分类号： C12P7/10 , C12N9/0006 , C12Y101/01028 , C12Y101/01283
摘要： The present disclosure provides, in various aspects, engineered alcohol tolerant yeast and methods of producing high concentrations of biofuels and bioplastics from toxic feedstocks.
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公开(公告)号：US20150072391A1
公开(公告)日：2015-03-12
申请号：US14479118
申请日：2014-09-05
发明人： Felix Lam , Gerald Fink , Gregory Stephanopoulos
CPC分类号： C12P7/10 , C07K14/39 , C12N15/81 , C12P7/04 , C12P7/16 , C12Y101/01001 , C12Y101/01021 , C12Y102/01005 , Y02E50/10 , Y02E50/16 , Y02E50/17
摘要： The present disclosure provides, in various aspects, engineered alcohol tolerant yeast and methods of producing high concentrations of ethanol.
摘要翻译： 本公开在各个方面提供了工程醇耐受酵母和生产高浓度乙醇的方法。
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公开(公告)号：US11041161B2
公开(公告)日：2021-06-22
申请号：US15110158
申请日：2015-01-08
IPC分类号： C12N15/81 , C12P7/16 , C12Q1/6897 , C12P13/04 , C12P7/06 , C12N9/10 , C07K14/395 , G01N33/50
摘要： Metabolic flux biosensors are provided herein, as are related compositions and methods useful for, inter alia, identifying factors which increase the production of metabolites and/or end products of metabolic pathways, and for the production of inter alia, metabolites and/or end products of metabolic pathways.
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公开(公告)号：US20210340577A1
公开(公告)日：2021-11-04
申请号：US17314561
申请日：2021-05-07
IPC分类号： C12P5/00 , C12P17/02 , C12P23/00 , C12P15/00 , C12P7/42 , C12P19/56 , C12N15/70 , C12P9/00 , C12Q1/689
摘要： The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
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公开(公告)号：US10519470B2
公开(公告)日：2019-12-31
申请号：US15924700
申请日：2018-03-19
IPC分类号： C12P5/00 , C12Q1/689 , C12P9/00 , C12N15/70 , C12P19/56 , C12P7/42 , C12P23/00 , C12P17/02 , C12P15/00
摘要： The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
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公开(公告)号：US10294481B2
公开(公告)日：2019-05-21
申请号：US15281994
申请日：2016-09-30
IPC分类号： C12N15/70 , C12N9/00 , C12P7/42 , C12N9/04 , C12N9/02 , C12N9/12 , C12N9/88 , C12N9/90 , C12N15/52
摘要： Some aspects provide engineered microbes for glycolate production. Methods for microbe engineering and culturing are also provided herein. Such engineered microbes exhibit greatly enhanced capabilities for glycolate production.
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8.发明授权Engineered microbes and methods for microbial oil overproduction from cellulosic materials 有权用于微生物油从纤维素材料过度生产的工程微生物和方法公开(公告)号：US09096876B2
公开(公告)日：2015-08-04
申请号：US13923607
申请日：2013-06-21
CPC分类号： C12N9/92 , C12N9/0006 , C12P7/6463 , C12P7/649 , C12P2203/00 , C12Y101/01009 , C12Y101/0101 , C12Y101/01307 , C12Y503/01005 , Y02E50/13 , Y02E50/17
摘要： The invention relates to engineering microbial cells for utilization of cellulosic materials as a carbon source, including xylose.
摘要翻译： 本发明涉及用于利用纤维素材料作为碳源（包括木糖）的工程微生物细胞。
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公开(公告)号：US10006065B2
公开(公告)日：2018-06-26
申请号：US14311527
申请日：2014-06-23
CPC分类号： C12P7/6409 , C12N9/001 , C12N9/0071 , C12N15/815 , C12P7/6463
摘要： Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some aspects of this invention relate to the discovery of a key regulator of lipid metabolism in microbes. Some aspects of this invention relate to engineered microbes for biofuel or biofuel precursor production.
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公开(公告)号：US20160355849A1
公开(公告)日：2016-12-08
申请号：US15142877
申请日：2016-04-29
IPC分类号： C12P7/56
摘要： Aspects of the invention relate to methods for producing lactic acid from organic waste, comprising contacting organic waste with a microbial community to form a fermentation mixture, and fermenting the fermentation mixture under controlled pH and temperature conditions for a time sufficient to produce lactic acid.
摘要翻译： 本发明的方面涉及从有机废物生产乳酸的方法，包括使有机废物与微生物群落接触以形成发酵混合物，并在受控的pH和温度条件下将发酵混合物发酵足以产生乳酸的时间。
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