摘要:
Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
摘要:
Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
摘要:
Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
摘要:
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, wherein D1, D2 and D3 are each N, CH, or substituted CH, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.
摘要:
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.
摘要:
A 2×2 opto-mechanical switch is disclosed. A first embodiment of the present invention utilizes a transmitting compact parallel prism and four or two pieces of the 45-degree prism to increase the beam separation. The compact parallel prism keeps a much smaller load to the relay arm. This makes the current invention less sensitive to the ambient shock and vibration. A second embodiment of the present invention utilizes a similar transmitting compact parallel prism and two wedge prisms which has similar advantages. The compact prism applies a small loading force to the relay arm. Both of these embodiments also feature superior thermal and mechanical stability. An opto-mechanical switch in accordance with the present invention utilizes a transmitting design and thus is more stable to ambient thermal or mechanical change. The embodiments of the present invention also feature much better repeatability than the conventional 2×2 optical switches.
摘要:
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.
摘要:
A method, equipment and system for implementing coordinated multi-point transmission are provided for resolving the problem that there exists phase noise in the signals received by a User Equipment (UE) end in coordinated multi-point transmission. The method for implementing coordinated multi-point transmission includes: obtaining phase differences between the current service cell and other coordinated cells by calculating channel cross-covariance matrixes between the current service cell and other coordinated cells in a coordinated multi-point transmission system (101); feeding back the phase differences corresponding to the base stations of said other coordinated cells respectively to the base stations of said other coordinated cells, in order to implement phase compensation (102); receiving the signals transmitted after the phase compensation by base stations of all the coordinated cells (103). The method, terminal and system provided by the embodiments of the present invention are applicable to the coordinated communication in various wireless networks.
摘要:
Substituted spirocyclic amines of structural formula I are selective antagonists of the somatostatin sub-type receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.
摘要:
A method, equipment and system for implementing coordinated multi-point transmission are provided for resolving the problem that there exists phase noise in the signals received by a User Equipment (UE) end in coordinated multi-point transmission. The method for implementing coordinated multi-point transmission includes: obtaining phase differences between the current service cell and other coordinated cells by calculating channel cross-covariance matrixes between the current service cell and other coordinated cells in a coordinated multi-point transmission system (101); feeding back the phase differences corresponding to the base stations of said other coordinated cells respectively to the base stations of said other coordinated cells, in order to implement phase compensation (102); receiving the signals transmitted after the phase compensation by base stations of all the coordinated cells (103). The method, terminal and system provided by the embodiments of the present invention are applicable to the coordinated communication in various wireless networks.