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    Models for vaccine assessment
    8.
    发明申请
    Models for vaccine assessment 有权
    疫苗评估模型

    公开(公告)号：US20080008653A1

    公开(公告)日：2008-01-10

    申请号：US11819335

    申请日：2007-06-27

    申请人： John Tew ,  Mohey Eldin El Shikh ,  Inderpal Singh ,  Eric Mishkin ,  Donald Drake ,  Haifeng Song ,  William Warren

    发明人： John Tew ,  Mohey Eldin El Shikh ,  Inderpal Singh ,  Eric Mishkin ,  Donald Drake ,  Haifeng Song ,  William Warren

    IPC分类号： A61K39/00 ,  A01K67/00 ,  A61K49/00 ,  A61P43/00 ,  C12N5/06

    CPC分类号： A01K67/0271 ,  A01K2267/0337 ,  A61K49/0008

    摘要： The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.

    摘要翻译： 本发明涉及用于构建和使用人体免疫方面的体内和体外模型的方法，特别是建立用于例如疫苗，佐剂，免疫治疗候选物，化妆品的测试的人类免疫系统模型 ，药物，生物制剂等化学品。 本发明包括可用于评估物质与免疫系统的相互作用的人体免疫方面的体内和体外模型，因此可用于加速和提高例如疫苗的准确性和可预测性， 药物，生物，免疫治疗，化妆品和化学发展。 本发明也可用于产生人单克隆抗体和多克隆抗体。

    Models for vaccine assessment
    9.
    发明授权
    Models for vaccine assessment 有权
    疫苗评估模型

    公开(公告)号：US07709257B2

    公开(公告)日：2010-05-04

    申请号：US11819335

    申请日：2007-06-27

    申请人： John G. Tew ,  Mohey Eldin M. El Shikh ,  Inderpal Singh ,  Eric Mishkin ,  Donald Drake, III ,  Haifeng Song ,  William L Warren

    发明人： John G. Tew ,  Mohey Eldin M. El Shikh ,  Inderpal Singh ,  Eric Mishkin ,  Donald Drake, III ,  Haifeng Song ,  William L Warren

    IPC分类号： C12N5/00 ,  C12N5/02 ,  C12N5/16

    CPC分类号： A01K67/0271 ,  A01K2267/0337 ,  A61K49/0008

    摘要： The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.

    摘要翻译： 本发明涉及用于构建和使用人体免疫方面的体内和体外模型的方法，特别是建立用于例如疫苗，佐剂，免疫治疗候选物，化妆品的测试的人类免疫系统模型 ，药物，生物制剂等化学品。 本发明包括可用于评估物质与免疫系统的相互作用的人体免疫方面的体内和体外模型，因此可用于加速和提高例如疫苗的准确性和可预测性， 药物，生物，免疫治疗，化妆品和化学发展。 本发明也可用于产生人单克隆抗体和多克隆抗体。