公开(公告)号：US07314971B2

公开(公告)日：2008-01-01

申请号：US10345072

申请日：2003-01-15

Applicant: Gregory G. Brown ,  Charles Dendy ,  Benoit S. Landry ,  Wing Cheung ,  Hua Jin ,  Fang-Ming Lai ,  Natasa Formanova ,  Martin LaForest

Inventor： Gregory G. Brown ,  Charles Dendy ,  Benoit S. Landry ,  Wing Cheung ,  Hua Jin ,  Fang-Ming Lai ,  Natasa Formanova ,  Martin LaForest

IPC: C12N15/82 ,  C12N15/29 ,  A01H1/02 ,  A01H5/00

CPC classification number: C12N15/8287 ,  C07K14/415 ,  C12N15/1034 ,  C12N15/821 ,  C12N15/8289

Abstract: The present invention includes nuclear fertility restorer genes, proteins encoded by those genes and transgenic plants and plant cells containing those genes. More particularly, the nuclear fertility restorer genes can be used to restore fertility in cytoplasmic male-sterile plants such as Brassica napus. Preferably, the nuclear fertility restorer genes are used with the Ogura (ogu) CMS system in Brassica napus.

Abstract translation: 本发明包括核能恢复基因，由这些基因编码的蛋白质和转基因植物以及含有这些基因的植物细胞。 更具体地说，核生育恢复基因可用于恢复细胞质雄性不育植物如甘蓝型油菜中的生育力。 优选地，

公开(公告)号：US20050267026A1

公开(公告)日：2005-12-01

申请号：US11088284

申请日：2005-03-24

Applicant: Wing Cheung

Inventor： Wing Cheung

IPC: A61K38/18

CPC classification number: A61K38/1816

Abstract: The present invention provides a combination dosing regimen for erythropoietin (EPO). More particularly, the present dosing regimen includes administration of at least a first dosing segment comprising a first exposure to EPO capable of stimulating the production of reticulocytes followed by a second exposure to EPO capable of sustaining the maturation of the reticulocytes into neocytes, and ultimately, red blood cells. Advantageously, the dosing segment may be cycled or repeated, any number of times and according to any desired time scheme, in order to provide or maintain any desired total red blood cell count and/or hemoglobin concentration. Methods of treatment employing the combination dosing regimen, as well as kits are also provided.

Abstract translation: 本发明提供促红细胞生成素（EPO）的组合给药方案。 更具体地，本发明的给药方案包括施用至少第一给药段，其包含能够刺激网织红细胞生成的EPO的第一次暴露，然后第二次暴露于能够维持网织红细胞成熟为新细胞的EPO， 红细胞。 有利地，给药段可以循环或重复任意次数，并且根据任何期望的时间方案，以便提供或维持任何期望的总红细胞计数和/或血红蛋白浓度。 还提供了使用联合给药方案的治疗方法以及试剂盒。

公开(公告)号：US6067563A

公开(公告)日：2000-05-23

申请号：US306588

申请日：1999-05-06

Applicant: Robert E. Thomas ,  Douglas M. Washabaugh ,  Peter J. Roman ,  Wing Cheung

Inventor： Robert E. Thomas ,  Douglas M. Washabaugh ,  Peter J. Roman ,  Wing Cheung

IPC: G06F11/30 ,  H04L12/56 ,  H04L29/06 ,  H04Q11/04 ,  G06F13/00

CPC classification number: H04L47/522 ,  G06F11/3006 ,  G06F11/3027 ,  G06F11/3055 ,  G06F11/3096 ,  H04L29/06 ,  H04L47/521 ,  H04L49/90 ,  H04L49/901 ,  H04L49/9036 ,  H04Q11/0478 ,  H04L2012/5616 ,  H04L2012/5635 ,  H04L2012/5658 ,  H04L2012/5679 ,  H04L2012/5681

Abstract: A mechanism for avoiding an initiation of control read transactions on a system bus coupling a host system having a host memory and an interface connected to a peripheral unit as data is moved between the host system and the peripheral unit is presented. Control information associated with data memory portions in host memory is written to the interface for data memory portions storing outgoing data and data memory portions to receive incoming data. The interface includes a controller to move data between the host memory and the interface by first obtaining the control information for the associated data portions. The interface writes status reports in association with the movement of data between the interface and the host memory via the system bus. The mechanism thus enables data transfers to occur via the system without the initiation of control reads in absence of an exception condition.

Abstract translation: 提出了一种用于避免在系统总线上启动控制读取事务的机制，该系统总线耦合具有主机存储器的主机系统和连接到外围单元的接口，因为数据在主机系统和外围设备之间移动。 将与主机存储器中的数据存储器部分相关联的控制信息写入存储输出数据和数据存储器部分的数据存储器部分的接口以接收输入数据。 该接口包括控制器，用于通过首先获得相关联的数据部分的控制信息来在主机存储器和接口之间移动数据。 该接口通过系统总线写入与接口和主机存储器之间的数据移动相关联的状态报告。 因此，该机制使得能够在没有异常条件的情况下通过系统进行数据传输而不启动控制读取。

公开(公告)号：US5970229A

公开(公告)日：1999-10-19

申请号：US707896

申请日：1996-09-12

Applicant: Robert E. Thomas ,  Peter J. Roman ,  Wing Cheung

Inventor： Robert E. Thomas ,  Peter J. Roman ,  Wing Cheung

IPC: G06F13/38 ,  G06F13/00

CPC classification number: G06F13/387

Abstract: An apparatus and method for transferring data from a source memory (e.g. a host memory) to a peripheral interface via a bus utilizes a transmit buffer memory coupled to the peripheral interface, and a current time counter advancing at the rate at which data is to be transferred from the transmit buffer memory to the peripheral interface. A schedule table data structure stores entries in some or all of its locations, where each location corresponds to a point in time at which data is to be transferred from the transmit buffer memory to the peripheral interface. A schedule table pointer is used for pointing to successive locations in the schedule table. The schedule table pointer advances at a rate faster than the current time counter advances so that the schedule table pointer represents a point in time which is ahead of the point in time currently output by the current time counter. A data transfer is initiated from the source memory to the transmit buffer memory via the bus when a valid entry is stored at the location in the schedule table pointed to by the schedule table pointer. The data is then transferred out of the transmit buffer memory to the peripheral interface when the current time counter reaches the value representing at least the same point in time that was represented by the schedule table pointer when the data transfer was initiated. Data transfers from the transmit buffer memory are thereby synchronized in time with their corresponding entries in the schedule table.

Abstract translation: 用于经由总线将数据从源存储器（例如，主机存储器）传送到外围接口的装置和方法利用耦合到外围接口的发送缓冲存储器和以数据的速率前进的当前时间计数器 从发送缓冲存储器传送到外设接口。 调度表数据结构存储其部分或全部位置中的条目，其中每个位置对应于将数据从发送缓冲存储器传送到外围接口的时间点。 调度表指针用于指向调度表中的连续位置。 调度表指针以比当前时间计数器更快的速率前进，使得调度表指针表示在当前时间计数器当前输出的时间点之前的时间点。 当有效条目存储在调度表指针指向的调度表中的位置时，通过总线从源存储器发送到发送缓冲存储器的数据传输。 然后，当当前时间计数器达到表示数据传输启动时由调度表指针表示的至少相同的时间点的值时，将数据传送到发送缓冲存储器中的外设接口。 因此，从发送缓冲存储器的数据传输在时间上与其在调度表中的相应条目同步。

公开(公告)号：US5941952A

公开(公告)日：1999-08-24

申请号：US712687

申请日：1996-09-12

Applicant: Robert E. Thomas ,  Peter J. Roman ,  Wing Cheung

Inventor： Robert E. Thomas ,  Peter J. Roman ,  Wing Cheung

IPC: H04L12/56 ,  H04Q11/04 ,  G06F13/38 ,  G06F15/17

CPC classification number: H04Q11/0478 ,  H04L2012/5616 ,  H04L2012/5635 ,  H04L2012/5658 ,  H04L2012/5664 ,  H04L2012/5667 ,  H04L2012/5679 ,  H04L2012/5681

Abstract: An apparatus and method for transferring data from a source memory to a transmit buffer memory and then from the transmit buffer memory at a particular rate. A current time counter advances at the rate at which data is to be transmitted from the transmit buffer memory to the interface. A schedule memory stores entries, each valid entry being associated with data that is to be transmitted from the transmit buffer memory to the interface. A timestamp is associated with each valid entry in the schedule memory. Circuitry is then operative on each valid entry read from the schedule table to generate a request for a data transfer between the source memory and the transmit buffer memory; perform a data transfer from the source memory to the transmit buffer memory in response to the request; and transfer the data from the transmit buffer memory when the current time circuitry output reaches a value representing at least the same point in time that is represented by the timestamp associated with the entry for which the request was generated.

Abstract translation: 一种用于将数据从源存储器传送到发送缓冲存储器然后以特定速率从发送缓冲存储器传送的装置和方法。 当前时间计数器以数据从发送缓冲存储器发送到接口的速率前进。 调度存储器存储条目，每个有效条目与要从发送缓冲存储器发送到接口的数据相关联。 时间戳与调度存储器中的每个有效条目相关联。 然后对从调度表读取的每个有效条目进行电路以产生对源存储器和发送缓冲存储器之间的数据传输的请求; 响应于该请求，执行从源存储器到发送缓冲存储器的数据传输; 并且当当前时间电路输出达到表示与由生成请求的条目相关联的时间戳表示的至少相同的时间点的值时，传送来自发送缓冲存储器的数据。

公开(公告)号：US10033650B2

公开(公告)日：2018-07-24

申请号：US13048817

申请日：2011-03-15

Applicant: Shunjia Yu ,  Anoop Ghanwani ,  Phanidhar Koganti ,  John Michael Terry ,  Wing Cheung ,  Joseph Juh-En Cheng ,  Surya P. Varanasi

Inventor： Shunjia Yu ,  Anoop Ghanwani ,  Phanidhar Koganti ,  John Michael Terry ,  Wing Cheung ,  Joseph Juh-En Cheng ,  Surya P. Varanasi

IPC: H04L12/723 ,  H04L12/66 ,  H04J1/16 ,  H04L12/857 ,  H04L12/46 ,  H04L12/701 ,  H04L12/721

Abstract: Systems and techniques for processing and/or forwarding packets are described. An ingress switch can use a QoS mapping mechanism to map a first set of Quality of Service (QoS) bits in a packet received from a customer to a second set of QoS bits for use in a Transparent Interconnection of Lots of Links (TRILL) packet which encapsulates the packet. The first set of QoS bits can be different from the second set of QoS bits. The TRILL packet can be processed and/or forwarded in the network based on the second set of QoS bits. At the egress switch, the TRILL packet can be decapsulated and the original packet with the original QoS bits (or QoS bits that are different from the original QoS bits) can be forwarded to the customer's network. In this manner, some embodiments of the present invention can preserve the QoS bits across a TRILL network.

公开(公告)号：US20130031077A1

公开(公告)日：2013-01-31

申请号：US13284829

申请日：2011-10-28

Applicant: Jian Liu ,  Philip Lynn Leichty ,  How Tung Lim ,  John Michael Terry ,  Mahesh Srinivasa Maddury ,  Wing Cheung ,  Kung Ling Ko

Inventor： Jian Liu ,  Philip Lynn Leichty ,  How Tung Lim ,  John Michael Terry ,  Mahesh Srinivasa Maddury ,  Wing Cheung ,  Kung Ling Ko

IPC: G06F17/30

CPC classification number: G06F7/02 ,  H04L45/7457 ,  H04L45/748

Abstract: A LPM search engine includes a plurality of exact match (EXM) engines and a moderately sized TCAM. Each EXM engine uses a prefix bitmap scheme that allows the EXM engine to cover multiple consecutive prefix lengths. Thus, instead of covering one prefix length L per EXM engine, the prefix bitmap scheme enables each EXM engine to cover entries having prefix lengths of L, L+1, L+2 and L+3, for example. As a result, fewer EXM engines are potentially underutilized, which effectively reduces quantization loss. Each EXM engine provides a search result with a determined fixed latency when using the prefix bitmap scheme. The results of multiple EXM engines and the moderately sized TCAM are combined to provide a single search result, representative of the longest prefix match. In one embodiment, the LPM search engine supports 32-bit IPv4 (or 128-bit IPv6) search keys, each having associated 15-bit level 3 VPN identification values.

Abstract translation: LPM搜索引擎包括多个精确匹配（EXM）引擎和中等大小的TCAM。 每个EXM引擎使用前缀位图方案，允许EXM引擎涵盖多个连续的前缀长度。 因此，代替覆盖每个EXM引擎的一个前缀长度L，例如，前缀位图方案使得每个EXM引擎能够覆盖具有前缀长度为L，L + 1，L + 2和L + 3的条目。 因此，较少的EXM引擎潜在地未充分利用，这有效地减少了量化损失。 当使用前缀位图方案时，每个EXM引擎提供具有确定的固定延迟的搜索结果。 多个EXM引擎和中等大小的TCAM的结果被组合以提供单个搜索结果，代表最长的前缀匹配。 在一个实施例中，LPM搜索引擎支持32位IPv4（或128位IPv6）搜索密钥，每个具有关联的15位3级VPN标识值。

公开(公告)号：US20060019326A1

公开(公告)日：2006-01-26

申请号：US11183115

申请日：2005-07-15

Applicant: Joseph Vacanti ,  Robert Rubin ,  Wing Cheung

Inventor： Joseph Vacanti ,  Robert Rubin ,  Wing Cheung

IPC: C12Q1/34 ,  C12Q1/42

CPC classification number: C12Q1/48 ,  B33Y80/00 ,  C12Q1/00 ,  C12Q1/18 ,  C12Q1/26 ,  C12Q1/34 ,  C12Q1/42 ,  C12Q1/44 ,  G01N33/5038 ,  G01N33/5088

Abstract: The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

Abstract translation: 本发明一般涉及组织工程，药物发现和药物开发领域的组合。 它更具体地提供了用于测试实验药物的功效和安全性，定义实验药物的代谢途径和表征现有药物的性质（例如副作用，新用途）的新方法和材料。 优选地，在三维组织工程系统中进行评价，其中可以确定药物毒性，代谢，相互作用和/或功效。

公开(公告)号：US06747002B2

公开(公告)日：2004-06-08

申请号：US09569612

申请日：2000-05-10

Applicant: Wing Cheung ,  David Gibson ,  Christine Cote ,  Els Vercammen

Inventor： Wing Cheung ,  David Gibson ,  Christine Cote ,  Els Vercammen

IPC: A61K3819

CPC classification number: G06F19/3437 ,  A61K38/00 ,  A61K38/1816 ,  G06F19/00 ,  G06F19/704 ,  G16H50/50 ,  A61K38/14 ,  A61K33/24 ,  A61K31/70 ,  A61K31/505 ,  A61K31/475 ,  A61K31/28 ,  A61K2300/00

Abstract: The present invention relates to systems and methods for obtaining optimized EPO dosage regimens for a desired pharmacodynamic/pharmacokinetic response. The system includes choosing one or more EPO dosage regimens, then using a PK/PD model to determine the pharmacodynamic/pharmacokinetic profile of one or more EPO dosage regimens, and finally selecting one of the EPO dosage regimens for administration to achieve the desired pharmacodynamic/pharmacodynamic response based on the EPO profile.

公开(公告)号：US06604709B1

公开(公告)日：2003-08-12

申请号：US10078859

申请日：2002-02-20

Applicant: Mark E. Wentland ,  Wing Cheung ,  Kevin Shimasaki

Inventor： Mark E. Wentland ,  Wing Cheung ,  Kevin Shimasaki

IPC: B64D1102

CPC classification number: B64D11/02 ,  B64D11/00

Abstract: An expandable, modular, multi-mode lavatory for aircraft featuring its multi-mode use as a lavatory, shower and accommodations for handicapped persons. The invention comprises a primary structure with a volume that expands into adjacently located unused space, such as an aircraft's main entry cross-aisleway. Deployable walls and doors are used to create a partitioned environment. A false bottom shower pan cover provides structural support for wheelchairs while also being removable to reveal a modular shower pan for bathing.

Abstract translation: 用于飞机的可扩展的，模块化的多模式洗手间，其多模式用作洗手间，淋浴和残疾人的住宿。 本发明包括具有扩展成相邻位置的未使用空间的体积的主要结构，例如飞行器的主入口横走道。 可部署的墙壁和门用于创建分区环境。 假底淋浴盘盖为轮椅提供结构支撑，同时也可移动，以露出用于沐浴的模块化淋浴盘。