公开(公告)号：US20130011385A1

公开(公告)日：2013-01-10

申请号：US13520076

申请日：2010-12-23

申请人： Xinsheng Li ,  Wankei Wan ,  Chandrakant J. Panchal

发明人： Xinsheng Li ,  Wankei Wan ,  Chandrakant J. Panchal

IPC分类号： C08L33/14 ,  A61K38/02 ,  A61K31/715 ,  A61K39/395 ,  B32B27/30 ,  A61K47/32 ,  A61K48/00 ,  B82Y30/00

CPC分类号： C08J3/24 ,  C08F2/00 ,  C08F2/44 ,  C08J3/075 ,  C08J2333/04 ,  C08L1/02 ,  C08L33/066 ,  Y10S977/773 ,  Y10S977/906 ,  Y10T428/31935

摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.

摘要翻译： 提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC） 。 公开了聚合物纳米复合材料水凝胶的合成路线。 优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。 然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。 公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。 所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

公开(公告)号：US08940337B2

公开(公告)日：2015-01-27

申请号：US13520076

申请日：2010-12-23

申请人： Xinsheng Li ,  Wankei Wan ,  Chandrakant J. Panchal

发明人： Xinsheng Li ,  Wankei Wan ,  Chandrakant J. Panchal

IPC分类号： A61K9/50 ,  C08J3/24 ,  C08F2/00 ,  C08F2/44 ,  C08J3/075 ,  C08L1/02 ,  C08L33/06

CPC分类号： C08J3/24 ,  C08F2/00 ,  C08F2/44 ,  C08J3/075 ,  C08J2333/04 ,  C08L1/02 ,  C08L33/066 ,  Y10S977/773 ,  Y10S977/906 ,  Y10T428/31935

摘要： A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength. The disclosed polymer nanocomposite hydrogel and compositions pertain to hydrogel applications, particularly contact lenses and optic components for biosensor.

摘要翻译： 提供了一种透明聚合物纳米复合材料水凝胶，其中聚合纳米复合材料水凝胶由水不溶性聚合物制成，即聚（甲基丙烯酸2-羟乙酯）（PHEMA）或/和交联的PHEMA和水不溶性纳米纤维，即细菌纤维素（BC） 。 公开了聚合物纳米复合材料水凝胶的合成路线。 优选的聚合物纳米组合物通过在细菌纤维素存在下在超声波辅助下的HEMA单体的自由基聚合来生产，以增强细菌纤维素，引发剂和单体的混合。 然后通过将干燥聚合物纳米复合物浸入水中形成聚合物纳米复合材料水凝胶。 公开了一种高透光率聚合物纳米复合水凝胶，其优选BC载量小于0.1％，水含量为约40重量％，良好的机械完整性和强度。 所公开的聚合物纳米复合材料水凝胶和组合物涉及水凝胶应用，特别是用于生物传感器的隐形眼镜和光学部件。

公开(公告)号：US08776791B2

公开(公告)日：2014-07-15

申请号：US11951479

申请日：2007-12-06

申请人： Lintao Huang ,  Xinsheng Li ,  Ruiling Pan ,  Xiaoyong Zhou

发明人： Lintao Huang ,  Xinsheng Li ,  Ruiling Pan ,  Xiaoyong Zhou

IPC分类号： A61M16/00 ,  A62B9/02

CPC分类号： A61M16/205 ,  A61M16/0051 ,  A61M16/0075 ,  A61M16/0081 ,  A61M16/01 ,  A61M16/024 ,  A61M16/204 ,  A61M2016/0033 ,  A61M2016/0036 ,  A61M2205/50 ,  A61M2205/702

摘要： A respiration apparatus and a method for calibrating respiration parameters thereof are provided. A flow measuring reference component arranged behind the inspiratory valve in the ventilator is used as a flow measuring reference sensor for calibrating the flow sensor so that the flow rates of the gas through the flow measuring reference component and the flow sensor to be calibrated are identical or in a corresponding relation. Electrical parameters output from the flow sensor and the flow measuring reference component are respectively acquired and processed to obtain a relation curve of the gas flow rate and the electrical parameter of the flow sensor on the basis of the read gas flow rate and the electrical parameters of the flow sensor. The present invention enables automatic calibration for a flow sensor without using any measuring instrument.

摘要翻译： 提供了一种用于校准其呼吸参数的呼吸装置和方法。 使用布置在呼吸机吸气阀之后的流量测量参考部件作为流量测量参考传感器，用于校准流量传感器，使得通过流量测量参考部件和要校准的流量传感器的气体的流量相同或 在相应的关系。 分别获取并处理从流量传感器和流量测量基准部件输出的电气参数，根据读取的气体流量和电气参数获得流量传感器的气体流量和电气参数的关系曲线 流量传感器。 本发明能够在不使用任何测量仪器的情况下自动校准流量传感器。

公开(公告)号：US20060194928A1

公开(公告)日：2006-08-31

申请号：US11339852

申请日：2006-01-26

申请人： Paul Charpentier ,  Xinsheng Li

发明人： Paul Charpentier ,  Xinsheng Li

IPC分类号： C08F10/00

CPC分类号： B82Y30/00 ,  C08F10/00 ,  C08F210/02 ,  C08G83/001 ,  C08J5/005 ,  Y02P20/544 ,  Y10T428/31667 ,  Y10T428/31692 ,  Y10T428/31855 ,  Y10T428/31938 ,  C08F4/32 ,  C08F2/14 ,  C08F2/44 ,  C08F218/08

摘要： A one step synthetic route of polymeric compositions of a polyolefin and inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthetic route combines parallel reactions of free radical polymerization to form polymer, and hydrolysis of either Si, or Zr, or Ti or both of them precursors. The network consisting of Si, Zr, Ti, is chemically bonded to or within the polymer matrix. The inorganic or organic molecules can then be polymerized under conditions effective to cause the polymerized inorganic or organic molecules into macromolecular networks. The compositions of the polymeric composites can be easily controlled by adjusting the reactant ratio and reaction rate or conditions such as temperature and pressure, wherein the inorganic compositions disperse in nanoscale within polymeric composites when their concentrations fall below moderate levels. A novel synthesis route for making polymer composites and/or polymer nanocomposites of a polyolefin and an inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthesis route comprises hydrolysis of either Si, or Zr, or Ti alkoxides or mixtures of these precursors within a polymer matrix in supercritical fluids.

摘要翻译： 公开了由选自Si，Zr，Ti的组分组成的聚烯烃和无机网络的聚合物组合物的一步合成途径。 合成路线结合自由基聚合的平行反应形成聚合物，以及Si或Zr或Ti或它们两者前体的水解。 由Si，Zr，Ti组成的网络化学键合到聚合物基体内或内。 然后可以在有效地使聚合的无机或有机分子进入大分子网络的条件下使无机或有机分子聚合。 聚合物复合材料的组成可以通过调节反应物比例和反应速率或诸如温度和压力的条件来容易地控制，其中当聚合物复合物的浓度低于中等水平时，无机组合物在纳米级分散。 公开了一种用于制备聚烯烃和/或由选自Si，Zr，Ti的组分组成的无机网络的聚合物复合材料和/或聚合物纳米复合材料的新型合成途径。 合成路线包括在超临界流体中在聚合物基质内水解Si或Zr或Ti醇盐或这些前体的混合物。

公开(公告)号：US07763357B2

公开(公告)日：2010-07-27

申请号：US11339852

申请日：2006-01-26

申请人： Paul A. Charpentier ,  Xinsheng Li

发明人： Paul A. Charpentier ,  Xinsheng Li

IPC分类号： C08L11/00

CPC分类号： B82Y30/00 ,  C08F10/00 ,  C08F210/02 ,  C08G83/001 ,  C08J5/005 ,  Y02P20/544 ,  Y10T428/31667 ,  Y10T428/31692 ,  Y10T428/31855 ,  Y10T428/31938 ,  C08F4/32 ,  C08F2/14 ,  C08F2/44 ,  C08F218/08

摘要： A one step synthetic route of polymeric compositions of a polyolefin and inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthetic route combines parallel reactions of free radical polymerization to form polymer, and hydrolysis of either Si, or Zr, or Ti or both of them precursors. The network consisting of Si, Zr, Ti, is chemically bonded to or within the polymer matrix. The inorganic or organic molecules can then be polymerized under conditions effective to cause the polymerized inorganic or organic molecules into macromolecular networks. The compositions of the polymeric composites can be easily controlled by adjusting the reactant ratio and reaction rate or conditions such as temperature and pressure, wherein the inorganic compositions disperse in nanoscale within polymeric composites when their concentrations fall below moderate levels. A novel synthesis route for making polymer composites and/or polymer nanocomposites of a polyolefin and an inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthesis route comprises hydrolysis of either Si, or Zr, or Ti alkoxides or mixtures of these precursors within a polymer matrix in supercritical fluids.

摘要翻译： 公开了由选自Si，Zr，Ti的组分组成的聚烯烃和无机网络的聚合物组合物的一步合成途径。 合成路线结合自由基聚合的平行反应形成聚合物，以及Si或Zr或Ti或它们两者前体的水解。 由Si，Zr，Ti组成的网络化学键合到聚合物基体内或内。 然后可以在有效地使聚合的无机或有机分子进入大分子网络的条件下使无机或有机分子聚合。 聚合物复合材料的组成可以通过调节反应物比例和反应速率或诸如温度和压力的条件来容易地控制，其中当聚合物复合物的浓度低于中等水平时，无机组合物在纳米级分散。 公开了一种用于制备聚烯烃和/或由选自Si，Zr，Ti的组分组成的无机网络的聚合物复合材料和/或聚合物纳米复合材料的新型合成途径。 合成路线包括在超临界流体中在聚合物基质内水解Si或Zr或Ti醇盐或这些前体的混合物。

公开(公告)号：US07582873B2

公开(公告)日：2009-09-01

申请号：US11323703

申请日：2005-12-30

申请人： Xinsheng Li ,  Huiling Zhou ,  Wei Zhang ,  Jilun Ye

发明人： Xinsheng Li ,  Huiling Zhou ,  Wei Zhang ,  Jilun Ye

IPC分类号： G01N21/35

CPC分类号： G01N21/3504 ,  G01N21/274 ,  G01N21/314 ,  G01N2021/3133 ,  G01N2021/3174 ,  G01N2021/3188

摘要： Disclosed is a method and apparatus for detecting the type of anesthetic gas. The method comprises the steps of: generating a light with a plurality of wavelengths, the light being able to be separated to a plurality of light beams whose central frequencies correspond to the plurality of wavelengths; passing said light through a gas chamber, wherein, the gas chamber being filled with said anesthetic gas, said anesthetic gas having absorption characteristic with respect to said plurality of light beams; detecting the light intensity of the attenuated light beams transmitted from the gas chamber respectively, to obtain the relative absorption characteristic of said attenuated light beams, which attenuated light beams having been absorbed by said anesthetic gas; and determining the type of said anesthetic gas based on the relative absorption characteristic between said attenuated light beams.

摘要翻译： 公开了一种用于检测麻醉气体类型的方法和装置。 该方法包括以下步骤：产生具有多个波长的光，该光能够被分离成多个光束，其中心频率对应于多个波长; 使所述光通过气室，其中，所述气室充满所述麻醉气体，所述麻醉气体相对于所述多个光束具有吸收特性; 分别检测从气室传递的衰减光束的光强度，以获得衰减了被所述麻醉气体吸收的光束的所述衰减光束的相对吸收特性; 以及基于所述衰减的光束之间的相对吸收特性确定所述麻醉气体的类型。

公开(公告)号：US20070163579A1

公开(公告)日：2007-07-19

申请号：US11636082

申请日：2006-12-08

申请人： Xinsheng Li ,  Xiaoyong Zhou

发明人： Xinsheng Li ,  Xiaoyong Zhou

IPC分类号： A61M15/00 ,  A61M16/00

CPC分类号： A61M16/0081 ,  A61M16/0051 ,  A61M16/024 ,  A61M2016/0036

摘要： A method and an apparatus for monitoring and controlling flows in medical equipment including an anesthetic machine and a ventilator for influencing a patient's respiratory system are disclosed. The apparatus comprises a microprocessor and an airway system comprising drive gas conduits provided with an inhalation valve (2) and an exhalation valve (5) for gas discharging as well as a ventilator end flow sensor (3) for measuring the introduced or discharged drive gas flow through the valves. The airway system also comprises patient end breathing tubing in which a patient end flow sensor (11) for measuring the patient's inspired and expired gas flow is provided. By comparing the measured values of the two flow sensors against the characteristic curve of the inhalation valve (2), the microprocessor can judge the operation states and accuracy of the respective flow sensors and the inhalation valve (2).

摘要翻译： 公开了一种用于监测和控制医疗设备中的流量的方法和装置，包括用于影响患者呼吸系统的麻醉机和呼吸机。 该装置包括微处理器和气道系统，其包括设置有用于排气的吸入阀（2）和呼气阀（5）的驱动气体导管以及用于测量引入或排出的驱动气体的通气机端流量传感器（3） 流过阀门。 气道系统还包括患者末端呼吸管，其中提供用于测量患者的启发和呼气的气流的患者端流量传感器（11）。 通过将两个流量传感器的测量值与吸入阀（2）的特性曲线进行比较，微处理器可以判断各个流量传感器和吸入阀（2）的运行状态和精度。