摘要:
Certain cells, including types of cancer cells such as melanoma cells, are capable of expressing junctophilin-like (JPL) RNA. Targeting using JPL polypeptides, nucleic acids encoding for JPL polypeptides and anti-JPL antibodies provides a method of killing or inhibiting that growth of melanoma cancer cells that express the JPL protein. Targeting materials and methods for the diagnosis and therapy of melanomas that express JPL are described.
摘要:
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to the novel polynucleotides and polypeptides. Other aspects of the invention include vectors containing processes for producing novel polypeptides, and antibodies specific for such polypeptides.
摘要:
Methods and apparatus for data synchronization in communication systems using repetitive preamble patterns. In one embodiment, a method includes receiving a signal, where the received signal includes a data unit. The data unit includes a preamble symbol, and the preamble symbol has a start time and includes Q portions, each having the same pattern. The method further includes determining multiple possible values of a frame timing (FT). The method further includes determining multiple correlation functions including at least one correlation function corresponding to each of the multiple possible values of the FT, such that a given correlation function corresponding to a given possible value of the FT represents a correlation between data in two non-adjacent portions of the Q portions associated with the given FT. The method further includes selecting one of the multiple possible values of the FT based at least in part on the multiple determined correlation functions.
摘要:
A system including a magnitude measuring module, an energy normalization module, and a metric generation module. The magnitude measuring module is configured to measure magnitudes of real portions of differentially demodulated signals, wherein the differentially demodulated signals are generated by differential demodulation of signals received from a base station. The energy normalization module is configured to generate a sum of energies of a plurality of subcarriers included in the signals received from the base station. The metric generation module is configured to generate a plurality of metrics for a plurality of symbols included in the signals received from the base station. The metric generation module is further configured to detect, based on the plurality of metrics, a preamble symbol included in the signals received from the base station.
摘要:
A process has been found which increases the efficiency and effectiveness of introducing antimicrobial compounds into complex biofilm matrices through the use of liposome carriers, thereby removing the biofouling in industrial water bearing systems, including piping, heat exchanges, condensers, filtration systems and fluid storage tanks.According to one embodiment of the invention, antimicrobial compound containing liposomes are added to water systems prone to biofouling and biofilm formation. The liposomes, being similar in composition to microbial membranes or cells, are readily incorporated into the existing biofilm. Once the antimicrobial compound containing liposomes become entrained with the biofilm matrix, the decomposition or programmed disintegration of the liposome proceeds. Thereafter the biocidal aqueous core is released to react directly with the biofilm encased microorganisms. Upon the death of the organisms, the polysaccharide/protein matrix decomposes and thereby results in reduced fouling of the water bearing system, resulting in increased heat transfer, increased flux, less deposit of colloidal and particulate solids and dissolved organics on the surface of the microfiltration membrane, thereby reducing the frequency and duration of the membrane cleaning and ultimate replacement.