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公开(公告)号：US06335177B1
公开(公告)日：2002-01-01
申请号：US09347001
申请日：1999-07-02
申请人： Yasuhiro Mihara , Sonoko Takeuchi , Yasuko Jojima , Naoto Tonouchi , Ryosuke Fudou , Kenzo Yokozeki
发明人： Yasuhiro Mihara , Sonoko Takeuchi , Yasuko Jojima , Naoto Tonouchi , Ryosuke Fudou , Kenzo Yokozeki
IPC分类号： C12P100
摘要： According to the present invention, there are provided microorganisms having an ability to producing xylitol or D-xylulose by fermentation, and a method for producing xylitol or D-xylulose using the microorganisms. Osmophilic microorganisms were collected from soil, and the obtained microorganisms were searched for a bacterium having an ability to produce xylitol or D-xylulose from glucose. Xylitol or D-xylulose is produced by culturing an isolated bacterium in a suitable medium to accumulate xylitol or D-xylulose in the medium, and collecting xylitol or D-xylulose from the medium.
摘要翻译： 根据本发明，提供了通过发酵生产木糖醇或D-木酮糖的能力的微生物，以及使用微生物生产木糖醇或D-木酮糖的方法。 从土壤中收集渗透性微生物，并从所得微生物中搜索具有从葡萄糖产生木糖醇或D-木酮糖的能力的细菌。 通过在合适的培养基中培养分离的细菌以在培养基中积累木糖醇或D-木酮糖并从培养基中收集木糖醇或D-木酮糖来生产木糖醇或D-木酮糖。
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2.发明授权公开(公告)号：US08389241B2
公开(公告)日：2013-03-05
申请号：US13611827
申请日：2012-09-12
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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3.发明授权公开(公告)号：US08329428B2
公开(公告)日：2012-12-11
申请号：US13211834
申请日：2011-08-17
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US20100267082A1
公开(公告)日：2010-10-21
申请号：US12729656
申请日：2010-03-23
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US20080166761A1
公开(公告)日：2008-07-10
申请号：US11841151
申请日：2007-08-20
申请人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US20120003693A1
公开(公告)日：2012-01-05
申请号：US13211834
申请日：2011-08-17
申请人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US07531340B2
公开(公告)日：2009-05-12
申请号：US11841211
申请日：2007-08-20
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
IPC分类号： C12N9/10 , C12N15/00 , C12P13/04 , C12P21/04 , C12Q1/00 , C12Q1/48 , C07H21/04 , C12Q1/68 , C12N1/20
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US07736876B2
公开(公告)日：2010-06-15
申请号：US12141428
申请日：2008-06-18
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US08039232B2
公开(公告)日：2011-10-18
申请号：US12729656
申请日：2010-03-23
申请人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi Hara , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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公开(公告)号：US20080274530A1
公开(公告)日：2008-11-06
申请号：US12141428
申请日：2008-06-18
申请人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
发明人： Seiichi HARA , Kenzo Yokozeki , Isao Abe , Naoto Tonouchi , Yasuko Jojima
IPC分类号： C12N9/00
摘要： DNA and recombinant DNA that encode a peptide-forming enzyme, a method for producing a peptide-forming enzyme, and a method for producing a dipeptide are disclosed. A method for producing a dipeptide includes producing a dipeptide from a carboxy component and an amine component by using a culture of a microbe belonging to the genus Sphingobacterium and having the ability to form the dipeptide from the carboxy component and the amine component, a microbial cell separated from the culture, treated microbial cell product of the microbe or a peptide-forming enzyme derived from the microbe.
摘要翻译： 公开了编码肽形成酶的DNA和重组DNA，产生肽形成酶的方法及其制备方法。 制备二肽的方法包括通过使用属于鞘氨醇杆菌属的微生物的培养物从羧基组分和胺组分制备二肽并具有从羧基组分和胺组分形成二肽的能力，微生物细胞 与培养物分离，处理微生物的微生物细胞产物或源自微生物的肽形成酶。
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