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    Laser pulmonary vein isolation
    1.
    发明授权
    Laser pulmonary vein isolation 有权
    激光肺静脉隔离

    公开(公告)号：US06997924B2

    公开(公告)日：2006-02-14

    申请号：US10245613

    申请日：2002-09-17

    申请人： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

    发明人： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

    IPC分类号： A61B18/18

    CPC分类号： A61B18/24 ,  A61B2017/22051 ,  A61B2018/2272

    摘要： A catheter introduction apparatus provides an optical assembly for emission of laser light energy. In one application, the catheter and the optical assembly are introduced percutaneously, and transseptally advanced to the ostium of a pulmonary vein. An anchoring balloon is expanded to position a mirror near the ostium of the pulmonary vein, such that light energy is reflected and directed circumferentially around the ostium of the pulmonary vein when a laser light source is energized. A circumferential ablation lesion is thereby produced, which effectively blocks electrical propagation between the pulmonary vein and the left atrium.

    摘要翻译： 导管引入装置提供用于发射激光能量的光学组件。 在一个应用中，导管和光学组件经皮引入，经皮递送到肺静脉的口。 锚固气囊被扩张以在靠近肺静脉的口处定位镜子，使得当激光源被激发时，光能被反射并周向地环绕肺静脉的口引导。 从而产生圆周消融损伤，其有效阻止肺静脉与左心房之间的电传播。

    Intracardiac pressure monitoring method
    3.
    发明授权
    Intracardiac pressure monitoring method 有权

    公开(公告)号：US06652464B2

    公开(公告)日：2003-11-25

    申请号：US09739062

    申请日：2000-12-18

    申请人： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

    发明人： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

    IPC分类号： A61B502

    CPC分类号： A61B5/6882 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/076 ,  A61B2560/0219 ,  A61B2562/0233 ,  A61B2562/046 ,  Y10S128/903

    摘要： A method for telemetrically measuring a parameter in a patient's heart comprises the steps of imaging the heart and identifying an implantation site in the heart. An opening is created in the tissue at the implantation site. A sensor comprising a housing, a membrane at one end of the housing wherein the membrane is deformable in response to the parameter, and a microchip positioned within the housing and operatively communicating with the membrane for transmitting a signal indicative of the parameter is provided. The sensor is placed in the opening and the parameter is telemetrically measured from outside of the patient's body based on the transmitted signal by the sensor. The sensor is also telemetrically powered from outside of the patient's body. A signal charging and reading device is placed outside of the patient's body for telemetric powering and signal reading with respect to the sensor. In an alternative embodiment, the sensor has a tapered distal end and a tissue piercing tip for direct implantation into tissue. Alternative embodiments of this sensor include helical threads on the tapered distal end for threading the sensor into tissue and a plurality of tissue barbs for direct and firm anchoring of the sensor in tissue.

    Hybrid magnetic-based and impedance-based position sensing
    7.
    发明授权
    Hybrid magnetic-based and impedance-based position sensing 有权
    基于混合磁性和基于阻抗的位置检测

    公开(公告)号：US07536218B2

    公开(公告)日：2009-05-19

    申请号：US11182272

    申请日：2005-07-15

    申请人： Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

    发明人： Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

    IPC分类号： A61B5/05

    CPC分类号： A61B5/063 ,  A61B5/0035 ,  A61B5/0538

    摘要： A position sensing system includes a probe adapted to be introduced into a body cavity of a subject. The probe includes a magnetic field transducer and at least one probe electrodes. A control unit is configured to measure position coordinates of the probe using the magnetic field transducer. The control unit also measures an impedance between the at least one probe electrodes and one or more points on a body surface of the subject. Using the measured position coordinates, the control unit calibrates the measured impedance.

    摘要翻译： 位置感测系统包括适于被引入被检体体腔的探头。 探头包括磁场换能器和至少一个探针电极。 控制单元被配置为使用磁场换能器来测量探头的位置坐标。 控制单元还测量至少一个探针电极与被检体的身体表面上的一个或多个点之间的阻抗。 使用测量的位置坐标，控制单元校准测量的阻抗。

    Externally applied RF for pulmonary vein isolation
    8.
    发明授权
    Externally applied RF for pulmonary vein isolation 有权
    外部应用RF用于肺静脉隔离

    公开(公告)号：US07367970B2

    公开(公告)日：2008-05-06

    申请号：US10706299

    申请日：2003-11-11

    申请人： Assaf Govari ,  Yitzhack Schwartz

    发明人： Assaf Govari ,  Yitzhack Schwartz

    IPC分类号： A61B18/18

    CPC分类号： A61B18/14 ,  A61B2017/00004 ,  A61B2018/00375

    摘要： A resonant circuit is incorporated in a stent, which implantable in a pulmonary vein using known cardiac catheterization techniques. When an external RF field is generated at the resonant frequency of the stent, RF energy is re-radiated by the stent toward electroconductive tissue in the wall of the pulmonary vein, and produces a circumferential conduction block. The stent can be made of biodegradable materials, so that it eventually is resorbed. Following an ablation procedure, the stent may be left in situ. Repeated ablation can be performed using the inserted stent until it has been determined that the desired lesions have been formed. Furthermore, the same stent can potentially be used even years after being inserted should the treated arrhythmia reoccur or a new arrhythmia develop, thereby possibly obviating the need for an invasive procedure at that future time.

    摘要翻译： 谐振电路并入支架中，其可以使用已知的心脏导管插入技术植入肺静脉。 当在支架的共振频率处产生外部RF场时，RF能量被支架重新辐射到肺静脉壁中的导电组织，并产生周向传导阻滞。 支架可以由可生物降解的材料制成，使其最终被吸收。 在消融手术之后，支架可以留在原位。 可以使用插入的支架进行重复消融，直到确定已经形成所需的损伤为止。 此外，如果治疗的心律失常复发或新的心律失常发展，则在插入后几年可以使用相同的支架，从而可能消除在未来时间对侵入性手术的需要。

    Hybrid magnetic-base and impedance-based position sensing
    10.
    发明授权
    Hybrid magnetic-base and impedance-based position sensing 有权
    基于混合磁性和基于阻抗的位置检测

    公开(公告)号：US07848789B2

    公开(公告)日：2010-12-07

    申请号：US12425778

    申请日：2009-04-17

    申请人： Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

    发明人： Assaf Govari ,  Andres Claudio Altmann ,  Yitzhack Schwartz ,  Yaron Ephrath

    IPC分类号： A61B5/05

    CPC分类号： A61B5/063 ,  A61B5/0035 ,  A61B5/0538

    摘要： A position sensing system includes a probe adapted to be introduced into a body cavity of a subject. The lasso-shaped probe includes a magnetic field transducer in the rigid section proximal to the flexible lasso-shaped distal section which has at least one probe electrode. A control unit is configured to measure position coordinates of the probe using the magnetic field transducer. The control unit also measures an impedance between the at least one probe electrodes and one or more points on a body surface of the subject. Using the measured position coordinates, the control unit calibrates the measured impedance and provides an indication of the deformation and deflection of the flexible lasso-shaped distal section in relation to the magnetic field transducer in the rigid proximal section.

    摘要翻译： 位置感测系统包括适于被引入被检体体腔的探头。 套索形探针包括在靠近柔性套索形远端部分的刚性部分中的磁场换能器，其具有至少一个探针电极。 控制单元被配置为使用磁场换能器来测量探头的位置坐标。 控制单元还测量至少一个探针电极与被检体的身体表面上的一个或多个点之间的阻抗。 使用测量的位置坐标，控制单元校准测量的阻抗，并提供柔性套索形远端部分相对于刚性近端部分中的磁场换能器的变形和偏转的指示。