摘要:
Disclosed is a novel use of an immunoglobulin Fc fragment, and more particularly, a pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier. The pharmaceutical composition comprising an immunoglobulin Fc fragment as a carrier remarkably extends the serum half-life of a drug while maintaining the in vivo activity of the drug at relatively high levels. Also, when the drug is a polypeptide drug, the pharmaceutical composition has less risk of inducing immune responses compared to a fusion protein of the immunoglobulin Fc fragment and a target protein, and is thus useful for developing long-acting formulations of various polypeptide drugs.
摘要:
Disclosed are a protein conjugate with improved in vivo duration and stability and the use thereof. The protein conjugate includes a physiologically active polypeptide, a non-peptide polymer and an immunoglobulin Fc fragment. Since the three components are covalently linked, the protein conjugate has extended in vivo duration and enhanced stability for the physiologically active polypeptide. The protein conjugate maintains the in vivo activity at relatively high levels and remarkably increases the serum half-life for the physiologically active polypeptide, with less risk of inducing undesirable immune responses. Thus, the protein conjugate is useful for developing long-acting formulations of various polypeptide drugs.
摘要:
The disclosed technology is in connection with an array substrate of a thin film transistor liquid crystal display (TFT-LCD) and a method for manufacturing the same, and the array substrate comprises: a base substrate; a gate line and a data line forming on the base substrate and defining a pixel region, a pixel electrode, a thin film transistor and a common electrode are formed in the pixel region; a black matrix made of conductive thin film material, the black matrix is electrically connected with the common electrode.
摘要:
An image reading apparatus includes an automatic document feeder, a first reading unit to read a first side of a document fed by the automatic document feeder and to function as a main reading unit, a second reading unit to read a second side of the document fed by the automatic document feeder; and a control unit to operate the first and second reading units in order to perform an ADF two-sided reading mode. The control unit determines a point in time when the main reading unit is changed, based on a frequency in use of the ADF two-sided reading mode, and changes the main reading unit to the second reading unit at the determined point in time.
摘要:
A developing device to prevent damage of a memory unit and poor connection between terminals of the memory unit and a main body of an image forming apparatus, by improving a mounting position of the memory unit. The developing device is removably mounted to a main body of the image forming apparatus. The memory unit includes terminals exposed through a rear side of the developing device. The memory unit is disposed closer to a power reception unit formed at one side of the developing device than to a driving force reception unit formed at an other side of the developing device.
摘要:
A thin film transistor array panel includes a source electrode and a drain electrode on an insulating substrate, an oxide semiconductor on the insulating substrate and overlapping the source electrode and the drain electrode, a passivation layer overlapping the oxide semiconductor and on the insulating substrate, a gate electrode on the passivation layer, and a pixel electrode connected to the drain electrode. The gate electrode and the pixel electrode include a same material. The oxide semiconductor is between the source electrode and the gate electrode, and between the drain electrode and the gate electrode in a cross-sectional view of the thin film transistor array panel.
摘要:
A method for automated microscopic analysis wherein the test protocol is obtained from interrogatable data affixed to each microscope slide. The method further comprises the algorithms that implement the test protocol.
摘要:
Disclosed herein are a film for insert injection molding and an insert injection molding method using the same. The film has a symmetrical structure about a thin metallic base film. Such a structure realizes superior appearance and reliability.
摘要:
An image reading apparatus capable of changing a main reading unit at an appropriate time point such that a plurality of reading units can be equally used, and a method of controlling the same. The image reading apparatus includes an automatic document feeder, a first reading unit to read a first side of a document fed by the automatic document feeder and to function as a main reading unit, a second reading unit to read a second side of the document fed by the automatic document feeder; and a control unit to change the main reading unit from the first reading unit to the second reading unit if the number of times La of usage of the first reading unit reaches a reference value. The control unit compares the number of times La of usage of the first reading unit with a predicted lifetime Lt of the first reading unit and changes the main reading unit to the second reading unit if it is determined that the number of times La of usage of the first reading unit reaches a predetermined percentage of the predicted lifetime of the first reading unit. The control unit determines whether the main reading unit is changed or not, based on frequencies of use of the first reading unit and the second reading unit.
摘要:
A compression system for an air conditioning system includes first and second compressors. The first compressor includes a first compression chamber in which a fluid introduced from an outside of the first compressor is compressed, and a first case defining a first space into which the fluid compressed in the first compression chamber is introduced. The second compressor includes a second case defining a second space into which the fluid compressed in the first compressor is introduced, and a second compression chamber in which the fluid introduced from the second space is compressed. The second compressor operates independently of the first compressor, and a connecting line connects the first and second compressors.