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公开(公告)号：US06258386B1
公开(公告)日：2001-07-10
申请号：US09362328
申请日：1999-07-28
申请人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
发明人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
IPC分类号： A61K3578
CPC分类号： A61K31/704 , A61K31/58 , G01N33/944
摘要： The invention discloses the use of a smilagenin in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
摘要翻译： 本发明公开了用于治疗认知功能障碍和类似病症的微胶原蛋白的用途。 还公开了治疗方法和药物组合物。
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公开(公告)号：US07166308B2
公开(公告)日：2007-01-23
申请号：US10691033
申请日：2003-10-21
申请人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
发明人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
IPC分类号： A61K36/8965
CPC分类号： G01N33/502 , A61K31/58 , A61K31/704 , A61K31/7048 , G01N33/5008 , G01N33/5023 , G01N33/5058 , G01N33/5061 , G01N33/5088 , G01N33/944
摘要： The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
摘要翻译： 本发明公开了用于治疗认知功能障碍和类似病症的微胶原蛋白的用途。 还公开了治疗方法和药物组合物。
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公开(公告)号：US07368137B2
公开(公告)日：2008-05-06
申请号：US11621557
申请日：2007-01-09
申请人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
发明人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
IPC分类号： A61K31/70
CPC分类号： G01N33/502 , A61K31/58 , A61K31/704 , A61K31/7048 , G01N33/5008 , G01N33/5023 , G01N33/5058 , G01N33/5061 , G01N33/5088 , G01N33/944
摘要： The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
摘要翻译： 本发明公开了用于治疗认知功能障碍和类似病症的微胶原蛋白的用途。 还公开了治疗方法和药物组合物。
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公开(公告)号：US20070191290A1
公开(公告)日：2007-08-16
申请号：US11621557
申请日：2007-01-09
申请人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
发明人： Zongqin Xia , Ian Rubin , Brian Whittle , Philip Gunning , Yaer Hu , Jonathan Brostoff , Weijun Wang
IPC分类号： A61K31/7048
CPC分类号： G01N33/502 , A61K31/58 , A61K31/704 , A61K31/7048 , G01N33/5008 , G01N33/5023 , G01N33/5058 , G01N33/5061 , G01N33/5088 , G01N33/944
摘要： The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceuical compositions are also disclosed.
摘要翻译： 本发明公开了用于治疗认知功能障碍和类似病症的微胶原蛋白的用途。 还公开了治疗方法和药物组合物。
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公开(公告)号：US20070144519A1
公开(公告)日：2007-06-28
申请号：US11642963
申请日：2006-12-21
CPC分类号： A61M16/00 , A61M16/024 , A61M2205/3561 , A61M2205/3584 , A61M2205/6018 , A61M2205/6054
摘要： Components of a CPAP or other patient ventilation apparatus have a remotely-readable identification tag encoded with component identification data. The flow generator controller 40 is programmed to receive data derived from the identification tag from a tag reader, and to adapt functions of the flow controller to coordinate with the component.
摘要翻译： CPAP或其他患者通气装置的组件具有用组件识别数据编码的可远程读取的识别标签。 流量发生器控制器40被编程为从标签读取器接收从识别标签导出的数据，并且调整流量控制器的功能以与部件协调。
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公开(公告)号：US09931428B2
公开(公告)日：2018-04-03
申请号：US14125427
申请日：2011-06-13
IPC分类号： A61K36/752 , A61L12/14 , A61K31/353 , A01N65/36 , C11D3/00 , C11D7/26
CPC分类号： A61L12/14 , A01N65/36 , A61K31/353 , A61K36/752 , C11D3/0078 , C11D7/267
摘要： The present invention relates to compositions and methods for eye and contact lens care. More particularly, the invention relates to ophthalmic compositions which contain at least one bioflavonoid component for ocular care, preserving ophthalmic solutions and/or disinfecting contact lenses.
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公开(公告)号：US20080083412A1
公开(公告)日：2008-04-10
申请号：US11902509
申请日：2007-09-21
申请人： Robert Henry , Philip Kwok , Philip Gunning , Karthikeyan Selvarajan , James Morrison , Paul Green , Chripstopher Blunsden , Gregory Peake , Christopher Baxter
发明人： Robert Henry , Philip Kwok , Philip Gunning , Karthikeyan Selvarajan , James Morrison , Paul Green , Chripstopher Blunsden , Gregory Peake , Christopher Baxter
IPC分类号： A62B18/08
CPC分类号： A62B18/084 , A61M16/0683 , A61M2205/0216 , A61M2205/0227 , A61M2205/0283 , A61M2205/14 , A61M2205/583
摘要： Headgear for a patient interface includes at least one headgear strap and an indicator provided to the at least one headgear strap structured to indicate attainment of a desired adjustment setting of the headgear in response to headgear tension applied to the at least one headgear strap.
摘要翻译： 用于患者界面的头带包括至少一个头带和指示器，所述指示器被提供到所述至少一个头带，所述至少一个头带被构造成响应于施加到所述至少一个头带上的头带张力来指示达到所述头带的期望调节设置。
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公开(公告)号：US20060041119A1
公开(公告)日：2006-02-23
申请号：US10531086
申请日：2003-04-28
申请人： Philip Gunning , Peter Tiffin
发明人： Philip Gunning , Peter Tiffin
IPC分类号： C07J71/00
CPC分类号： C07J71/0005
摘要： A method to stereospecifically prepare a steroidal sapogenin or a derivative thereof by reducing a 3-keto,5β-H steroidal sapogenin with a hindered organoborane or an organo-aluminium hydride. A 3β-hydroxy,5β-H steroidal sapogenin or derivative thereof may be prepared by reducing the 3-keto,5β-H steroidal sapogenin using as reducing agent a relatively highly hindered organoborane reagent or by SN 2 inversion of a 3α-hydroxy,5β-H steroidal sapogenin or derivative thereof. The organo-aluminium hydride may be used to prepare a 3α,5β-H steroidal sapogenin or derivative thereof. The invention provides a convenient route to useful steroidal sapogenins such as sarsasapogenin, episarsasapogenin, smilagenin, epismilagenin and esters thereof, from readily available or easily preparable starting materials (e.g. diosgenone, preparable from diosgenin).
摘要翻译： 通过用受阻的有机硼烷或有机氢化铝还原3-酮基，5β-H甾体皂苷元，立体选择性地制备甾体皂苷元或其衍生物的方法。 可以通过使用相对高度受阻的有机硼烷试剂的还原剂或通过3α-羟基，5β的SN 2反转来还原3-酮基，5β-H甾体皂苷元来制备3β-羟基，5β-H甾体皂苷元或其衍生物 -H甾体皂苷元或其衍生物。 有机铝氢化物可用于制备3α，5β-H甾体皂苷元或其衍生物。 本发明提供了从易得的或易于制备的起始物质（例如，由薯os皂苷配制的脱水梭子），可用于甾体皂苷元的方便途径，例如萨洒皂草配基，季节调节素，镰刀菌素，epismilagenin及其酯。
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公开(公告)号：US20140255332A1
公开(公告)日：2014-09-11
申请号：US14239288
申请日：2012-08-24
申请人： Francesca Crawford , Philip Gunning
发明人： Francesca Crawford , Philip Gunning
IPC分类号： A61K31/79
CPC分类号： A61K31/79 , A61K9/0048 , A61K33/18 , A61K47/38 , A61K2300/00
摘要： There is provided inter alia a germicidal aqueous formulation, suitable for use in the eye, which has a pH of from 4.0 to 6.5 and which comprises 4.0 to 7.5% w/w of povidone-iodine and a viscosity increasing agent, the formulation buffered with a buffer concentration of 25 mM to 75 mM.
摘要翻译： 特别提供适用于眼睛的杀菌含水制剂，其具有4.0至6.5的pH，并且其包含4.0至7.5重量％的聚维酮碘和增粘剂，所述制剂用 缓冲液浓度为25mM至75mM。
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公开(公告)号：US20080047560A1
公开(公告)日：2008-02-28
申请号：US11878933
申请日：2007-07-27
申请人： Lee Veliss , Philip Kwok , Philip Gunning , Robert Henry , Gregory Peake , Bruce Gregory , Clive Solari , Scott Brackenreg , Karthikeyan Selvarajan
发明人： Lee Veliss , Philip Kwok , Philip Gunning , Robert Henry , Gregory Peake , Bruce Gregory , Clive Solari , Scott Brackenreg , Karthikeyan Selvarajan
IPC分类号： A62B18/08
CPC分类号： A61M16/06 , A61M16/0605 , A61M16/0666 , A61M16/0683 , A61M16/0694 , A61M16/0833 , A61M2205/0227 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/588 , A61M2210/0618 , A61M2210/0625 , H04R1/1083 , H04R5/0335
摘要： A patient interface includes a sealing arrangement adapted to provide an effective seal with the patient's nose, an inlet conduit arrangement adapted to deliver breathable gas to the sealing arrangement, and a cover that substantially encloses the sealing arrangement and/or the inlet conduit arrangement.
摘要翻译： 患者界面包括适于提供与患者鼻部的有效密封的密封装置，适于将可渗透气体输送到密封装置的入口导管装置，以及基本上封闭密封装置和/或入口导管装置的盖。
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