公开(公告)号：US5454372A

公开(公告)日：1995-10-03

申请号：US261506

申请日：1994-06-17

申请人： Zoran B. Banjanin ,  Varaz Shahmirian

发明人： Zoran B. Banjanin ,  Varaz Shahmirian

IPC分类号： G01P5/00 ,  A61B8/06 ,  G01P13/00 ,  G01S7/524 ,  G01S15/58 ,  G01S15/89 ,  G06T1/00 ,  A61B8/00

CPC分类号： G01S15/8927 ,  G01S15/582 ,  G01S15/8984 ,  G01S15/8918 ,  G01S15/8979

摘要： Method for providing a blood flow velocity display of blood flow in a blood vessel in an ultrasound imaging system by converting spectral Doppler mode data using estimates of blood flow angle and blood flow velocity. In particular, an embodiment of a first aspect of the present invention is a method which includes the steps of: (a) transmitting an acoustic beam to a region of interest in the blood vessel from a first sub-aperture array in a transducer array; (b) receiving a first echo beam from the region of interest at the first sub-aperture array, which first echo beam is generated by the acoustic beam, and a second echo beam from the region of interest at a second sub-aperture array, which second echo beam is generated by the acoustic beam; (c) estimating a first mean Doppler frequency from the first echo beam substantially in parallel with the step of estimating a second mean Doppler frequency from the second echo beam, both steps of estimating utilizing an auto-correlation algorithm; (d) estimating the angle of blood flow and blood flow velocity in the region of interest in the blood vessel from the first and second mean Doppler frequencies; (e) obtaining data to provide a spectral Doppler mode display; (f) converting the dam to provide a blood flow velocity distribution; and (g) displaying the blood flow velocity distribution along with the estimated blood flow angle.

摘要翻译： 用于通过使用血流角度和血流速度的估计转换频谱多普勒模式数据来在超声成像系统中提供血流在血流中的血流速度显示的方法。 特别地，本发明的第一方面的实施例是一种方法，其包括以下步骤：（a）从换能器阵列中的第一子孔阵列将声束传输到血管中的感兴趣区域; （b）从所述第一子孔径阵列处的所述感兴趣区域接收第一回波束，所述第一回波束由所述声波束产生，以及来自所述感兴趣区域的第二回波束在第二子孔径阵列处， 第二回波束由声束产生; （c）基本上与从第二回波束估计第二平均多普勒频率的步骤估计来自第一回波束的第一平均多普勒频率，两个步骤使用自相关算法进行估计; （d）从第一和第二平均多普勒频率估计血管中感兴趣区域中的血流角度和血流速度; （e）获得数据以提供频谱多普勒模式显示; （f）转换大坝以提供血流速度分布; 和（g）显示血流速度分布以及估计的血流角度。

公开(公告)号：US08568356B2

公开(公告)日：2013-10-29

申请号：US13039259

申请日：2011-03-02

申请人： Ronald J. Lebel ,  Varaz Shahmirian ,  Daniel Villegas ,  David Choy ,  Philip T. Weiss ,  Paul Meadows

发明人： Ronald J. Lebel ,  Varaz Shahmirian ,  Daniel Villegas ,  David Choy ,  Philip T. Weiss ,  Paul Meadows

IPC分类号： A61M37/00 ,  A61K9/22

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

公开(公告)号：US06758810B2

公开(公告)日：2004-07-06

申请号：US09768209

申请日：2001-01-22

申请人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Philip T. Weiss ,  John T. Armstrong ,  Robert C. Dennard ,  John D. Richert

发明人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Philip T. Weiss ,  John T. Armstrong ,  Robert C. Dennard ,  John D. Richert

IPC分类号： A61B500

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： An implanted medical device (e.g. infusion pump) and external device communicate with one another via telemetry wherein messages are transmitted under a robust communication protocol. The communication protocol gives enhanced assurance concerning the integrity of messages that impact medical operations of the implantable device. Messages are transmitted using a multipart format that includes a preamble, a frame sync, a telemetry ID, data, and a validation code. The data portion of the message includes an op-code that dictates various other elements that form part of the message. The data portion may also include additional elements such as sequence numbers, bolus numbers, and duplicate data elements. A telemetry ID for the transmitting device may be implicitly embedded in the message as part of the validation code that is sent with the message and that must be pre-known by the receiver to confirm the integrity of the received message.

公开(公告)号：US06635014B2

公开(公告)日：2003-10-21

申请号：US09768045

申请日：2001-01-22

申请人： Timothy J. Starkweather ,  Ronald J. Lebel ,  Varaz Shahmirian ,  Philip T. Weiss

发明人： Timothy J. Starkweather ,  Ronald J. Lebel ,  Varaz Shahmirian ,  Philip T. Weiss

IPC分类号： A61B500

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： An implanted medical device (e.g. infusion pump) and handheld communication device wherein the implantable device is capable of operating under control of different software programs, wherein a first program operates after resetting the implantable device and is not capable of providing significant medical functionality but is capable of selected telemetry operations including telemetry operations that allow replacement software to be downloaded, and wherein a second program may be caused to take control of the device and is capable of significant medical functionality and selected telemetry operations but is incapable of receiving replacement software. A software image may be received in multiple messages where each message is provided with its own validation code and wherein a validation code for the whole image is provided and wherein each provided validation code must compared to a derived validation code prior to accepting the validity of the replacement software.

摘要翻译： 植入医疗装置（例如输液泵）和手持通信装置，其中可植入装置能够在不同软件程序的控制下操作，其中第一程序在复位可植入装置之后运行，并且不能提供重要的医疗功能，但是能够 选择的遥测操作，包括允许下载替换软件的遥测操作，并且其中可以引起第二程序来控制该设备，并且能够进行重大的医疗功能和选择的遥测操作，但是不能接收替换软件。 可以在多个消息中接收软件图像，其中每个消息被提供有其自己的验证码，并且其中提供整个图像的验证码，并且其中每个提供的验证码必须在接受所述验证码的有效性之前与导出的验证码进行比较 更换软件。

公开(公告)号：US08622954B2

公开(公告)日：2014-01-07

申请号：US12769590

申请日：2010-04-28

申请人： Varaz Shahmirian ,  Wayne A. Morgan ,  Sheldon B. Moberg ,  Cary D. Talbot ,  Arthur A. Campbell ,  Jay A. Yonemoto

发明人： Varaz Shahmirian ,  Wayne A. Morgan ,  Sheldon B. Moberg ,  Cary D. Talbot ,  Arthur A. Campbell ,  Jay A. Yonemoto

IPC分类号： A61M31/00 ,  A61B5/00

CPC分类号： A61M5/1723 ,  A61M5/14276 ,  A61M2005/1405 ,  A61M2005/14208 ,  A61M2205/3507 ,  A61M2205/3523 ,  G06F19/00 ,  G06F19/3468

摘要： A relay device transfers information between a sensor system, which measures a physiological characteristic level of a user, and a fluid delivery system, which infuses a fluid into a user. The relay device includes a sensor system receiver for receiving communications from the sensor system in a sensor system format. The relay device also includes a processor for processing the communications from the sensor system and converting the communications for transmission in a delivery system format. The relay device further includes a delivery system transmitter for transmitting the converted communications in the delivery system format to the fluid delivery system. The sensor system and delivery system formats may utilize different frequencies and/or different communication protocols for communications transmitted between the sensor system and the fluid delivery system through the relay device.

摘要翻译： 中继装置在测量用户的生理特征水平的传感器系统和将流体注入用户之间的流体输送系统之间传送信息。 所述中继装置包括用于以传感器系统格式从所述传感器系统接收通信的传感器系统接收器。 中继设备还包括处理器，用于处理来自传感器系统的通信，并以传送系统格式转换通信以进行传输。 中继装置还包括一个传送系统发射器，用于将传送系统格式的转换的通信传送到流体输送系统。 传感器系统和传送系统格式可以利用不同的频率和/或不同的通信协议，用于通过中继设备在传感器系统和流体传送系统之间传输的通信。

公开(公告)号：US20100191086A1

公开(公告)日：2010-07-29

申请号：US12758379

申请日：2010-04-12

申请人： Cary D. Talbot ,  John J. Mastrototaro ,  Rajiv Shah ,  Edward Chernoff ,  John C. Mueller, JR. ,  Varaz Shahmirian ,  Richard E. Purvis ,  Wayne A. Morgan ,  Rebecca K. Gottlieb

发明人： Cary D. Talbot ,  John J. Mastrototaro ,  Rajiv Shah ,  Edward Chernoff ,  John C. Mueller, JR. ,  Varaz Shahmirian ,  Richard E. Purvis ,  Wayne A. Morgan ,  Rebecca K. Gottlieb

IPC分类号： A61B5/145

CPC分类号： A61B5/0002 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/412 ,  A61B2560/0209 ,  A61B2560/0443 ,  A61B2560/0456

摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.

公开(公告)号：US07727148B2

公开(公告)日：2010-06-01

申请号：US11980149

申请日：2007-10-30

申请人： Cary D. Talbot ,  John J. Mastrototaro ,  Rajiv Shah ,  Edward Chernoff ,  John C. Mueller, Jr. ,  Varaz Shahmirian ,  Richard E. Purvis ,  Wayne A. Morgan ,  Rebecca K. Gottlieb

发明人： Cary D. Talbot ,  John J. Mastrototaro ,  Rajiv Shah ,  Edward Chernoff ,  John C. Mueller, Jr. ,  Varaz Shahmirian ,  Richard E. Purvis ,  Wayne A. Morgan ,  Rebecca K. Gottlieb

IPC分类号： A61B5/00

CPC分类号： A61B5/0002 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/412 ,  A61B2560/0209 ,  A61B2560/0443 ,  A61B2560/0456

摘要： A system is provided for sensing blood glucose data of a patient. The system includes a sensor, user interface, and an optional auxiliary device. If the connection between the sensor and user interface is by a wire, the sensor remains powered when the wire is disconnected. The communication between the sensor and the user interface may be wireless. The auxiliary device can be a patient monitor or other display or signal device, which displays information about the blood glucose data collected by the sensor. The sensor is connected to sensor electronics, which include a sensor power supply, a voltage regulator, and optionally a memory and processor.

摘要翻译： 提供了一种用于感测患者血糖数据的系统。 该系统包括传感器，用户界面和可选的辅助设备。 如果传感器和用户界面之间的连接是通过导线连接的，那么当导线断开时，传感器保持供电。 传感器和用户界面之间的通信可能是无线的。 辅助装置可以是患者监视器或其他显示器或信号装置，其显示关于由传感器收集的血糖数据的信息。 传感器连接到传感器电子设备，其中包括传感器电源，电压调节器以及可选的存储器和处理器。

公开(公告)号：US06585644B2

公开(公告)日：2003-07-01

申请号：US09768203

申请日：2001-01-22

申请人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Philip T. Weiss ,  Daniel H. Villegas ,  Robert C. Dennard ,  John T. Armstrong ,  John D. Richert

发明人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Philip T. Weiss ,  Daniel H. Villegas ,  Robert C. Dennard ,  John T. Armstrong ,  John D. Richert

IPC分类号： A61B500

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： An implanted medical device (e.g. infusion pump) and an external device communicate with one another via telemetry messages that are receivable only during windows or listening periods. Each listening period is open for a prescribed period of time and is spaced from successive listening periods by an interval. The prescribed period of time is typically kept small to minimize power consumption. To increase likelihood of successful communication, the window may be forced to an open state, by use of an attention signal, in anticipation of an incoming message. To further minimize power consumption, it is desirable to minimize use of extended attention signals, which is accomplished by the transmitter maintaining an estimate of listening period start times and attempting to send messages only during listening periods. In the communication device, the estimate is updated as a result of information obtained with the reception of each message from the medical device.

摘要翻译： 植入式医疗装置（例如输液泵）和外部装置通过仅在窗口或收听期间可接收的遥测信息相互通信。 每个聆听期间开放一段规定的时间段，并且与连续的收听周期间隔一段间隔。 规定的时间段通常保持较小以最小化功耗。 为了增加成功通信的可能性，可以通过使用注意信号将窗口强制为打开状态，以预期传入的消息。 为了进一步最小化功率消耗，期望最小化延长的注意信号的使用，其由发射机维持听觉周期开始时间的估计并且仅在听音周期期间尝试发送消息来实现。 在通信装置中，作为来自医疗装置的每个消息的接收获得的信息的结果，更新估计。

公开(公告)号：US06562001B2

公开(公告)日：2003-05-13

申请号：US09768044

申请日：2001-01-22

申请人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Daniel H. Villegas ,  Philip T. Weiss

发明人： Ronald J. Lebel ,  Varaz Shahmirian ,  Timothy J. Starkweather ,  Daniel H. Villegas ,  Philip T. Weiss

IPC分类号： A61M3100

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： An implantable infusion pump possesses operational functionality that is, at least in part, controlled by software operating in two processor ICs which are configured to perform some different and some duplicate functions. The pump exchanges messages with an external device via telemetry. Each processor controls a different part of the drug infusion mechanism such that both processors must agree on the appropriateness of drug delivery for infusion to occur. Delivery accumulators are incremented and decremented with delivery requests and with deliveries made. When accumulated amounts reach or exceed, quantized deliverable amounts, infusion is made to occur. The accumulators are capable of being incremented by two or more independent types of delivery requests. Operational modes of the infusion device are changed automatically in view of various system errors that are trapped, various system alarm conditions that are detected, and when excess periods of time lapse between pump and external device interactions.

公开(公告)号：US20110275904A1

公开(公告)日：2011-11-10

申请号：US13039259

申请日：2011-03-02

申请人： Ronald J. Lebel ,  Varaz Shahmirian ,  Daniel H. Villegas ,  David Y. Choy ,  Philip T. Weiss ,  Paul M. Meadows

发明人： Ronald J. Lebel ,  Varaz Shahmirian ,  Daniel H. Villegas ,  David Y. Choy ,  Philip T. Weiss ,  Paul M. Meadows

IPC分类号： A61M5/172 ,  A61M5/142 ,  H01R43/00 ,  A61B5/00

CPC分类号： A61M5/172 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/6847 ,  A61B2560/0209 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/168 ,  A61M5/16831 ,  A61M2005/14208 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/6018 ,  A61M2205/8206 ,  A61M2207/00 ,  A61N1/37211 ,  A61N1/37247 ,  A61N1/37252 ,  A61N1/37258 ,  A61N1/37264 ,  A61N1/3727 ,  A61N1/37276 ,  A61N1/375 ,  G06F3/0619 ,  G06F3/065 ,  G06F3/0673 ,  G06F8/60 ,  G06F8/65 ,  G06F19/00 ,  G06F19/3468 ,  G06Q50/22 ,  G16H40/40 ,  Y02D10/42 ,  Y10S128/13 ,  Y10S128/903 ,  Y10T29/49117 ,  Y10T29/49826

摘要： A communication device (CD) exchanges messages with an implantable infusion pump via telemetry such that commands are supplied thereto and operational information is obtained therefrom. The CD is controlled, at least in part, by a processor IC according to a software program operating therein and provides feedback to a user via a visual display, an audio alarm, and a vibrational alarm, and allows input from the user via a touch sensitive keypad. Certain input functions are restricted by password. The visual display includes an icon and fixed element display region and a bitmap display region. The fixed element display region includes time and date displays, battery and drug level displays that decrement, and a moving delivery state display. Various screens allow operational or log information to be displayed and/or user entry of commands. Program features when disabled are removed from a series of screen options that can be scrolled through.

摘要翻译： 通信设备（CD）通过遥测与可植入输液泵交换消息，从而向其提供命令并获得操作信息。 CD至少部分地由处理器IC根据其中操作的软件程序进行控制，并通过视觉显示，音频报警和振动报警向用户提供反馈，并允许用户通过触摸进行输入 敏感键盘。 某些输入功能受密码限制。 视觉显示器包括图标和固定元件显示区域和位图显示区域。 固定元件显示区域包括时间和日期显示，递减的电池和药物水平显示以及移动的传送状态显示。 各种屏幕允许显示操作或日志信息和/或用户输入命令。 禁用时的程序功能从可以滚动的一系列屏幕选项中删除。