摘要:
Process for obtaining an enantiomerically enriched N-acylazetidine-2-carboxylic acid, wherein a racemic N-acylazetidine-2-carboxylic acid ester is contacted with an enzyme that displays enantiospecificity to form enantiomerically enriched N-acylazetidine-2-carboxylic acid.
摘要:
The present invention relates to a spray mouthpiece arranged on the outer free end of a spray tube. The mouthpiece is adapted by means of intersecting flow passages to atomize liquid which is fed to the spray tube under pressure. The arrangement according to the invention comprises an elongated sleeve which is adapted to be carefully placed on the free end of the spray tube. The sleeve is designed with an end face on which is a centrally located mouthpiece opening. In the sleeve is a cylindrical body connecting to the end face. The body has grooves with which the sleeve forms at least two ducts communicating with the tube. From the tube end, the ducts run approximately axially up to the end face. By means of the intersecting flow passages formed on the end face of the body, the ducts are connected to a chamber that connects to the mouthpiece opening.
摘要:
A process for the preparation of 14-alkoxyindolomorphinans and 14-alkoxybenzofuranomorphinans is disclosed. The process facilitates the preparation of a large variety of 14-alkoxy substituted indolomorphinans and benzofuranomorphinans in which a 3-hydroxy substituent is present.
摘要:
A new pharmaceutical preparation comprising one or more local anaesthetic agents, a polar lipid, a triacylglycerol and optionally water. The new pharmaceutical preparation is excellent for topical treatment of pain.
摘要:
Compounds of the formula I ##STR1## as well as methods for their preparation, their pharmaceutical preparations and their use in therapy, especially as analgesics and as immunosuppressive agents.
摘要:
Compounds of formula (I) ##STR1## in which R.sub.1 is hydrogen, R.sub.2 is hydrogen or C.sub.1-6 alkyl, R.sub.3 and R.sub.4 independently represent one or more radicals selected from hydrogen, NH.sub.2, NO.sub.2, halogen, hydroxy, C.sub.1-6 alkoxy or C.sub.1-6 alkyl, X represents S or --CH.dbd.CH-- group and pharmaceutically acceptable salts are NMDA receptor antagonists.
摘要:
A container which is at least partially filled with a liquid is centrifuged while its longitudinal axis is maintained substantially perpendicular to its axis of rotation thereby causing impurities which may be present in the liquid to move to the end of the container farthest from the axis of rotation while the air bubbles in the liquid collect at the end of the container nearest to the axis of rotation. The container is then moved diametrically past the axis of rotation causing the air to move to the opposite end of the container. The centrifuging of the container continues causing any impurities which may be present to be transferred from the end of the container in which they have been collected to the opposite end. The presence or absence of these impurities is sensed by a photoelectric device during this transfer.
摘要:
NEW A-PHENYL-A-ALKYLSUCCINIMIDES SUBSTITUTED AT THE NITROGEN ATOM WITH AN ALKYLAMINOALKYL GROUP ARE DISCLOSED WHICH ARE EFFECTIVE AS LOCAL ANESTHETICS.