公开(公告)号：US20210039241A1

公开(公告)日：2021-02-11

申请号：US16985878

申请日：2020-08-05

申请人： Roehm GmbH

发明人： Hans BAUMANN ,  Peter SCHENK ,  Stefan KEMPTER

IPC分类号： B25F3/00 ,  B25F5/02

摘要： A hand-held machine tool having a machine spindle rotatably mounted in a machine housing, in which a control member and at least one locking member are mounted so as to be radially adjustable and are adjustable between a change position and a locking position by means of an adjusting sleeve guided on the machine spindle in such a way that, when adjusting the adjusting sleeve to the change position, the control member is acted upon radially inward by the adjusting sleeve and the locking member is not acted upon by the adjusting sleeve, that when adjusting the adjusting sleeve to the locking position, the locking member is acted upon by the adjusting sleeve, and that an adjusting ring mounted on the machine housing for adjusting the adjusting sleeve is provided between the change position and the locking position.

公开(公告)号：US10596539B2

公开(公告)日：2020-03-24

申请号：US16095065

申请日：2017-04-13

申请人： Evonik Roehm GmbH

发明人： Alexander Lygin ,  Matthias Groemping ,  Steffen Krill

IPC分类号： C07C67/00 ,  B01J8/00 ,  B01J8/22 ,  C07C67/39 ,  B01J8/18

摘要： A process for performing a heterogeneously catalysed reaction in a three-phase reactor, where there is at least one liquid phase, at least one gaseous phase and at least one solid phase in the reactor and the reactor has at least two zones, with the reaction mixture being conveyed downward in zone 1, the reaction mixture being conveyed upward in zone 2, zones 1 and 2 being separated from one another by a dividing wall, and in that the ratio between the average catalyst concentrations in zone 2 and in zone 1 is greater than 2.

公开(公告)号：US10322169B2

公开(公告)日：2019-06-18

申请号：US15735161

申请日：2016-06-06

申请人： Evonik Roehm GmbH

发明人： Juan Tome-Alcalde ,  Norbert Windhab ,  Melanie Liefke ,  Anne Benedikt ,  Jessica Müller-Albers ,  Tom Tice ,  Susanne Ullrich ,  Andrea Engel ,  Matthias Germer ,  Steffen Kistner ,  Jens Daufenbach

IPC分类号： A61K38/00 ,  A61K38/36 ,  A61K9/16 ,  A61K9/19 ,  A61K38/48 ,  A61K38/49 ,  A61K47/34 ,  A61K9/51

摘要： A process for preparing a powder, which includes one or more human coagulation factor proteins and a lactic acid polymer, involves mixing and dispersing a lactic acid polymer with a particle size d50 in the range 0.1-2 μm and the one or more human coagulation factor proteins in water. The dispersion is dried, and the resulting dried mass is compressed. The resulting compressed dried mass is comminuted to a powder with a particle size d50 in the range of more than 0.5 and up to 5 μm.

公开(公告)号：US20190112255A1

公开(公告)日：2019-04-18

申请号：US16161395

申请日：2018-10-16

申请人： Evonik Roehm GmbH

发明人： Steffen KRILL ,  Torsten BALDUF ,  Martin KOESTNER ,  Matthias GROEMPING ,  Alexander LYGIN ,  Rudolf BURGHARDT

IPC分类号： C07C67/39 ,  C07C45/75

摘要： The present invention relates to a process for producing methyl methacrylate, comprising the following steps: A) producing methacrolein and B) reacting the methacrolein obtained in step A) in an oxidative esterification reaction to give methyl methacrylate, characterized in that the two steps A) and B) take place in a liquid phase at a pressure of from 2 to 100 bar, and step B) is carried out in the presence of a heterogeneous noble-metal-containing catalyst comprising metals and/or comprising metal oxides.

公开(公告)号：US20190084914A1

公开(公告)日：2019-03-21

申请号：US16134569

申请日：2018-09-18

申请人： Evonik Roehm GmbH

发明人： Steffen Krill ,  Marcel Treskow

IPC分类号： C07C67/44 ,  C07C69/54 ,  B01J23/80 ,  B01J23/52 ,  B01J21/06 ,  B01J21/08 ,  B01J21/04 ,  B01J35/10 ,  B01J35/02

摘要： The present invention relates to a novel process for oxidative esterification, generally for reaction of aldehydes with alcohols in the presence of oxygenous gases directly to give the corresponding ester in the presence of a heterogeneous catalyst, by means of which, for example, (meth)acrolein can be converted to methyl (meth)acrylate. The new catalyst has titanium dioxide as the main component of the support material. The catalysts are especially notable for high mechanical and chemical stability and for good catalytic performance even over very long periods. The process is an improvement in the catalyst service life, activity and selectivity over prior art catalysts which lose activity and/or selectivity relatively quickly in continuous operation in media having even a small water content.

公开(公告)号：US10207435B2

公开(公告)日：2019-02-19

申请号：US15321845

申请日：2015-06-25

申请人： Kay Bernhard ,  Ina Liebl ,  Tim Denk ,  Florian Becker ,  Thomas Richter

发明人： Kay Bernhard ,  Ina Liebl ,  Tim Denk ,  Florian Becker ,  Thomas Richter

IPC分类号： B29C44/14 ,  B29C44/34 ,  B29C44/44 ,  C08J9/04 ,  C08J9/232 ,  B32B5/24 ,  B32B7/12 ,  B32B15/04 ,  B32B15/18 ,  B29K33/00 ,  B29L31/30

摘要： The invention relates to a process for the production of mold-foamed poly(meth)acrylimide (P(M)I) cores, in particular of polymethacrylimide (PMI) cores, which can be used by way of example in automobile construction or aircraft construction. A feature of this process is that polymer granules or polymer powder preheated under pressure are moreover charged under pressure to a compression mold where they are foamed with depressurization. In particular, a feature of the process is that it optionally uses a preferably two-shell compression mold for the heating and also for the cooling of the granules and, respectively, the rigid foam core formed therefrom.

公开(公告)号：US10165988B2

公开(公告)日：2019-01-01

申请号：US14899400

申请日：2014-06-06

申请人： EVONIK ROEHM GmbH ,  Gabriele Wersin

发明人： Benedikt Hartwig ,  Peter Niepoth ,  Hans-Joachim Stiller ,  Steffen Junginger

IPC分类号： A61B5/05 ,  A61B5/00 ,  G01R33/09 ,  G01V3/08 ,  A61J3/00

摘要： The invention relates to a device with a sensor arrangement, which is able to detect magnetic or magnetized oral administration forms after oral take-up, moreover tracks the dissolution thereof via the reduction or disappearance of the magnetic field of the oral administration form, and with a log function, which records a subjective evaluation on the part of the human wearer of the sensor arrangement during or after the oral take-up.

公开(公告)号：US20180318211A1

公开(公告)日：2018-11-08

申请号：US15776043

申请日：2016-11-11

申请人： Evonik Roehm GmbH

发明人： Norbert Windhab ,  Rima Jaber ,  Axel Schroeder ,  Kevin Burton ,  Tom Tice

IPC分类号： A61K9/00 ,  A61K47/34 ,  A61K31/536 ,  A61K47/22 ,  A61K31/505 ,  A61K45/06

CPC分类号： A61K9/0024 ,  A61K31/505 ,  A61K31/536 ,  A61K45/06 ,  A61K47/22 ,  A61K47/34 ,  A61K2300/00

摘要： An injection solution can be used in a pharmaceutical dosage formulation. The injection solution includes an organic solvent, a copolymer, which is a poly(lactide-co-glycolide) dissolved in the organic solvent, and a pharmaceutical active ingredient, which is a non-nucleoside inhibitor of the HIV reverse transcriptase or of the HIV integrase, and which contains aromatic and heterocyclic aromatic or aromatic and heterocyclic aromatic and aliphatic heterocyclic groups, where a content of the pharmaceutical active ingredient is from about 8 to about 25% by weight of the copolymer solution.

公开(公告)号：US20180201738A1

公开(公告)日：2018-07-19

申请号：US15741995

申请日：2016-06-21

申请人： EVONIK RÖHM GMBH

发明人： Andreas KIRCHNER ,  Rosario Lizio ,  Markus Rolf Rossmeissl ,  Wolfgang Luley ,  Johannes Vorholz ,  Silko Grimm ,  Marc Scheider

IPC分类号： C08J3/12 ,  C08J3/09 ,  A61K9/14 ,  A61K47/34

CPC分类号： C08J3/12 ,  A61K9/146 ,  A61K47/34 ,  C08G63/88 ,  C08J3/095 ,  C08J2367/04

摘要： A process for preparing poly(lactide-co-glycolide) copolymer particles with an average particle size in the range of 50-800 nm includes transferring a mixture of poly(lactide-co-glycolide) copolymer, ethanol and carbon dioxide from a first reactor into a second reactor under rapid reduction of the pressure and expansion with phase separation into a gas phase, an ethanol aerosol and an ethanolic suspension containing poly(lactide-co-glycolide) copolymer particles, removing the carbon dioxide gas and the ethanol aerosol from the second reactor, and obtaining the poly(glycolide-co-lactide) copolymer particles in the form of an ethanolic suspension or in dry form from the second reactor.

公开(公告)号：US09988548B2

公开(公告)日：2018-06-05

申请号：US14772618

申请日：2014-03-19

申请人： Werner Hoess ,  Victor Khrenov ,  Reiner Mueller ,  Lukas Friedrich Doessel ,  Dominic Stoerkle

发明人： Werner Hoess ,  Victor Khrenov ,  Reiner Mueller ,  Lukas Friedrich Doessel ,  Dominic Stoerkle

IPC分类号： C08L83/00 ,  C09D133/08 ,  C08F220/14 ,  C08F220/18 ,  C08F285/00 ,  C08L51/00 ,  C09D125/12 ,  C09D125/14

CPC分类号： C09D133/08 ,  C08F220/14 ,  C08F220/18 ,  C08F285/00 ,  C08L51/003 ,  C08L2207/53 ,  C09D125/12 ,  C09D125/14 ,  C08F2220/1808 ,  C08F220/40 ,  C08F2220/1825 ,  C08F212/08 ,  C08L33/12

摘要： The invention relates to a molding composition modified for impact resistance, in particular to impact-resistant PMMA with improved optical properties at elevated temperatures, to molded items obtainable therefrom, and also to the use of the molding composition and of the molded items.