公开(公告)号：US20060153165A1

公开(公告)日：2006-07-13

申请号：US11163534

申请日：2005-10-21

申请人： Timothy Beachy

发明人： Timothy Beachy

IPC分类号： H04L12/66

CPC分类号： G01F13/008 ,  G01F1/103 ,  G01F15/003 ,  G05D7/0635 ,  Y10T137/7761

摘要： The present invention provides an apparatus for dispensing fluid in preselected volumetric quantities. The apparatus comprises a valve positioned inline with a conduit holding fluid under pressure, a flow meter positioned inline with the conduit, a control unit communicatively coupled to the valve and flow meter, the control unit adapted to open and close the valve and detect data from the flow meter associated with the volume of fluid passing through the conduit, a units select switch having a plurality of preselected settings associated with a plurality of volumetric units, the units select switch communicatively coupled to the control unit, and an incrementing switch communicatively coupled to the control unit, whereby the control unit opens the valve responsive to activation of the incrementing switch thereby permitting fluid flow through the conduit until the control unit closes the valve responsive to the flow meter indicating a volume of fluid passed through the conduit substantially equal to a volumetric unit selected on the units select switch.

摘要翻译： 本发明提供一种用于以预选的体积量分配流体的装置。 该装置包括与保持压力流体的管道在线定位的阀，与导管成直角的流量计，与阀和流量计通信地连接的控制单元，该控制单元适于打开和关闭阀门，并且检测数据 所述流量计与通过所述导管的流体的体积相关联，单元选择开关具有与多个体积单元相关联的多个预选设置，所述单元选择开关通信地耦合到所述控制单元，以及递增开关，其通信地耦合到 控制单元，由此控制单元响应于递增开关的启动而打开阀门，从而允许流体流过管道，直到控制单元关闭阀门，响应于流量计，其指示通过导管的体积体积基本上等于 在单位选择开关上选择体积单位。

公开(公告)号：US20240348057A1

公开(公告)日：2024-10-17

申请号：US18498137

申请日：2023-10-31

申请人： University of South Florida

发明人： Lingling Fan ,  Zhixin Miao

IPC分类号： H02J3/38 ,  H02J13/00

CPC分类号： H02J3/381 ,  H02J13/00001 ,  H02J2300/24 ,  H02J2300/28

摘要： In some aspects, the techniques described herein relate to a method including: receiving a data stream from one or more power plants at the same location by a computing device; based on the received data stream, determining a grid impedance of the one or more power plants with respect to a grid by the computing device; based on the received data stream, determining power plant control parameters and communication delay for each of the one or more power plants; and modeling the integrated system consisting of the one or more power plants and the grid based on the determined grid impedance and the power plant control parameters by the computing device.

公开(公告)号：US20240344068A1

公开(公告)日：2024-10-17

申请号：US18622278

申请日：2024-03-29

申请人： UNIVERSITY OF SOUTH FLORIDA

发明人： Oksana Fihurka ,  Vasyl Sava ,  Juan Sanchez-Ramos

IPC分类号： C12N15/113 ,  A61K9/127 ,  A61K31/00 ,  A61K47/36 ,  A61P25/28

CPC分类号： C12N15/113 ,  A61K9/127 ,  A61K9/1278 ,  A61K31/658 ,  A61K47/36 ,  A61P25/28 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/321

摘要： Disclosed herein are siRNAs, hybrid nanoparticles comprising the siRNAs, pharmaceutical compositions comprising the same, and methods of making and using the same to treat neurological diseases and disorders.

公开(公告)号：US20240339042A1

公开(公告)日：2024-10-10

申请号：US18625692

申请日：2024-04-03

申请人： University of South Florida

发明人： John Licato ,  Antonio Vincent Laverghetta, JR.

IPC分类号： G09B7/00

CPC分类号： G09B7/00

摘要： A system is developed employing deep neural networks from natural language processing for the automatic generation of test questions (items) for educational assessments. The system includes: at least one computing device; and a non-transitory computer-readable medium with computer-executable instructions stored thereon that when executed by the at least one computing device cause the at least one computing device to: receive a plurality of items; place the items of the plurality of items in an item bank; for each item in the item bank, generate a score for at least one psychometric property of the item; sort each item in the item bank based on the generated scores; generate a prompt for an item generator based on the sorted items; receive a generated set of items from the item generator based on the generated prompt; and add at least some of the generated set of items to the item bank.

公开(公告)号：US20240337583A1

公开(公告)日：2024-10-10

申请号：US18627805

申请日：2024-04-05

申请人： UNIVERSITY OF SOUTH FLORIDA

发明人： Dmitri V. Voronine ,  Sharad Ambardar ,  Grace Binder ,  Phat Huynh ,  Dang Nguyen

IPC分类号： G01N15/14 ,  G01N15/10 ,  G01N15/1429 ,  G01N33/483 ,  G06T5/50 ,  G06T7/00

CPC分类号： G01N15/1468 ,  G01N15/1429 ,  G01N33/4833 ,  G06T5/50 ,  G06T7/0014 ,  G01N2015/1006 ,  G06T2207/10056 ,  G06T2207/20224 ,  G06T2207/30024 ,  G06T2207/30096 ,  G06T2207/30204

摘要： Methodology of Surface-Enhanced Raman Spectroscopy with the use of a rough Al substrate to image the biochemical composition of only the plasma membrane (and substantially without the contribution, to the SERS, of the contents of the inside of an imaged cell, thereby differentiating one from another) of intact cancerous cells and intact normal non-cancerous cells. The judiciously generated roughness of the Al substrate resulted in formation of many hot spots that provided a uniform membrane signal. The peak ratios of the resulting Raman signals specific to the cell-membrane only exhibited heterogeneous properties of the membrane with different lipid and protein concentrations at different spatial locations and are identified and can be used as novel cancer biomarkers. The proposed methodology may be extended to studying the nanoscale composition of lipid rafts and protein aggregates in intact biological cells.

公开(公告)号：US12102635B2

公开(公告)日：2024-10-01

申请号：US17938531

申请日：2022-10-06

申请人： University of South Florida ,  The Florida International University Board of Trustees

发明人： Robert Deschenes ,  Arunava Roy ,  Ahmed Ramadan ,  Subhra Mohapatra ,  Marcello Giulianotti

IPC分类号： A61K31/496 ,  A61P31/14

CPC分类号： A61K31/496 ,  A61P31/14

摘要： The present disclosure relates to methods of using palmitoylation inhibitors for reducing or treating enveloped virus infections.

公开(公告)号：US20240316067A1

公开(公告)日：2024-09-26

申请号：US18593135

申请日：2024-03-01

申请人： University of South Florida

发明人： Lianchun WANG

IPC分类号： A61K31/593 ,  A61K45/06

CPC分类号： A61K31/593 ,  A61K45/06

摘要： The present disclosure provides for a method of decreasing heparan sulfate expression in a subject in need thereof, the method comprising administering an inhibitor of EXT1 gene expression, wherein the inhibitor comprises a therapeutically effective amount of vitamin D. Further provided herein, is a method of treating cancer in a subject in need thereof, the method comprising administering an inhibitor of EXT1 gene expression, wherein the inhibitor comprises a therapeutically effective amount of vitamin D.

公开(公告)号：US12094360B1

公开(公告)日：2024-09-17

申请号：US16987759

申请日：2020-08-07

申请人： University of South Florida

发明人： Koundinya Kompalli ,  Corey Richard Sargent ,  John Todaro ,  Teresa N. Gore ,  Sharlene Hope Smith ,  Patricia Cecil

IPC分类号： G09B23/32

CPC分类号： G09B23/32

摘要： Disclosed are various embodiments of an apparatus for practicing a reduction procedure for treating radial head subluxation. In one example, the apparatus can include a model arm can be pivotally mounted to and supported by a stand. The model arm includes an upper member that emulates an upper arm of a human, a lower member that emulates a lower arm of a human being, and a joint that pivotally connects the upper member and the lower member. A feedback mechanism can be provided within the joint of the model arm. The feedback mechanism can be configured to provide initial resistance to downward pivoting to the lower member relative to the upper member, to provide an audible and tactile pop when the procedure is successfully performed that emulates the audible and tactile pop that occurs when a human radial head pops back into place during an actual reduction procedure.

公开(公告)号：US12089946B1

公开(公告)日：2024-09-17

申请号：US16358793

申请日：2019-03-20

申请人： UNIVERSITY OF SOUTH FLORIDA

发明人： Theresa Ann Zesiewicz ,  Kyle Brandon Reed

IPC分类号： A61B5/00

CPC分类号： A61B5/4076 ,  A61B5/4064 ,  A61B5/4824 ,  A61B5/6826 ,  A61B5/0048

摘要： In one embodiment, a system for finger-to-thumb crease testing includes a patient interface configured to attach to a thumb of a patient, the patient interface including a touch sensor configured to sense contact between a finger of the patient and the touch sensor, the touch sensor being positioned on the patient interface in a location at which it overlies a distalmost thumb crease of the thumb when the patient interface is attached, and a control module in electrical communication with the patient interface, the control module being configured to count a number of times the patient successfully taps the touch sensor with the finger.

公开(公告)号：US12088616B2

公开(公告)日：2024-09-10

申请号：US17521549

申请日：2021-11-08

申请人： University of South Florida

发明人： Ankit Shah

IPC分类号： G06F21/57 ,  G06N3/02 ,  H04L9/40 ,  H04L41/16

CPC分类号： H04L63/1433 ,  G06F21/577 ,  G06N3/02 ,  H04L41/16

摘要： A method, system, or apparatus for mitigating computer and network security deficiencies is provided in which, the method, system, or apparatus scans computer system components for finding a vulnerability, generates a Vulnerability Priority Scoring System (VPSS) score for the vulnerability based on the vulnerability, develops a vulnerability mitigation policy based on a system state comprising the VPSS score, wherein the vulnerability mitigation policy provides a best action for mitigating the vulnerability selected among one or more trained possible actions by a deep neural network, and performs the vulnerability mitigation policy based on the best action. Other aspects, embodiments, and features are also claimed and described.