公开(公告)号：US20240292739A1

公开(公告)日：2024-08-29

申请号：US18417102

申请日：2024-01-19

Applicant: ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD.

Inventor： Hyun KIM ,  Hyun-Woo KANG ,  Hong-Se OH ,  So-Mi PARK ,  Jin-Man KIM ,  Dong-Hyung LEE ,  Samuel KIM ,  Tae-Jin LEE

IPC: H10K85/60 ,  C07C211/61 ,  C07D307/91 ,  C07D333/76 ,  C09K11/06 ,  H10K50/11 ,  H10K50/15 ,  H10K50/18

CPC classification number: H10K85/633 ,  C07C211/61 ,  C07D307/91 ,  C07D333/76 ,  C09K11/06 ,  H10K85/636 ,  C07C2603/40 ,  C07C2603/86 ,  C09K2211/1003 ,  C09K2211/1018 ,  H10K50/11 ,  H10K50/156 ,  H10K50/181 ,  H10K85/622 ,  H10K85/626 ,  H10K85/6574 ,  H10K85/6576

Abstract: The present disclosure relates to an organic electroluminescent compound represented by formula 1 and an organic electroluminescent device comprising the same. By comprising an organic electroluminescent compound according to the present disclosure, it is possible to produce an organic electroluminescent device having improved current efficiency and/or lifetime properties.

公开(公告)号：US20180079711A1

公开(公告)日：2018-03-22

申请号：US15561685

申请日：2015-12-17

Applicant: SUZHOU PHARMAVAN CANCER RESEARCH CENTER CO., LTD.

Inventor： Haimei Feng ,  Rensen Zhou ,  Xiang Chen ,  Yunhui Yu ,  Qian Liu ,  Yong Li ,  Shiping Deng ,  Chuangliang Jiang

IPC: C07C225/12 ,  C07C221/00

CPC classification number: C07C225/12 ,  A61P35/00 ,  A61P37/00 ,  C07C221/00 ,  C07C2603/86 ,  C07D207/00 ,  C07D233/60 ,  C07D295/116 ,  C07D473/18

Abstract: Provided is a glaucocalyxin A derivative, or salt thereof, as represented by the formula (I), a method for preparation of said glaucocalyxin A derivative, and a use for said glaucocalyxin A derivative in preparing pharmaceuticals for fighting autoimmune diseases and tumors, e.g. difficult-to-treat diseases such as systemic lupus erythematosus, psoriasis and triple-negative breast cancer

公开(公告)号：US09795589B1

公开(公告)日：2017-10-24

申请号：US15277700

申请日：2016-09-27

Applicant: Hong Kong Baptist University

Inventor： Hongjie Zhang ,  Man Shing Ricky Wong ,  Lei Guo ,  Siu Wai Tsang ,  Kanglun Liu ,  Tongxin Zhang

IPC: A61K45/06 ,  A61K31/357 ,  C07D319/08 ,  C07C69/12 ,  C07D493/08 ,  A61K31/22

CPC classification number: A61K31/357 ,  A61K31/22 ,  C07C69/18 ,  C07C2103/86 ,  C07C2603/86 ,  C07D319/08 ,  C07D493/08

Abstract: The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. In particular, the chemical entities of such synthetic diterpene compounds in the manufacture of a medicament is for the treatment of tumors or cancers.

公开(公告)号：US09614159B2

公开(公告)日：2017-04-04

申请号：US13928788

申请日：2013-06-27

Applicant: Idemitsu Kosan Co., Ltd.

Inventor： Masahiro Kawamura

IPC: H01L51/00 ,  H01L51/50 ,  C07C15/38 ,  C09K11/06 ,  H05B33/14 ,  C09B57/00 ,  C09B1/00

CPC classification number: H01L51/0058 ,  C07C15/38 ,  C07C2603/86 ,  C09B1/00 ,  C09B57/00 ,  C09B57/001 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1088 ,  C09K2211/1092 ,  H01L51/0054 ,  H01L51/5012 ,  H05B33/14

Abstract: A fused aromatic ring derivative shown by the following formula (1): wherein Ra and Rb are independently a hydrogen atom or a substituent, p is an integer of 1 to 8 and q is an integer of 1 to 11, when p is 2 or more, plural Ras may be independently the same or different and adjacent Ras may form a ring, when q is 2 or more, plural Rbs may be independently the same or different, L1 is a single bond, or a substituted or unsubstituted divalent linking group, and Ar1 is a substituted or unsubstituted aryl group having 6 to 50 ring carbon atoms or a substituted or unsubstituted heteroaryl group having 5 to 50 ring atoms, provided that the substituent of L1, the substituent of Ar1, Ra and Rb contain no substituted or unsubstituted amino group.

公开(公告)号：US20160340273A1

公开(公告)日：2016-11-24

申请号：US14409448

申请日：2014-05-23

Applicant: TIANJIN UNIVERSITY

Inventor： Jijun ZOU ,  Xiangwen ZHANG ,  Li WANG ,  Qingfa WANG

IPC: C07C5/22 ,  B01J35/00 ,  B01J31/02

CPC classification number: C07C5/2266 ,  B01J19/123 ,  B01J31/0208 ,  B01J31/0237 ,  B01J31/0239 ,  B01J31/0271 ,  B01J31/26 ,  B01J31/34 ,  B01J31/36 ,  B01J31/38 ,  B01J35/004 ,  C07C5/2213 ,  C07C5/222 ,  C07C2521/06 ,  C07C2523/02 ,  C07C2523/06 ,  C07C2523/20 ,  C07C2523/30 ,  C07C2531/02 ,  C07C2531/26 ,  C07C2531/34 ,  C07C2531/36 ,  C07C2531/38 ,  C07C2603/86 ,  Y02P20/582 ,  C07C13/68

Abstract: The invention discloses a continuous process for producing high-pure quadricyclane, in which “a reaction-rectification integral process” or “a reaction followed by rectification process” may be employed. The two processes both use a novel composite catalyst which is obtained by loading an organic photo-sensitizer on a solid photocatalyst, and the composite catalyst has a high activity and a good stability. In the reaction-rectification integral process, the composite catalyst is used by being blended with rectification fillers or covering the rectification fillers, so as to achieve the integration of the reaction and the rectification. In the reaction followed by rectification process, the composite catalyst and the rectification fillers are placed separately from each other. The two processes achieve a relatively short residence time of reactants, produce highly-pure quadricyclane, and reduce the formation of cokes.

Abstract translation: 本发明公开了一种生产高纯四环烷的连续方法，其中可以采用“反应整流积分法”或“精馏反应”。 这两种方法都使用通过将有机光敏剂负载在固体光催化剂上获得的新型复合催化剂，并且复合催化剂具有高活性和良好的稳定性。 在反应整流积分过程中，复合催化剂与精馏填料混合使用或覆盖整流填料，以实现反应整流。 在进行精馏处理的反应中，复合催化剂和精馏填料彼此分开放置。 这两个方法实现了反应物的相对较短的停留时间，产生高纯度的四环素，并减少了焦炭的形成。

公开(公告)号：US09499709B2

公开(公告)日：2016-11-22

申请号：US13680237

申请日：2012-11-19

Applicant: Xerox Corporation

Inventor： Rina Carlini ,  Adela Goredema

IPC: C07C69/74 ,  C09D11/34 ,  C07C69/753

CPC classification number: C09D11/34 ,  C07C69/753 ,  C07C2601/14 ,  C07C2603/54 ,  C07C2603/86

Abstract: Disclosed are ester compounds of the formulae wherein Rc is alkylene, arylene, arylalkylene, or alkylarylene as further defined herein, Rd is alkylene, arylene, arylalkylene, or alkylarylene as further defined herein, and m and n are integers representing the numbers of repeat monomer units. The materials are suitable for use in inks and other applications.

公开(公告)号：US20160332877A1

公开(公告)日：2016-11-17

申请号：US15026349

申请日：2014-10-02

Applicant: DAIKIN INDUSTRIES, LTD. ,  NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

Inventor： Shoji HARA ,  Yosuke KISHIKAWA ,  Atsushi SHIRAI ,  Takashi NAMIKAWA ,  Sumi ISHIHARA

IPC: C01B7/24 ,  C07C67/333 ,  C07C67/307 ,  C07C231/12 ,  C07C45/67 ,  C07C45/63 ,  C07C41/22 ,  C07C319/20 ,  C07C209/74 ,  C07C17/361 ,  C07D309/10 ,  C07C17/354 ,  C07D493/04 ,  C07D209/10 ,  C01D3/02

CPC classification number: C01B7/24 ,  C01D3/02 ,  C01D13/00 ,  C07C17/354 ,  C07C17/361 ,  C07C41/22 ,  C07C45/63 ,  C07C45/673 ,  C07C67/307 ,  C07C67/333 ,  C07C209/74 ,  C07C231/12 ,  C07C319/20 ,  C07C2603/86 ,  C07D209/10 ,  C07D309/10 ,  C07D493/04

Abstract: An object of the present invention is to provide a novel substance that has a high reactivity as a fluorinating agent, is effectively used in various fluorination reactions, and is safely handled even in air. As the solution for achieving this object, the present invention provides a complex obtained by reacting bromine trifluoride with at least one metal halide selected from the group consisting of halogenated metals and halogenated hydrogen metals in a nonpolar solvent. This complex serves as a fluorinating agent that provides excellent fluorination performance and that is stable in air.

Abstract translation: 本发明的目的是提供作为氟化剂具有高反应性的新物质，有效地用于各种氟化反应中，并且即使在空气中也被安全地处理。 作为用于实现该目的的方案，本发明提供了一种通过在非极性溶剂中使三氟化硼与至少一种选自卤代金属和卤代氢金属的金属卤化物反应而获得的络合物。 该复合物用作提供优异的氟化性能并且在空气中稳定的氟化剂。

公开(公告)号：US09185909B2

公开(公告)日：2015-11-17

申请号：US12733750

申请日：2008-09-17

Applicant: Scott Alan Snyder ,  Steven P. Breazzano ,  Audrey G. Ross ,  Yunqing Lin ,  Alexandros L. Zografos

Inventor： Scott Alan Snyder ,  Steven P. Breazzano ,  Audrey G. Ross ,  Yunqing Lin ,  Alexandros L. Zografos

IPC: A61K31/09 ,  A61K31/05 ,  A01N31/16 ,  C07C37/00 ,  C07C37/055 ,  C07C41/18 ,  C07C41/22 ,  C07C41/24 ,  C07C41/26 ,  C07C41/30 ,  C07C49/755 ,  C07C67/04 ,  C07C67/11 ,  C07C319/14

CPC classification number: A01N31/16 ,  C07C37/00 ,  C07C37/055 ,  C07C41/18 ,  C07C41/22 ,  C07C41/24 ,  C07C41/26 ,  C07C41/30 ,  C07C49/755 ,  C07C67/04 ,  C07C67/11 ,  C07C319/14 ,  C07C2602/08 ,  C07C2603/32 ,  C07C2603/40 ,  C07C2603/86 ,  C07C2603/90 ,  C07C39/23 ,  C07C39/17 ,  C07C43/23 ,  C07C43/21 ,  C07C43/215 ,  C07C43/225 ,  C07C69/63 ,  C07C69/013 ,  C07C323/17 ,  C07C69/157

Abstract: Processes for synthesizing resveratrol-based oligomers are provided. In addition, resveratrol-based oligomer compounds free of plant extract are provided.

Abstract translation: 提供了合成基于白藜芦醇的低聚物的方法。 此外，提供了不含植物提取物的白藜芦醇低聚物化合物。

公开(公告)号：US20150291551A1

公开(公告)日：2015-10-15

申请号：US14748925

申请日：2015-06-24

Applicant: LEO Laboratories Limited

Inventor： Gunnar GRUE-SØRENSEN ,  Xifu LIANG ,  Thomas HÖGBERG ,  Kristoffer MÅNSSON ,  Per VEDSØ ,  Thomas VIFIAN

IPC: C07D333/38 ,  A61K31/42 ,  C07D307/00 ,  A61K31/365 ,  C07D249/04 ,  A61K31/4192 ,  C07D231/14 ,  A61K31/415 ,  C07D231/56 ,  A61K31/416 ,  C07D209/42 ,  A61K31/404 ,  A61K31/381 ,  C07D217/26 ,  A61K31/472 ,  C07D237/28 ,  A61K31/502 ,  C07D295/205 ,  A61K31/5375 ,  C07D265/36 ,  A61K31/538 ,  C07D261/18

CPC classification number: C07D261/18 ,  A61K31/365 ,  A61K31/381 ,  A61K31/404 ,  A61K31/415 ,  A61K31/416 ,  A61K31/4192 ,  A61K31/42 ,  A61K31/472 ,  A61K31/502 ,  A61K31/5375 ,  A61K31/538 ,  C07C271/34 ,  C07C271/36 ,  C07C271/38 ,  C07C2603/86 ,  C07D209/08 ,  C07D209/42 ,  C07D213/79 ,  C07D215/50 ,  C07D217/26 ,  C07D231/14 ,  C07D231/56 ,  C07D233/90 ,  C07D237/28 ,  C07D239/28 ,  C07D249/04 ,  C07D249/06 ,  C07D261/20 ,  C07D263/34 ,  C07D265/36 ,  C07D271/08 ,  C07D277/32 ,  C07D277/56 ,  C07D277/587 ,  C07D295/182 ,  C07D295/205 ,  C07D295/21 ,  C07D307/00 ,  C07D307/68 ,  C07D307/94 ,  C07D309/08 ,  C07D333/38 ,  C07D333/40 ,  C07D401/04 ,  C07D405/06 ,  C07D471/04 ,  C07D493/08 ,  C07D495/04 ,  C07D513/04

Abstract: The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is —NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.

Abstract translation: 本发明涉及通式I的化合物，其中R是任选被R 7取代的杂芳基; 或R是任选被R 8取代的杂环烷基或杂环烯基; 或R为X，其中X为-NR 11 R 12; 其药学上可接受的盐，水合物或溶剂合物，用于单独或与一种或多种其它药学活性化合物组合用于治疗，用于预防，治疗或改善响应刺激的中性粒细胞氧化性突发的反应的疾病或病症 的角质形成细胞IL-8释放或响应于坏死的诱导。

公开(公告)号：US20140303150A1

公开(公告)日：2014-10-09

申请号：US13996989

申请日：2011-12-22

Applicant: Gunnar Grue-Sørensen ,  Xifu Liang ,  Thomas Högberg ,  Kristoffer Månsson ,  Per Vedsø ,  Thomas Vifian

Inventor： Gunnar Grue-Sørensen ,  Xifu Liang ,  Thomas Högberg ,  Kristoffer Månsson ,  Per Vedsø ,  Thomas Vifian

IPC: C07D513/04 ,  C07D333/38 ,  C07D471/04 ,  C07D401/04 ,  C07D265/36 ,  C07D405/06 ,  C07D271/08 ,  C07D277/587 ,  C07D295/205 ,  C07D307/00 ,  C07D307/94

CPC classification number: C07D261/18 ,  A61K31/365 ,  A61K31/381 ,  A61K31/404 ,  A61K31/415 ,  A61K31/416 ,  A61K31/4192 ,  A61K31/42 ,  A61K31/472 ,  A61K31/502 ,  A61K31/5375 ,  A61K31/538 ,  C07C271/34 ,  C07C271/36 ,  C07C271/38 ,  C07C2603/86 ,  C07D209/08 ,  C07D209/42 ,  C07D213/79 ,  C07D215/50 ,  C07D217/26 ,  C07D231/14 ,  C07D231/56 ,  C07D233/90 ,  C07D237/28 ,  C07D239/28 ,  C07D249/04 ,  C07D249/06 ,  C07D261/20 ,  C07D263/34 ,  C07D265/36 ,  C07D271/08 ,  C07D277/32 ,  C07D277/56 ,  C07D277/587 ,  C07D295/182 ,  C07D295/205 ,  C07D295/21 ,  C07D307/00 ,  C07D307/68 ,  C07D307/94 ,  C07D309/08 ,  C07D333/38 ,  C07D333/40 ,  C07D401/04 ,  C07D405/06 ,  C07D471/04 ,  C07D493/08 ,  C07D495/04 ,  C07D513/04

Abstract: The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is —NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.

Abstract translation: 本发明涉及通式I的化合物，其中R是任选被R 7取代的杂芳基; 或R是任选被R 8取代的杂环烷基或杂环烯基; 或R为X，其中X为-NR 11 R 12; 其药学上可接受的盐，水合物或溶剂合物，用于单独或与一种或多种其它药学活性化合物组合用于治疗，用于预防，治疗或改善响应刺激的中性粒细胞氧化性突发的反应的疾病或病症 的角质形成细胞IL-8释放或响应于坏死的诱导。