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公开(公告)号:US20130307167A1
公开(公告)日:2013-11-21
申请号:US13882052
申请日:2011-10-26
CPC分类号: H01L23/295 , C07C39/205 , C08G8/20 , C08G8/22 , C08G59/621 , C08L63/00 , H01L23/291 , H01L23/293 , H01L2924/0002 , H01L2924/00
摘要: The present invention relates to techniques including a phenolic oligomer of general formula (1): wherein n is an integer of 0 to 15, Rs are allyl groups, a1 and a3 are each independently 0, 1, 2 or 3, each a2 is independently 0, 1 or 2, each R′ is independently a hydrogen atom, an alkyl group having 1 to 10 carbon atoms or an aryl group, and proviso that at least one of a1, each a2 and a3 represents 2, and a method for producing such phenolic oligomer.
摘要翻译: 本发明涉及包括通式(1)的酚低聚物的技术:其中n为0至15的整数,R 5为烯丙基,a1和a3各自独立地为0,1,2或3,各自独立地为 0,1或2,每个R'独立地是氢原子,具有1-10个碳原子的烷基或芳基,并且条件是a1,a2和a3中的至少一个代表2,和 这种酚类低聚物。
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公开(公告)号:US20180057444A1
公开(公告)日:2018-03-01
申请号:US15659320
申请日:2017-07-25
发明人: HONGYIN GAO , Zhe ZHOU , Laszlo KURTI
IPC分类号: C07C209/66 , C07C37/01 , C07D295/135 , C07D307/79 , C07D317/66 , C07D317/46 , C07C319/20 , C07D317/28 , C07D309/12 , C07D213/73 , C07D213/04 , C07D209/04 , C07D277/82 , C07D333/20 , C07D307/91 , C07D209/88 , C07J41/00 , C07D333/16 , C07C41/26 , C07D317/64 , C07D295/096 , C07D317/20 , C07B43/04 , C07B41/02
CPC分类号: C07C209/66 , C07B41/02 , C07B43/04 , C07C37/01 , C07C37/055 , C07C37/64 , C07C41/26 , C07C213/02 , C07C227/06 , C07C303/30 , C07C319/20 , C07C2601/02 , C07C2601/04 , C07C2601/14 , C07C2603/18 , C07C2603/26 , C07D209/04 , C07D209/88 , C07D213/04 , C07D213/73 , C07D215/38 , C07D277/82 , C07D295/096 , C07D295/135 , C07D307/79 , C07D307/91 , C07D309/12 , C07D311/58 , C07D317/20 , C07D317/28 , C07D317/46 , C07D317/64 , C07D317/66 , C07D333/16 , C07D333/20 , C07D333/36 , C07J41/0011 , C07C211/58 , C07C217/94 , C07C211/59 , C07C211/61 , C07C211/47 , C07C211/44 , C07C217/80 , C07C211/51 , C07C323/36 , C07C309/30 , C07C229/56 , C07C229/60 , C07C219/34 , C07C39/235 , C07C39/14 , C07C39/15 , C07C39/12 , C07C39/20 , C07C39/205 , C07C43/23
摘要: In one aspect, the present disclosure provides methods of preparing a primary or secondary amine and hydroxylated aromatic compounds. In some embodiments, the aromatic compound may be unsubstituted, substituted, or contain one or more heteroatoms within the rings of the aromatic compound. The methods described herein may be carried out without the need for transition metal catalysts or harsh reaction conditions.
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公开(公告)号:US10329311B1
公开(公告)日:2019-06-25
申请号:US15927264
申请日:2018-03-21
申请人: OLON S.p.A.
发明人: Federico Gassa , Lazzaro Feliciani , Alberto Mazza , Marco Quaroni , Mara Sada , Giorgio Bertolini
IPC分类号: C07F5/02 , C07C39/205 , B01J27/053 , B01J23/44 , B01J23/42 , C07C39/15 , C07C37/02 , B01J27/232
CPC分类号: C07F5/027 , B01J23/42 , B01J23/44 , B01J27/053 , B01J27/232 , C07B47/00 , C07C37/02 , C07C39/15 , C07C39/205 , C07C255/50 , C07F5/025
摘要: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
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公开(公告)号:US20190194230A1
公开(公告)日:2019-06-27
申请号:US15927264
申请日:2018-03-21
申请人: OLON S.p.A.
发明人: Federico GASSA , Lazzaro FELICIANI , Alberto MAZZA , Marco QUARONI , Mara SADA , Giorgio BERTOLINI
IPC分类号: C07F5/02 , C07C37/02 , C07C39/15 , C07C39/205 , B01J23/42 , B01J23/44 , B01J27/053 , B01J27/232
CPC分类号: C07F5/027 , B01J23/42 , B01J23/44 , B01J27/053 , B01J27/232 , C07B47/00 , C07C37/02 , C07C39/15 , C07C39/205 , C07C255/50 , C07F5/025
摘要: The present invention relates to a process for the preparation of crisaborole of formula (I): by preparing intermediates of formulas (II) and (III):
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公开(公告)号:US20080300298A1
公开(公告)日:2008-12-04
申请号:US11884989
申请日:2006-02-23
申请人: Jack L. Arbiser , Frank Amblard
发明人: Jack L. Arbiser , Frank Amblard
IPC分类号: A61K31/357 , C07C43/23 , C07C39/12 , C07C25/18 , A61K31/135 , A61K31/03 , A61P35/04 , A61K31/05 , A61K31/075 , C07C211/50 , C07D321/10
CPC分类号: C07C43/23 , C07C39/15 , C07C39/205 , C07C39/225 , C07C43/215 , C07C211/53 , C07D321/10
摘要: The present invention provides novel honokiol derivatives, as well as pharmaceutical compositions containing the honokiol derivatives. These compounds and pharmaceutical compositions can be used in the prevention and/or treatment of cancer. In particular, honokiol derivatives, pharmaceutical compositions comprising the derivatives, and methods for their use in the treatment of myeloma are provided.
摘要翻译: 本发明提供新颖的和厚朴酚衍生物,以及含有厚朴酚衍生物的药物组合物。 这些化合物和药物组合物可用于预防和/或治疗癌症。 特别地,提供和厚朴酚衍生物,包含衍生物的药物组合物,及其用于治疗骨髓瘤的方法。
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