-
1.发明申请MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF (2-HYDROXY-3METHYL-4-OXOBUTOXY) PHOSPHONATE 审中-公开（2-羟基-3-乙氧基-4-氧代氧代）磷酸酯的生物合成的微生物和方法公开(公告)号：US20150004662A1
公开(公告)日：2015-01-01
申请号：US14485040
申请日：2014-09-12
申请人： Genomatica, Inc.
发明人： Robin E. Osterhout
CPC分类号： C12N15/52 , C12N9/0006 , C12N9/1022 , C12N9/1085 , C12N9/88 , C12P7/24 , C12P7/40 , C12P7/44 , C12P7/62 , C12P9/00 , C12Y101/01025 , C12Y101/01267 , C12Y202/01007 , C12Y205/01019 , C12Y205/01054 , C12Y207/01071 , C12Y401/03 , C12Y401/0304 , C12Y402/01 , C12Y402/0101 , C12Y402/03004 , C12Y402/03005
摘要： The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway or terephthalate pathway.
摘要翻译： 本发明提供具有（2-羟基-3-甲基-4-氧代丁氧基）膦酸酯途径，对甲苯甲酸途径和/或对苯二甲酸酯途径的非天然存在的微生物生物。 本发明另外提供了使用这种生物体制备（2-羟基-3-甲基-4-氧代丁氧基）膦酸酯途径，对甲苯甲酸途径或对苯二甲酸酯途径的方法。
-
2.发明申请公开(公告)号：US20160152989A1
公开(公告)日：2016-06-02
申请号：US15016896
申请日：2016-02-05
申请人： Genomatica, Inc.
发明人： Robin E. Osterhout
CPC分类号： C12N15/52 , C12N9/0006 , C12N9/1022 , C12N9/1085 , C12N9/88 , C12P7/24 , C12P7/40 , C12P7/44 , C12P7/62 , C12P9/00 , C12Y101/01025 , C12Y101/01267 , C12Y202/01007 , C12Y205/01019 , C12Y205/01054 , C12Y207/01071 , C12Y401/03 , C12Y401/0304 , C12Y402/01 , C12Y402/0101 , C12Y402/03004 , C12Y402/03005
摘要： The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway or terephthalate pathway.
-
公开(公告)号：US20180142265A1
公开(公告)日：2018-05-24
申请号：US15867306
申请日：2018-01-10
发明人： Wendy Yiting Chen , FungMin Liew , Michael Koepke
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/1022 , C12N9/1025 , C12N9/1029 , C12N9/1085 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N15/52 , C12N15/74 , C12P7/42 , C12P9/00 , C12Y101/01088 , C12Y101/01267 , C12Y117/07001 , C12Y202/01007 , C12Y203/01009 , C12Y203/0301 , C12Y205/0101 , C12Y205/0109 , C12Y207/01036 , C12Y207/01148 , C12Y207/04002 , C12Y207/0706 , C12Y401/01033 , C12Y402/03027 , C12Y402/03046 , C12Y406/01012 , C12Y503/03002 , Y02E50/343
摘要： The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.
-
公开(公告)号：US20170283832A1
公开(公告)日：2017-10-05
申请号：US15357815
申请日：2016-11-21
发明人： Han Min WOO , Sun-young CHOI , Youngsoon UM , Gyeong Taek GONG , Sun Mi LEE , Yunje KIM
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/1022 , C12N9/1085 , C12N9/90 , C12N15/52 , C12Y101/01267 , C12Y202/01007 , C12Y205/0101 , C12Y205/01021 , C12Y503/03002
摘要： The present specification discloses a transformed Synechococcus elongatus strain which may directly produce squalene from carbon dioxide, and a method for producing squalene and a method for removing carbon dioxide, using the same. In an aspect, the strain may produce squalene using carbon dioxide as a carbon source. The Synechococcus elongatus strain is economically efficient because a high-value added squalene is produced using light and carbon dioxide present in the atmosphere as a carbon source, and the method for producing squalene is eco-friendly because the strain may be utilized to remove or reduce carbon dioxide in the atmosphere by using microorganisms. The strain of the present disclosure may produce only squalene, which is a desired target material with high purity, and has an advantage in that squalene may be continuously mass-produced.
-
公开(公告)号：US20160017374A1
公开(公告)日：2016-01-21
申请号：US14773118
申请日：2014-03-06
申请人： CALYSTA, INC.
CPC分类号： C12P5/007 , C07C11/10 , C12N9/0006 , C12N9/0093 , C12N9/1022 , C12N9/1205 , C12N9/1241 , C12N9/88 , C12N15/52 , C12Y101/01267 , C12Y117/01002 , C12Y117/07001 , C12Y207/01148 , C12Y207/0706 , C12Y402/03027 , C12Y406/01012 , Y02E50/343
摘要： The present disclosure provides compositions and methods for biologically producing isoprene using methanotrophic bacteria that utilize carbon feedstock, such as methane or natural gas.
摘要翻译： 本公开提供使用利用碳原料（例如甲烷或天然气）的甲烷营养细菌生物地生产异戊二烯的组合物和方法。
-
公开(公告)号：US20150191747A1
公开(公告)日：2015-07-09
申请号：US14656827
申请日：2015-03-13
发明人： Wendy Yiting Chen , FungMin Liew , Michael Koepke
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/1022 , C12N9/1025 , C12N9/1029 , C12N9/1085 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N15/52 , C12N15/74 , C12P7/42 , C12P9/00 , C12Y101/01088 , C12Y101/01267 , C12Y117/07001 , C12Y202/01007 , C12Y203/01009 , C12Y203/0301 , C12Y205/0101 , C12Y205/0109 , C12Y207/01036 , C12Y207/01148 , C12Y207/04002 , C12Y207/0706 , C12Y401/01033 , C12Y402/03027 , C12Y402/03046 , C12Y406/01012 , C12Y503/03002 , Y02E50/343
摘要： The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.
摘要翻译： 本发明提供了通过微生物发酵生产萜烯或其前体的方法。 通常，该方法包括在气态底物存在下培养重组细菌，由此细菌产生萜烯或其前体，例如甲羟戊酸，焦磷酸异戊烯酯，焦磷酸二甲基烯丙酯，异戊二烯，焦磷酸格那酯，和/或法呢烯 。 细菌可以包含一种或多种外源酶，例如甲羟戊酸，DXS或萜烯生物合成途径中的酶。
-
公开(公告)号：US20130323820A1
公开(公告)日：2013-12-05
申请号：US13909012
申请日：2013-06-03
发明人： Wendy Yiting Chen , FungMin Liew , Michael Koepke
IPC分类号： C12N15/74
CPC分类号： C12P5/007 , C12N9/0006 , C12N9/1022 , C12N9/1025 , C12N9/1029 , C12N9/1085 , C12N9/1205 , C12N9/1229 , C12N9/88 , C12N15/52 , C12N15/74 , C12P7/42 , C12P9/00 , C12Y101/01088 , C12Y101/01267 , C12Y117/07001 , C12Y202/01007 , C12Y203/01009 , C12Y203/0301 , C12Y205/0101 , C12Y205/0109 , C12Y207/01036 , C12Y207/01148 , C12Y207/04002 , C12Y207/0706 , C12Y401/01033 , C12Y402/03027 , C12Y402/03046 , C12Y406/01012 , C12Y503/03002 , Y02E50/343
摘要： Terpenes are valuable commercial products used in a diverse number of industries. Terpenes may be produced from petrochemical sources and from terpene feed-stocks, such as turpentine. However, these production methods are expensive, unsustainable and often cause environmental problems including contributing to climate change. Microbial fermentation provides an alternative option for the production of terpenes. One or more terpenes and/or precursors can be produced by microbial fermentation of a substrate comprising CO. Recombinant microorganisms may be used in such methods. Carboxydotrophic, acetogenic, recombinant microorganisms can be used in such methods. The recombinant microorgnsims may contain exogenous mevalonate (MVA) pathway enzymes and/or DXS pathway enzymes, for example.
摘要翻译： 萜烯是用于不同行业的有价值的商业产品。 萜烯可以由石化源和萜烯原料如松节油生产。 然而，这些生产方法是昂贵的，不可持续的，并且常常导致包括气候变化的环境问题。 微生物发酵为萜烯的生产提供了替代选择。 一种或多种萜烯和/或前体可以通过包含CO的底物的微生物发酵产生。重组微生物可以用于这些方法。 在这些方法中可以使用羧基营养型，乙酰酵素，重组微生物。 例如，重组微型蛋白可以含有外源性甲羟戊酸（MVA）途径酶和/或DXS途径酶。
-
8.发明申请MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE 审中-公开β-葡聚糖和泰乐芬酸的生物合成的微生物和方法公开(公告)号：US20110207185A1
公开(公告)日：2011-08-25
申请号：US13013704
申请日：2011-01-25
申请人： Robin E. OSTERHOUT
发明人： Robin E. OSTERHOUT
CPC分类号： C12N15/52 , C12N9/0006 , C12N9/1022 , C12N9/1085 , C12N9/88 , C12P7/24 , C12P7/40 , C12P7/44 , C12P7/62 , C12P9/00 , C12Y101/01025 , C12Y101/01267 , C12Y202/01007 , C12Y205/01019 , C12Y205/01054 , C12Y207/01071 , C12Y401/03 , C12Y401/0304 , C12Y402/01 , C12Y402/0101 , C12Y402/03004 , C12Y402/03005
摘要： The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce (2-hydroxy-3-methyl-4-oxobutoxy)phosphonate pathway, p-toluate pathway or terephthalate pathway.
摘要翻译： 本发明提供具有（2-羟基-3-甲基-4-氧代丁氧基）膦酸酯途径，对甲苯甲酸途径和/或对苯二甲酸酯途径的非天然存在的微生物生物。 本发明另外提供了使用这种生物体制备（2-羟基-3-甲基-4-氧代丁氧基）膦酸酯途径，对甲苯甲酸途径或对苯二甲酸酯途径的方法。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.019 秒)
