公开(公告)号：US11684321B2

公开(公告)日：2023-06-27

申请号：US17412734

申请日：2021-08-26

申请人： CANON MEDICAL SYSTEMS CORPORATION

发明人： Go Kawata ,  Ryo Okuda

IPC分类号： A61B6/03 ,  G01T1/16 ,  G01T1/20 ,  G01T1/22 ,  G01T1/29 ,  A61B6/00 ,  G01N23/20066 ,  G01T1/164

CPC分类号： A61B6/037 ,  A61B6/4241 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/4275 ,  A61B6/482 ,  A61B6/483 ,  A61B6/5205 ,  A61B6/5282 ,  G01N23/20066 ,  G01T1/1642 ,  G01T1/2006 ,  G01T1/2018 ,  G01T1/20181 ,  G01T1/20182 ,  G01T1/22 ,  G01T1/2907 ,  G01T1/2914 ,  G01T1/2985 ,  G01N2223/108

摘要： A radiation diagnostic device according to an aspect of the present invention includes a first detector, a second detector, and processing circuitry. The first detector detects Cherenkov light that is generated when radiation passes. The second detector is disposed to be opposed to the first detector on a side distant from a generation source of the radiation, and detects energy information of the radiation. The processing circuitry specifies Compton scattering events detected by the second detector, and determines an event corresponding to an incident channel among the specified Compton scattering events based on a detection result obtained by the first detector.

公开(公告)号：US20140205062A1

公开(公告)日：2014-07-24

申请号：US13745384

申请日：2013-01-18

申请人： Alan W. Hunt ,  J. Frank Hermon ,  Douglas P. Wells

发明人： Alan W. Hunt ,  J. Frank Hermon ,  Douglas P. Wells

IPC分类号： G01N23/223

CPC分类号： G01N23/22 ,  G01N2223/108 ,  G01N2223/646

摘要： The invention is directed to a defect imaging device that has an energy beam that is directed at a device under test. The energy beam creates positrons deep within the material of the device under test. When the positrons combine with electrons in the material they produce a pair of annihilation photons. The annihilation photons are detected. The Doppler broadening of the annihilation photons is used to determine if a defect is present in the material. Three dimensional images of the device under test are created by directing the energy beam at different portions of the device under test.

摘要翻译： 本发明涉及一种缺陷成像装置，其具有指向被测设备的能量束。 能量束在正在测试的器件的材料内部产生正电子。 当正电子与材料中的电子结合时，它们产生一对湮灭光子。 检测到湮灭光子。 湮灭光子的多普勒加宽用于确定材料中是否存在缺陷。 被测设备的三维图像通过将能量束引导到被测设备的不同部分来产生。

公开(公告)号：US09557281B2

公开(公告)日：2017-01-31

申请号：US14124654

申请日：2012-06-11

申请人： Ramsey D. Badawi ,  Kai Yang

发明人： Ramsey D. Badawi ,  Kai Yang

IPC分类号： G01N23/04 ,  A61B6/03 ,  A61B6/00 ,  G01T1/161 ,  A61B6/04

CPC分类号： G01N23/046 ,  A61B6/032 ,  A61B6/037 ,  A61B6/0407 ,  A61B6/4258 ,  A61B6/508 ,  A61B6/5235 ,  G01N2223/1016 ,  G01N2223/108 ,  G01N2223/419 ,  G01N2223/6126 ,  G01T1/161

摘要： Embodiments of the present invention provide methods and apparatus for imaging a tissue specimen excised during surgery with a combined positron emission tomography (PET) and micro computed tomography (micro CT) scanner. The specimen is scanned with a CT imaging system of the combined PET and micro CT scanner. The specimen is also scanned with a PET imaging system of the combined PET and micro CT scanner. A PET image is constructed based on data acquired by the PET imaging system. A micro CT image is constructed based on data acquired by the micro CT imaging system. The micro CT image includes at least one visualization of a lesion marker.

摘要翻译： 本发明的实施例提供了用组合正电子发射断层摄影（PET）和微型计算机断层摄影（micro CT）扫描仪对在手术期间切除的组织样本进行成像的方法和装置。 用PET和微型CT扫描仪的CT成像系统对样本进行扫描。 样品也用PET和微CT扫描仪的PET成像系统进行扫描。 基于PET成像系统获取的数据构建PET图像。 基于微CT成像系统获取的数据构建微CT图像。 微CT图像包括病变标记物的至少一个可视化。

公开(公告)号：US4415804A

公开(公告)日：1983-11-15

申请号：US213149

申请日：1980-12-04

申请人： Brian D. Sowerby

发明人： Brian D. Sowerby

IPC分类号： G01N23/06 ,  G01N23/203 ,  G01N23/22 ,  G01T1/178 ,  G01T1/20 ,  G01V5/00

CPC分类号： G01V5/00 ,  G01N23/203 ,  G01N23/22 ,  G01T1/178 ,  G01T1/20 ,  G01N2223/045 ,  G01N2223/053 ,  G01N2223/063 ,  G01N2223/1013 ,  G01N2223/108 ,  G01N2223/202 ,  G01N2223/6123 ,  G01N2223/613 ,  G01N2223/616 ,  G01N2223/617

摘要： An apparatus and method for quantitatively measuring the concentration of a first element or group of elements having substantially similar atomic numbers in a matrix comprising other elements having substantially different atomic numbers to that or those of said first element or group of elements is diclosed. The apparatus comprises(i) a source yielding .gamma.-rays, of sufficient energy for pair production;(ii) detecting means being associated with said source and being capable of detecting 0,511 MeV annihilation radiation;(iii) first measuring means for making a measurement of or proportional to bulk density;(iv) shielding means interposed between said source and said detecting means thereby reducing the intensity of direct source .gamma.-rays impinging on said detecting means; and(v) calculating means associated with the outputs of said detecting means and said measuring means to calculated said concentration;and wherein said first measuring means is located so as to make said measurement of or proportional to bulk density over substantially the same volume of said matrix as that in which said annihilation radiation originates.

摘要翻译： 包含具有基本上相同的原子序数的第一元素或元素组的浓度的装置和方法包括具有基本相同原子序数的其它元素的元素或与所述第一元素或元素组的元素基本上相似的元素的浓度。 该装置包括（i）产生用于对生产的足够能量的γ射线的源; （ii）与所述源相关联并且能够检测0,511MeV湮灭辐射的检测装置; （iii）用于进行体积密度测量或与体积密度成比例的第一测量装置; （iv）插入在所述源和所述检测装置之间的屏蔽装置，从而减少直接源γ射线撞击所述检测装置的强度; 和（v）与所述检测装置和所述测量装置的输出相关联的计算装置，以计算所述浓度; 并且其中所述第一测量装置被定位成在与所述湮灭辐射起源的所述矩阵的基本相同的体积上进行所述体积密度的测量或与其密度成比例。

公开(公告)号：US11965995B2

公开(公告)日：2024-04-23

申请号：US18321746

申请日：2023-05-22

申请人： Institute of Geology and Geophysics, Chinese Academy of Sciences

发明人： Yibo Wang ,  Zizhuo Ma ,  Yikang Zheng ,  Shaojiang Wu ,  Qingfeng Xue

IPC分类号： G01T1/29 ,  A61B5/00 ,  G01N21/17 ,  G01N23/046 ,  G01N29/14 ,  G01N29/22

CPC分类号： G01T1/2985 ,  G01N23/046 ,  G01N29/14 ,  G01N29/227 ,  A61B5/0095 ,  G01N21/1702 ,  G01N2021/1704 ,  G01N2223/1016 ,  G01N2223/108 ,  G01N2223/311 ,  G01N2223/419 ,  G01N2223/616

摘要： Embodiments of the present disclosure provide a multi-physical field imaging method based on PET-CT and DAS, comprising: wrapping distributed acoustic sensors on a surface of a non-metallic sample to be tested, and then placing them in a pressure device; loading triaxial pressures; preparing a tracer fluid; pumping the tracer fluid into the non-metallic sample; collecting PET images and CT images of internal structure of the non-metallic sample, meanwhile, monitoring internal acoustic emission events of the non-metallic sample in real time; combining the PET images with the CT images, to obtain PET/CT images; locating the acoustic emission events, and obtaining occurrence time and spatial location of internal structural perturbations; and analyzing a mechanism of fluid-solid coupling effect in the non-metallic sample under loaded stress. The imaging method and system of the present disclosure can accurately and reliably image the fluid-solid coupling process in the material.

公开(公告)号：US20180172848A1

公开(公告)日：2018-06-21

申请号：US15888637

申请日：2018-02-05

申请人： Minnesota Imaging and Engineering LLC

发明人： Robert Sigurd Nelson ,  William Bert Nelson

IPC分类号： G01T1/20 ,  G01N23/046 ,  G01N23/2255 ,  G01T1/22 ,  A61B6/00 ,  A61B6/03

CPC分类号： G01T1/2018 ,  A61B6/025 ,  A61B6/032 ,  A61B6/035 ,  A61B6/037 ,  A61B6/4085 ,  A61B6/4258 ,  A61B6/4417 ,  G01N23/046 ,  G01N23/2255 ,  G01N2223/108 ,  G01N2223/419 ,  G01N2223/505 ,  G01T1/22

摘要： Detector module designs for radiographic imaging include first and second layers of scintillator rods or pixel arrays oriented in first and second directions. The first and second directions are transversely oriented to define a light sharing region between the first and second layers. Encoding features may be disposed in, on or between the first and second layers, and configured to modulate propagation of optical signals therealong or therebetween.

公开(公告)号：US20140198893A1

公开(公告)日：2014-07-17

申请号：US14124654

申请日：2012-06-11

申请人： Ramsey D. Badawi ,  Kai Yang

发明人： Ramsey D. Badawi ,  Kai Yang

IPC分类号： G01N23/04 ,  G01T1/161

CPC分类号： G01N23/046 ,  A61B6/032 ,  A61B6/037 ,  A61B6/0407 ,  A61B6/4258 ,  A61B6/508 ,  A61B6/5235 ,  G01N2223/1016 ,  G01N2223/108 ,  G01N2223/419 ,  G01N2223/6126 ,  G01T1/161

摘要： Embodiments of the present invention provide methods and apparatus for imaging a tissue specimen excised during surgery with a combined positron emission tomography (PET) and micro computed tomography (micro CT) scanner. The specimen is scanned with a CT imaging system of the combined PET and micro CT scanner. The specimen is also scanned with a PET imaging system of the combined PET and micro CT scanner. A PET image is constructed based on data acquired by the PET imaging system. A micro CT image is constructed based on data acquired by the micro CT imaging system. The micro CT image includes at least one visualization of a lesion marker.

摘要翻译： 本发明的实施例提供了用组合正电子发射断层摄影（PET）和微型计算机断层摄影（micro CT）扫描仪对在手术期间切除的组织样本进行成像的方法和装置。 用PET和微型CT扫描仪的CT成像系统对样本进行扫描。 样品也用PET和微CT扫描仪的PET成像系统进行扫描。 基于PET成像系统获取的数据构建PET图像。 基于微CT成像系统获取的数据构建微CT图像。 微CT图像包括病变标记物的至少一个可视化。

公开(公告)号：US4897549A

公开(公告)日：1990-01-30

申请号：US286269

申请日：1988-12-19

申请人： Tadeusz W. Zerda ,  Bruce Miller ,  C. A. Quarles

发明人： Tadeusz W. Zerda ,  Bruce Miller ,  C. A. Quarles

IPC分类号： G01N15/08 ,  G01N23/00 ,  G01Q90/00

CPC分类号： G01N23/00 ,  G01N15/08 ,  G01N2223/01 ,  G01N2223/108 ,  G01N2223/202 ,  G01N2223/505 ,  G01N2223/649

摘要： A method is shown for measuring naturally occurring pores in a specimen material. A positron is emitted from a radioactive source and enters a material to pick up an electron to form positronium. The positronium decays very rapidly into two gamma rays. The lifetime of the positronium depends on the size of the pore it is trapped within. The larger the pore, the longer the positronium will last. By measuring the decay rate of positrons over an extended time scale in the range from 30 to 500 nsec., a near relation can be developed between positronium lifetime and pore diameter.

摘要翻译： 示出了用于测量样品材料中的天然存在的孔的方法。 正电子从放射源发射并进入材料以吸收电子以形成正电子。 正电子在两个γ射线中迅速衰减。 正电子的寿命取决于被捕获的孔隙的大小。 孔隙越大，正电子将持续时间越长。 通过在30〜500nsec范围内测量正电子在延长时间尺度上的衰减速率，可以在正电子寿命和孔径之间形成近似关系。

公开(公告)号：US3965353A

公开(公告)日：1976-06-22

申请号：US530399

申请日：1974-12-06

申请人： Albert Macovski

发明人： Albert Macovski

IPC分类号： A61B6/02 ,  A61B6/06 ,  G01N23/08 ,  G01N23/22 ,  G06T11/00 ,  G01T1/00

CPC分类号： G01N23/083 ,  A61B6/02 ,  A61B6/06 ,  A61B6/4258 ,  A61B6/483 ,  G01N23/22 ,  G06T11/003 ,  A61B6/037 ,  G01N2223/071 ,  G01N2223/1016 ,  G01N2223/108 ,  G01N2223/40 ,  G06T2211/412

摘要： A sheet beam x-ray source having energy components greater than 1.02 Mev is passed through an object under study. The emitted gamma rays due to pair production are measured using a positron-sensitive coincidence counting system on either side of the excited section. The location of each detected event is made using the positron information of each detector and the location of the excited section. An image is rapidly formed which is sensitive to the atomic number and density of materials in the cross section of the object.

摘要翻译： 具有大于1.02Mev的能量分量的片束x射线源通过被研究对象。 由于对产生而发射的γ射线是在激发部分的任一侧上使用正电子敏感的重合计数系统来测量的。 每个检测到的事件的位置是使用每个检测器的正电子信息和被激励部分的位置来进行的。 快速形成对物体横截面中材料的原子数和密度敏感的图像。