公开(公告)号：US20240316333A1

公开(公告)日：2024-09-26

申请号：US18676020

申请日：2024-05-28

申请人： CorWave SA

发明人： Carl N. BOTTERBUSCH ,  Silvere LUCQUIN ,  Pier-Paolo MONTICONE ,  Jean-Baptiste DREVET ,  Adrien GUIGNABERT ,  Patrick MENEROUD

IPC分类号： A61M60/148 ,  A61M60/178 ,  A61M60/268 ,  A61M60/40 ,  A61M60/462 ,  A61M60/531 ,  A61M60/562 ,  A61M60/569 ,  A61M60/857 ,  A61M60/876

CPC分类号： A61M60/148 ,  A61M60/178 ,  A61M60/268 ,  A61M60/40 ,  A61M60/462 ,  A61M60/531 ,  A61M60/562 ,  A61M60/569 ,  A61M60/857 ,  A61M60/876

摘要： An implantable pump system is provided, suitable for use as a left ventricular assist device (LVAD) system, having an implantable pump, an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an actuator assembly that is magnetically engagable with electromagnetic coils, so that when the electromagnetic coils are energized, the actuator assembly causes wavelike undulations to propagate along the flexible membrane to propel blood from through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

公开(公告)号：US11458295B2

公开(公告)日：2022-10-04

申请号：US16522079

申请日：2019-07-25

申请人： MI-VAD, INC.

发明人： Sudhir Kushwaha ,  Zain Khalpey

IPC分类号： A61M60/135 ,  A61M60/419 ,  A61M60/871 ,  A61M60/892 ,  A61F2/82 ,  A61F2/06 ,  A61M60/00 ,  A61M60/50 ,  A61M60/82 ,  A61M60/148 ,  A61M60/205 ,  A61M60/422 ,  A61M60/562 ,  A61M60/818 ,  A61M60/824 ,  A61M60/833 ,  A61M60/857

摘要： A ventricular assist device includes a stent for placement within a cardiac artery and arranged for placement, the stent arranged to have an open configuration defining a flow path, a rotor sized to fit within the stent and arranged for percutaneous placement the flow path, the rotor including a surface disposed about a central portion and angled with respect to the flow path and having a first plurality of magnets. A collar is sized for placement about the cardiac artery and includes a stator. A power source is coupled to the stator, and the stator and the rotor are arranged to rotate the rotor about an axis. A timing control module controls a rotational speed of the rotor. Accordingly, the surface of the rotor is arranged to move blood along the flow path in response to rotation of the rotor.

公开(公告)号：US11420041B2

公开(公告)日：2022-08-23

申请号：US16108968

申请日：2018-08-22

申请人： Berlin Heart GmbH

发明人： Dominik Karch

IPC分类号： A61M60/00 ,  A61M60/892 ,  A61M60/50 ,  G06N3/08 ,  A61M60/82 ,  A61M60/148 ,  A61M60/205 ,  A61M60/422 ,  A61M60/562

摘要： Methods are provided for controlling the speed of a pump based on a valve state index and/or for deriving a valve state from time-series signal representing a pressure difference or a flow rate. The methods may be employed in blood pump systems or in blood pump control systems.

公开(公告)号：US11406803B2

公开(公告)日：2022-08-09

申请号：US16989830

申请日：2020-08-10

申请人： Aria CV, Inc.

发明人： John Scandurra ,  Karl Vollmers

IPC分类号： A61M25/10 ,  A61M29/02 ,  A61M25/04 ,  A61M60/135 ,  A61M60/405 ,  A61M60/869 ,  A61M60/17 ,  A61M60/40 ,  A61M60/50 ,  A61M60/122 ,  A61M60/274 ,  A61M60/562 ,  A61M60/857

摘要： A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.

公开(公告)号：US11241572B2

公开(公告)日：2022-02-08

申请号：US16552102

申请日：2019-08-27

申请人： TC1 LLC

发明人： Charles Dague ,  Dan Harjes

IPC分类号： A61M60/50 ,  A61M60/17 ,  A61M60/135 ,  A61M60/562

摘要： Method and systems control a rotational speed of a blood pump during ventricular diastole. A method includes controlling a blood pump in accordance with a first segment operational mode. A controller monitors the blood flow rate through the blood pump. The controller determines, based on the blood flow rate, whether continued controlling of the blood pump per the first segment operational mode would result in the blood flow rate through the blood pump being less than a target minimum blood flow rate. In response to a determination that continued controlling of the blood pump per the first segment operational mode would result in the blood flow rate through the blood pump being less than the target minimum blood flow rate, the controller controls the rotational speed of the blood pump so that the blood flow rate through the blood pump is approximate to the target minimum blood flow rate.

公开(公告)号：US20220023523A1

公开(公告)日：2022-01-27

申请号：US17498422

申请日：2021-10-11

申请人： SENKO MEDICAL INSTRUMENT MFG. CO., LTD.

发明人： Yoshinari NIIMI ,  Masahiro KAMIYA

IPC分类号： A61M1/36 ,  A61M60/523 ,  A61M60/562 ,  A61M60/279

摘要： A blood circulation system that can be connected to a human body is provided. The system may include a roller pump, a blood removal line through which blood removed from the human body flows to the roller pump, a blood transfer line that transfers blood, which is sent from the roller pump, to the human body, means for measuring a blood removal rate provided in the blood removal line to measure a blood removal rate parameter of blood flowing through the blood removal line and a control unit, wherein the control unit is programmed to control a blood transfer rate of the roller pump by controlling a rotational speed of the roller pump with a control signal, such that a transfer rate of blood flowing through the blood transfer line is synchronized with a removal rate calculated from the blood removal rate parameter.

公开(公告)号：US20210290934A1

公开(公告)日：2021-09-23

申请号：US17260267

申请日：2019-07-17

申请人： VIADERM LLC

发明人： Allen B. Kantrowitz

IPC分类号： A61M60/148 ,  A61M60/562 ,  G06N20/00 ,  A61B5/0205 ,  A61B5/00 ,  A61B5/07

摘要： A system to optimize the operation of counter pulsatile cardiac assist devices includes a collection of intracorporeal and extracorporeal physiologic sensors that generate data. A control system in electrical communication with the collection of intracorporeal and extracorporeal physiologic sensors generates control signals for the counter pulsatile cardiac assist device based on a counter pulsating aortic pumping element based on the data. A low power transmitter is in electrical communication with the collection of sensors and the control system and sends the generated data and the control signals to an external computer for aggregation and analysis. The analysis is based on a set of inputs from an implanted counter pulsatile cardiac assist devices.

公开(公告)号：US20210170160A1

公开(公告)日：2021-06-10

申请号：US17179961

申请日：2021-02-19

申请人： CorWave SA

发明人： Louis-Emmanuel LE DUC DE LILLERS ,  Francois CORNAT ,  Jean-Baptiste DREVET ,  Carl N. BOTTERBUSCH ,  Alexandra SCHMIDT

IPC分类号： A61M60/148 ,  A61M60/268 ,  A61M60/562 ,  A61M60/40 ,  A61M60/50 ,  A61M60/871 ,  A61M60/205 ,  A61M60/135 ,  A61M60/857

摘要： An implantable pump system is provided, including an implantable blood pump suitable for use as a partial support assist device, the system further including an extracorporeal battery and a controller coupled to the implantable pump, and a programmer selectively periodically coupled to the controller to configure and adjust operating parameters of the implantable pump. The implantable pump includes a flexible membrane coupled to an electromagnetic actuator including a magnetic assembly and electromagnetic assembly, so that when the electromagnetic assembly is energized, the electromagnetic assembly causes wavelike undulations to propagate along the flexible membrane to propel blood through the implantable pump. The controller may be programmed by a programmer to operate at frequencies and duty cycles that mimic physiologic flow rates and pulsatility while operating in an efficient manner that avoids thrombus formation, hemolysis and/or platelet activation.

公开(公告)号：US20240226516A1

公开(公告)日：2024-07-11

申请号：US18614473

申请日：2024-03-22

申请人： Aria CV, Inc.

发明人： John SCANDURRA ,  Karl VOLLMERS

IPC分类号： A61M29/02 ,  A61M25/04 ,  A61M25/10 ,  A61M60/122 ,  A61M60/135 ,  A61M60/17 ,  A61M60/274 ,  A61M60/295 ,  A61M60/40 ,  A61M60/405 ,  A61M60/497 ,  A61M60/50 ,  A61M60/531 ,  A61M60/562 ,  A61M60/857 ,  A61M60/869

CPC分类号： A61M29/02 ,  A61M25/04 ,  A61M60/135 ,  A61M60/295 ,  A61M60/405 ,  A61M60/497 ,  A61M60/531 ,  A61M60/869 ,  A61M25/1018 ,  A61M25/10184 ,  A61M60/122 ,  A61M60/17 ,  A61M60/274 ,  A61M60/40 ,  A61M60/50 ,  A61M60/562 ,  A61M60/857 ,  A61M2205/33 ,  A61M2205/3303

摘要： A device for reducing pressure within a lumen includes a reservoir structured for holding a fluid therein, an injection port in fluid communication with the reservoir, a compliant body structured to expand and contract upon changes in pressure, and a conduit extending between and fluidly coupling the reservoir and the compliant body. The fluid may be a compressible or a noncompressible fluid.

公开(公告)号：US11959497B2

公开(公告)日：2024-04-16

申请号：US17360779

申请日：2021-06-28

申请人： Berlin Heart GmbH

发明人： Marcus Granegger ,  Robert Steingräber ,  Jonas Fabian Krone

IPC分类号： F04D7/00 ,  A61M60/165 ,  A61M60/196 ,  A61M60/216 ,  A61M60/419 ,  A61M60/422 ,  A61M60/515 ,  A61M60/554 ,  A61M60/562 ,  A61M60/82 ,  A61M60/822 ,  A61M60/825 ,  A61M60/857 ,  F04D3/02 ,  F04D13/06 ,  F04D29/048 ,  G01L13/00 ,  G01N11/02 ,  H02P6/182 ,  H03H17/02

CPC分类号： F04D7/00 ,  A61M60/165 ,  A61M60/196 ,  A61M60/216 ,  A61M60/419 ,  A61M60/422 ,  A61M60/515 ,  A61M60/554 ,  A61M60/562 ,  A61M60/82 ,  A61M60/822 ,  A61M60/825 ,  A61M60/857 ,  F04D3/02 ,  F04D13/0606 ,  G01L13/00 ,  G01N11/02 ,  H02P6/182 ,  H03H17/0202 ,  A61M2205/3334 ,  A61M2205/3365 ,  F04D29/048 ,  H03H2017/0205

摘要： Methods and apparatuses for determining operational parameters of a blood pump comprising a rotor which transports the blood are provided. The change in the behaviour of at least one first and one second operational parameter, independently from each other, of the pump, is determined. A determination of the flow through the pump and/or the difference in pressure across the pump and/or the viscosity of the blood takes into account the determined change in behaviour of the at least two operational parameters. A modelling for a dynamic model of the known quantities may be carried out and an estimation method using a Kalman filter may be used.