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    NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED COMPOUNDS
    1.
    发明申请
    NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED COMPOUNDS 有权
    氮氧化物释放二氮化钛化合物

    公开(公告)号：US20110282060A1

    公开(公告)日：2011-11-17

    申请号：US13111613

    申请日：2011-05-19

    Applicant: Joseph A. Hrabie ,  Frank DeRosa ,  Larry K. Keefer

    Inventor： Joseph A. Hrabie ,  Frank DeRosa ,  Larry K. Keefer

    IPC: C07D211/74 ,  C07C255/05 ,  C07D471/14 ,  C07C255/04 ,  C07F7/02 ,  C07D471/04

    CPC classification number: A61K31/78 ,  C08F8/30

    Abstract: The invention described herein provides for novel nitric oxide-releasing polymers that comprise at least two adjacent units derived from acrylonitrile monomer units and containing at least one carbon-bound diazeniumdiolate. The diazeniumdiolated acrylonitrile-derived polymers can be used in medical devices therapeutically. Accordingly, the invention also provides a method of treating a biological disorder and a method of promoting angiogenesis that includes administering a medical device comprising a nitric oxide-releasing polymer comprising at least two adjacent units of acrylonitrile before exposure to nitric oxide and at least one nitric oxide releasing N2O2− group, wherein the N2O2− group is attached directly to the polyacrylonitrile backbone, to a specific location on or within the mammal in an amount effective to treat the biological disorder or promote angiogenesis.

    Abstract translation: 本文所述的本发明提供了新一代释放氧化物的聚合物，其包含至少两个衍生自丙烯腈单体单元并且含有至少一个碳键的二氮烯鎓二硫醇盐的相邻单元。 二氮烯二烯丙酯衍生的聚合物可用于医疗器械。 因此，本发明还提供一种治疗生物学障碍的方法和促进血管发生的方法，其包括在暴露于一氧化氮和至少一种硝酸之前施用包含含有至少两个相邻单元的丙烯腈的一氧化氮释放聚合物的医疗装置 氧化物释放N2O2-基团，其中N 2 O 2基团直接连接到聚丙烯腈骨架上，以有效治疗生物学障碍或促进血管发生的量到达哺乳动物上或哺乳动物内的特定位置。

    ELECTROLYTE AND ELECTROCHEMICAL DEVICE
    3.
    发明申请
    ELECTROLYTE AND ELECTROCHEMICAL DEVICE 有权

    公开(公告)号：US20210408602A1

    公开(公告)日：2021-12-30

    申请号：US16961826

    申请日：2019-12-26

    Applicant: NINGDE AMPEREX TECHNOLOGY LIMITED

    Inventor： Chao TANG ,  Jianming ZHENG

    IPC: H01M10/0568 ,  H01M10/0567 ,  H01M10/0569 ,  C07C255/05 ,  C07D327/06 ,  H01M50/417 ,  H01M50/449 ,  H01M4/38 ,  H01M4/48 ,  H01M4/36

    Abstract: An electrolyte, including: a compound of Formula I, and at least one of a compound of Formula II or a compound of Formula III, R1, R2, R3 and R4 are each independently selected from hydrogen, fluoro, substituted or unsubstituted C1-C10 alkyl, substituted or unsubstituted C2-C10 alkenyl, substituted or unsubstituted C2-C10 alkynyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C1-C10 alkoxy, or substituted or unsubstituted C6-C12 aryloxy, wherein when substituted, the substituent is fluoro, cyano or C1-C10 alkyl; and a, d and f are each independently selected from an integer from 1 to 5, and b, c, e, g, h and i are each independently selected from an integer from 0 to 5.

    ELECTROLYTE AND ELECTROCHEMICAL APPARATUS
    4.
    发明申请
    ELECTROLYTE AND ELECTROCHEMICAL APPARATUS 有权

    公开(公告)号：US20210408597A1

    公开(公告)日：2021-12-30

    申请号：US17217211

    申请日：2021-03-30

    Applicant: Ningde Amperex Technology Limited

    Inventor： Jian Liu ,  Wenqiang Li ,  Jianming Zheng ,  Xiexue Peng

    IPC: H01M10/0567 ,  H01M10/0569 ,  H01M10/0568 ,  H01M10/0525 ,  H01M4/525 ,  C07F5/02 ,  C07C261/02 ,  C07C255/04 ,  C07C255/03 ,  C07C255/05 ,  C07C317/28

    Abstract: An electrolyte including an additive of compound of formula I, wherein n is an integer ranging from 0 to 10; R1 and R2 are each independently selected from a substituted or unsubstituted C1-C10 alkylidene group, a substituted or unsubstituted C2-C10 alkenylene group, or a substituted or unsubstituted C1-C10 alkyleneoxy group; Ai selected from CH, C, N, S, O, B or Si; A2 is selected from CH—R3, N—R3, S, O, B—R3 or SiH—R3; A3 selected from CH2, CH, C, N, S, O, B or Si; R3 is selected from hydrogen, halogen, a substituted or unsubstituted C1-C10 alkyl group, or a substituted or unsubstituted C3-C10 cycloalkyl group; Xi is selected from a substituted or unsubstituted C1-C10 alkylidene group, a substituted or unsubstituted C2-C10 alkenylene group, ═Rc═, or ═Rc—, wherein Rc is selected from a substituted or unsubstituted C2-C6 alkylidene group.

    Novel multifunctional compounds and electrolytic oxidative coupling process
    6.
    发明授权
    Novel multifunctional compounds and electrolytic oxidative coupling process 失效
    新型多功能化合物和电解氧化偶联方法

    公开(公告)号：US4871430A

    公开(公告)日：1989-10-03

    申请号：US16595

    申请日：1987-02-19

    Applicant: Stephen A. Noding

    Inventor： Stephen A. Noding

    IPC: C07C255/05 ,  C25B3/10

    CPC classification number: C25B3/10 ,  C07C255/05

    Abstract: A process for electrochemically coupling anions of organic radicals to form multifunctional compounds having the general formula ##STR1## in which R.sub.1 and R.sub.2 are independently selected from --CN, CO.sub.2 Et, --R .sub.4 CH.sub.2 Et, --CO.sub.2 R.sub.4, and --COCH.sub.3 ; R.sub.3 is Br, H, or Et, and R.sub.4 is C.sub.1-12 alkyl; and the novel compounds per se.

    Abstract translation: 电化学偶联有机基团的阴离子以形成具有通式“IMAGE”的多官能化合物的方法，其中R 1和R 2独立地选自-CN，CO 2 Et，-R 4 CH 2 Et，-CO 2 R 4和-COCH 3; R3是Br，H或Et，R4是C1-12烷基; 和新化合物本身。

    ELECTROLYTE AND ELECTROCHEMICAL DEVICE
    8.
    发明申请
    ELECTROLYTE AND ELECTROCHEMICAL DEVICE 有权

    公开(公告)号：US20210408601A1

    公开(公告)日：2021-12-30

    申请号：US16961495

    申请日：2019-12-26

    Applicant: NINGDE AMPEREX TECHNOLOGY LIMITED

    Inventor： Chao TANG ,  Lilan ZHANG ,  Junfei LIU ,  Jianming ZHENG

    IPC: H01M10/0568 ,  H01M10/0525 ,  H01M10/0569 ,  H01M10/0567 ,  C07C255/05 ,  C07D319/12

    Abstract: An electrolyte includes diglycolic anhydride and a trinitrile compound, with which the cycle performance and the high-temperature stability under over-discharge conditions of lithium-ion batteries are significantly improved. The electrolyte includes a compound of Formula I; and at least one of a compound of Formula II or a compound of Formula III; R1, R2, R3 and R4 are each independently selected from hydrogen, halo, substituted or unsubstituted C1-C10 alkyl, substituted or unsubstituted C2-C10 alkenyl, substituted or unsubstituted C2-C10 alkynyl, substituted or unsubstituted C6-C12 aryl, substituted or unsubstituted C1-C10 alkoxy, or substituted or unsubstituted C6-C12 aryloxy, wherein when substituted, the substituent is halo, cyano, or C1-C10 alkyl; and a, d and f are each independently selected from an integer from 1 to 5, and b, c, e, g, h and i are each independently selected from an integer from 0 to 5.

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