Abstract:
Methods and apparatus are provided for discontinuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a discontinuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such discontinuous circumferential treatment are provided.
Abstract:
Methods and apparatus are provided for discontinuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a discontinuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such discontinuous circumferential treatment are provided.
Abstract:
Systems, devices and methods for endoscopic procedures are provided involving accessing and manipulating tissues beyond the capabilities of traditional endoscopic instruments. Embodiments of the systems include an elongated main body (10) which has one or more independently shape-lockable sections (90, 92, 93) and a variety of instruments which are either built in to the main body or advanceable through lumens (24, 26, 58) which extend through the main body (10). Such instruments may include scopes, suction instruments, aspiration instruments, tool arms, plicators, needles, graspers, and cutters, to name a few. The ability to steer and shape-lock specific sections (90, 92, 93) of the main body (10) enables access to target locations which are typically challenging to reach and provides a stabilized platform to perform a desired procedure at the target location.
Abstract:
Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided.
Abstract:
A device for reshaping a cardiac valve (26), which is elongate and has such dimensions as to be insertable into a cardiac vessel (24). The device has two states, in a first state (K) of which the device has a shape that is adaptable to the shape of the vessel (24), and to the second state (k') of which the device is transferable from said first state (K). Further, the device comprises a fixing means (22,23;22a,23a) for fixing the ends of the device within the vessel (24), when the device is first positioned therein, a shape-changing member (20;20a) for transferring the device to the second state (K') by reshaping it, and a delay means (21;21a) for delaying said reshaping until the fixing of the ends of the device has been reinforced by keeping said device in said first state (K) until the delay means (21;21a) is resorbed.
Abstract:
The present disclosure comprises handle assemblies for intravascular treatment devices. In one embodiment, a handle assembly comprises an actuator for deflecting a distal region of an intravascular treatment device. In one embodiment, a handle assembly comprises a rotator for rotating an intravascular treatment device independently of the handle assembly. In one embodiment, a handle assembly comprises a rotation limiting element for limiting independent rotation of an intravascular treatment device relative to the handle assembly. Methods and systems for intravascular delivery, deflection and placement of an intravascular treatment device via a handle assembly of the present invention are also provided.
Abstract:
Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver an energy delivery element to a renal artery via an intravascular path. Thermal or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
Abstract:
Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment.
Abstract:
Apparatus is provided for sealing a puncture in a blood vessel using at least one device that applies an internal compressive force upon a distal surface of the vessel. The devices preferably are deployable distal of the distal surface of the vessel, then retracted proximally to provide the internal compressive force, e.g., to promote coagulation and facilitate sealing of the puncture. Additionally, the devices of the present invention optionally may be used in combination with known techniques that provide an external compressive force upon an exterior surface of a patient's skin to expedite sealing of the puncture.
Abstract:
Apparatus is provided for sealing a puncture in a blood vessel using at least one device that applies an internal compressive force upon a distal surface of the vessel. The devices preferably are deployable distal of the distal surface of the vessel, then retracted proximally to provide the internal compressive force, e.g., to promote coagulation and facilitate sealing of the puncture. Additionally, the devices of the present invention optionally may be used in combination with known techniques that provide an external compressive force upon an exterior surface of a patient's skin to expedite sealing of the puncture.