公开(公告)号：WO2005115174A3

公开(公告)日：2006-05-26

申请号：PCT/FR2005001164

申请日：2005-05-10

Applicant: CENTRE NAT RECH SCIENT ,  INST EUROPEEN BIOLOG CELLULAIR ,  UNIV MONTPELLIER I ,  UNIV MONTPELLIER II ,  PINEL ANNE-MARIE ,  VERDIE PASCAL ,  DUBS PASCALINE ,  MARTINEZ JEAN ,  SUBRA GILLES

Inventor： PINEL ANNE-MARIE ,  VERDIE PASCAL ,  DUBS PASCALINE ,  MARTINEZ JEAN ,  SUBRA GILLES

IPC: A23L1/305 ,  A61K8/64 ,  A61K38/00 ,  A61K38/05 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  C07K5/04 ,  C07K5/06 ,  C07K5/065 ,  C07K5/072 ,  C07K5/09 ,  C07K7/06 ,  C07K14/685

CPC classification number: C07K5/0815 ,  A23L33/18 ,  A61K8/64 ,  A61K38/00 ,  A61K2800/57 ,  A61Q19/02 ,  C07K5/06078 ,  C07K5/06095

Abstract: The invention relates to a dipeptide conjugate having general formula I, AA2-AA1-NH 2 , wherein A represents the radical corresponding to a monocarboxylic acid with general formula II, HOOC-R, in which: R represents a linear or branched aliphatic radical at C 1 -C 24 , which is optionally substituted by a hydroxyl group and which can comprise one or more unsaturations, preferably between 1 and 6 unsaturations, and/or which can comprise a phenyl group or lipoic acid or the reduced form thereof, dihydrolipoic acid or N-lipoyllysine; and AA1 and AA2 represent identical or different amino acids which are selected from the group containing Ala, Asn, Cys, Gln, Gly, Ile, Leu, Met, Phe, Pro, Ser, Thr, Trp, Tyr, Val, Asp, Glu, Arg, His, Lys, Orn, Dap, Dab, the corresponding homo-amino acids and the corresponding beta-amino acids in the form of enantiomers or diastereoisomers and mixtures thereof, including racemic mixtures.

Abstract translation: 本发明涉及具有通式I，AA2-AA1-NH 2的二肽缀合物，其中A表示对应于通式II的单羧酸HOOC-R的基团，其中：R表示 C 1 -C 12的直链或支链脂肪族基团，其任选被羟基取代，并且可以包含一个或多个不饱和度，优选1至6个不饱和度 ，和/或其可以包含苯基或硫辛酸或其还原形式，二氢硫辛酸或N-脂酰赖氨酸; AA1和AA2代表相同或不同的氨基酸，其选自含有Ala，Asn，Cys，Gln，Gly，Ile，Leu，Met，Phe，Pro，Ser，Thr，Trp，Tyr，Val，Asp，Glu ，Arg，His，Lys，Orn，Dap，Dab，相应的同型氨基酸和对映异构体或非对映异构体形式的相应β-氨基酸及其混合物，包括外消旋混合物。

公开(公告)号：WO2004035200A8

公开(公告)日：2004-12-02

申请号：PCT/EP0314857

申请日：2003-10-15

Applicant: CENTRE NAT RECH SCIENT ,  UNIV MONTPELLIER II ,  TREJO-MENAYO JOSE-MANUEL ,  SNAM PROGETTI ,  CONSORZIO INTERUNIVERSITARIO N ,  REPSOL YPF SA ,  ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  ROSSINI STEFANO ,  CATANI ROBERTO ,  VACCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO

Inventor： TREJO-MENAYO JOSE-MANUEL ,  ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  ROSSINI STEFANO ,  CATANI ROBERTO ,  VACCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO

IPC: B01J21/12 ,  B01J23/40 ,  B01J23/42 ,  B01J23/46 ,  B01J23/755 ,  B01J29/03 ,  B01J29/04 ,  B01J29/85 ,  B01J29/86 ,  B01J35/00 ,  C10G50/00

CPC classification number: B01J29/043 ,  B01J21/12 ,  B01J23/40 ,  B01J23/464 ,  B01J23/755 ,  B01J29/0308 ,  B01J29/041 ,  B01J29/044 ,  B01J35/002 ,  C10G50/00

Abstract: The present invention relates to the use of a silicon-based porous catalytic system for oligomerising light olefins said porous silicon-based catalytic system having an average pore diameter of between about 1 nm and about 5 nm and an acidity level of between about 150 µmol/g and about 650 µmol/g, and prepared from at least one hydrolysable silicon-based compound, or other source of silicon, and at least one non-ionic surface active agent.The invention also relates to a process for oligomerising light olefins using said silicon-based porous catalytic system, and to certain silicon-based porous catalytic systems.

Abstract translation: 本发明涉及硅基多孔催化体系用于低聚轻链烯烃的用途，所述多孔硅基催化体系的平均孔径为约1nm至约5nm，酸度为约150μmol/ g和约650μmol/ g，并且由至少一种可水解的硅基化合物或其它硅源生成，以及至少一种非离子表面活性剂。本发明还涉及使用所述 硅基多孔催化体系，以及某些硅基多孔催化体系。

公开(公告)号：WO2004035200A3

公开(公告)日：2004-10-07

申请号：PCT/EP0314857

申请日：2003-10-15

Applicant: CENTRE NAT RECH SCIENT ,  UNIV MONTPELLIER II ,  TREJO-MENAYO JOSE-MANUEL ,  SNAM PROGETTI ,  CONSORZIO INTERUNIVERSITARIO N ,  REPSOL YPF SA ,  ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  ROSSINI STEFANO ,  CATANI ROBERTO ,  VACCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO

Inventor： TREJO-MENAYO JOSE-MANUEL ,  ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  ROSSINI STEFANO ,  CATANI ROBERTO ,  VACCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO

IPC: B01J21/12 ,  B01J23/40 ,  B01J23/42 ,  B01J23/46 ,  B01J23/755 ,  B01J29/03 ,  B01J29/04 ,  B01J29/85 ,  B01J29/86 ,  B01J35/00 ,  C10G50/00 ,  B01J29/02

CPC classification number: B01J29/043 ,  B01J21/12 ,  B01J23/40 ,  B01J23/464 ,  B01J23/755 ,  B01J29/0308 ,  B01J29/041 ,  B01J29/044 ,  B01J35/002 ,  C10G50/00

Abstract: The present invention relates to the use of a silicon-based porous catalytic system for oligomerising light olefins said porous silicon-based catalytic system having an average pore diameter of between about 1 nm and about 5 nm and an acidity level of between about 150 µmol/g and about 650 µmol/g, and prepared from at least one hydrolysable silicon-based compound, or other source of silicon, and at least one non-ionic surface active agent.The invention also relates to a process for oligomerising light olefins using said silicon-based porous catalytic system, and to certain silicon-based porous catalytic systems.

Abstract translation: 本发明涉及基于硅的多孔催化体系用于低聚轻烯烃的用途，所述多孔硅基催化体系的平均孔径为约1nm至约5nm，酸度水平为约150μmol/ g至约650μmol/ g，并且由至少一种可水解的硅基化合物或其他硅来源以及至少一种非离子表面活性剂制备。本发明还涉及使用所述的所述低聚烯烃低聚烯烃的方法 硅基多孔催化体系，以及某些硅基多孔催化体系。

公开(公告)号：WO2004011444A3

公开(公告)日：2004-04-08

申请号：PCT/FR0302341

申请日：2003-07-24

Applicant: MAYOLY SPINDLER LAB ,  CENTRE NAT RECH SCIENT ,  UNIV MONTPELLIER II ,  GLOUX DAMIEN ,  CRITON MARC ,  MONTERO JEAN-LOUIS

Inventor： GLOUX DAMIEN ,  CRITON MARC ,  MONTERO JEAN-LOUIS

IPC: A61K31/42 ,  A61P1/04 ,  A61P9/00 ,  A61P11/06 ,  A61P17/02 ,  A61P17/06 ,  A61P19/02 ,  A61P29/00 ,  A61P37/08 ,  A61P43/00 ,  C07D231/10 ,  C07D261/08 ,  C07D275/02

CPC classification number: C07D261/08 ,  C07D231/10 ,  C07D275/02

Abstract: The invention concerns a method for synthesizing styryl isoxazole, styryl pyrazole and styryl isothazole derivatives in a synthesis step followed by a recrystallization in a basic alcohol medium.

Abstract translation: 本发明涉及在合成步骤中合成苯乙烯基异恶唑，苯乙烯基吡唑和苯乙烯基
异噻唑衍生物，接着在碱性醇介质中重结晶的方法。

公开(公告)号：WO03064031A2

公开(公告)日：2003-08-07

申请号：PCT/IB0300318

申请日：2003-01-31

Applicant: CENTRE NAT RECH SCIENT ,  UNIV MONTPELLIER II ,  UNIV MALAGA ,  REPSOL PETROLEO ,  CONSORZIO INTERUNIVERSITARIO N ,  ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO ,  TREJO-MENAYO JOSE-MANUEL ,  VACCCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO

Inventor： ROZIERE JACQUES ,  JONES DEBORAH ,  JACQUIN MELANIE ,  JIMENEZ-LOPEZ ANTONIO ,  RODRIGUEZ-CASTELLON ENRIQUE ,  MAIRELES-TORRES PEDRO ,  TREJO-MENAYO JOSE-MANUEL ,  VACCCARI ANGELO ,  LENARDA MAURIZIO ,  BUSCA GUIDO

IPC: B01J21/08 ,  B01J29/04 ,  B01J37/03 ,  C10G45/48 ,  C10G45/52

CPC classification number: B01J29/042 ,  B01J21/08 ,  B01J29/0316 ,  B01J29/043 ,  B01J37/033 ,  B01J37/036 ,  C10G2400/04

Abstract: Process of preparation of silicon-based multifunctional catalytic systems synthesised together with one or more surface active agents, 2) multifunctional silicon-based porous catalytic system comprising at least one porous catalytic support structurally comprising silica and at least one other metal or non-metal oxide chosen from aluminium, zirconium, and boron, said catalytic support being synthesised together with one or more surface active agents, and at least one or more catalyst chosen from among metallic elements of groups 6-10 of the periodic table of the elements, 3) the catalytic systems are useful in hydrogenation and/or decyclisation reactions of (poly)aromatic compounds, especially for improving the quality of diesel fuels and increasing their cetane number.

Abstract translation: 制备与一种或多种表面活性剂一起合成的硅基多官能催化体系的方法，2）多功能硅基多孔催化体系，其包含至少一种结构上包含二氧化硅和至少一种其它金属或非金属氧化物的多孔催化剂载体 选自铝，锆和硼，所述催化载体与一种或多种表面活性剂一起合成，以及选自元素周期表6-10族的金属元素中的至少一种或多种催化剂，3） 催化体系可用于（多）芳族化合物的氢化和/或二环化反应，特别是用于改善柴油燃料的质量和增加其十六烷值。

公开(公告)号：WO9612729A3

公开(公告)日：1996-09-06

申请号：PCT/FR9501380

申请日：1995-10-19

Applicant: UNIV MONTPELLIER II ,  COMMEYRAS AUGUSTE ,  COLLET HELENE ,  MION LOUIS ,  BENEFICE SYLVIE ,  CALAS PATRICK ,  CHOUKROUN HENRI ,  TAILLADES JACQUES ,  BIED CATHERINE

Inventor： COMMEYRAS AUGUSTE ,  COLLET HELENE ,  MION LOUIS ,  BENEFICE SYLVIE ,  CALAS PATRICK ,  CHOUKROUN HENRI ,  TAILLADES JACQUES ,  BIED CATHERINE

IPC: C07D263/44 ,  C07K1/06 ,  C07K1/08 ,  C07K1/10 ,  C07K5/062

CPC classification number: C07D263/44 ,  C07K1/084 ,  C07K1/10

Abstract: Novel method for peptide synthesis using an N-[N'-nitroso-(R')carbamoyl]amino acid as the starting compound. The compound is separated into N2, R'OH and N-carboxyanhydride of formula (II). The compound (II) together with an amino acid or peptide with at least one free alpha -amino function is introduced into a reactive medium to obtain a dipeptide or a higher peptide than the added peptide. 00000

Abstract translation: 使用N- [N'-亚硝基 - （R'）氨基甲酰基]氨基酸作为起始化合物的肽合成的新方法。 将化合物分离成式（II）的N 2，R'OH和N-羧酸酐。 将化合物（II）与具有至少一个游离α-氨基功能的氨基酸或肽一起引入反应介质中以获得比加入的肽更多的二肽或更高的肽。 00000

公开(公告)号：WO2013124574A3

公开(公告)日：2014-07-03

申请号：PCT/FR2013050331

申请日：2013-02-18

Applicant: UNIV MONTPELLIER II ,  CENTRE NAT RECH SCIENT

Inventor： HABAS JEAN-PIERRE ,  LAPINTE VINCENT ,  ULLOA HABAS AMÉLIA ,  GIANI OLIVIA

IPC: C08G59/14 ,  C08G59/02 ,  C09J163/10

CPC classification number: C08G59/027 ,  C08G59/1438 ,  C08G59/5026 ,  C08G2150/00 ,  C08G2170/00 ,  C09J163/10

Abstract: The invention relates to biosourced epoxide resins including the product of the reaction of one or more biosourced epoxide lipid derivatives with at least one cross-linking agent in the presence of at least one co-reagent selected from among the glycidyl ether derivatives of biosourced polyols, or the product of the reaction of one or more glycidyl ether derivatives of biosourced polyols with at least one cross-linking agent.

Abstract translation: 本发明涉及生物环氧化物树脂，包括一种或多种生物环氧化物脂质衍生物与至少一种交联剂在至少一种选自生物多元醇的缩水甘油醚衍生物的共试剂存在下反应的产物， 或者一种或多种生物多元醇的缩水甘油醚衍生物与至少一种交联剂反应的产物。

公开(公告)号：WO2008082602A3

公开(公告)日：2008-08-28

申请号：PCT/US2007026409

申请日：2007-12-28

Applicant: IDENIX PHARMACEUTICALS INC ,  CENTRE NAT RECH SCIENT ,  UNIV MONTPELLIER II ,  SOMMADOSSI JEAN-PIERRE ,  GOSSELIN GILLES ,  PIERRA CLAIRE ,  PERIGAUD CHRISTIAN ,  PEYROTTES SUZANNE

Inventor： SOMMADOSSI JEAN-PIERRE ,  GOSSELIN GILLES ,  PIERRA CLAIRE ,  PERIGAUD CHRISTIAN ,  PEYROTTES SUZANNE

IPC: A61K31/66 ,  C12P7/02

CPC classification number: C07H17/02 ,  A61K31/675 ,  A61K31/7056 ,  A61K31/7064 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  C07F9/65586 ,  C07F9/65616 ,  C07H19/00

Abstract: Provided herein are compounds, compositions and methods for the treatment of liver disorders, including liver cancer and metabolic diseases, such as diabetes, hyperlipidemia, atherosclerosis, and obesity. Specifically, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-cancer agents.

Abstract translation: 本文提供了用于治疗肝脏疾病的化合物，组合物和方法，包括肝癌和代谢疾病，例如糖尿病，高脂血症，动脉粥样硬化和肥胖症。 具体地，公开了核苷衍生物的化合物和组合物，其可以单独施用或与其它抗癌剂组合施用。

公开(公告)号：WO2007135273A2

公开(公告)日：2007-11-29

申请号：PCT/FR2007000815

申请日：2007-05-14

Applicant: UNIV MONTPELLIER II ,  BEN ARFA AFEF ,  CHALIER PASCALE ,  GONTARD NATHALIE ,  PREZIOSI-BELLOY LAURENCE

Inventor： BEN ARFA AFEF ,  CHALIER PASCALE ,  GONTARD NATHALIE ,  PREZIOSI-BELLOY LAURENCE

IPC: D21H21/36

CPC classification number: D21H21/36 ,  D21H19/50 ,  D21H19/54 ,  D21H27/10

Abstract: The invention concerns materials based on a woven or non-woven textile substrates coated with a matrix, characterized in that the matrix comprises one or more biodegradable polymers for controlled emission of one or more volatile antimicrobial agents incorporated in said polymers. The invention is useful in particular tor protecting products against the activity or development of microorganisms.

Abstract translation: 本发明涉及基于涂覆有基质的机织织物或非织造织物基材的材料，其特征在于，所述基质包含一种或多种可生物降解的聚合物，用于受控地排放掺入所述聚合物中的一种或多种挥发性抗微生物剂。 本发明特别有助于保护产品免受微生物的活性或发展。

公开(公告)号：WO2006067330B1

公开(公告)日：2006-09-28

申请号：PCT/FR2005003202

申请日：2005-12-20

Applicant: R S CT NAT DE LA RECH SCIENT C ,  UNIV MONTPELLIER II ,  S3F CHIMIE SOC CHIMIQUE DE FAB ,  BLANCOU HUBERT ,  GUILLEN FRANCK ,  BENFODDA ZOHRA

Inventor： BLANCOU HUBERT ,  GUILLEN FRANCK ,  BENFODDA ZOHRA

IPC: A61K31/18 ,  A61P9/00 ,  A61P27/06 ,  A61P31/00 ,  A61P31/18 ,  A61P39/02

CPC classification number: A61K31/18

Abstract: The invention concerns a pharmaceutical composition comprising compounds of formula (I): NZ 1 Z 2 Z 3 , wherein: Z 1 , Z 2 , Z 3 , independently represent: a hydrogen atom; a C 1 -C 6 alkyl group; a -SO 2 R 3 where R 3 represents a linear or branched C 1 -C 12 alkyl, alkenyl or alkynyl group, a C 3 -C 10 cycloalkyl group or a C 6 -C 10 aryl group, a (C 1 -C 6 ) alkyl (C 6 -C 14 ) aryl group, a heteroaryl group in C 5 -C 10 , provided that at least one of the Z 1 , Z 2 , Z 3 represents a group of formula (II) X-R F -(CH 2 ) n -SO 2 -, X, R F and n being such as defined in claim 1; excluding compounds for formula (I) wherein n=0 and at least one of the Z 1 , Z 2 , Z 3 groups represents CF 3 ; as well as excluding the compound (C 8 F 17 ) (C 2 H 5 )NH

Abstract translation: 本发明涉及包含式（I）化合物的药物组合物：NZ 1 Z 2 Z 3 Z 3，其中：Z < Z 1，Z 2，Z 3，Z 3独立地表示：氢原子; C 1 -C 6烷基; C 1 -C 6烷基; 其中R 3代表直链或支链C 1 -C 12烷基，其中R 3代表直链或支链C 1 -C 12 - C 1 -C 6烷基，链烯基或炔基，C 3 -C 10环烷基或C 6 -C 10 芳基，（C 1 -C 6 -C 6）烷基（C 6 -C 14）烷基（C 1 -C 6 - ）芳基，C 5 -C 10的杂芳基，条件是Z 1，Z 2中的至少一个 Z 3表示式（II）的基团XR 1 - （CH 2 N 2）n -SO 2 - ，X，R F和n如权利要求1所定义; 不包括其中n = 0的式（I）化合物和Z 1，Z 2，Z 3 3个基团中的至少一个表示CF 3， SUB> 3 ; 以及不包括化合物（C 13 H 17）NH 3（CH 2 CH 2）NH