公开(公告)号：WO2020102679A1

公开(公告)日：2020-05-22

申请号：PCT/US2019/061739

申请日：2019-11-15

Applicant: BALEEN MEDICAL LLC

Inventor： KHAIRKHAHAN, Sebastian ,  KHAIRKHAHAN, Alex

IPC: A61F2/97 ,  A61F2/01 ,  A61F2/95 ,  A61M1/34 ,  A61M5/165

Abstract: Embodiments of the present disclosure include, for example, an embolic protection system (EPS) including an inner-body having a body diameter and a distal section, and an expandable filter arranged on or adjacent at least the distal section of the inner-body. The filter is configured to include a plurality of pores, sized to allow the flow of the blood with limited interruption and capture of emboli greater than the pore size. Such embodiments may also include an expandable introducer sheath/sleeve having a sheath diameter configured to accommodate the inner-body and filter, including the distal portion, when unexpanded, as well as a tear-away (TA) sleeve having a sleeve diameter configured to accommodate the introducer sheath containing the inner-body and filter when unexpanded.

公开(公告)号：WO2018187779A1

公开(公告)日：2018-10-11

申请号：PCT/US2018/026603

申请日：2018-04-06

Applicant: SAGE SCIENCE, INC.

Inventor： BOLES, T. Christian

IPC: G01N27/26 ,  G01N27/28

Abstract: An electrophoresis cassette may include sample well(s), gel column(s) containing a separation gel, and elution modules arranged adjacent the gel column(s). A sample may be provided to the electrophoresis cassette and high-molecular weight DNA may be isolated from the sample. Single-copy DNA sequences may be cleaved on both sides of a repeat region of the DNA sequences to produce a cleaved sample, which then may be fractionated using gel electrophoresis. DNA fractions may be isolated from consecutive sections of the separation gel and subjected to PCR assays to detect single-copy sequences within the DNA fraction, said single-copy sequence containing repeat expansion sequences. The subjected DNA fractions may be electroeluted into the plurality of elution modules. A size of DNA fractions having the repeat expansion sequences may be determined. It is also determined if that size is above a normal repeat size range.

公开(公告)号：WO2018089856A1

公开(公告)日：2018-05-17

申请号：PCT/US2017/061191

申请日：2017-11-10

Applicant: ENVERID SYSTEMS, INC.

Inventor： MEIRAV, Udi ,  BIRAN, Israel ,  PERL-OLSHVANG, Sharon ,  BROWN, Shawn

IPC: B01D53/02 ,  B01D53/04 ,  B01D53/14 ,  B01D53/30

Abstract: In some embodiments, an indoor air cleaning apparatus and a method for removing at least a portion of at least one type of gas from an indoor airflow are disclosed. The apparatus may comprise a cabinet; at least one sorbent bank comprising at least one cartridge; a fan assembly comprising at least one housing including at least one housing inlet and at least one housing outlet, at least one motor and at least one impeller; and a heating element configured to operate in at least one of two modes: an active mode and an inactive mode; and a controller configured to operate in at least two modes: an adsorption mode and a regeneration mode.

Abstract translation: 在一些实施例中，公开了一种用于从室内气流去除至少一种气体的至少一部分的室内空气净化设备和方法。 该设备可以包括柜子; 至少一个吸附剂库，其包括至少一个筒; 包括至少一个壳体的风扇组件，所述至少一个壳体包括至少一个壳体入口和至少一个壳体出口，至少一个马达和至少一个叶轮; 以及加热元件，其被配置为以两种模式中的至少一种模式进行操作：活动模式和不活动模式; 以及配置成以至少两种模式操作的控制器：吸附模式和再生模式。

公开(公告)号：WO2017035254A1

公开(公告)日：2017-03-02

申请号：PCT/US2016/048439

申请日：2016-08-24

Applicant: ENVERID SYSTEMS, INC. ,  MEIRAV, Udi ,  BIRAN, Israel

Inventor： MEIRAV, Udi ,  BIRAN, Israel

IPC: F24F3/16 ,  F24F7/08 ,  B01D53/02

CPC classification number: F24F3/16 ,  B01D53/0415 ,  B01D53/0454 ,  B01D53/0462 ,  B01D2253/102 ,  B01D2253/104 ,  B01D2253/106 ,  B01D2253/108 ,  B01D2253/11 ,  B01D2253/1124 ,  B01D2253/202 ,  B01D2253/204 ,  B01D2257/10 ,  B01D2257/302 ,  B01D2257/502 ,  B01D2257/504 ,  B01D2257/708 ,  B01D2259/4508 ,  F24F3/044 ,  F24F7/08 ,  F24F2003/1621 ,  F24F2003/1639 ,  Y02C10/08

Abstract: In some embodiments, there is provided a scrubber system for cleaning return air in an HVAC unit, where the scrubber system attaches directly to an inlet of the return-air side of the HVAC unit, for example, by the mating of a flange on the system with a matching flange on the HVAC unit. The bolt-on scrubber system may comprise one or more sorbent materials, a fan for circulating return air through the sorbent, a damper-controlled inlet and a damper-controlled outlet to the attached return air side of the HVAC unit. Further, an additional air flow channel and a damper may be included in the system to control the flow of outside air into the HVAC unit. In some embodiments, the sorbents may be contained in removable inserts.

Abstract translation: 在一些实施例中，提供了一种用于清洁HVAC单元中的返回空气的洗涤器系统，其中洗涤器系统直接附接到HVAC单元的返回空气侧的入口，例如通过在 系统在HVAC设备上具有匹配的法兰。 螺栓式洗涤器系统可以包括一种或多种吸附剂材料，用于使回流空气通过吸附剂循环的风扇，阻尼器控制的入口和阻尼器控制的出口到HVAC单元的附接的返回空气侧。 此外，系统中可以包括另外的空气流动通道和阻尼器，以控制进入HVAC单元的外部空气的流动。 在一些实施方案中，吸附剂可以包含在可移除的插入物中。

公开(公告)号：WO2016054295A1

公开(公告)日：2016-04-07

申请号：PCT/US2015/053370

申请日：2015-09-30

Applicant: DXNOW INC. ,  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. ,  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY ,  KLEVAN, Leonard ,  DEMIRCI, Utkan ,  INCI, Fatih

Inventor： KLEVAN, Leonard ,  DEMIRCI, Utkan ,  INCI, Fatih

IPC: C12M1/34 ,  C12M3/00 ,  C12Q1/68

CPC classification number: B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0636 ,  B01L2300/0816 ,  C12N15/1003 ,  C12Q1/24 ,  G01N1/405

Abstract: Embodiments of the present disclosure relate to a platform for at least one of capturing, identifying and studying biological materials, and more particularly, to microfluidic channel platforms (for example) for detecting and/or identifying samples containing sperm cells, and isolating and analyzing captured sperm cells for DNA analysis (for example). In some embodiments, such microfluidic platforms integrate imaging technology. Such embodiments provide the ability to at least one of rapidly isolate and quantitate sperm cells from biological mixtures as occur in sexual assault evidence, for example, thereby enhancing identification of suspects in these cases and contributing to the safety of society.

Abstract translation: 本公开的实施方案涉及用于捕获，鉴定和研究生物材料，更具体地，涉及用于检测和/或识别含有精子细胞的样品的微流体通道平台（例如）的至少一个的平台，以及分离和分析捕获的 用于DNA分析的精子细胞（例如）。 在一些实施例中，这种微流体平台集成成像技术。 这样的实施例提供了在性攻击证据中发生的从生物混合物中快速分离和定量精子细胞中的至少一种的能力，从而增强了在这些情况下的嫌疑人的识别并有助于社会的安全。

公开(公告)号：WO2016011207A1

公开(公告)日：2016-01-21

申请号：PCT/US2015/040655

申请日：2015-07-15

Applicant: NAGAR, Ron

Inventor： NAGAR, Ron

IPC: A61J1/16

CPC classification number: A61J1/16 ,  A61M5/44

Abstract: Embodiments of the present disclosure are directed to devices, systems, and methods for controlling environmental conditions for a volume of material. In some embodiments, a handheld, portable environmental control sleeve (ECS) is disclosed which is configured for controlling at least one environmental condition of a drug contained within a drug delivery or storage device (DDSD). The ECS includes an environmental control mechanism (ECM), thermal insulation material, at least one of a power source, a processor, at least one electrical contact, at least one indicator, at least one switch, at least one environmental condition sensor, a wireless transceiver, a phase change material and at least one heat dissipater. Upon the ECS receiving at least a portion of the DDSD, the at least one environmental condition of a drug contained within the DDSD is controlled by the ECM to be within a predetermined range.

Abstract translation: 本公开的实施例涉及用于控制一定体积材料的环境条件的装置，系统和方法。 在一些实施例中，公开了一种手持式便携式环境控制套管（ECS），其被配置用于控制药物递送或存储装置（DDSD）中所含药物的至少一种环境状况。 ECS包括环境控制机构（ECM），绝热材料，电源，处理器，至少一个电触头，至少一个指示器，至少一个开关，至少一个环境条件传感器， 无线收发器，相变材料和至少一个散热器。 在ECS接收DDSD的至少一部分时，包含在DDSD内的药物的至少一个环境条件由ECM控制在预定范围内。

公开(公告)号：WO2014165317A9

公开(公告)日：2014-10-09

申请号：PCT/US2014/030629

申请日：2014-03-17

Applicant: ANCERA, INC.

Inventor： KOSER, Hur

IPC: C12Q1/02 ,  C12M1/34 ,  C12M1/42 ,  C12N13/00

Abstract: A system for determining drug effectiveness on a plurality of cells is described. The system includes flowing a ferrofluid mixed with a plurality of biological cells through an inlet portion of a cartridge, the cartridge comprising a plurality of microfluidic channels, the inlet is in communication with a portion of each of the plurality of channels, applying a magnetic field proximate at least one of the inlet portion and the plurality of micro-channels, wherein the magnetic field is configured to apply an indirect force on the mix, separating biologic cells according to at least a first type as the mix flows in a first direction; and directing at least the first type of cells toward a first sensor functionalized with receptors via at least one of the micro-channels, the sensor arranged proximate to a second portion of at least one of the micro-channels downstream from the first inlet portion.

公开(公告)号：WO2014145765A1

公开(公告)日：2014-09-18

申请号：PCT/US2014/030584

申请日：2014-03-17

Applicant: ANCERA, INC.

Inventor： KOSER, Hur

IPC: B03C1/32 ,  G01N33/49 ,  C12M1/42

CPC classification number: G01N33/54366 ,  B01L3/50273 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2300/06 ,  B01L2300/0654 ,  B01L2400/043 ,  B03C1/01 ,  B03C1/288 ,  B03C1/32 ,  B03C2201/18 ,  B03C2201/20 ,  B03C2201/26 ,  G01N15/1404 ,  G01N15/1459 ,  G01N15/1484 ,  G01N27/44786 ,  G01N33/54313 ,  G01N35/0098 ,  G01N2015/1415 ,  G01N2015/1486 ,  G01N2015/149

Abstract: Some embodiments of the present disclosure are directed to systems and methods for separating, directing, and/or extracting a target molecule from a mix of molecules and may comprise a plurality of non-magnetic beads suspended in a ferro fluid, where the non-magnetic beads may be functionalized with at least one predetermined first molecule configured to bind with a target particle. A microfluidic device may be included which may comprise at least one microfluidic channel, the device configured to dynamically and/or statically receive an amount of the mix. Magnetic field means may be included and may be configured to apply a magnetic field to at least a portion of the at least one channel to exert an indirect force on the non-magnetic beads in the ferro fluid mix, and separate the non-magnetic beads from the ferrofluid. The beads may then be directed to at least one receptor region. At least one outlet may be provided which is arranged to be in communication with the at least one microfluidic channel, the at least one outlet may be configured to receive and extract the separated non-magnetic beads from the ferrofluid.

Abstract translation: 本公开的一些实施方案涉及用于从分子混合物分离，引导和/或提取靶分子的系统和方法，并且可以包括悬浮在铁液中的多个非磁珠，其中非磁性 珠子可以被至少一个预定的第一分子功能化，其被配置为与目标颗粒结合。 可以包括微流体装置，其可以包括至少一个微流体通道，该装置被配置为动态地和/或静态地接收一定量的混合物。 可以包括磁场装置并且可以被配置为将磁场施加到至少一个通道的至少一部分，以在铁液流体混合物中的非磁珠上施加间接力，并将非磁珠 从铁磁流体。 然后将珠子引导至至少一个受体区域。 可以提供至少一个出口，其布置成与至少一个微流体通道连通，所述至少一个出口可以被配置为从铁磁流体接收和提取分离的非磁珠。

公开(公告)号：WO2014078708A1

公开(公告)日：2014-05-22

申请号：PCT/US2013/070383

申请日：2013-11-15

Applicant: ENVERID SYSTEMS, INC.

Inventor： MEIRAV, Udi ,  BIRAN, Israel ,  BECHAR, Abraham

IPC: B01D53/62

CPC classification number: B01D53/04 ,  B01D53/0454 ,  B01D2253/102 ,  B01D2253/104 ,  B01D2253/106 ,  B01D2253/116 ,  B01D2253/20 ,  B01D2253/202 ,  B01D2253/204 ,  B01D2257/302 ,  B01D2257/404 ,  B01D2257/502 ,  B01D2257/504 ,  B01D2257/708 ,  B01D2257/93 ,  B01D2259/40086 ,  B01D2259/4009 ,  B01D2259/4145 ,  B01D2259/4508 ,  B01D2259/4541 ,  B01D2259/455 ,  Y02C10/08

Abstract: An air treatment system for at least partially removing at least one gaseous contaminant contained in indoor air of a room structured for human occupants. The system may comprise an air treatment assembly having an indoor air inlet configured to receive indoor airflow directly from a room, a regenerable adsorbent material configured to adsorb at least one gaseous contaminant contained in the indoor airflow, at least one airflow element for directing the indoor airflow to flow through the air treatment assembly, an indoor air outlet for expelling the indoor air, from the air treatment assembly back into the room, a purge air inlet configured to receive and direct purge air over and/or through the adsorbent material for removal of at least a portion of the at least one gaseous contaminant, and a purge air outlet for expelling the purge air out of the air treatment assembly.

Abstract translation: 一种空气处理系统，用于至少部分地去除包含在为人类居住者构成的房间的室内空气中的至少一种气体污染物。 该系统可以包括具有室内空气入口的空气处理组件，该室内空气入口构造成从室内直接接收室内空气，被配置为吸附室内空气中所含的至少一种气体污染物的再生吸附材料，用于引导室内的至少一个气流元件 流过空气处理组件的气流，用于将室内空气排出空气的室内空气出口从空气处理组件返回到室内;净化空气入口，构造成接收和/或通过吸附材料吹扫空气以除去 至少一部分所述至少一种气态污染物，以及净化空气出口，用于将所述吹扫空气排出所述空气处理组件。

公开(公告)号：WO2013180819A1

公开(公告)日：2013-12-05

申请号：PCT/US2013/032113

申请日：2013-03-15

Applicant: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： LINDSAY, Stuart ,  ZHANG, Peiming ,  LIU, Hao

IPC: C40B20/08

CPC classification number: G01N27/26 ,  G01N33/54373 ,  G01N2400/10

Abstract: Embodiments of the present disclosure are directed to recognition tunneling methods, systems and devices for the detection of carbohydrates by measuring tunneling currents of sugars which give distinct electronic signals in a tunnel gap functionalized respectively with, for example, in some embodiments, 4(5)-(2-mercaptoethyl)-lH imideazole-2-carboxamide and 4-mercaptophenylboronic acid molecules on at least one, and preferably each electrode.

Abstract translation: 本公开的实施例涉及用于通过测量糖的隧道电流来检测碳水化合物的识别隧道方法，系统和装置，所述隧道电流在例如在一些实施例中分别功能化的隧道间隙中给出不同的电子信号，4（5） - （2-巯基乙基）-1H亚氨基咪唑-2-甲酰胺和4-巯基苯基硼酸分子在至少一个，优选每个电极上。