Abstract:
The present invention relates to an improved process for the preparation of Pentosan polysulfate of formula (I) or salt thereof, wherein R represents -SO 3 Y, and Y is at least one member selected from the group consisting of H and a pharmaceutically acceptable cation such as sodium, potassium, and magnesium which provides in particular to a narrow distribution low molecular weight, highly sulfated Pentosan polysulfate (in this instance a Xylan).
Abstract:
Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose-based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated l-a-D-( 5-deoxy-5-[I*]- iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated l-a-D-( 5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole ( 18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/ synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.
Abstract:
La présente invention concerne de nouveaux polysaccharides anioniques fonctionnalisés par au moins un dérivé d'acide hydrophobe. Ces nouveaux polysaccharides anioniques comportant des groupes hydrophobes ont une bonne biocompatibilité et leur hydrophobicité est facilement modulable sans altérer la biocompatibilité ou la stabilité. Elle concerne également une méthode de synthèse permettant de les obtenir et des compositions pharmaceutiques les comprenant.
Abstract:
Non-food plant biomass is subjected to hot-water extraction in a pressurized vessel at an elevated temperature up to about 250° C and at a pH below about 7,0, to yield an aqueous extract containing hemicellulosic components, other wood-derived compounds, and a lignocellulosic residue, The separated aqueous extract or liquor is purified and concentrated through a multi-step process producing fermentable sugars. At each stage, inhibitory chemicals such as acetic acid, lignin, and furfural are separated and eventually recovered as commercial chemicals. The lignocellulosic residue may be further processed, as a material with enhanced resistance to sorption of water, for manufacture of improved: pulp and paper, construction materials, pellet fuel, and/or other useful products.
Abstract:
The present invention relates to a method for reductive amination of a water soluble carbohydrate. An aminated water soluble carbohydrate is a prerequisite in processes for further modification of cellulose. The synthesis of this molecule comprises, providing a water soluble carbohydrate, an amine and a reducing agent, which are reacted under acidic conditions, isolated to give an aminated water soluble carbohydrate with a yield larger than 60%. The invention also relates to an aminated hemicellulose molecule with a molecular weight of at least 1 kDa, especially xyloglucan.
Abstract:
There is described a method of processing biomass which comprises the digestion of biomass material in an aqueous solvent system subjected to ultrasonic waves and separating the biomass into its constituents of lignin, hemicellulose and cellulose. There is also described a system for the processing of biomass which comprises the digestion of biomass material in an aqueous solvent system subjected to ultrasonic waves and separating the biomass into ins constituents of lignin, hemicellulose and cellulose.
Abstract:
Thermoplastic heteropolysaccharide derivatives, articles employing such thermoplastic heteropolysaccharide derivatives and methods for making such thermoplastic heteropolysaccharide derivatives are provided.
Abstract:
Die Erfindung betrifft einen heißschmelzbaren Kleber, umfassend mindestens einen durch Reaktion eines Polysaccharids (5) mit einem Imidazolid (3) in geschmolzenem Imidazol (1) gewonnenen Polysaccharidester (6). Die Erfindung betrifft weiter ein Verfahren zur Herstellung des heißschmelzbaren Klebers, bei dem Imidazol (1) geschmolzen und ein Säurechlorid (2) und/oder ein Säureanhydrid und/oder ein Lacton in und mit dem geschmolzene Imidazol (1) zu einem Imidazolid (3) umgesetzt wird, wobei dem geschmolzenen Imidazol (1) mindestens ein Polysaccharid (5) zugesetzt wird, wobei das Polysaccharid (5) mit dem Imidazolid (3) zu einem Polysaccharidester (6) umgesetzt wird.