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公开(公告)号：WO2007143497A3
公开(公告)日：2007-12-13
申请号：PCT/US2007/070074
申请日：2007-05-31
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , ROGER, Rodolfo G. , HOGARD, Michael E. , KELLY, Thomas D.
Inventor： ROGER, Rodolfo G. , HOGARD, Michael E. , KELLY, Thomas D.
Abstract: A kidney failure treatment system includes: (i) a dialysate supply; (ii) a weighing device; a control container coupled operably to the weighing device; (iii) a diffusion membrane; (iv) a drain; first and second pumps; (v) a first fluid conduit coupled fluidly to the dialysate supply and the diffusion membrane, the first fluid conduit coupled operably to the first pump; (vi) a second fluid conduit coupled fluidly to the control container and the drain, the second fluid conduit coupled operably to the first pump; and (vii) a third fluid conduit coupled fluidly to the diffusion membrane and the control conduit, the third fluid conduit coupled operably to the second pump.
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公开(公告)号：WO2010024963A1
公开(公告)日：2010-03-04
申请号：PCT/US2009/047591
申请日：2009-06-17
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , ROHDE, Justin, B. , HAN, William, W. , EVERITT, Elizabeth, A. , HOGARD, Michael, E. , LO, Ying-Cheng , COPELAND, Erin, M. , BURNS, William, P.
Inventor： ROHDE, Justin, B. , HAN, William, W. , EVERITT, Elizabeth, A. , HOGARD, Michael, E. , LO, Ying-Cheng , COPELAND, Erin, M. , BURNS, William, P.
IPC: A61M1/16
CPC classification number: A61M1/1656 , A61M1/1607 , A61M1/166 , A61M1/1674 , A61M1/1696 , A61M1/28 , A61M1/287
Abstract: A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere.
Abstract translation: 公开了一种用于监测透析液，透析液和通过透析液处理的体液的水质的系统。 该系统使用微机电系统（MEMS）传感器来检测输入水或透析液中的杂质，以及所制备的透析液。 这些传感器也可用于监测和检查被治疗患者的血液。 这些传感器包括用于诸如铵或钙的离子的离子选择性传感器，还包括适用于氯或氯胺（例如氯化物）的离子的电流计数阵列传感器。 这些传感器有助于监测城市水务主体或井的供水。 传感器可与用于从家庭或其他地方使用的水制备透析液的系统结合使用。
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公开(公告)号：WO2009045582A4
公开(公告)日：2009-06-11
申请号：PCT/US2008067368
申请日：2008-06-18
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , ROGER RODOLFO G , HOGARD MICHAEL E , TEJEDOR JOEL
Inventor： ROGER RODOLFO G , HOGARD MICHAEL E , TEJEDOR JOEL
CPC classification number: A61M1/3653 , A61M1/3655 , A61M1/3656 , A61M5/16831 , A61M2039/1005 , A61M2205/13 , A61M2205/14 , A61M2205/15
Abstract: An extracorporeal therapy machine removes blood from a patient in order to treat the blood and then return the blood to the patient. If the removal needle or the return needle is dislodged and blood is not returned, the patient may suffer a great blood loss. A new technique for detecting dislodgement uses the normal, initial values of a plurality of parameters of the patient and the therapy machine to set criteria or limits for an alarm, and then adjusts those criteria based on the later values of those parameters as they change during one therapy or over several therapies experienced by the patient.
Abstract translation: 体外治疗机器从患者去除血液以便治疗血液，然后将血液返回给患者。 如果移除针头或返回针被移开，血液不返回，则患者可能会出现大量的失血。 用于检测移位的新技术使用患者和治疗机器的多个参数的正常初始值来设置警报的标准或限制，然后基于这些参数的随后的值来调整这些标准，因为它们在 患者经历的一种疗法或多种疗法。
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公开(公告)号：WO2009061608A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/080673
申请日：2008-10-22
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , HOGARD, Michael E. , BUSBY, Donald D. , CHILDERS, Robert W. , DING, Yuanpang S. , HOLIAN, Katherine M. , JABLONSKI, Mark E. , KELLY, Thomas D. , LO, Ying-cheng , MALIEKKAL, Shincy J. , ROGER, Rodolfo G. , SMITH, Donald A. , YARDIMCI, Atif M.
Inventor： HOGARD, Michael E. , BUSBY, Donald D. , CHILDERS, Robert W. , DING, Yuanpang S. , HOLIAN, Katherine M. , JABLONSKI, Mark E. , KELLY, Thomas D. , LO, Ying-cheng , MALIEKKAL, Shincy J. , ROGER, Rodolfo G. , SMITH, Donald A. , YARDIMCI, Atif M.
CPC classification number: A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1635 , A61M1/166 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M1/288 , A61M1/341 , A61M1/3413 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3444 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M2205/12 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3393
Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
Abstract translation: 公开了一种平衡肾脏替代液流量的系统和方法。 该方法使用压力控制和压力传感装置来更精确地计量和平衡新鲜透析液和用过的透析液的流量。 平衡系统可以使用一个或两个平衡装置，例如平衡管，曲折路径或平衡室。
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公开(公告)号：WO2010011444A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/047589
申请日：2009-06-17
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , HOGARD, Michael, E.
Inventor： HOGARD, Michael, E.
IPC: A61M1/36
CPC classification number: A61M1/3653 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3656 , A61M1/3659 , A61M1/3661 , A61M2205/13 , A61M2205/3334
Abstract: A dialysis system includes: a blood filter (26); a dialysate pump (50a, 50b) connected to a dialysate portion of the blood filter (26); a blood pump (22a, 22b) connected to a blood portion of the blood filter (26), the blood pump (22a, 22b) including a diaphragm (28) that is moved in cycles to pump the blood, the cycles having a flow period and a no-flow period; a patient access device (20) in fluid communication with the blood portion of the blood filter (26), the no-flow period having a first characteristic of a property when the patient access device (20) is lodged in a patient (12) and a second characteristic of the. property when the patient access device (20) is dislodged from the patient (12); and a logic implementer (100) configured to determine that the patient access device (20) has been dislodged from the patient (12) when the second characteristic of the parameter is detected..
Abstract translation: 透析系统包括：血液过滤器（26）; 连接到血液过滤器（26）的透析液部分的透析泵（50a，50b）; 与所述血液过滤器（26）的血液部分连接的血液泵（22a，22b），所述血液泵（22a，22b）包括周期性地移动血液的振动膜（28），所述循环具有流动 期间和无流动期; 与血液过滤器（26）的血液部分流体连通的患者进入装置（20），当患者进入装置（20）存放在患者（12）中时，无流动时段具有属性的第一特征， 和第二个特点。 当患者进入装置（20）从患者（12）移出时; 以及逻辑实现器（100），被配置为当检测到所述参数的第二特征时，确定所述患者访问设备（20）已经从所述患者（12）移除。
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Patent Agency Ranking6.发明申请
公开(公告)号：WO2009009227A3
公开(公告)日：2009-03-05
申请号：PCT/US2008064865
申请日：2008-05-27
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , SLEPICKA JAMES S , PERRY MARK C , CHAN WILLIAM W , KIENMAN RICHARD E , LASSO ANGEL M , BUSBY DONALD D , ROGER RODOLFO G , HOGARD MICHAEL E
Inventor： SLEPICKA JAMES S , PERRY MARK C , CHAN WILLIAM W , KIENMAN RICHARD E , LASSO ANGEL M , BUSBY DONALD D , ROGER RODOLFO G , HOGARD MICHAEL E
CPC classification number: A61M1/28 , A61M1/1607 , A61M1/3656 , A61M2205/12 , G01N27/08
Abstract: A dialysate testing method in one embodiment includes placing electrical contacts in a dialysate flow path, measuring an electrical property of the dialysate as it flows through the flow path and past the contacts, and determining whether the dialysate has been mixed properly from the detected electrical property. A dialysate testing method in another embodiment includes flowing dialysate past a pair of electrical contacts, calculating a conductivity of the dialysate using an algorithm that takes into account a geometry of the contacts, and using the calculated conductivity to determine if the dialysate has been removed properly.
Abstract translation: 在一个实施例中的透析液测试方法包括将电触点放置在透析液流动路径中，测量透析液流过流动路径并经过触点时的电特性，并且根据检测到的电特性确定透析液是否已被适当地混合 。 另一实施例中的透析液测试方法包括使透析液流过一对电触点，使用考虑触点几何形状的算法计算透析液的电导率，并且使用计算的电导率来确定透析液是否已被适当地移除 。
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7.发明申请
公开(公告)号：WO2009009227A2
公开(公告)日：2009-01-15
申请号：PCT/US2008/064865
申请日：2008-05-27
Applicant: BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , SLEPICKA, James S. , PERRY, Mark C. , CHAN, William W. , KIENMAN, Richard E. , LASSO, Angel M. , BUSBY, Donald D. , ROGER, Rodolfo, G. , HOGARD, Michael E.
Inventor： SLEPICKA, James S. , PERRY, Mark C. , CHAN, William W. , KIENMAN, Richard E. , LASSO, Angel M. , BUSBY, Donald D. , ROGER, Rodolfo, G. , HOGARD, Michael E.
CPC classification number: A61M1/28 , A61M1/1607 , A61M1/3656 , A61M2205/12 , G01N27/08
Abstract: A dialysate testing method in one embodiment includes placing electrical contacts in a dialysate flow path, measuring an electrical property of the dialysate as it flows through the flow path and past the contacts, and determining whether the dialysate has been mixed properly from the detected electrical property. A dialysate testing method in another embodiment includes flowing dialysate past a pair of electrical contacts, calculating a conductivity of the dialysate using an algorithm that takes into account a geometry of the contacts, and using the calculated conductivity to determine if the dialysate has been removed properly.
Abstract translation: 在一个实施例中的透析液测试方法包括将电触点放置在透析液流动路径中，当透析液流过流动路径并经过触点时测量透析液的电特性，并确定透析液是否具有 从检测到的电特性中适当地混合。 另一实施例中的透析液测试方法包括使透析液流过一对电触点，使用考虑触点几何形状的算法计算透析液的电导率，并且使用计算的电导率来确定透析液是否已被适当地移除
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8.发明申请DIALYSIS SYSTEMS HAVING AIR SEPARATION CHAMBERS WITH INTERNAL STRUCTURES TO ENHANCE AIR REMOVAL 审中-公开具有内部结构的空气分离室的透析系统，以增强空气的去除
公开(公告)号：WO2009045589A3
公开(公告)日：2009-07-16
申请号：PCT/US2008068078
申请日：2008-06-25
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , CHILDERS ROBERT W , BUSBY DONALD D , HOGARD MICHAEL E , PRISCO MICHAEL R , YARDIMCI ATIF M , LAIRD JAMES C
Inventor： CHILDERS ROBERT W , BUSBY DONALD D , HOGARD MICHAEL E , PRISCO MICHAEL R , YARDIMCI ATIF M , LAIRD JAMES C
CPC classification number: A61M1/1658 , A61M1/166 , A61M1/3627 , A61M2205/128
Abstract: A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including a first sidewall and a second sidewall, a first fluid opening, a second fluid opening, and a separation wall extending from the first sidewall to the second sidewall, the separation wall having a free edge residing within the air separation chamber, the separation wall forcing the dialysis fluid to flow from one of the fluid openings around the free edge of the separation wall to the other of the openings.
Abstract translation: 透析液体盒包括限定至少一个阀室的刚性部分，所述刚性部分还限定空气分离室，所述空气分离室处于包括第一侧壁和第二侧壁的操作位置时，所述空气分离室，第一流体开口，第二流体开口 流体开口和从第一侧壁延伸到第二侧壁的分隔壁，分隔壁具有位于空气分离室内的自由边缘，分隔壁迫使透析流体围绕自由边缘的一个流体开口流动 的隔离壁到另一个开口。
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公开(公告)号：WO2009061608A4
公开(公告)日：2009-07-09
申请号：PCT/US2008080673
申请日：2008-10-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , HOGARD MICHAEL E , BUSBY DONALD D , CHILDERS ROBERT W , DING YUANPANG S , HOLIAN KATHERINE M , JABLONSKI MARK E , KELLY THOMAS D , LO YING-CHENG , MALIEKKAL SHINCY J , ROGER RODOLFO G , SMITH DONALD A , YARDIMCI ATIF M
Inventor： HOGARD MICHAEL E , BUSBY DONALD D , CHILDERS ROBERT W , DING YUANPANG S , HOLIAN KATHERINE M , JABLONSKI MARK E , KELLY THOMAS D , LO YING-CHENG , MALIEKKAL SHINCY J , ROGER RODOLFO G , SMITH DONALD A , YARDIMCI ATIF M
CPC classification number: A61M1/14 , A61M1/16 , A61M1/1605 , A61M1/1613 , A61M1/1635 , A61M1/166 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M1/288 , A61M1/341 , A61M1/3413 , A61M1/3417 , A61M1/342 , A61M1/3427 , A61M1/3434 , A61M1/3437 , A61M1/3441 , A61M1/3444 , A61M1/3458 , A61M1/3465 , A61M1/3468 , A61M2205/12 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3393
Abstract: A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber.
Abstract translation: 公开了一种用于平衡肾替代液体流动的系统和方法。 该方法使用压力控制和压力感测装置来更精确地计量和平衡新鲜透析液和用过的透析液的流动。 平衡系统可以使用一个或两个平衡装置，例如平衡管，曲折路径或平衡室。
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公开(公告)号：WO2009009226A4
公开(公告)日：2009-06-04
申请号：PCT/US2008064857
申请日：2008-05-27
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , SLEPICKA JAMES S , PERRY MARK C , CHAN WILLIAM W , KIENMAN RICHARD E , LASSO ANGEL M , BUSBY DONALD D , ROGER RODOLFO G , HOGARD MICHAEL E
Inventor： SLEPICKA JAMES S , PERRY MARK C , CHAN WILLIAM W , KIENMAN RICHARD E , LASSO ANGEL M , BUSBY DONALD D , ROGER RODOLFO G , HOGARD MICHAEL E
CPC classification number: A61M1/28 , A61M1/1607 , A61M1/3656 , A61M5/16831 , A61M5/16854 , A61M2205/12 , A61M2205/13 , A61M2205/3368 , G01N27/10
Abstract: A dialysis system instrument includes a dialysis instrument (10), a disposable pumping and valving cassette apparatus (30) operable with pumping and valving actuators of the dialysis instrument, the disposable cassette (50) including an electronic cell (100c) and electronics associated with the electronic cell, the electronics configured to determine an electrical property of a solution flowing through the electronic cell of the disposable apparatus.
Abstract translation: 透析系统仪器包括透析仪器（10），可与透析仪器的泵送和阀门致动器一起操作的一次性泵送和阀门卡匣设备（30），一次性盒子（50）包括电子单元（100c） 所述电子单元被配置为确定流过所述一次性装置的所述电子单元的溶液的电特性。
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