摘要:
The invention relates to bifunctional conjugates comprising a receptor ligand moiety and a metal binding moiety and complexes thereof with paramagnetic lanthanide or transition metals, and to the use of the metal complexes as contrast agents in magnetic resonance imaging (MRI) of tumors and other abnormalities.
摘要:
The present invention relates to novel Ruthenium catalysts and related borohydride complexes, and the use of such catalysts, inter alia, for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta-amino alcohols to form pyrazines. The present invention further relates to the novel uses of certain pyridine Ruthenium catalysts.
摘要:
A system (10) and method (30) for converting a message via a posting converter (42) is provided. At least one incoming message is received from a composition device (41). Characteristics of the message are determined. The characteristics include a target device (43) to which the message is directed and an application through which the message will be presented. An appropriate template (44) is selected for the message based on at least one of the message characteristics. The message is converted to a different format using the selected template (44). The converted message is provided for display on the target device (43).
摘要:
The present invention provides a process for preparing a metal carbene complex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron , cobalt, osmium and iridium; L denotes neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such process comprising reacting a sulfur ylide of the formula Ar 2 S=CR 1 R 2 or its precursor with an appropriate metal complex comprising a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex being also in dimeric form, at a temperature between +80 °C and -80 °C, in an inert solvent and under inert atmosphere.
摘要翻译:本发明提供了制备式(I)的金属卡宾络合物的方法:其中M是选自钌,铑,铁,钴,锇和铱的过渡金属原子; L表示与所述金属连接的中性供体配体,这些基团相同或不同; X是阴离子配体; R 1和R 2各自独立地选自氢,取代或未取代的C 1 -C 20烷基,取代或未取代的C 2 -C 20烯基,取代或未取代的环烷基,取代或未取代的杂环烷基,取代或未取代的芳基, 取代或未取代的乙烯基,a为2或3,b为1或2,该方法包括使式Ar> 2 R 2或其前体的硫叶立德与合适的金属络合物反应, 选自钌,铑,铁,钴,锇和铱的过渡金属原子,在惰性溶剂中,在+ 80℃至-80℃之间的温度下,所述金属络合物也是二聚体形式,和 在惰性气氛下。
摘要:
This invention discloses a system for safe collection of payment in return for goods, values or services, the system including a multiplicity of electronic system elements wherein each individual one of the elements has a purse storing an amount of credit for value receivable granted to the individual system element, each purse including a purse monitor operative to sign and authenticate a transaction record of each transaction in which the purse uses some of the credit for value receivable which it has been granted, and a purse control unit operative to prevent the purse, off-line, from exceeding the credit for value receivable which it has been granted.
摘要:
Aromatic olefins are produced by catalytic vinylation of aryl chlorides in the presence of a base and of a palladium complex catalyst of the formula: [R6R7P(CH2)nPR8R9]2 Pd wherein n is 3 or 4 and R6 to R9 are selected from hydrogen, alkyl, cycloalkyl, unsubstituted carbocyclic aryl or aralkyl and carbocyclic aryl or aralkyl substituted by alkyl, alkoxy or phenoxy.
摘要:
A system (10) and method (40) for efficiently reducing transcription error using hybrid voice transcription is provided. A voice stream (22) is parsed into utterances. An initial transcribed value and corresponding recognition score (113) are assigned to each utterance. A transcribed message (23) is generated and includes the initial transcribed values. A threshold is applied to the recognition scores (113) to identify those utterances with recognition scores (113) below the threshold as questionable utterances (111). At least one questionable utterance (111) is compared to other questionable utterances (111) from other calls and a group of similar questionable utterances (111) is formed. One or more of the similar questionable utterances (111) is selected from the group. A common manual transcription value (124) is received for the selected similar questionable utterances (111). The common manual transcription value (124) is assigned to the remaining similar questionable utterances (111) in the group.
摘要:
The present invention provides novel ruthenium based catalysts, and a process for preparing amines, by reacting a primary alcohol and ammonia in the presence of such catalysts, to generate the amine and water. According to the process of the invention, primary alcohols react directly with ammonia to produce primary amines and water in high yields and high turnover numbers. This reaction is catalyzed by novel ruthenium complexes, which are preferably composed of quinolinyl or acridinyl based pincer ligands.
摘要:
The present invention relates to novel Ruthenium complexes and related borohydride complexes, and their use for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including preparing polyamides (e.g., polypeptides) by reacting dialcohols and diamines or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones), cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta- amino alcohols to form pyrazines. The present invention further relates to novel uses of certain pyridine Ruthenium complexes.
摘要:
The invention relates to bifunctional conjugates comprising a receptor ligand moiety and a metal binding moiety and complexes thereof with paramagnetic lanthanide or transition metals, and to the use of the metal complexes as contrast agents in magnetic resonance imaging (MRI) of tumors and other abnormalities.