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公开(公告)号:WO2018140475A1
公开(公告)日:2018-08-02
申请号:PCT/US2018/015020
申请日:2018-01-24
Applicant: LONZA LIMITED , WEBSTER, Dale , CARPENTER, Evan
Inventor: WEBSTER, Dale , CARPENTER, Evan
Abstract: Systems and methods for dynamic automation are provided. An automation module, for example, may receive at least one map template that is selectable by a user. Based on the map template, the automation module may dynamically generate a robot deck layout map and/or procedure and also generate a series of robotic commands for a robot. The robotic commands may then be passed to the robot to carry out the automation. Accordingly, the automation may be entirely dynamic, without the need for a user to pre-program or pre-assemble all of the robotic commands prior to the automation. The automation module may thus be able to build, in real- time and/or on the fly, the robotic commands based only on the at least one map template that was selected by the user.
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公开(公告)号:WO2012065043A2
公开(公告)日:2012-05-18
申请号:PCT/US2011/060338
申请日:2011-11-11
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FLUSBERG, Benjamin , KORLACH, Jonas , WEGENER, Jeffrey , CLARK, Tyson, A. , VILFAN, Igor , KISLYUK, Andrey , TURNER, Stephen , SORENSON, Jon , TRAVERS, Kevin , HEINER, Cheryl , TOMANEY, Austin, B. , MARKS, Patrick , LEE, Jessica , JIA, Lei , WEBSTER, Dale , LYLE, John , HANES, Jeremiah , PUGLISI, Joseph
Inventor: FLUSBERG, Benjamin , KORLACH, Jonas , WEGENER, Jeffrey , CLARK, Tyson, A. , VILFAN, Igor , KISLYUK, Andrey , TURNER, Stephen , SORENSON, Jon , TRAVERS, Kevin , HEINER, Cheryl , TOMANEY, Austin, B. , MARKS, Patrick , LEE, Jessica , JIA, Lei , WEBSTER, Dale , LYLE, John , HANES, Jeremiah , PUGLISI, Joseph
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了用于表征修饰的核酸的方法,组合物和系统。 在某些优选的实施方案中,提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰包括化学修饰的碱基,酶修饰的碱基,无碱基位点,非天然碱基,二级结构和与模板核酸结合的试剂。 p>
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公开(公告)号:WO2010068289A2
公开(公告)日:2010-06-17
申请号:PCT/US2009/006517
申请日:2009-12-10
Applicant: PACIFIC BIOSCIENCES OF CALIFORNIA, INC. , FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
Inventor: FLUSBERG, Benjamin , TURNER, Stephen , LEE, Jessica , JIA, Lei , KORLACH, Jonas , SORENSON, Jon , WEBSTER, Dale , LYLE, John , TRAVERS, Kevin , HANES, Jeremiah
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q2561/113 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
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公开(公告)号:WO2010068289A3
公开(公告)日:2010-10-14
申请号:PCT/US2009006517
申请日:2009-12-10
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , TURNER STEPHEN , LEE JESSICA , JIA LEI , KORLACH JONAS , SORENSON JON , WEBSTER DALE , LYLE JOHN , TRAVERS KEVIN , HANES JEREMIAH
Inventor: FLUSBERG BENJAMIN , TURNER STEPHEN , LEE JESSICA , JIA LEI , KORLACH JONAS , SORENSON JON , WEBSTER DALE , LYLE JOHN , TRAVERS KEVIN , HANES JEREMIAH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q2561/113 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了方法,组合物和系统用于表征修饰的核酸。 在某些优选实施方案中,提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰物包括化学修饰的碱基,酶修饰的碱基,脱碱基位点,非天然碱基,二级结构和与模板核酸结合的试剂。
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公开(公告)号:WO2012065043A9
公开(公告)日:2012-12-20
申请号:PCT/US2011060338
申请日:2011-11-11
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
Inventor: FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了用于表征修饰的核酸的方法,组合物和系统。 在某些优选的实施方案中,提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰包括化学修饰的碱基,酶修饰的碱基,无碱基位点,非天然碱基,二级结构和与模板核酸结合的试剂。
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公开(公告)号:WO2012065043A3
公开(公告)日:2012-08-16
申请号:PCT/US2011060338
申请日:2011-11-11
Applicant: PACIFIC BIOSCIENCES CALIFORNIA , FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
Inventor: FLUSBERG BENJAMIN , KORLACH JONAS , WEGENER JEFFREY , CLARK TYSON A , VILFAN IGOR , KISLYUK ANDREY , TURNER STEPHEN , SORENSON JON , TRAVERS KEVIN , HEINER CHERYL , TOMANEY AUSTIN B , MARKS PATRICK , LEE JESSICA , JIA LEI , WEBSTER DALE , LYLE JOHN , HANES JEREMIAH , PUGLISI JOSEPH
CPC classification number: C12Q1/6869 , C12Q1/6837 , C12Q1/6858 , C12Q1/6874 , C12Q1/689 , C12Q2600/154 , C12Q2537/164 , C12Q2527/113 , C12Q2521/101 , C12Q2525/307 , C12Q2525/117
Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
Abstract translation: 提供了方法,组合物和系统用于表征修饰的核酸。 在某些优选实施方案中,提供单分子测序方法用于鉴定核酸序列内的修饰的核苷酸。 通过本文提供的方法可检测的修饰物包括化学修饰的碱基,酶修饰的碱基,脱碱基位点,非天然碱基,二级结构和与模板核酸结合的试剂。
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