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    INTRAOCULAR LENS
    1.
    发明申请
    INTRAOCULAR LENS 审中-公开
    内窥镜

    公开(公告)号：WO2005104995A2

    公开(公告)日：2005-11-10

    申请号：PCT/US2005/012032

    申请日：2005-04-12

    Applicant: VISIOGEN ,  NGUYEN, Tuan, Anh ,  EVANS, Scott ,  ZADNO-AZIZI, Gholam-Reza

    Inventor： NGUYEN, Tuan, Anh ,  EVANS, Scott ,  ZADNO-AZIZI, Gholam-Reza

    IPC: A61F2/16

    CPC classification number: A61F2/1616 ,  A61F2/1629 ,  A61F2/1648

    Abstract: An accommodating intraocular lens (200, 300, 400) has an anterior portion (102) including an anterior viewing element (106) and an anterior biasing element (108) connected to the anterior viewing element (106). A posterior portion (104) has a posterior viewing element (118) and a posterior biasing element (120) connected to the posterior viewing element (118). The anterior and posterior biasing elements (108, 120) are connected at first and second apices (112, 116). First and second distending members (134, 136) are connected to the posterior portion (104). The first and second distending members (134, 136) extend to locations significantly anterior of an anterior side of the posterior viewing element (118).

    Abstract translation: 容纳人工晶状体（200,300,400）具有前部（102），其包括前观察元件（106）和连接到前观察元件（106）的前偏置元件（108）。 后部部分（104）具有后观察元件（118）和连接到后观察元件（118）的后偏置元件（120）。 前和后偏置元件（108,120）在第一和第二顶点（112,116）处连接。 第一和第二扩张构件（134,136）连接到后部（104）。 第一和第二扩张构件（134,136）延伸到在后观察元件（118）的前侧的显着前方的位置。

    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION
    2.
    发明申请
    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION 审中-公开
    血管内装置治疗高血压

    公开(公告)号：WO02070039A8

    公开(公告)日：2003-10-30

    申请号：PCT/US0206929

    申请日：2002-03-01

    Applicant: THREE ARCH PARTNERS ,  LIN RICHARD Y ,  ZADNO-AZIZI GHOLAM REZA ,  ROGERS ERICA

    Inventor： LIN RICHARD Y ,  ZADNO-AZIZI GHOLAM REZA ,  ROGERS ERICA

    IPC: A61M1/10 ,  A61M1/12 ,  A61M5/142

    CPC classification number: A61M1/101 ,  A61M1/1018 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M5/14276 ,  A61M2205/3507 ,  A61M2210/1082

    Abstract: Some aspects include a mechanical pump (3) which is placed in the renal artery (4) by means of a percutaneous catheter (6), surgical implantation, or other appropriate means. This pump increases blood flow through the renal artery to the kidney (12). This increased bloodflow is perceived at the level of the macula densa as increased sodium delivery to the macula densa and the juxtaglomerular apparatus, resulting in suppression of renin production from the juxtaglomerular apparatus, with consequent reduction in angiotensin II production and aldosterone levels. This decreased aldosterone and decreased angiotensin II production lead to a reduction in blood pressure.

    Abstract translation: 一些方面包括通过经皮导管（6）放置在肾动脉（4）中的机械泵（3），手术植入或其他适当的手段。 该泵增加血液流过肾动脉至肾脏（12）。 这种增加的血流在黄斑密度处被认为是增加了向黄斑密度和近肾小球设备的钠输送，从而导致抑制肾小球体产生的肾素生成，从而导致血管紧张素II产生和醛固酮水平降低。 这减少了醛固酮，降低了血管紧张素II的产生，导致血压降低。

    ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE
    4.
    发明申请
    ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE 审中-公开
    具有增强性能的住院镜片系统

    公开(公告)号：WO2007016533A9

    公开(公告)日：2007-07-12

    申请号：PCT/US2006029852

    申请日：2006-07-31

    Applicant: VISIOGEN INC ,  NGUYEN TUAN ANH ,  ZADNO-AZIZI GHOLAM-REZA ,  EVANS SCOTT ,  PORTNEY VALDEMAR

    Inventor： NGUYEN TUAN ANH ,  ZADNO-AZIZI GHOLAM-REZA ,  EVANS SCOTT ,  PORTNEY VALDEMAR

    IPC: A61F2/16

    CPC classification number: A61F2/1613 ,  A61F2/1627 ,  A61F2/1629 ,  A61F2/1632 ,  A61F2/1648

    Abstract: An accommodating intraocular lens (100) implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power (106). The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power (118). The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.

    Abstract translation: 一种可植入眼睛的适应性眼内透镜（100）。 透镜包括具有前偏置元件的前部和具有屈光力的前光学元件（106）。 透镜还包括具有后偏置元件的后部部分和具有屈光力的后光学元件（118）。 前视神经和后视镜相对于睫状肌的作用相对移动以改变光学元件与透镜屈光力之间的分离。 透镜具有约70mg至约115mg的像差诱导力特征，以允许当透镜在眼睛中时像差引起的光学元件的相对运动，从而增加透镜的光学像差，从而增加透镜的焦深的光学像差 。 在一个变型中，透镜具有70mg至115mg的像差诱导力特征。 还公开了相关方法。

    ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE
    5.
    发明申请
    ACCOMMODATING INTRAOCULAR LENS SYSTEM WITH ABERRATION-ENHANCED PERFORMANCE 审中-公开

    公开(公告)号：WO2007016533A3

    公开(公告)日：2007-02-08

    申请号：PCT/US2006/029852

    申请日：2006-07-31

    Applicant: VISIOGEN, INC. ,  NGUYEN, Tuan, Anh ,  ZADNO-AZIZI, Gholam-Reza ,  EVANS, Scott ,  PORTNEY, Valdemar

    Inventor： NGUYEN, Tuan, Anh ,  ZADNO-AZIZI, Gholam-Reza ,  EVANS, Scott ,  PORTNEY, Valdemar

    IPC: A61F2/16

    Abstract: An accommodating intraocular lens (100) implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power (106). The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power (118). The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.

    INTRAOCULAR LENS
    6.
    发明申请
    INTRAOCULAR LENS 审中-公开
    内窥镜

    公开(公告)号：WO2005104995A3

    公开(公告)日：2006-02-23

    申请号：PCT/US2005012032

    申请日：2005-04-12

    Applicant: VISIOGEN ,  NGUYEN TUAN ANH ,  EVANS SCOTT ,  ZADNO-AZIZI GHOLAM-REZA

    Inventor： NGUYEN TUAN ANH ,  EVANS SCOTT ,  ZADNO-AZIZI GHOLAM-REZA

    IPC: A61F2/16

    CPC classification number: A61F2/1616 ,  A61F2/1629 ,  A61F2/1648

    Abstract: An accommodating intraocular lens (200, 300, 400) has an anterior portion (102) including an anterior viewing element (106) and an anterior biasing element (108) connected to the anterior viewing element (106). A posterior portion (104) has a posterior viewing element (118) and a posterior biasing element (120) connected to the posterior viewing element (118). The anterior and posterior biasing elements (108, 120) are connected at first and second apices (112, 116). First and second distending members (134, 136) are connected to the posterior portion (104). The first and second distending members (134, 136) extend to locations significantly anterior of an anterior side of the posterior viewing element (118).

    Abstract translation: 容纳人工晶状体（200,300,400）具有前部（102），其包括前观察元件（106）和连接到前观察元件（106）的前偏置元件（108）。 后部部分（104）具有后观察元件（118）和连接到后观察元件（118）的后偏置元件（120）。 前和后偏置元件（108,120）在第一和第二顶点（112,116）处连接。 第一和第二扩张构件（134,136）连接到后部（104）。 第一和第二扩张构件（134,136）延伸到在后观察元件（118）的前侧的显着前方的位置。

    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION
    7.
    发明申请
    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION 审中-公开

    公开(公告)号：WO2002070039A3

    公开(公告)日：2002-09-12

    申请号：PCT/US2002/006929

    申请日：2002-03-01

    Applicant: THREE ARCH PARTNERS ,  LIN, Richard, Y. ,  ZADNO-AZIZI, Gholam, Reza ,  ROGERS, Erica

    Inventor： LIN, Richard, Y. ,  ZADNO-AZIZI, Gholam, Reza ,  ROGERS, Erica

    IPC: A61M1/10

    Abstract: Some aspects include a mechanical pump (3) which is placed in the renal artery (4) by means of a percutaneous catheter (6), surgical implantation, or other appropriate means. This pump increases blood flow through the renal artery to the kidney (12). This increased bloodflow is perceived at the level of the macula densa as increased sodium delivery to the macula densa and the juxtaglomerular apparatus, resulting in suppression of renin production from the juxtaglomerular apparatus, with consequent reduction in angiotensin II production and aldosterone levels. This decreased aldosterone and decreased angiotensin II production lead to a reduction in blood pressure.

    INTRAOCULAR LENS SYSTEM
    9.
    发明申请
    INTRAOCULAR LENS SYSTEM 审中-公开
    内窥镜系统

    公开(公告)号：WO2004010905A2

    公开(公告)日：2004-02-05

    申请号：PCT/US2003/023077

    申请日：2003-07-24

    Applicant: VISIOGEN, INC. ,  ZADNO-AZIZI, Gholam-Reza ,  TING, Albert, C. ,  NGUYEN, Tuan, Anh ,  PORTNEY, Valdemar ,  PHAM, Hai-Minh

    Inventor： ZADNO-AZIZI, Gholam-Reza ,  TING, Albert, C. ,  NGUYEN, Tuan, Anh ,  PORTNEY, Valdemar ,  PHAM, Hai-Minh

    IPC: A61F2/16

    CPC classification number: A61F2/1613 ,  A61F2/1601 ,  A61F2/1629 ,  A61F2/164 ,  A61F2/1648 ,  A61F2/1654 ,  A61F2002/1699 ,  A61F2240/004 ,  B29D11/026

    Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

    Abstract translation: 公开了用于植入具有光轴的眼睛中的适应性眼内透镜。 该透镜包括前部，该前部又包括前部观察元件和前部偏置元件。 透镜还包括后部，后部又包括与前视觉元件间隔开的后视元件和后偏置元件。 前部和后部在眼内透镜的第一和第二顶点相交。 前部和后部和/或顶点响应于其上的力，导致观察元件之间的分离改变。 还公开了另外的实施方案和方法。

    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION
    10.
    发明申请
    INTRAVASCULAR DEVICE FOR TREATMENT OF HYPERTENSION 审中-公开
    用于治疗高血压的血管内装置

    公开(公告)号：WO2002070039A2

    公开(公告)日：2002-09-12

    申请号：PCT/US2002/006929

    申请日：2002-03-01

    Applicant: THREE ARCH PARTNERS ,  LIN, Richard, Y. ,  ZADNO-AZIZI, Gholam, Reza ,  ROGERS, Erica

    Inventor： LIN, Richard, Y. ,  ZADNO-AZIZI, Gholam, Reza ,  ROGERS, Erica

    IPC: A61M

    CPC classification number: A61M1/101 ,  A61M1/1018 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M5/14276 ,  A61M2205/3507 ,  A61M2210/1082

    Abstract: Some aspects include a mechanical pump which is placed in the renal artery by means of a percutaneous catheter, surgical implantation, or other appropriate means. This pump increases blood flow through the renal artery to the kidney. This increased flow is perceived at the level of the macula densa as increased sodium delivery to the macula densa and the juxtaglomerular apparatus, resulting in suppression of renin production from the juxtaglomerular apparatus, with consequent reduction in angiotensin II and aldosterone levels. This decreased aldosterone and decreased angiotensin II production lead to a reduction in blood pressure.

    Abstract translation: 一些方面包括通过经皮导管（6），手术植入或其它适当方式放置在肾动脉（4）中的机械泵（3）。 该泵增加通过肾动脉到肾脏的血流（12）。 这种增加的血液流量被认为是黄斑浓度水平，因为钠递送到黄斑密度和近肾小球装置，从而抑制肾小球肾脏装置的肾素生成，从而导致血管紧张素II产生和醛固酮水平的降低。 降低醛固酮和降低血管紧张素II的生成导致血压降低。

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