-
1.发明申请METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS FUMIGATUS AND ISOAMYLASE FOR SACCHARIFICATION 审中-公开从ASPERGILLUS FUMIGATUS和ISOAMYLASE使用ALPHA-AMYLASE进行鉴定的方法
公开(公告)号：WO2014093125A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/073317
申请日：2013-12-05
Applicant: DANISCO US INC.
Inventor： HUA, Ling , SCHEFFERS, Martijn , VAN BRUSSEL, Marco , VROEMEN, Casper , ZHANG, Bo , ZHANG, Zhenghong
CPC classification number: C12P19/14 , A21D8/042 , A23L7/107 , A23V2002/00 , C11D3/386 , C12C5/004 , C12C11/003 , C12N9/242 , C12N9/246 , C12P7/06 , C12P19/02 , C12Y302/01001 , C12Y302/01068 , D06L1/06 , Y02E50/17
Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmyl). AfAmyl has an optimal pH of 3.5 and is operable at 30 - 75 degrees C, allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmyl also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DPI + DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Abstract translation: 真菌α-淀粉酶由烟曲霉（AfAmyl）提供。 AfAmyl具有3.5的最佳pH，并且在30-75℃下可操作，允许酶在糖化反应中与葡糖淀粉酶和异淀粉酶组合使用。 这消除了作为分批方法进行糖化反应的必要性，其中必须重新调节pH和温度以最佳地使用α-淀粉酶或葡糖淀粉酶。 与由川崎曲霉α-淀粉酶催化的糖化产物相比，AfAmyl还催化淀粉底物对显着富集DP2和（DPI + DP2）的寡糖组合物的糖化。 这有助于例如在同时糖化和发酵过程中由发酵生物体利用寡糖组合物。
-
2.发明申请
公开(公告)号：WO2008112729A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/056601
申请日：2008-03-12
Applicant: DANISCO US INC., GENENCOR DIVISION , DUAN, Gang , QIAN, Kathy , SCHEFFERS, Martijn , SHETTY, Jayarama , VAN SOLINGEN, Pieter
Inventor： DUAN, Gang , QIAN, Kathy , SCHEFFERS, Martijn , SHETTY, Jayarama , VAN SOLINGEN, Pieter
IPC: C07K14/19
CPC classification number: C12N9/242
Abstract: A maltogenic a-amylase from Trichoderma reesei (TrAA) and variants thereof are useful in the production of high-maltose syrups from liquefied starch. Particularly high maltose concentrations are achieved when TrAA is used in the presence of a pullulanase. Expression hosts and encoding nucleic acids useful for producing TrAA and its variants also are provided.
Abstract translation: 来自里氏木霉Trichoderma reesei（TrAA）的产麦芽糖α-淀粉酶及其变体可用于从液化淀粉生产高麦芽糖糖浆。 当在支链淀粉酶存在下使用TrAA时，可以获得特别高的麦芽糖浓度。 还提供了用于生产TrAA及其变体的表达宿主和编码核酸。
-
公开(公告)号：WO2015065978A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/062578
申请日：2014-10-28
Applicant: DANISCO US INC.
Inventor： KOCOT, Boguslawa , VROEMEN, Casper , TORRES PAZMINO, Daniel E. , CANNON JR., Donald Martin , WARD, Donald E. , FOERSTER, Hans , SHETTY, Jayarama K. , CLARKSON, Kathleen A. , ALBERS, Keaton , VAN BRUSSEL, Marco , CHOW, Marina , SCHEFFERS, Martijn , SCHELLE, Michael W. , WARD, Michael , KRUITHOF, Paulien , SALA, Rafael F. , PRATT II, Robert James , RABINOVICH, Roman , BARENDS, Sharief
Abstract: Methods of improving yields of fermentation products including ethanol, improving yeast health, decreasing end of fermentation DP2 levels, among other things, are disclosed using trehalases.
Abstract translation: 使用海藻糖酶公开了提高包括乙醇在内的发酵产物的产率，提高酵母健康，减少发酵DP2水平的方法。
-
公开(公告)号：WO2017112635A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/067685
申请日：2016-12-20
Applicant: DANISCO US INC , KOOPS, Bart C. , TEUNISSEN, Paula Johanna Maira , VAN BRUSSEL, Marco , SCHEFFERS, Martijn , GUIJT, Kees-Jan , ZOU, Zhengzheng , TANG, Zhongmei , QIAN, Zhen , GE, Jing , ZHANG, Zhenghong
Inventor： KOOPS, Bart C. , TEUNISSEN, Paula Johanna Maira , VAN BRUSSEL, Marco , SCHEFFERS, Martijn , GUIJT, Kees-Jan , ZOU, Zhengzheng , TANG, Zhongmei , QIAN, Zhen , GE, Jing , ZHANG, Zhenghong
CPC classification number: C12P19/02 , C12P19/14 , C12Y302/01001 , C12Y302/01003
Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and α-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.
-
5.发明申请METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS TERREUS AND ISOAMYLASE FOR SACCHARIFICATION 审中-公开从ASPERGILLUS TERREUS和ISOAMYLASE使用ALPHA-AMYLASE进行分类的方法
公开(公告)号：WO2014099416A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/073601
申请日：2013-12-06
Applicant: DANISCO US INC.
Inventor： GE, Jing , HUA, Ling , SCHEFFERS, Martijn , VAN BRUSSEL, Marco , VROEMEN, Casper , ZHANG, Bo
CPC classification number: C12P19/14 , A21D8/042 , A23L2/382 , A23L7/107 , A23L29/35 , C11D3/38618 , C11D3/38681 , C12C5/004 , C12N9/242 , C12P7/14 , C12P19/02 , D06L1/14 , D06M16/003
Abstract: A fungal alpha-amylase is provided from Aspergillus terreus (AtAmy1). AtAmy1 has an optimal pH of 4.5 and is operable at 30 75 degrees C, allowing the enzyme to be used in combination with a glucoamylase and an isoamylase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AtAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1 + DP2) compared to the products of saccharification catalyzed by an alpha amylase from Aspergillus kawachii . This facilitates the utilization of the ligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Abstract translation: 从Aspergillus terreus（AtAmy1）提供真菌α-淀粉酶。 AtAmy1具有4.5的最佳pH，并且在30±75℃下可操作，使得酶可以在糖化反应中与葡糖淀粉酶和异淀粉酶组合使用。 这消除了作为分批方法进行糖化反应的必要性，其中必须重新调节pH和温度以最佳地使用α-淀粉酶或葡糖淀粉酶。 与由来自曲霉（Aspergillus kawachii）的α淀粉酶催化的糖化产物相比，AtAmy1还催化淀粉底物对显着富集DP2和（DP1 + DP2）的寡糖组合物的糖化。 这有利于在同时糖化和发酵过程中由发酵生物体利用该链状糖组合物。
-
Patent Agency Ranking6.发明申请METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS FUMIGATUS AND PULLULANASE FOR SACCHARIFICATION 审中-公开使用来自ASPERGILLUS FUMIGATUS和PULLULANASE的ALPHA-AMYLASE进行鉴定的方法
公开(公告)号：WO2014093123A1
公开(公告)日：2014-06-19
申请号：PCT/US2013/073304
申请日：2013-12-05
Applicant: DANISCO US INC.
Inventor： HUA, Ling , SCHEFFERS, Martijn , VAN BRUSSEL, Marco , VROEMEN, Casper , ZHANG, Bo , ZHANG, Zhenghong
CPC classification number: C12P19/02 , A21D8/042 , A23L2/382 , C11D3/38636 , C12C5/004 , C12C7/04 , C12C7/16 , C12C11/003 , C12C12/04 , C12G3/02 , C12N9/242 , C12P7/14 , C12P19/14 , C12Y302/01001 , C13K1/06 , D06L1/06
Abstract: A fungal alpha-amylase is provided from Aspergillus fumigatus (AfAmy1). AfAmy1 has an optimal pH of 3.5 and is operable at 30 - 75 degrees C, allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AfAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1 + DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii . This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Abstract translation: 从烟曲霉（AfAmy1）提供真菌α-淀粉酶。 AfAmy1具有3.5的最佳pH，并且在30-75℃下可操作，使酶在糖化反应中与葡糖淀粉酶和支链淀粉酶组合使用。 这消除了作为分批方法进行糖化反应的必要性，其中必须重新调节pH和温度以最佳地使用α-淀粉酶或葡糖淀粉酶。 与由川曲霉α-淀粉酶催化的糖化产物相比，AfAmy1还催化淀粉底物对显着富含DP2和（DP1 + DP2）的寡糖组合物的糖化。 这有助于例如在同时糖化和发酵过程中由发酵生物体利用寡糖组合物。
-
公开(公告)号：WO2017112643A1
公开(公告)日：2017-06-29
申请号：PCT/US2016/067708
申请日：2016-12-20
Applicant: DANISCO US INC. , KOOPS, Bart C. , TEUNISSEN, Paula Johanna Maria , VAN BRUSSEL, Marco , SCHEFFERS, Martijn , GUIJT, Kees-Jan , ZOU, Zhengzheng , TANG, Zhongmei , QIAN, Zhen , GE, Jing , ZHANG, Zhenghong
Inventor： KOOPS, Bart C. , TEUNISSEN, Paula Johanna Maria , VAN BRUSSEL, Marco , SCHEFFERS, Martijn , GUIJT, Kees-Jan , ZOU, Zhengzheng , TANG, Zhongmei , QIAN, Zhen , GE, Jing , ZHANG, Zhenghong
CPC classification number: C12P19/02 , C12P19/14 , C12Y302/01001 , C12Y302/01003
Abstract: Described are methods and compositions relating to granular starch-converting glucoamylases and α-amylases. The enzymes can be used to perform enzymatic starch hydrolysis of granular starch at or below the gelatinization temperature of insoluble granular starch.
-
8.发明申请METHOD OF USING ALPHA-AMYLASE FROM ASPERGILLUS TERREUS AND PULLULANASE FOR SACCHARIFICATION 审中-公开使用来自青蒿素和富勒烯的ALPHA-AMYLASE进行分离的方法
公开(公告)号：WO2014099415A1
公开(公告)日：2014-06-26
申请号：PCT/US2013/073594
申请日：2013-12-06
Applicant: DANISCO US INC.
Inventor： GE, Jing , HUA, Ling , SCHEFFERS, Martijn , VAN BRUSSEL, Marco , VROEMEN, Casper , ZHANG, Bo
CPC classification number: C12P19/14 , A21D8/042 , A23L2/382 , A23L7/107 , A23L29/35 , C11D3/386 , C12C5/004 , C12C7/04 , C12C7/16 , C12C11/003 , C12C12/04 , C12N9/242 , C12P7/06 , C12P7/14 , C12P19/02 , C12P2203/00 , C13K1/06 , C13K11/00 , D06L1/06 , Y02E50/17
Abstract: A fungal alpha-amylase is provided from Aspergillus terreus (AtAmy1). AtAmy1 has an optimal pH of 4.5 and is operable at 30 75 degrees C, allowing the enzyme to be used in combination with a glucoamylase and a pullulanase in a saccharification reaction. This obviates the necessity of running a saccharification reaction as a batch process, where the pH and temperature must be readjusted for optimal use of the alpha-amylase or glucoamylase. AtAmy1 also catalyzes the saccharification of starch substrates to an oligosaccharide composition significantly enriched in DP2 and (DP1 + DP2) compared to the products of saccharification catalyzed by an alpha-amylase from Aspergillus kawachii. This facilitates the utilization of the oligosaccharide composition by a fermenting organism in a simultaneous saccharification and fermentation process, for example.
Abstract translation: 从Aspergillus terreus（AtAmy1）提供真菌α-淀粉酶。 AtAmy1具有4.5的最佳pH，并且在30±75℃下可操作，使得酶可在糖化反应中与葡糖淀粉酶和支链淀粉酶组合使用。 这消除了作为分批方法进行糖化反应的必要性，其中必须重新调节pH和温度以最佳地使用α-淀粉酶或葡糖淀粉酶。 与由来自曲霉（Aspergillus kawachii）的α-淀粉酶催化的糖化产物相比，AtAmy1还催化淀粉底物对显着富含DP2和（DP1 + DP2）的寡糖组合物的糖化。 这有助于例如在同时糖化和发酵过程中由发酵生物体利用寡糖组合物。
-
公开(公告)号：WO2009048487A1
公开(公告)日：2009-04-16
申请号：PCT/US2008/004556
申请日：2008-04-08
Applicant: DANISCO US, INC., GENENCOR DIVISION , AEHLE, Wolfgang , BOTT, Richard R. , NIKOLAEV, Igor , SCHEFFERS, Martijn , VAN SOLINGEN, Piet , VROEMEN, Casper
Inventor： AEHLE, Wolfgang , BOTT, Richard R. , NIKOLAEV, Igor , SCHEFFERS, Martijn , VAN SOLINGEN, Piet , VROEMEN, Casper
CPC classification number: C12N9/2428 , Y02E50/17
Abstract: The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells.
Abstract translation: 本发明涉及葡糖淀粉酶变体。 特别地，本发明涉及葡糖淀粉酶的淀粉结合结构域（SBD）中的变体。 本发明还涉及与相应的母体葡糖淀粉酶相比具有改变的性质（例如，改善的热稳定性和/或增加的比活性）的变体。 本发明还提供了包含变体葡糖淀粉酶的酶组合物; 包含编码变体的多核苷酸的DNA构建体; 以及在宿主细胞中产生葡糖淀粉酶变体的方法。
-
10.发明申请TRICHODERMA REESE A-AMYLASE ENHANCES SACCHARIFICATION OF CORN STARCH 审中-公开TRICHODERMA REESE A-AMYLASE增强了玉米淀粉的分离
公开(公告)号：WO2008112727A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/056597
申请日：2008-03-12
Applicant: DANISCO US INC., GENENCOR DIVISION , DUAN, Gang , QIAN, Kathy , SCHEFFERS, Martijn , SHETTY, Jayarama K. , VAN SOLINGEN, Pieter
Inventor： DUAN, Gang , QIAN, Kathy , SCHEFFERS, Martijn , SHETTY, Jayarama K. , VAN SOLINGEN, Pieter
CPC classification number: C12N9/242
Abstract: A maltogenic α-amylase from Trichoderma reesei (TrAA) and variants thereof in the presence of a glucoamylase are useful in the production of high-glucose syrups from liquefied starch, where the high-glucose syrups produced thereby contain at least about 97% glucose. In this process, TrAA advantageously suppresses the reversion of glucose to malto-oligosaccharides. Expression hosts and encoding nucleic acids useful for producing TrAA and its variants also are provided.
Abstract translation: 在葡糖淀粉酶存在下，来自里氏木霉（TrAA）的麦芽糖α-淀粉酶及其变体可用于从液化淀粉生产高葡萄糖浆，其中由此产生的高葡萄糖浆含有至少约97％的葡萄糖。 在此过程中，TrAA有利地抑制了葡萄糖向麦芽寡糖的转化。 还提供了用于产生TrAA及其变体的表达宿主和编码核酸。
-
-
-
-
-
-
-
-
-
Search Results
14
records
(took 0.028 seconds)
